{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T23:39:24Z","timestamp":1785368364148,"version":"3.55.0"},"reference-count":119,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.abb.2024.110045","type":"journal-article","created":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T06:16:08Z","timestamp":1716617768000},"page":"110045","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["The impact of volatile anesthetics and propofol on phosphatidylinositol 4,5-bisphosphate signaling"],"prefix":"10.1016","volume":"757","author":[{"given":"Ayaan","family":"Parikh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Krogman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.abb.2024.110045_bib1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1080\/08820139.2017.1373905","article-title":"Volatile anesthetics and immunity","volume":"46","author":"Sedghi","year":"2017","journal-title":"Immunol. Invest."},{"issue":"1\u20132","key":"10.1016\/j.abb.2024.110045_bib2","first-page":"238","article-title":"Navarro and others, mouse anesthesia: the art and science","volume":"62","author":"Kaela","year":"2021","journal-title":"ILAR J."},{"key":"10.1016\/j.abb.2024.110045_bib3","series-title":"Propofol","author":"Folino","year":"2023"},{"key":"10.1016\/j.abb.2024.110045_bib4","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1073\/pnas.2004259117","article-title":"Studies on the mechanism of general anesthesia","volume":"117","author":"Pavel","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"9","key":"10.1016\/j.abb.2024.110045_bib5","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1085\/jgp.201812118","article-title":"The voltage-gated sodium channel pore exhibits conformational flexibility during slow inactivation","volume":"150","author":"Chatterjee","year":"2018","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.abb.2024.110045_bib6","unstructured":"Iqbal, F., Thompson, A. J., Riaz, S., Pehar, M., Rice, T., & Syed, N. I. Anesthetics: from modes of action to unconsciousness and neurotoxicity. J. Neurophysiol..."},{"issue":"5391","key":"10.1016\/j.abb.2024.110045_bib7","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1126\/science.282.5391.1141","article-title":"PIP2 and PIP as determinants for ATP inhibition of KATP channels","volume":"282","author":"Baukrowitz","year":"1998","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib8","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1124\/pr.114.009555","volume":"67","author":"Veldhuis","year":"2015","journal-title":"Pharmacological Reviews January 1"},{"key":"10.1016\/j.abb.2024.110045_bib9","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms13873","article-title":"Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D","volume":"7","author":"Petersen","year":"2016","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib10","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3390\/membranes13020250","article-title":"Cholesterol regulation of membrane proteins revealed by two-color super-resolution imaging","volume":"13","author":"Yuan","year":"2023","journal-title":"Membranes"},{"issue":"4","key":"10.1016\/j.abb.2024.110045_bib11","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/j.1365-2567.2006.02531.x","article-title":"Expression of GM1, a marker of lipid rafts, defines two subsets of human monocytes with differential endocytic capacity and lipopolysaccharide responsiveness","volume":"120","author":"Moreno-Altamirano","year":"2007","journal-title":"Immunology"},{"issue":"5","key":"10.1016\/j.abb.2024.110045_bib12","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1194\/jlr.TR120000658","article-title":"Lipid rafts as a therapeutic target","volume":"61","author":"Sviridov","year":"2020","journal-title":"J. Lipid Res."},{"issue":"5","key":"10.1016\/j.abb.2024.110045_bib13","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1128\/IAI.03118-14","article-title":"The assembly of GM1 glycolipid- and cholesterol-enriched raft-like membrane microdomains is important for giardial encystation","volume":"83","author":"De","year":"2015","journal-title":"Infect. Immun."