{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:37:44Z","timestamp":1793831864190,"version":"4.6.1"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["310131\/2023-5"],"award-info":[{"award-number":["310131\/2023-5"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008223","name":"Universidade Federal do Paran\u00e1","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008223","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004779","name":"Pontificia Universidade Cat\u00f3lica do Paran\u00e1","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004612","name":"Araucaria Foundation","doi-asserted-by":"publisher","award":["PBA2022011000189"],"award-info":[{"award-number":["PBA2022011000189"]}],"id":[{"id":"10.13039\/501100004612","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.abb.2026.110830","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:58:09Z","timestamp":1777474689000},"page":"110830","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["SGLT2i combined with physical training attenuates metabolic dysfunction and pyroptosis-mediated renal cell death in diabetic kidney disease"],"prefix":"10.1016","volume":"782","author":[{"given":"Andr\u00e9 D.","family":"Lass","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo AB.","family":"Machado-J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateus T.","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia S.","family":"Pedroso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa C.","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamyres L.","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateus F.","family":"Zazula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katya","family":"Nailiko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo CL.","family":"Silveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samya H.","family":"Mehanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seigo","family":"Nagashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"de Noronha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thyago Proen\u00e7a","family":"de Moraes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo A.","family":"Pinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.abb.2026.110830_bib1","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1016\/j.mayocp.2022.05.003","article-title":"Diabetic kidney disease back in focus: management field guide for health care professionals in the 21st century","volume":"97","author":"Alicic","year":"2022","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.abb.2026.110830_bib2","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.18553\/jmcp.2020.26.12.1506","article-title":"Annual health care resource utilization and cost among type 2 diabetes patients with newly recognized chronic kidney disease within a large U.S. administrative claims database","volume":"26","author":"Folkerts","year":"2020","journal-title":"JMCP"},{"key":"10.1016\/j.abb.2026.110830_bib3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2337\/dc20-1913","article-title":"Worldwide epidemiology of diabetes-related end-stage renal disease, 2000\u20132015","volume":"44","author":"Cheng","year":"2021","journal-title":"Diabetes Care"},{"key":"10.1016\/j.abb.2026.110830_bib4","doi-asserted-by":"crossref","first-page":"227","DOI":"10.11613\/BM.2023.030501","article-title":"Diagnostic challenges of diabetic kidney disease","volume":"33","author":"Bo\u017ei\u010devi\u0107","year":"2023","journal-title":"Biochem. Med."},{"key":"10.1016\/j.abb.2026.110830_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.xkme.2024.100873","article-title":"Healthcare costs across diabetic kidney disease stages: a veterans affairs study","volume":"6","author":"Kim","year":"2024","journal-title":"Kidney Medicine"},{"key":"10.1016\/j.abb.2026.110830_bib6","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.2337\/dci23-0030","article-title":"Diabetic nephropathy: update on pillars of therapy slowing progression","volume":"46","author":"Naaman","year":"2023","journal-title":"Diabetes Care"},{"key":"10.1016\/j.abb.2026.110830_bib7","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.trsl.2023.11.002","article-title":"Current updates on metabolites and its interlinked pathways as biomarkers for diabetic kidney disease: a systematic review","volume":"265","author":"Das","year":"2024","journal-title":"Transl. Res."