{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:34:09Z","timestamp":1793028849139,"version":"4.5.0"},"reference-count":154,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archives of Biochemistry and Biophysics"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.abb.2026.111029","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:50:37Z","timestamp":1792651837000},"page":"111029","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Anthocyanins and brain health in the context of obesity and Western-style diets"],"prefix":"10.1016","volume":"787","author":[{"given":"Imani","family":"Muhammad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Cremonini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7462-1641","authenticated-orcid":false,"given":"Patricia I.","family":"Oteiza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.abb.2026.111029_bib1","article-title":"One in eight people globally are obese, with rates in children increasing fourfold in three decades","volume":"384","author":"Taylor","year":"2024","journal-title":"Br. Med. J."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib2","article-title":"Critical correlation between obesity and cardiovascular diseases and recent advancements in obesity","volume":"16","author":"Pakhare","year":"2024","journal-title":"Cureus"},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib3","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/ijms25031882","article-title":"The role of obesity in type 2 diabetes mellitus-An overview","volume":"25","author":"Chandrasekaran","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib4","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1017\/S0029665117002014","article-title":"The relationship between obesity and cognitive health and decline","volume":"76","author":"Dye","year":"2017","journal-title":"Proc. Nutr. Soc."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib5","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.cnur.2021.07.010","article-title":"Obesity and psychiatric disorders","volume":"56","author":"Perry","year":"2021","journal-title":"Nurs. Clin. North Am."},{"issue":"5","key":"10.1016\/j.abb.2026.111029_bib6","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1053\/j.gastro.2012.01.034","article-title":"A high-fat diet is associated with endotoxemia that originates from the gut","volume":"142","author":"Pendyala","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.abb.2026.111029_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fnint.2022.798995","article-title":"The obese brain: mechanisms of systemic and local inflammation, and interventions to reverse the cognitive deficit","volume":"16","author":"Salas-Venegas","year":"2022","journal-title":"Front. Integr. Neurosci."},{"key":"10.1016\/j.abb.2026.111029_bib8","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3389\/fncel.2019.00509","article-title":"High-fat diet induces neuroinflammation and mitochondrial impairment in mice cerebral cortex and synaptic fraction","volume":"13","author":"Cavaliere","year":"2019","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.abb.2026.111029_bib9","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.neurobiolaging.2017.06.014","article-title":"High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory","volume":"58","author":"Spencer","year":"2017","journal-title":"Neurobiol. Aging"},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/metabo13010086","article-title":"Obesity-induced brain neuroinflammatory and mitochondrial changes","volume":"13","author":"Schmitt","year":"2023","journal-title":"Metabolites"},{"key":"10.1016\/j.abb.2026.111029_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.metop.2026.100444","article-title":"Obesity-induced cognitive impairment: underlying mechanisms and therapeutic prospects","volume":"29","author":"Liu","year":"2026","journal-title":"Metabol. Open"},{"issue":"16","key":"10.1016\/j.abb.2026.111029_bib12","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.181690","article-title":"Childhood obesity's effect on cognition and brain connectivity worsens with low family income","volume":"9","author":"Tomasi","year":"2024","journal-title":"JCI Insight"},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib13","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S1474-4422(17)30084-4","article-title":"Neurological consequences of obesity","volume":"16","author":"O'Brien","year":"2017","journal-title":"Lancet Neurol."},{"issue":"2","key":"10.1016\/j.abb.2026.111029_bib14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.7570\/jomes20107","article-title":"Association of circulating brain-derived neurotrophic factor with cognition among adult obese population","volume":"30","author":"Katuri","year":"2021","journal-title":"J. Obes. Metab. Syndr."