},{"issue":"5","key":"10.1016\/j.abb.2024.110045_bib14","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1194\/jlr.TR119000427","article-title":"Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases","volume":"61","author":"Grassi","year":"2020","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.abb.2024.110045_bib15","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.biopha.2018.08.063","article-title":"Volatile anesthetics sevoflurane targets leukemia stem\/progenitor cells via Wnt\/\u03b2-catenin inhibition","volume":"107","author":"Ruan","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s41392-021-00762-6","article-title":"Wnt\/\u03b2-catenin signalling: function, biological mechanisms, and therapeutic opportunities","volume":"7","author":"Liu","year":"2022","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.abb.2024.110045_bib17","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1097\/00000542-200412000-00012","article-title":"The inhibitory effects of isoflurane on protein tyrosine phosphorylation\u2013modulated contraction of rat aortic smooth muscle","volume":"101","author":"Jingui","year":"2004","journal-title":"Anesthesiology"},{"issue":"694","key":"10.1016\/j.abb.2024.110045_bib18","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.abc6612","article-title":"Emerging roles of PLC\u03b31 in endothelial biology","volume":"14","author":"Chen","year":"2021","journal-title":"Sci. Signal."},{"key":"10.1016\/j.abb.2024.110045_bib19","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.bbrc.2021.09.012","article-title":"Phospholipase C\u03b31 represses colorectal cancer growth by inhibiting the Wnt\/\u03b2-catenin signaling axis","volume":"577","author":"Kyeong","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"10.1016\/j.abb.2024.110045_bib20","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/0006-2952(94)90403-0","article-title":"Halothane and isoflurane enhance basal and carbachol-stimulated inositol(1,4,5)triphosphate formation in SH-SY5Y human neuroblastoma cells","volume":"47","author":"Smart","year":"1994","journal-title":"Biochem. Pharmacol."},{"issue":"10","key":"10.1016\/j.abb.2024.110045_bib21","doi-asserted-by":"crossref","first-page":"6760","DOI":"10.1074\/jbc.272.10.6760","article-title":"Tubulin, Gq, and phosphatidylinositol 4,5-bisphosphate interact to regulate phospholipase Cbeta1 signaling","volume":"272","author":"Popova","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"31","key":"10.1016\/j.abb.2024.110045_bib22","doi-asserted-by":"crossref","first-page":"6067","DOI":"10.1523\/JNEUROSCI.2304-18.2019","article-title":"G\u03b1q sensitizes TRPM8 to inhibition by PI(4,5)P2 depletion upon receptor activation","volume":"39","author":"Liu","year":"2019","journal-title":"J. Neurosci."},{"key":"10.1016\/j.abb.2024.110045_bib23","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/wmts.102","article-title":"L-type Ca2+ channels in heart and brain","volume":"3","author":"Striessnig","year":"2014","journal-title":"WIREs Membr Transp Signal"},{"issue":"4","key":"10.1016\/j.abb.2024.110045_bib24","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1213\/ANE.0b013e31824762f0","article-title":"The volatile anesthetic isoflurane prevents ventilator-induced lung injury via phosphoinositide 3-kinase\/Akt signaling in mice","volume":"114","author":"Faller","year":"2012","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.abb.2024.110045_bib25","first-page":"199","article-title":"Inhaled anesthetic potency results from charge delocalization and stability of a charge transfer Complex at an electron-transfer site in microtubules: a unitary theory of general anesthesia","volume":"8","author":"Duncan","year":"2016","journal-title":"International Journal of Chemical Modeling"},{"key":"10.1016\/j.abb.2024.110045_bib26","series-title":"Volatile Anesthetic Interference with Microtubule-Modulated Gq-Coupled Receptor Systems at the PLC Level Disrupts a Plethora of Divergent Downstream Targets Signaling the Demise of Multi-Site-Multi-Mechanism Models","author":"Duncan","year":"2020"},{"key":"10.1016\/j.abb.2024.110045_bib27","series-title":"StatPearls. Treasure Island (FL)","article-title":"Biochemistry, calcium channels","author":"Cooper","year":"2022"},{"key":"10.1016\/j.abb.2024.110045_bib28","article-title":"IP3 mediated global Ca2+ signals arise through two temporally and spatially distinct modes of Ca2+ release","volume":"9","author":"Jeffrey","year":"2020","journal-title":"Elife"},{"issue":"7","key":"10.1016\/j.abb.2024.110045_bib29","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1038\/sj.bjp.0702711","article-title":"Microtubule cytoskeleton involvement in muscarinic suppression of voltage-gated calcium channel current in Guinea-pig ileal smooth muscle","volume":"127","author":"Unno","year":"1999","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.abb.2024.110045_bib30","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3389\/fnmol.2018.00258","article-title":"Physiological roles and therapeutic potential of Ca2+ activated potassium channels in the nervous system","volume":"11","author":"Kshatri","year":"2018","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.abb.2024.110045_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2020.108261","article-title":"Maintenance of CaV2.2 channel-current by PIP2 unveiled by neomycin in sympathetic neurons of the rat","volume":"682","author":"Castro","year":"2020","journal-title":"Arch. Biochem. Biophys."