},{"key":"10.1016\/j.abb.2026.110830_bib8","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3390\/toxins13020142","article-title":"Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets","volume":"13","author":"Lim","year":"2021","journal-title":"Toxins"},{"key":"10.1016\/j.abb.2026.110830_bib9","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1007\/s00125-018-4654-7","article-title":"Development of SGLT1 and SGLT2 inhibitors","volume":"61","author":"Rieg","year":"2018","journal-title":"Diabetologia"},{"key":"10.1016\/j.abb.2026.110830_bib10","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3390\/jcdd9070225","article-title":"Sodium-glucose Cotransporter-2 inhibitors-from the treatment of diabetes to therapy of chronic heart failure","volume":"9","author":"Kurczy\u0144ski","year":"2022","journal-title":"JCDD"},{"key":"10.1016\/j.abb.2026.110830_bib11","doi-asserted-by":"crossref","DOI":"10.1590\/2175-8239-jbn-2023-0187en","article-title":"SGLT2 inhibitors and NLRP3 inflammasome: potential target in diabetic kidney disease","volume":"46","author":"Machado J\u00fanior","year":"2024","journal-title":"Braz. J. Nephrol."},{"key":"10.1016\/j.abb.2026.110830_bib12","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/s41581-024-00827-z","article-title":"Combination therapy for kidney disease in people with diabetes mellitus","volume":"20","author":"Van Raalte","year":"2024","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.abb.2026.110830_bib13","doi-asserted-by":"crossref","first-page":"ii3","DOI":"10.1093\/ckj\/sfab012","article-title":"Exercise training in chronic kidney disease\u2014effects, expectations and adherence","volume":"14","author":"Clyne","year":"2021","journal-title":"Clin. Kidney J."},{"key":"10.1016\/j.abb.2026.110830_bib14","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jshs.2023.06.005","article-title":"The influence of resistance exercise training prescription variables on skeletal muscle mass, strength, and physical function in healthy adults: an umbrella review","volume":"13","author":"Mcleod","year":"2024","journal-title":"J. Sport Health Sci."},{"key":"10.1016\/j.abb.2026.110830_bib15","doi-asserted-by":"crossref","DOI":"10.1136\/bmjsem-2016-000143","article-title":"Update on the effects of physical activity on insulin sensitivity in humans","volume":"2","author":"Bird","year":"2017","journal-title":"BMJ Open Sport Exerc Med"},{"key":"10.1016\/j.abb.2026.110830_bib16","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.3390\/nu14112179","article-title":"Resistance exercise training improves metabolic and inflammatory control in adipose and muscle tissues in mice fed a high-fat diet","volume":"14","author":"Effting","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.abb.2026.110830_bib17","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1177\/1535370220928986","article-title":"Influence of exercise training on diabetic kidney disease: a brief physiological approach","volume":"245","author":"Amaral","year":"2020","journal-title":"Exp. Biol. Med. (Maywood, NJ, U. S.)"},{"key":"10.1016\/j.abb.2026.110830_bib18","doi-asserted-by":"crossref","first-page":"3061","DOI":"10.12659\/MSM.913512","article-title":"Long-term intensive lifestyle intervention promotes improvement of stage III diabetic nephropathy","volume":"25","author":"Dong","year":"2019","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.abb.2026.110830_bib19","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.metabol.2019.05.009","article-title":"The combination of exercise training and sodium-glucose cotransporter-2 inhibition improves glucose tolerance and exercise capacity in a rodent model of type 2 diabetes","volume":"97","author":"Linden","year":"2019","journal-title":"Metabolism"},{"key":"10.1016\/j.abb.2026.110830_bib20","article-title":"Beneficial effects of sarpogrelate and rosuvastatin in high fat Diet\/streptozotocin-induced nephropathy in mice","volume":"11","author":"Kim","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.abb.2026.110830_bib21","first-page":"3587","article-title":"Revisiting experimental models of diabetic nephropathy","volume":"21","author":"Giralt-L\u00f3pez","year":"2020","journal-title":"Int. J. Math. Stat."},{"key":"10.1016\/j.abb.2026.110830_bib22","doi-asserted-by":"crossref","DOI":"10.1155\/2008\/704045","article-title":"The characterization of high\u2010fat diet and multiple low\u2010dose streptozotocin induced type 2 diabetes rat model","volume":"2008","author":"Zhang","year":"2008","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.abb.2026.110830_bib23","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-54224-9","article-title":"Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice","volume":"9","author":"Pennig","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.abb.2026.110830_bib24","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1093\/ndt\/gfk037","article-title":"What you should know about the work-up of a renal biopsy","volume":"21","author":"Amann","year":"2006","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.abb.2026.110830_bib25","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1681\/ASN.2006070798","article-title":"Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice","volume":"17","author":"Zhao","year":"2006","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.abb.2026.110830_bib26","first-page":"88","article-title":"Measurement