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib15","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s12888-021-03059-8","article-title":"Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age","volume":"21","author":"Yuan","year":"2021","journal-title":"BMC Psychiatry"},{"issue":"2","key":"10.1016\/j.abb.2026.111029_bib16","doi-asserted-by":"crossref","first-page":"e220","DOI":"10.1212\/WNL.0000000000201367","article-title":"Association of obesity with cognitive decline in black and white Americans","volume":"100","author":"Quaye","year":"2023","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.abb.2026.111029_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci11080999","article-title":"Obesity and gray matter volume assessed by neuroimaging: a systematic review","volume":"11","author":"Fern\u00e1ndez-And\u00fajar","year":"2021","journal-title":"Brain Sci."},{"key":"10.1016\/j.abb.2026.111029_bib18","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2023.1294420","article-title":"The complex relationship between obesity and neurodegenerative diseases: an updated review","volume":"17","author":"Neto","year":"2023","journal-title":"Front. Cell. Neurosci."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib19","article-title":"The association between Brain-Derived Neurotrophic Factor (BDNF) protein level and body mass index","volume":"59","author":"Taha","year":"2022","journal-title":"Medicina (Kaunas)"},{"issue":"13","key":"10.1016\/j.abb.2026.111029_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25137006","article-title":"Metabolic endotoxemia: from the gut to neurodegeneration","volume":"25","author":"Chmielarz","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.abb.2026.111029_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2025.107615","article-title":"High-fat diet and neuroinflammation: the role of mitochondria","volume":"212","author":"Song","year":"2025","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib22","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s13668-024-00595-z","article-title":"The effect of anthocyanins on cognition: a systematic review and meta-analysis of randomized clinical trial studies in cognitively impaired and healthy adults","volume":"14","author":"Lorzadeh","year":"2025","journal-title":"Curr. Nutr. Rep."},{"key":"10.1016\/j.abb.2026.111029_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101269","article-title":"Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis","volume":"26","author":"Cremonini","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.abb.2026.111029_bib24","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.freeradbiomed.2022.06.006","article-title":"Cyanidin and delphinidin restore colon physiology in high fat diet-fed mice: involvement of TLR-4 and redox-regulated signaling","volume":"188","author":"Iglesias","year":"2022","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.abb.2026.111029_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116069","article-title":"Anthocyanins and their metabolites promote white adipose tissue beiging by regulating mitochondria thermogenesis and dynamics","volume":"222","author":"Cremonini","year":"2024","journal-title":"Biochem. Pharmacol."},{"issue":"10","key":"10.1016\/j.abb.2026.111029_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201600952","article-title":"Jaboticaba berry peel intake prevents insulin-resistance-induced tau phosphorylation in mice","volume":"61","author":"Batista \u00c2","year":"2017","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.abb.2026.111029_bib27","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jnutbio.2018.10.015","article-title":"Purple sweet potato color protects against high-fat diet-induced cognitive deficits through AMPK-mediated autophagy in mouse hippocampus","volume":"65","author":"Zhuang","year":"2019","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.abb.2026.111029_bib28","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.bbr.2018.11.025","article-title":"Purple sweet potato color improves hippocampal insulin resistance via down-regulating SOCS3 and galectin-3 in high-fat diet mice","volume":"359","author":"Qin","year":"2019","journal-title":"Behav. Brain Res."},{"issue":"15","key":"10.1016\/j.abb.2026.111029_bib29","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1111\/bph.15083","article-title":"Cyanidin-3-O-glucoside improves non-alcoholic fatty liver disease by promoting PINK1-mediated mitophagy in mice","volume":"177","author":"Li","year":"2020","journal-title":"Br. J. Pharmacol."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib30","doi-asserted-by":"crossref","first-page":"2752","DOI":"10.1016\/j.tjnut.2024.07.028","article-title":"Dietary anthocyanins mitigate high-fat diet-induced hippocampal inflammation in mice","volume":"154","author":"Muhammad","year":"2024","journal-title":"J. Nutr."},{"issue":"11","key":"10.1016\/j.abb.2026.111029_bib31","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.jnutbio.2015.05.008","article-title":"The impact of chronic blackberry intake on the neuroinflammatory status of rats fed a standard or high-fat diet","volume":"26","author":"Meireles","year":"2015","journal-title":"J. Nutr. Biochem."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib32","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1016\/j.tjnut.2025.06.023","article-title":"Postprandial responses to a high-fat meal: dependence of metabolic and genomic alterations on the magnitude of hypertriglyceridemia in healthy young adults","volume":"155","author":"Mostofinejad","year":"2025","journal-title":"J. Nutr."