},{"issue":"4","key":"10.1016\/j.abb.2024.110045_bib32","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1085\/jgp.201411245","article-title":"Voltage-dependent regulation of CaV2.2 channels by Gq-coupled receptor is facilitated by membrane-localized \u03b2 subunit","volume":"144","author":"Keum","year":"2014","journal-title":"J. Gen. Physiol."},{"issue":"5","key":"10.1016\/j.abb.2024.110045_bib33","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.bbalip.2015.01.011","article-title":"Lipid agonism: the PIP2 paradigm of ligand-gated ion channels","volume":"1851","author":"Hansen","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib34","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/sj.emboj.7600494","article-title":"A phospholipid sensor controls mechanogating of the K+ channel TREK-1","volume":"24","author":"Chemin","year":"2005","journal-title":"EMBO J."},{"issue":"38","key":"10.1016\/j.abb.2024.110045_bib35","doi-asserted-by":"crossref","first-page":"11959","DOI":"10.1073\/pnas.1500525112","article-title":"Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling","volume":"112","author":"Baumgart","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.abb.2024.110045_bib36","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.59839","article-title":"Mechanistic insights into volatile anesthetic modulation of K2P channels","volume":"9","author":"Wague","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.abb.2024.110045_bib37","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/nature12360","article-title":"Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate","volume":"499","author":"Posor","year":"2013","journal-title":"Nature"},{"issue":"14","key":"10.1016\/j.abb.2024.110045_bib38","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.1091\/mbc.e11-04-0362","article-title":"Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size","volume":"22","author":"Antonescu","year":"2011","journal-title":"Mol. Biol. Cell"},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib39","doi-asserted-by":"crossref","first-page":"P144","DOI":"10.1016\/j.devcel.2013.03.010","article-title":"Endosomal type i\u03b3 PIP 5-kinase controls EGF receptor lysosomal sorting","volume":"25","author":"Sun","year":"2013","journal-title":"Dev. Cell"},{"issue":"13","key":"10.1016\/j.abb.2024.110045_bib40","doi-asserted-by":"crossref","first-page":"jcs244327","DOI":"10.1242\/jcs.244327","article-title":"Bidirectional transfer of homeoprotein EN2 across the plasma membrane requires PIP2","volume":"133","author":"Amblard","year":"2020","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.abb.2024.110045_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2019.00419","article-title":"Anionic lipids: a pipeline connecting key players of plant cell division","volume":"10","author":"Caillaud","year":"2019","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.abb.2024.110045_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2021.116190","article-title":"The chemistry and biology of phosphatidylinositol 4-phosphate at the plasma membrane","volume":"40","author":"Batrouni","year":"2021","journal-title":"Bioorg. Med. Chem."},{"issue":"Pt 17","key":"10.1016\/j.abb.2024.110045_bib43","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1113\/jphysiol.2010.192153","article-title":"Phosphoinositides: lipid regulators of membrane proteins","volume":"588","author":"Falkenburger","year":"2010","journal-title":"J. Physiol."},{"issue":"21","key":"10.1016\/j.abb.2024.110045_bib44","doi-asserted-by":"crossref","first-page":"8342","DOI":"10.3390\/ijms21218342","article-title":"Review of PIP2 in cellular signaling, functions and diseases","volume":"21","author":"Mandal","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.abb.2024.110045_bib45","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.bpj.2019.07.047","article-title":"PIP2 reshapes membranes through asymmetric desorption","volume":"117","author":"Shukla","year":"2019","journal-title":"Biophys. J."