of total malondialdehyde in plasma and tissues by high-performance liquid chromatography and thiobarbituric acid assay","volume":"11","author":"T\u00fck\u00f6zkan","year":"2006","journal-title":"F\u0131rat T\u0131p Dergisi"},{"key":"10.1016\/j.abb.2026.110830_bib27","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jchromb.2015.11.052","article-title":"A step-by-step protocol for assaying protein carbonylation in biological samples","volume":"1019","author":"Colombo","year":"2016","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.abb.2026.110830_bib28","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1021\/acsptsci.4c00552","article-title":"Sodium-Glucose Cotransporter-2 inhibitor improves renal injury by regulating the redox profile, inflammatory parameters, and pyroptosis in an experimental model of diabetic kidney disease","volume":"8","author":"Machado-Junior","year":"2025","journal-title":"ACS Pharmacol. Transl. Sci."},{"key":"10.1016\/j.abb.2026.110830_bib29","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1681\/ASN.2009070721","article-title":"Mouse models of diabetic nephropathy","volume":"20","author":"Brosius","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.abb.2026.110830_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/9416419","article-title":"Animal models of diabetes-associated renal injury","volume":"2020","author":"Noshahr","year":"2020","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.abb.2026.110830_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e27749","article-title":"Exercise training improves diabetic renal injury by reducing fetuin-A, oxidative stress and inflammation in type 2 diabetic rats","volume":"10","author":"Saberi","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.abb.2026.110830_bib32","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/s41467-025-55917-8","article-title":"Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice","volume":"16","author":"Geng","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.abb.2026.110830_bib33","doi-asserted-by":"crossref","first-page":"E492","DOI":"10.1152\/ajpendo.00401.2019","article-title":"Combined effect of canagliflozin and exercise training on high-fat diet-fed mice","volume":"318","author":"Tanaka","year":"2020","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.abb.2026.110830_bib34","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.3390\/biom13081170","article-title":"Physical exercise and appetite regulation: new insights","volume":"13","author":"Caruso","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.abb.2026.110830_bib35","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nrendo.2016.162","article-title":"Exercise-stimulated glucose uptake \u2014 regulation and implications for glycaemic control","volume":"13","author":"Sylow","year":"2017","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.abb.2026.110830_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajmo.2023.100031","article-title":"The importance of exercise for glycemic control in type 2 diabetes","volume":"9","author":"Syeda","year":"2023","journal-title":"American Journal of Medicine Open"},{"key":"10.1016\/j.abb.2026.110830_bib37","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.redox.2017.06.009","article-title":"The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats","volume":"13","author":"Steven","year":"2017","journal-title":"Redox Biol."},{"key":"10.1016\/j.abb.2026.110830_bib38","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1111\/jphp.12223","article-title":"Effects of sodium-glucose cotransporter 2 selective inhibitor ipragliflozin on hyperglycaemia, oxidative stress, inflammation and liver injury in streptozotocin-induced type 1 diabetic rats","volume":"66","author":"Tahara","year":"2014","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.abb.2026.110830_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.109080","article-title":"The impact of SGLT2 inhibitors on inflammation: a systematic review and meta-analysis of studies in rodents","volume":"111","author":"Theofilis","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.abb.2026.110830_bib40","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.ebiom.2018.09.048","article-title":"Impacts of diabetes and an SGLT2 inhibitor on the glomerular number and volume in db\/db mice, as estimated by synchrotron radiation Micro-CT at SPring-8","volume":"36","author":"Takiyama","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.abb.2026.110830_bib41","doi-asserted-by":"crossref","first-page":"F700","DOI":"10.1152\/ajprenal.90548.2008","article-title":"Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db\/db mice","volume":"296","author":"Ghosh","year":"2009","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.abb.2026.110830_bib42","doi-asserted-by":"crossref","first-page":"3815","DOI":"10.3390\/jcm12113815","article-title":"Sodium