},{"issue":"7","key":"10.1016\/j.abb.2026.111029_bib33","doi-asserted-by":"crossref","first-page":"4581","DOI":"10.1080\/87559129.2022.2029479","article-title":"Anthocyanins and proanthocyanidins: chemical structures, food sources, bioactivities, and product development","volume":"39","author":"Qi","year":"2023","journal-title":"Food Rev. Int."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib34","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1079\/NRR2005116","article-title":"Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans","volume":"19","author":"Kay","year":"2006","journal-title":"Nutr. Res. Rev."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib35","doi-asserted-by":"crossref","DOI":"10.3390\/foods9010002","article-title":"A review of factors affecting anthocyanin aioavailability: possible implications for the inter-individual variability","volume":"9","author":"Eker","year":"2019","journal-title":"Foods"},{"issue":"22","key":"10.1016\/j.abb.2026.111029_bib36","doi-asserted-by":"crossref","first-page":"5953","DOI":"10.1080\/10408398.2022.2026291","article-title":"Current knowledge of anthocyanin metabolism in the digestive tract: absorption, distribution, degradation, and interconversion","volume":"63","author":"Gui","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.abb.2026.111029_bib37","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev-food-030216-025636","article-title":"Anthocyanins and flavanones are more bioavailable than previously perceived: a review of recent evidence","volume":"8","author":"Kay","year":"2017","journal-title":"Annu. Rev. Food Sci. Technol."},{"key":"10.1016\/j.abb.2026.111029_bib38","unstructured":"G.T. Sigurdson, M.M. Giusti, The Stability and Absorption of Anthocyanins in the Mouth. , Food Chemistry, Function and Analysis, Royal Society of Chemistry: London, UK, 22019."},{"issue":"12","key":"10.1016\/j.abb.2026.111029_bib39","doi-asserted-by":"crossref","first-page":"4178","DOI":"10.1093\/jn\/133.12.4178","article-title":"Anthocyanins are efficiently absorbed from the stomach in anesthetized rats","volume":"133","author":"Talav\u00e9ra","year":"2003","journal-title":"J. Nutr."},{"issue":"1\u20133","key":"10.1016\/j.abb.2026.111029_bib40","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0014-5793(03)00504-0","article-title":"The stomach as a site for anthocyanins absorption from food","volume":"544","author":"Passamonti","year":"2003","journal-title":"FEBS Lett."},{"issue":"35","key":"10.1016\/j.abb.2026.111029_bib41","doi-asserted-by":"crossref","first-page":"7685","DOI":"10.1021\/acs.jafc.5b00412","article-title":"Experimental and theoretical data on the mechanism by which red wine anthocyanins are transported through a Human MKN-28 gastric cell model","volume":"63","author":"Oliveira","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.abb.2026.111029_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.126398","article-title":"In vitro gastrointestinal absorption of red wine anthocyanins - impact of structural complexity and phase II metabolization","volume":"317","author":"Han","year":"2020","journal-title":"Food Chem."},{"issue":"18","key":"10.1016\/j.abb.2026.111029_bib43","doi-asserted-by":"crossref","first-page":"3904","DOI":"10.1021\/jf405356b","article-title":"Some anthocyanins could be efficiently absorbed across the gastrointestinal mucosa: extensive presystemic metabolism reduces apparent bioavailability","volume":"62","author":"Fang","year":"2014","journal-title":"J. Agric. Food Chem."},{"issue":"8","key":"10.1016\/j.abb.2026.111029_bib44","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1039\/b802662a","article-title":"Dietary phenolics: chemistry, bioavailability and effects on health","volume":"26","author":"Crozier","year":"2009","journal-title":"Nat. Prod. Rep."},{"issue":"21","key":"10.1016\/j.abb.2026.111029_bib45","doi-asserted-by":"crossref","first-page":"7563","DOI":"10.1080\/10408398.2023.2187212","article-title":"Anthocyanins-gut microbiota-health axis: a review","volume":"64","author":"Liang","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib46","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1124\/dmd.111.039651","article-title":"Colonic catabolism of ellagitannins, ellagic acid, and raspberry anthocyanins: in vivo and in vitro studies","volume":"39","author":"Gonz\u00e1lez-Barrio","year":"2011","journal-title":"Drug Metab. Dispos."},{"issue":"19","key":"10.1016\/j.abb.2026.111029_bib47","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202300036","article-title":"Spontaneous and microbiota-driven degradation of anthocyanins in an in vitro human colon model","volume":"67","author":"Shehata","year":"2023","journal-title":"Mol. Nutr. Food Res."},{"issue":"13","key":"10.1016\/j.abb.2026.111029_bib48","doi-asserted-by":"crossref","first-page":"3268","DOI":"10.1111\/bph.12676","article-title":"The pharmacokinetics of anthocyanins and their metabolites in humans","volume":"171","author":"de Ferrars","year":"2014","journal-title":"Br. J. Pharmacol."