},{"key":"10.1016\/j.abb.2024.110045_bib46","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/nature05185","article-title":"Phosphoinositides in cell regulation and membrane dynamics","volume":"443","author":"Di Paolo","year":"2006","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib47","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1021\/acsnano.8b05286","article-title":"Soft hyaluronic gels promote cell spreading, stress fibers, focal adhesion, and membrane tension by phosphoinositide signaling, not traction force","volume":"13","author":"Mandal","year":"2019","journal-title":"ACS Nano"},{"issue":"9","key":"10.1016\/j.abb.2024.110045_bib48","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.tibs.2019.04.001","article-title":"Tools for understanding nanoscale lipid regulation of ion channels","volume":"44","author":"Robinson","year":"2019","journal-title":"Trends Biochem. Sci."},{"issue":"4","key":"10.1016\/j.abb.2024.110045_bib49","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1124\/pr.114.009217","article-title":"Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer","volume":"66","author":"Bruntz","year":"2014","journal-title":"Pharmacol. Rev."},{"issue":"28","key":"10.1016\/j.abb.2024.110045_bib50","doi-asserted-by":"crossref","first-page":"8322","DOI":"10.1021\/jp401414y","article-title":"Quantum and all-atom molecular dynamics simulations of protonation and divalent ion binding to phosphatidylinositol 4,5-bisphosphate (PIP2)","volume":"117","author":"Slochower","year":"2013","journal-title":"J. Phys. Chem. B"},{"issue":"12","key":"10.1016\/j.abb.2024.110045_bib51","first-page":"P4704","article-title":"Lateral distribution of phosphatidylinositol 4,5-bisphosphate in membranes regulates formin- and ARP2\/3-mediated actin nucleation","volume":"294","author":"Bucki","year":"2019","journal-title":"Membrane Biology"},{"key":"10.1016\/j.abb.2024.110045_bib52","article-title":"Divalent cations bind to phosphoinositides to induce ion and isomer specific propensities for nano-cluster initiation in bilayer membranes","volume":"7192208192208","author":"Bradley","year":"2020","journal-title":"R. Soc. Open Sci."},{"issue":"7","key":"10.1016\/j.abb.2024.110045_bib53","doi-asserted-by":"crossref","first-page":"3387","DOI":"10.1021\/ja208640t","article-title":"Divalent cation-induced cluster formation by polyphosphoinositides in model membranes","volume":"134","author":"Wang","year":"2012","journal-title":"J. Am. Chem. Soc."},{"issue":"34","key":"10.1016\/j.abb.2024.110045_bib54","doi-asserted-by":"crossref","first-page":"8241","DOI":"10.1021\/bi9007879","article-title":"Calcium-dependent lateral organization in phosphatidylinositol 4,5-bisphosphate (PIP2)- and cholesterol-containing monolayers","volume":"48","author":"Levantal","year":"2009","journal-title":"Biochemistry"},{"key":"10.1016\/j.abb.2024.110045_bib55","unstructured":"National Center for Biotechnology Information. PubChem Compound Summary for CID 53408309, 5-Methylpyridin-3-amine dihydrochloride. https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/5-Methylpyridin-3-amine-dihydrochloride."},{"key":"10.1016\/j.abb.2024.110045_bib56","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jbior.2014.09.015","article-title":"Inositol pyrophosphates: why so many phosphates?","volume":"57","author":"Shears","year":"2015","journal-title":"Adv Biol Regul."},{"key":"10.1016\/j.abb.2024.110045_bib57","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jare.2017.11.004","article-title":"Arachidonic acid: physiological roles and potential health benefits - a review","volume":"11","author":"Tallima","year":"2017","journal-title":"J. Adv. Res."},{"issue":"3","key":"10.1016\/j.abb.2024.110045_bib58","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1042\/EBC20200041","article-title":"Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane","volume":"64","author":"Katan","year":"2020","journal-title":"Essays Biochem."},{"issue":"40","key":"10.1016\/j.abb.2024.110045_bib59","doi-asserted-by":"crossref","first-page":"9360","DOI":"10.1021\/bi9008616","article-title":"Ionization properties of phosphatidylinositol polyphosphates in mixed model membranes","volume":"48","author":"Kooijman","year":"2009","journal-title":"Biochemistry"},{"key":"10.1016\/j.abb.2024.110045_bib60","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1002\/1873-3468.13186","article-title":"Roles of PIP2 in the membrane binding of MIM I-BAR: insights from molecular dynamics simulations","volume":"592","author":"Lin","year":"2018","journal-title":"FEBS Lett."