{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:23:02Z","timestamp":1789093382024,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004572","name":"National Health and Family Planning Commission of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010451","name":"Health and Family Planning Commission of Hunan Province","doi-asserted-by":"publisher","award":["B202310007057"],"award-info":[{"award-number":["B202310007057"]}],"id":[{"id":"10.13039\/501100010451","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Hunan Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2023JJ40867"],"award-info":[{"award-number":["2023JJ40867"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.abb.2025.110385","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T12:06:53Z","timestamp":1741781213000},"page":"110385","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["PANoptosis-related gene biomarkers in aortic dissection"],"prefix":"10.1016","volume":"768","author":[{"given":"Yuting","family":"Pu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuo","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangping","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guifang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"41","key":"10.1016\/j.abb.2025.110385_bib1","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1093\/eurheartj\/ehu281","volume":"35","author":"Erbel","year":"2014","journal-title":"Eur. Heart J."},{"issue":"10","key":"10.1016\/j.abb.2025.110385_bib2","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/eurheartj\/ehac757","article-title":"Acute aortic dissection: evidence, uncertainties, and future therapies","volume":"44","author":"Rylski","year":"2023","journal-title":"Eur. Heart J."},{"issue":"1","key":"10.1016\/j.abb.2025.110385_bib3","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/0735-1097(90)90458-2","article-title":"Cystic medial necrosis of the aorta in patients without Marfan's syndrome: surgical outcome and long-term follow-up","volume":"16","author":"Marsalese","year":"1990","journal-title":"J. Am. Coll. Cardiol."},{"issue":"26","key":"10.1016\/j.abb.2025.110385_bib4","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1093\/eurheartj\/ehaa352","article-title":"Prevention of aortic dissection and aneurysm via an ALDH2-mediated switch in vascular smooth muscle cell phenotype","volume":"41","author":"Yang","year":"2020","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.abb.2025.110385_bib5","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.yjmcc.2024.02.006","article-title":"Cannabidiol protects against acute aortic dissection by inhibiting macrophage infiltration and PMAIP1-induced vascular smooth muscle cell apoptosis","volume":"189","author":"Guo","year":"2024","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.abb.2025.110385_bib6","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.675647","article-title":"Sirt3 protects against thoracic aortic dissection formation by reducing reactive oxygen species, vascular inflammation, and apoptosis of smooth muscle cells","volume":"8","author":"Qiu","year":"2021","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.abb.2025.110385_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.117882","article-title":"Role of c-Abl in Ang II-induced aortic dissection formation: potential regulatory efficacy on phenotypic transformation and apoptosis of VSMCs","volume":"256","author":"Zhou","year":"2020","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.abb.2025.110385_bib8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1097\/FJC.0000000000000835","article-title":"Long noncoding RNA XIST\/miR-17\/PTEN Axis modulates the proliferation and apoptosis of vascular smooth muscle cells to affect stanford type A aortic dissection","volume":"76","author":"Zhang","year":"2020","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"1","key":"10.1016\/j.abb.2025.110385_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.23028","article-title":"Involvement of miR-145 in the development of aortic dissection via inducing proliferation, migration, and apoptosis of vascular smooth muscle cells","volume":"34","author":"Huang","year":"2020","journal-title":"J. Clin. Lab. Anal."},{"issue":"20","key":"10.1016\/j.abb.2025.110385_bib10","first-page":"4632","article-title":"YAP1 up-regulation inhibits apoptosis of aortic dissection vascular smooth muscle cells","volume":"21","author":"Liu","year":"2017","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"1","key":"10.1016\/j.abb.2025.110385_bib11","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/imr.13279","article-title":"PANoptosis: mechanisms, biology, and role in disease","volume":"321","author":"Sun","year":"2024","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.abb.2025.110385_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2022.109019","article-title":"Characterization of PANoptosis patterns predicts survival and immunotherapy response in gastric cancer","volume":"238","author":"Pan","year":"2022","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.abb.2025.110385_bib13","doi-asserted-by":"crossref","first-page":"406","DOI":"10.3389\/fcimb.2019.00406","article-title":"ZBP1 and TAK1: master regulators of NLRP3 inflammasome\/pyroptosis, apoptosis, and necroptosis (PAN-optosis)","volume":"9","author":"Malireddi","year":"2019","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"13","key":"10.1016\/j.abb.2025.110385_bib14","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1016\/j.cell.2023.05.005","article-title":"NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs","volume":"186","author":"Sundaram","year":"2023","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.abb.2025.110385_bib15","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20191644","article-title":"Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease","volume":"217","author":"Malireddi","year":"2020","journal-title":"J. Exp. Med."