},{"issue":"15","key":"10.1016\/j.abb.2026.111029_bib49","doi-asserted-by":"crossref","first-page":"3882","DOI":"10.1021\/jf3002153","article-title":"Metabolism of anthocyanins by human gut microflora and their influence on gut bacterial growth","volume":"60","author":"Hidalgo","year":"2012","journal-title":"J. Agric. Food Chem."},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib50","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00394-004-0502-2","article-title":"In vitro metabolism of anthocyanins by human gut microflora","volume":"44","author":"Aura","year":"2005","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.abb.2026.111029_bib51","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.foodchem.2017.06.054","article-title":"Biotransformation and metabolism of three mulberry anthocyanin monomers by rat gut microflora","volume":"237","author":"Chen","year":"2017","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib52","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00394-005-0557-8","article-title":"Stability and biotransformation of various dietary anthocyanins in vitro","volume":"45","author":"Fleschhut","year":"2006","journal-title":"Eur. J. Nutr."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib53","doi-asserted-by":"crossref","first-page":"21555","DOI":"10.3390\/ijms160921555","article-title":"Anthocyanin absorption and metabolism by human intestinal Caco-2 cells--A review","volume":"16","author":"Kamiloglu","year":"2015","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/srep22815","article-title":"Determination of cyanidin 3-glucoside in rat brain, liver and kidneys by UPLC\/MS-MS and its application to a short-term pharmacokinetic study","volume":"6","author":"Fornasaro","year":"2016","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib55","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1021\/jf071998l","article-title":"Identification of anthocyanins in the liver, eye, and brain of blueberry-fed pigs","volume":"56","author":"Kalt","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.abb.2026.111029_bib56","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.freeradbiomed.2015.10.400","article-title":"New insights into the bioavailability of red raspberry anthocyanins and ellagitannins","volume":"89","author":"Ludwig","year":"2015","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.abb.2026.111029_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102273","article-title":"A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy subjects","volume":"51","author":"Cremonini","year":"2022","journal-title":"Redox Biol."},{"issue":"5","key":"10.1016\/j.abb.2026.111029_bib58","doi-asserted-by":"crossref","first-page":"995","DOI":"10.3945\/ajcn.112.049247","article-title":"Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a (13)C-tracer study","volume":"97","author":"Czank","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.abb.2026.111029_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2024.105900","article-title":"An overview of the relationship between inflammation and cognitive function in humans, molecular pathways and the impact of nutraceuticals","volume":"181","author":"Mekhora","year":"2024","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.abb.2026.111029_bib60","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fendo.2020.00059","article-title":"Glucocorticoid metabolism in obesity and following weight loss","volume":"11","author":"Akalestou","year":"2020","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.abb.2026.111029_bib61","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3389\/fnut.2018.00131","article-title":"Effect of hypoproteic and high-fat diets on hippocampal blood-brain barrier permeability and oxidative stress","volume":"5","author":"de Aquino","year":"2018","journal-title":"Front. Nutr."},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib62","first-page":"4823","article-title":"Purple sweet potato color attenuates high fat-induced neuroinflammation in mouse brain by inhibiting MAPK and NF-\u03baB activation","volume":"17","author":"Li","year":"2018","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.abb.2026.111029_bib63","doi-asserted-by":"crossref","DOI":"10.4014\/jmb.2601.01068","article-title":"Black currant extract protects against oxidative stress in SH-SY5Y cells and high-fat diet-induced cognitive impairment in C57BL\/6 mice","volume":"36","author":"Im","year":"2026","journal-title":"J. Microbiol. Biotechnol."},{"key":"10.1016\/j.abb.2026.111029_bib64","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.1006132","article-title":"Black soybean seed coat polyphenol ameliorates the abnormal feeding pattern induced by high-fat diet consumption","volume":"9","author":"Hironao","year":"2022","journal-title":"Front. Nutr."},{"issue":"14","key":"10.1016\/j.abb.2026.111029_bib65","doi-asserted-by":"crossref","DOI":"10.3390\/nu14142977","article-title":"Systematic review on the potential effect of berry intake in the cognitive functions of healthy people","volume":"14","author":"De Amicis","year":"2022","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib66","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1007\/s00394-015-1029-4","article-title":"Cognitive effects following acute wild blueberry supplementation in 7- to 10-year-old children","volume":"55","author":"Whyte","year":"2016","journal-title":"Eur. J. Nutr."