},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib61","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4161\/bioa.28809","article-title":"Why does endocytosis in single cells care which side up?","volume":"4","author":"Schauer","year":"2014","journal-title":"BioArchitecture"},{"issue":"7","key":"10.1016\/j.abb.2024.110045_bib62","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1021\/acs.jpcb.9b10951","article-title":"Characterization of specific ion effects on PI94,5)P2 clustering: molecular dynamics simulations and graph-theoretic analysis","volume":"124","author":"Han","year":"2020","journal-title":"J. Phys. Chem. B"},{"issue":"6","key":"10.1016\/j.abb.2024.110045_bib63","doi-asserted-by":"crossref","first-page":"F1761","DOI":"10.1152\/ajprenal.00400.2007","article-title":"Complex roles of PIP2 in the regulation of ion channels and transporters","volume":"293","author":"Huang","year":"2007","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.abb.2024.110045_bib64","doi-asserted-by":"crossref","unstructured":"Zaydman MA, Silva JR, Delaloye K, Li Y, Liang H, Larsson HP, Shi J, Cui J. Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening. Proceedings of the National Academy of Sciences; 13180-13185 110 32. Doi: 10.1073\/pnas.1305167110.","DOI":"10.1073\/pnas.1305167110"},{"key":"10.1016\/j.abb.2024.110045_bib65","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1113\/jphysiol.2007.132498","article-title":"Regulation of M(Kv7.2\/7.3) channels in neurons by PIP2 and products of PIP2 hydrolysis: significance for receptor-mediated inhibition","volume":"582","author":"Brown","year":"2007","journal-title":"J. Physiol."},{"issue":"7","key":"10.1016\/j.abb.2024.110045_bib66","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/nchembio.2372","article-title":"Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells","volume":"13","author":"Rosholm","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.abb.2024.110045_bib67","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.73901","article-title":"Allosteric modulation of the adenosine A2A receptor by cholesterol","volume":"11","author":"Huang","year":"2022","journal-title":"Elife"},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib68","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1038\/s41467-019-10108-0","article-title":"Local membrane charge regulates \u03b22 adrenergic receptor coupling to Gi3","volume":"10","author":"Strohman","year":"2019","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib69","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nchembio.1960","article-title":"Allosteric regulation of G protein-coupled receptor activity by phospholipids","volume":"12","author":"Dawaliby","year":"2016","journal-title":"Nat. Chem. Biol."},{"issue":"4","key":"10.1016\/j.abb.2024.110045_bib70","doi-asserted-by":"crossref","first-page":"2524","DOI":"10.1007\/s12035-018-1244-0","article-title":"Anionic phospholipids bind to and modulate the activity of human TRESK background K+ channel","volume":"56","author":"Giblin","year":"2019","journal-title":"Mol. Neurobiol."},{"issue":"7714","key":"10.1016\/j.abb.2024.110045_bib71","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/s41586-018-0325-6","article-title":"PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling","volume":"559","author":"Yen","year":"2018","journal-title":"Nature"},{"issue":"7854","key":"10.1016\/j.abb.2024.110045_bib72","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/s41586-021-03376-8","article-title":"Structural insights into the lipid and ligand regulation of serotonin receptors","volume":"592","author":"Xu","year":"2021","journal-title":"Nature"},{"issue":"7614","key":"10.1016\/j.abb.2024.110045_bib73","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/nature18966","article-title":"Structure of the adenosine A(2A) receptor bound to an engineered G protein [published correction appears in Nature. 2016 Oct 27;538(7626):542]","volume":"536","author":"Carpenter","year":"2016","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib74","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.str.2018.10.024","article-title":"State-dependent lipid interactions with the A2a receptor revealed by MD simulations using in vivo-mimetic membranes","volume":"27","author":"Song","year":"2019","journal-title":"Structure"},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib75","first-page":"139","article-title":"GPCR dynamics: structures in motion","volume":"117","author":"Latorraca","year":"2016","journal-title":"Chem. Rev. 