},{"issue":"7876","key":"10.1016\/j.abb.2025.110385_bib16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/s41586-021-03875-8","article-title":"AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence","volume":"597","author":"Lee","year":"2021","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.abb.2025.110385_bib17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/imr.12909","article-title":"The regulation of the ZBP1-NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis)","volume":"297","author":"Zheng","year":"2020","journal-title":"Immunol. Rev."},{"issue":"2","key":"10.1016\/j.abb.2025.110385_bib18","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aag2045","article-title":"ZBP1\/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways","volume":"1","author":"Kuriakose","year":"2016","journal-title":"Sci Immunol"},{"issue":"15","key":"10.1016\/j.abb.2025.110385_bib19","doi-asserted-by":"crossref","first-page":"4061","DOI":"10.1016\/j.cell.2024.05.034","article-title":"NLRC5 senses NAD(+) depletion, forming a PANoptosome and driving PANoptosis and inflammation","volume":"187","author":"Sundaram","year":"2024","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.abb.2025.110385_bib20","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.immuni.2024.03.012","article-title":"The NLR family of innate immune and cell death sensors","volume":"57","author":"Sundaram","year":"2024","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.abb.2025.110385_bib21","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.tips.2024.06.002","article-title":"PANoptosis: a novel target for cardiovascular diseases","volume":"45","author":"Xiang","year":"2024","journal-title":"Trends Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.abb.2025.110385_bib22","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1152\/physiolgenomics.00053.2023","article-title":"PANoptosis in vascular smooth muscle cells regulated by TNF-\u03b1\/IL-1\u03b2 can be a new target for alleviating the progression of abdominal aortic aneurysm","volume":"56","author":"Li","year":"2024","journal-title":"Physiol. Genom."},{"issue":"6","key":"10.1016\/j.abb.2025.110385_bib23","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s00011-024-01877-6","article-title":"Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis","volume":"73","author":"Zheng","year":"2024","journal-title":"Inflamm. Res."},{"issue":"W1","key":"10.1016\/j.abb.2025.110385_bib24","doi-asserted-by":"crossref","first-page":"W212","DOI":"10.1093\/nar\/gkz446","article-title":"ChEA3: transcription factor enrichment analysis by orthogonal omics integration","volume":"47","author":"Keenan","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"21","key":"10.1016\/j.abb.2025.110385_bib25","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1161\/CIRCULATIONAHA.121.057623","article-title":"Nuclear receptor NR1D1 regulates abdominal aortic aneurysm development by targeting the mitochondrial tricarboxylic acid cycle enzyme aconitase-2","volume":"146","author":"Sun","year":"2022","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.abb.2025.110385_bib26","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.bbrc.2008.05.122","article-title":"GADD45B inhibits MKK7-induced cardiac hypertrophy and the polymorphisms of GADD45B is associated with inter-ventricular septum hypertrophy","volume":"372","author":"Wang","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.abb.2025.110385_bib27","doi-asserted-by":"crossref","first-page":"9976","DOI":"10.1080\/21655979.2021.1988840","article-title":"Role of ferroptosis-related genes in Stanford type a aortic dissection and identification of key genes: new insights from bioinformatic analysis","volume":"12","author":"Zou","year":"2021","journal-title":"Bioengineered"},{"key":"10.1016\/j.abb.2025.110385_bib28","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/3918393","article-title":"The effect of N6-methyladenosine regulators and m6A reader YTHDC1-mediated N6-methyladenosine modification is involved in oxidative stress in human aortic dissection","volume":"2023","author":"Yin","year":"2023","journal-title":"Oxid. Med. Cell. Longev."}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986125000980?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986125000980?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T13:08:20Z","timestamp":1762088900000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986125000980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":28,"alternative-id":["S0003986125000980"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2025.110385","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PANoptosis-related gene biomarkers in aortic dissection","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2025.110385","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110385"}}