},{"issue":"2","key":"10.1016\/j.abb.2026.111029_bib67","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.appet.2012.05.108","article-title":"The cognitive effects of acute blueberry anthocyanin interventions on 7\u20139 year old children","volume":"59","author":"Whyte","year":"2012","journal-title":"Appetite"},{"issue":"11","key":"10.1016\/j.abb.2026.111029_bib68","doi-asserted-by":"crossref","DOI":"10.3390\/nu11112685","article-title":"Flavonoid-rich mixed berries maintain and improve cognitive function over a 6 h period in young healthy adults","volume":"11","author":"Whyte","year":"2019","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib69","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.ajcnut.2023.03.017","article-title":"Wild blueberry (poly)phenols can improve vascular function and cognitive performance in healthy older individuals: a double-blind randomized controlled trial","volume":"117","author":"Wood","year":"2023","journal-title":"Am. J. Clin. Nutr."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib70","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-29744-5","article-title":"Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins","volume":"8","author":"Marques","year":"2018","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib71","doi-asserted-by":"crossref","DOI":"10.3390\/nu18040674","article-title":"Berry consumption and its role in the modulation of obesity and mild cognitive impairment","volume":"18","author":"Santos","year":"2026","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib72","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1007\/s00394-020-02336-8","article-title":"Improved metabolic function and cognitive performance in middle-aged adults following a single dose of wild blueberry","volume":"60","author":"Whyte","year":"2021","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.abb.2026.111029_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2022.101156","article-title":"Anthocyanin actions at the gastrointestinal tract: relevance to their health benefits","volume":"89","author":"Oteiza","year":"2023","journal-title":"Mol. Aspect. Med."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib74","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1194\/jlr.M800156-JLR200","article-title":"Chylomicrons promote intestinal absorption of lipopolysaccharides","volume":"50","author":"Ghoshal","year":"2009","journal-title":"J. Lipid Res."},{"issue":"8","key":"10.1016\/j.abb.2026.111029_bib75","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1039\/C7FO00625J","article-title":"Anthocyanins inhibit tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity","volume":"8","author":"Cremonini","year":"2017","journal-title":"Food Funct."},{"issue":"5","key":"10.1016\/j.abb.2026.111029_bib76","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1093\/ajcn\/86.5.1286","article-title":"A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation2","volume":"86","author":"Erridge","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.abb.2026.111029_bib77","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2023.1207751","article-title":"Effects of anthocyanin supplementation on blood lipid levels: a systematic review and meta-analysis","volume":"10","author":"Jang","year":"2023","journal-title":"Front. Nutr."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib78","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.bbi.2009.09.001","article-title":"Minimal penetration of lipopolysaccharide across the murine blood-brain barrier","volume":"24","author":"Banks","year":"2010","journal-title":"Brain Behav. Immun."},{"issue":"2","key":"10.1016\/j.abb.2026.111029_bib79","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24021640","article-title":"Ultrastructural remodeling of the blood-brain barrier and neurovascular unit by lipopolysaccharide-induced neuroinflammation","volume":"24","author":"Erickson","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"0","key":"10.1016\/j.abb.2026.111029_bib80","article-title":"Anthocyanins-rich purple potato extract prevents low-grade chronic inflammation-associated metabolic disorders","volume":"23","author":"Hua","year":"2023","journal-title":"J. Food Bioactive."},{"issue":"10","key":"10.1016\/j.abb.2026.111029_bib81","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1021\/jf050145v","article-title":"Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain","volume":"53","author":"Talav\u00e9ra","year":"2005","journal-title":"J. Agric. Food Chem."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib82","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1002\/fsn3.3923","article-title":"Anthocyanins from Lycium ruthenicum Murray attenuates high-fat diet-induced hypercholesterolemia in ApoE(-\/-) mice are related to the modulation of gut microbiota and the ratio of conjugated to unconjugated bile acids in fecal bile acid profile","volume":"12","author":"Zhang","year":"2024","journal-title":"Food Sci. Nutr."