2017"},{"issue":"20","key":"10.1016\/j.abb.2024.110045_bib76","doi-asserted-by":"crossref","first-page":"4729","DOI":"10.3390\/molecules25204729","article-title":"Structure and dynamics of GPCRs in lipid membranes: physical principles and experimental approaches","volume":"25","author":"Jones","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.abb.2024.110045_bib77","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/s41467-023-36425-z","article-title":"Anionic phospholipids control mechanisms of GPCR-G protein recognition","volume":"14","author":"Thakur","year":"2023","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib78","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4097\/kja.22654","article-title":"Mechanisms and implications in gene polymorphism mediated diverse responses to sedatives, analgesics and muscle relaxants","volume":"76","author":"Sun","year":"2023","journal-title":"Korean J Anesthesiol"},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib79","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.bjae.2019.10.002","article-title":"Basic pharmacology of local anaesthetics [published correction appears in BJA Educ. 2020 Apr;20(4):140]","volume":"20","author":"Taylor","year":"2020","journal-title":"BJA Educ"},{"issue":"3","key":"10.1016\/j.abb.2024.110045_bib80","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/0005-2760(92)90008-J","article-title":"Resistance to ethanol disordering of membranes from ethanol-fed rats is conferred by all phospholipid classes","volume":"1123","author":"Rottenberg","year":"1992","journal-title":"Biochim. Biophys. Acta Lipids Lipid. Metabol."},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib81","first-page":"267","article-title":"Altered phospholipid composition in mutants of Escherichia coli sensitive or resistant to organic solvents","volume":"113","author":"Clark","year":"1979","journal-title":"Microbiology"},{"issue":"9","key":"10.1016\/j.abb.2024.110045_bib82","doi-asserted-by":"crossref","first-page":"226","DOI":"10.3390\/membranes10090226","article-title":"The role of lipid environment in ganglioside GM1-induced amyloid \u03b2 aggregation","volume":"10","author":"Rudajev","year":"2020","journal-title":"Membranes"},{"issue":"Pt 17","key":"10.1016\/j.abb.2024.110045_bib83","doi-asserted-by":"crossref","first-page":"3169","DOI":"10.1113\/jphysiol.2010.191585","article-title":"Lipid microdomains and the regulation of ion channel function","volume":"588","author":"Dart","year":"2010","journal-title":"J. Physiol."},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib84","first-page":"123","article-title":"Mechanism of action of volatile anesthetics: involvement of intracellular calcium signaling","volume":"2","author":"Gomez","year":"2003","journal-title":"Curr. Drug Targets: CNS Neurol. Disord."},{"key":"10.1016\/j.abb.2024.110045_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2020.113826","article-title":"Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3)","volume":"174","author":"Kelemen","year":"2020","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.abb.2024.110045_bib86","doi-asserted-by":"crossref","first-page":"12 3109","DOI":"10.1073\/pnas.1611717114","article-title":"Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties","volume":"114","author":"Herold","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"16","key":"10.1016\/j.abb.2024.110045_bib87","doi-asserted-by":"crossref","first-page":"5206","DOI":"10.1074\/jbc.REV119.007061","article-title":"Heterotrimeric Gq proteins as therapeutic targets?","volume":"295","author":"Kostenis","year":"2020","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.abb.2024.110045_bib88","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.3390\/jcm10061306","article-title":"Inhaled anesthetics: environmental role, occupational risk, and clinical use","volume":"10","author":"Gaya da Costa","year":"2021","journal-title":"J. Clin. Med."},{"issue":"2\u20133","key":"10.1016\/j.abb.2024.110045_bib89","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0014-2999(97)01354-X","article-title":"Inhibitory effects of anesthetics and ethanol on muscarinic receptors expressed in Xenopus oocytes","volume":"339","author":"Minami","year":"1997","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.abb.2024.110045_bib90","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.tibs.2009.10.002","article-title":"GSK3: a multifaceted kinase in Wnt signaling","volume":"35","author":"Wu","year":"2010","journal-title":"Trends Biochem. Sci."