glucose Cotransporter-2 inhibitor empagliflozin increases antioxidative capacity and improves renal function in diabetic rats","volume":"12","author":"Yaribeygi","year":"2023","journal-title":"JCM"},{"key":"10.1016\/j.abb.2026.110830_bib43","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.3390\/jcm8111814","article-title":"The SGLT2 inhibitor empagliflozin ameliorates the inflammatory profile in type 2 diabetic patients and promotes an antioxidant response in leukocytes","volume":"8","author":"Iannantuoni","year":"2019","journal-title":"JCM"},{"key":"10.1016\/j.abb.2026.110830_bib44","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1055\/a-2234-1797","article-title":"Effects of SGLT2 inhibitors and DPP-4 inhibitors on advanced glycation end products","volume":"74","author":"Kusunoki","year":"2024","journal-title":"Drug Res."},{"key":"10.1016\/j.abb.2026.110830_bib45","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/s41581-024-00836-y","article-title":"Applications of SGLT2 inhibitors beyond glycaemic control","volume":"20","author":"O'Hara","year":"2024","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.abb.2026.110830_bib46","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.019995","article-title":"Effects of sodium\u2010glucose linked transporter 2 inhibition with ertugliflozin on mitochondrial function, energetics, and metabolic gene expression in the presence and absence of diabetes mellitus in mice","volume":"10","author":"Croteau","year":"2021","journal-title":"JAHA"},{"key":"10.1016\/j.abb.2026.110830_bib47","doi-asserted-by":"crossref","first-page":"F767","DOI":"10.1152\/ajprenal.00565.2018","article-title":"Empagliflozin attenuates diabetic tubulopathy by improving mitochondrial fragmentation and autophagy","volume":"317","author":"Lee","year":"2019","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.abb.2026.110830_bib48","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1161\/HYPERTENSIONAHA.122.19586","article-title":"SGLT2 inhibition via empagliflozin improves endothelial function and reduces mitochondrial oxidative stress: insights from frail hypertensive and diabetic patients","volume":"79","author":"Mone","year":"2022","journal-title":"Hypertension"},{"key":"10.1016\/j.abb.2026.110830_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112008","article-title":"Gasdermin D pore-forming activity is redox-sensitive","volume":"42","author":"Devant","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.abb.2026.110830_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2020.100924","article-title":"An overview of the non-canonical inflammasome","volume":"76","author":"Downs","year":"2020","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.abb.2026.110830_bib51","first-page":"143","article-title":"Effects of aerobic exercise on Nrf2\/GPX4\/Ferroptosis pathway in myocardial injury in high-fat diet mice","volume":"38","author":"Wang","year":"2022","journal-title":"Zhongguo Ying Yong Sheng Li Xue Za Zhi"},{"key":"10.1016\/j.abb.2026.110830_bib52","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.tcb.2023.02.007","article-title":"Gasdermins gone wild: new roles for GSDMs in regulating cellular homeostasis","volume":"33","author":"Weindel","year":"2023","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.abb.2026.110830_bib53","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1007\/s11064-024-04152-6","article-title":"Physical exercise-induced activation of NRF2 and BDNF as a promising strategy for ferroptosis regulation in parkinson's disease","volume":"49","author":"Thirupathi","year":"2024","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.abb.2026.110830_bib54","doi-asserted-by":"crossref","first-page":"577","DOI":"10.33549\/physiolres.935290","article-title":"Effects of life-long exercise on age-related inflammation, apoptosis, oxidative stress, ferroptosis markers, and NRF2\/KAEP 1\/Klotho pathway in rat kidneys","author":"Yuan","year":"2024","journal-title":"Physiol. Res."}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986126001013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986126001013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T17:43:46Z","timestamp":1783187026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986126001013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":54,"alternative-id":["S0003986126001013"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2026.110830","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SGLT2i combined with physical training attenuates metabolic dysfunction and pyroptosis-mediated renal cell death in diabetic kidney disease","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2026.110830","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"110830"}}