},{"issue":"8","key":"10.1016\/j.abb.2026.111029_bib83","article-title":"Lycium ruthenicum anthocyanins attenuate high-fat diet-induced colonic barrier dysfunction and inflammation in mice by modulating the gut microbiota","volume":"65","author":"Tian","year":"2021","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.abb.2026.111029_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2019.108952","article-title":"Effects of long-term intake of anthocyanins from Lycium ruthenicum Murray on the organism health and gut microbiota in vivo","volume":"130","author":"Peng","year":"2020","journal-title":"Food Res. Int."},{"issue":"7","key":"10.1016\/j.abb.2026.111029_bib85","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27072141","article-title":"Preventive effects of anthocyanins from Lyciumruthenicum Murray in high-fat diet-induced obese mice are related to the regulation of intestinal microbiota and inhibition of pancreatic lipase activity","volume":"27","author":"Li","year":"2022","journal-title":"Molecules"},{"issue":"20","key":"10.1016\/j.abb.2026.111029_bib86","doi-asserted-by":"crossref","DOI":"10.3390\/nu16203555","article-title":"A one-week elderberry juice intervention augments the fecal microbiota and suggests improvement in glucose tolerance and fat oxidation in a randomized controlled trial","volume":"16","author":"Teets","year":"2024","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib87","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.5114\/aoms.2015.56342","article-title":"Brain-derived neurotrophic factor and its clinical implications","volume":"11","author":"Bathina","year":"2015","journal-title":"Arch. Med. Sci."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib88","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9010257","article-title":"Regulation of BDNF-TrkB signaling and potential therapeutic strategies for Parkinson's disease","volume":"9","author":"Jin","year":"2020","journal-title":"J. Clin. Med."},{"issue":"17","key":"10.1016\/j.abb.2026.111029_bib153","doi-asserted-by":"crossref","first-page":"12619","DOI":"10.1074\/jbc.M700607200","article-title":"Brain-derived Neurotrophic Factor Regulates the Expression and Synaptic Delivery of\u03b1-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor Subunits in Hippocampal Neurons","volume":"282","author":"Caldeira","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.abb.2026.111029_bib154","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1083\/jcb.146.5.955","article-title":"Depolarization and Neurotrophins Converge on the Phosphatidylinositol 3-Kinase\u2013Akt Pathway to Synergistically Regulate Neuronal Survival","volume":"146","author":"Vaillant","year":"1999","journal-title":"J. Cell Biol."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib89","doi-asserted-by":"crossref","first-page":"84","DOI":"10.5498\/wjp.v6.i1.84","article-title":"Are the changes in the peripheral brain-derived neurotrophic factor levels due to platelet activation?","volume":"6","author":"Serra-Mill\u00e0s","year":"2016","journal-title":"World J. Psychiatr."},{"issue":"12","key":"10.1016\/j.abb.2026.111029_bib90","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/S0028-3908(98)00141-5","article-title":"Transport of brain-derived neurotrophic factor across the blood-brain barrier","volume":"37","author":"Pan","year":"1998","journal-title":"Neuropharmacology"},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib91","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-71317-y","article-title":"Serum BDNF levels correlate with regional cortical thickness in minor depression: a pilot study","volume":"10","author":"Polyakova","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.abb.2026.111029_bib92","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jpsychires.2023.05.060","article-title":"BDNF and stress\/mood-related interactions on emotional disorder symptoms, executive functioning, and deliberate self-harm","volume":"163","author":"Guillot","year":"2023","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.abb.2026.111029_bib93","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.pnpbp.2018.07.010","article-title":"Serum level of brain-derived neurotrophic factor in Parkinson's disease: a meta-analysis","volume":"88","author":"Jiang","year":"2019","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib94","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s12017-025-08857-x","article-title":"Unlocking Alzheimer's disease: the role of BDNF signaling in neuropathology and treatment","volume":"27","author":"Alqahtani","year":"2025","journal-title":"Neuromolecular Med."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib95","article-title":"Brain-derived neurotrophic factor (BDNF) levels in panic disorder: a systematic review and meta-analysis","volume":"14","author":"Shafiee","year":"2024","journal-title":"Brain Behav."