},{"issue":"12","key":"10.1016\/j.abb.2024.110045_bib91","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1038\/emboj.2012.150","article-title":"The many faces and functions of \u03b2-catenin","volume":"31","author":"Valenta","year":"2012","journal-title":"EMBO J."},{"issue":"16","key":"10.1016\/j.abb.2024.110045_bib92","doi-asserted-by":"crossref","first-page":"8502","DOI":"10.3390\/ijms22168502","article-title":"TRPM8 channels: advances in structural studies and pharmacological modulation","volume":"22","author":"Izquierdo","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.abb.2024.110045_bib93","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/sj.emboj.7600118","article-title":"Modulation of kinesin binding by the C-termini of tubulin","volume":"23","author":"Skiniotis","year":"2004","journal-title":"EMBO J."},{"issue":"6","key":"10.1016\/j.abb.2024.110045_bib94","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.molcel.2020.10.027","article-title":"Heterotrimeric G protein subunit G\u03b1q is a master switch for g\u03b2\u03b3-mediated calcium mobilization by gi-coupled GPCRs","volume":"80","author":"Pfeil","year":"2020","journal-title":"Mol. Cell."},{"issue":"4","key":"10.1016\/j.abb.2024.110045_bib95","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1097\/00000542-199904000-00029","article-title":"Volatile anesthetics increase intracellular calcium in cerebrocortical and hippocampal neurons","volume":"90","author":"Kindler","year":"1999","journal-title":"Anesthesiology"},{"issue":"39","key":"10.1016\/j.abb.2024.110045_bib96","doi-asserted-by":"crossref","first-page":"9983","DOI":"10.1523\/JNEUROSCI.2773-06.2006","article-title":"Modulation of Gq-protein-coupled inositol trisphosphate and Ca2+ signaling by the membrane potential","volume":"26","author":"Billups","year":"2006","journal-title":"J. Neurosci."},{"issue":"12","key":"10.1016\/j.abb.2024.110045_bib97","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.2174\/0929866528666211027113349","article-title":"Wogonin and alleviation of hyperglycemia via inhibition of dag mediated PKC expression. A brief insight","volume":"28","author":"Khan","year":"2021","journal-title":"Protein Pept. Lett."},{"issue":"5","key":"10.1016\/j.abb.2024.110045_bib98","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/S0896-6273(00)80125-7","article-title":"Muscarinic modulation of sodium current by activation of protein kinase C in rat hippocampal neurons","volume":"16","author":"Cantrell","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.abb.2024.110045_bib99","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/978-3-030-12457-1_9","article-title":"Phospholipase C","volume":"1131","author":"Bill","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib100","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1093\/bja\/aef160","article-title":"Anaesthetic actions on other targets: protein kinase C and guanine nucleotide-binding proteins","volume":"89","author":"Rebecchi","year":"2002","journal-title":"Br. J. Anaesth."},{"issue":"23","key":"10.1016\/j.abb.2024.110045_bib101","doi-asserted-by":"crossref","first-page":"6025","DOI":"10.1111\/j.1742-4658.2007.06116.x","article-title":"G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis","volume":"274","author":"New","year":"2007","journal-title":"FEBS J."},{"issue":"15","key":"10.1016\/j.abb.2024.110045_bib102","doi-asserted-by":"crossref","first-page":"10742","DOI":"10.1074\/jbc.R112.411645","article-title":"Calcium channels and short-term synaptic plasticity","volume":"288","author":"Catterall","year":"2013","journal-title":"J. Biol. Chem."},{"issue":"8","key":"10.1016\/j.abb.2024.110045_bib103","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a003947","article-title":"Voltage-gated calcium channels","volume":"3","author":"Catterall","year":"2011","journal-title":"Cold Spring Harbor Perspect. Biol."},{"issue":"10","key":"10.1016\/j.abb.2024.110045_bib104","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s40263-017-0463-7","article-title":"The role of GABA receptor agonists in anesthesia and sedation","volume":"31","author":"Brohan","year":"2017","journal-title":"CNS Drugs"},{"key":"10.1016\/j.abb.2024.110045_bib105","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.78929","article-title":"Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation","volume":"11","author":"K\u00fcey","year":"2022","journal-title":"Elife"},{"issue":"2","key":"10.1016\/j.abb.2024.110045_bib106","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamem.2020.183511","article-title":"Membrane nanodomains homeostasis during propofol anesthesia as function of dosage and temperature","volume":"1863","author":"Jin","year":"2021","journal-title":"Biochim. Biophys. Acta Biomembr."},{"issue":"3","key":"10.1016\/j.abb.2024.110045_bib107","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1124\/jpet.122.001337","article-title":"Competitive interactions between propofol and diazepam: studies in GABAA receptors and zebrafish","volume":"383","author":"Pence","year":"2022","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.abb.2024.110045_bib108","unstructured":"Vanlersberghe C, Camu F. Propofol. Handbook of Experimental Pharmacology Book Series Volume vol. 182."},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib109","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1038\/s41467-023-37463-3","article-title":"Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiology","volume":"14","author":"Tian","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.abb.2024.110045_bib110","doi-asserted-by":"crossref","DOI":"10.1038\/srep22718","article-title":"Light-evoked hyperpolarization and silencing of neurons by conjugated polymers","volume":"6","author":"Feyen","year":"2016","journal-title":"Sci. Rep."},{"issue":"27","key":"10.1016\/j.abb.2024.110045_bib111","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1056\/NEJMra0808281","article-title":"General anesthesia, sleep, and coma","volume":"363","author":"Brown","year":"2010","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib112","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1186\/s13287-022-03087-5","article-title":"Propofol enhances stem-like properties of glioma via GABAAR-dependent Src modulation of ZDHHC5-EZH2 palmitoylation mechanism","volume":"13","author":"Fan","year":"2022","journal-title":"Stem Cell Res. Ther."},{"issue":"12","key":"10.1016\/j.abb.2024.110045_bib113","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.3390\/cells8121619","article-title":"TGF-\u0392 and microRNA interplay in genitourinary cancers","volume":"8","author":"Boguslawska","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.abb.2024.110045_bib114","article-title":"Propofol inhibits cell proliferation, migration, and invasion via mir-410-3p\/transforming growth factor-\u03b2 receptor type 2 (TGFBR2) Axis in glioma","volume":"26","author":"Li","year":"2020","journal-title":"Med. Sci. Mon. Int. Med. J. Exp. Clin. Res."},{"issue":"6","key":"10.1016\/j.abb.2024.110045_bib115","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.bbalip.2014.09.010","article-title":"Phosphoinositides regulate ion channels","volume":"1851","author":"Hille","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"issue":"17","key":"10.1016\/j.abb.2024.110045_bib116","doi-asserted-by":"crossref","first-page":"3493","DOI":"10.1007\/s00213-014-3486-5","article-title":"Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function","volume":"231","author":"Mennerick","year":"2014","journal-title":"Psychopharmacology"},{"issue":"1","key":"10.1016\/j.abb.2024.110045_bib117","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s43141-021-00224-0","article-title":"GABAA receptors: structure, function, pharmacology, and related disorders","volume":"19","author":"Ghit","year":"2021","journal-title":"J. Genet. Eng. Biotechnol."},{"key":"10.1016\/j.abb.2024.110045_bib118","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/s41586-018-0833-4","article-title":"Cryo-EM structure of the human \u03b11\u03b23\u03b32 GABAA receptor in a lipid bilayer","volume":"565","author":"Laverty","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.abb.2024.110045_bib119","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ejphar.2015.06.052","article-title":"Propofol depresses cerebellar Purkinje cell activity via activation of GABA(A) and glycine receptors in vivo in mice","volume":"764","author":"Jin","year":"2015","journal-title":"Eur. J. Pharmacol."}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986124001668?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986124001668?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T22:03:16Z","timestamp":1718229796000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986124001668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":119,"alternative-id":["S0003986124001668"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2024.110045","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The impact of volatile anesthetics and propofol on phosphatidylinositol 4,5-bisphosphate signaling","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2024.110045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"110045"}}