},{"issue":"15\u201316","key":"10.1016\/j.abb.2026.111029_bib96","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1177\/1535370218815612","article-title":"Brain-derived neurotrophic factor in peripheral blood mononuclear cells and stroke outcome","volume":"243","author":"Pedard","year":"2018","journal-title":"Exp. Biol. Med. (Maywood)"},{"issue":"2","key":"10.1016\/j.abb.2026.111029_bib97","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0306-4522(93)90196-M","article-title":"Systemic interleukin-1 beta decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formation","volume":"53","author":"Lapchak","year":"1993","journal-title":"Neuroscience"},{"key":"10.1016\/j.abb.2026.111029_bib98","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.3889\/oamjms.2021.6840","article-title":"Negative correlation between serum brain-derived neurotrophic factor levels and obesity predictor markers and inflammation levels in females with obesity","volume":"9","author":"Raharjo","year":"2021","journal-title":"Macedonian J. Med. Sci."},{"key":"10.1016\/j.abb.2026.111029_bib99","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.662407","article-title":"BDNF as a biomarker of cognition in schizophrenia\/psychosis: an updated review","volume":"12","author":"Nieto","year":"2021","journal-title":"Front. Psychiatr."},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib100","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1080\/02687038.2025.2461761","article-title":"Brain-derived neurotrophic factor (BDNF) as a biomarker in stroke-induced aphasia recovery: a scoping review","volume":"40","author":"Mayes","year":"2026","journal-title":"Aphasiology"},{"issue":"41","key":"10.1016\/j.abb.2026.111029_bib101","doi-asserted-by":"crossref","first-page":"15064","DOI":"10.1021\/acs.jafc.3c03183","article-title":"Red cabbage anthocyanins attenuate cognitive impairment by attenuating neuroinflammation and regulating gut microbiota in aging mice","volume":"71","author":"Zhang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.abb.2026.111029_bib102","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7340881","article-title":"Blueberry anthocyanins extract attenuates acrylamide-induced oxidative stress and neuroinflammation in rats","volume":"2022","author":"Fang","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.abb.2026.111029_bib103","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2019.103757","article-title":"Ameliorative effect of anthocyanin on depression mice by increasing monoamine neurotransmitter and up-regulating BDNF expression","volume":"66","author":"Fang","year":"2020","journal-title":"J. Funct.Foods"},{"issue":"11","key":"10.1016\/j.abb.2026.111029_bib104","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1080\/1028415X.2022.2126757","article-title":"Effect of consumption of blue maize tortilla on anxiety-like behaviour, learning, memory and hippocampal BDNF expression in a chronic stress model in rats","volume":"26","author":"Aguirre L\u00f3pez","year":"2023","journal-title":"Nutr. Neurosci."},{"issue":"5","key":"10.1016\/j.abb.2026.111029_bib105","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1007\/s00394-024-03381-3","article-title":"Short-term Aronia melanocarpa extract supplementation improves cognitive performance: a randomized, double-blind, placebo-controlled cross-over study in healthy young adults","volume":"63","author":"Ahles","year":"2024","journal-title":"Eur. J. Nutr."},{"issue":"16","key":"10.1016\/j.abb.2026.111029_bib106","doi-asserted-by":"crossref","DOI":"10.3390\/nu15163499","article-title":"A randomized, double-blind, placebo-controlled study of an anthocyanin-rich functional ingredient on cognitive function and eye dryness in late adulthood volunteers: roles of epigenetic and gut microbiome modulations","volume":"15","author":"Wattanathorn","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.abb.2026.111029_bib107","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3233\/NHA-180056","article-title":"Acute effects of flavonoid-rich blueberry on cognitive and vascular function in healthy older adults","volume":"5","author":"Dodd","year":"2019","journal-title":"Nutr. Healthy Aging"},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib108","doi-asserted-by":"crossref","DOI":"10.3390\/nu14010001","article-title":"Neurocognitive effects of cocoa and red-berries consumption in healthy adults","volume":"14","author":"Garc\u00eda-Cordero","year":"2021","journal-title":"Nutrients"},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib109","doi-asserted-by":"crossref","first-page":"3946","DOI":"10.1039\/D6FO00793G","article-title":"Consumption of an anthocyanin-rich extract increases circulating BDNF and BDNF gene expression in healthy subjects consuming a high-fat meal","volume":"17","author":"Zhu","year":"2026","journal-title":"Food Funct."},{"key":"10.1016\/j.abb.2026.111029_bib110","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.849902","article-title":"Chronic consumption of cranberries (Vaccinium macrocarpon) for 12 weeks improves episodic memory and regional brain perfusion in healthy older adults: a randomised, placebo-controlled, parallel-groups feasibility study","volume":"9","author":"Flanagan","year":"2022","journal-title":"Front. Nutr."},{"issue":"13","key":"10.1016\/j.abb.2026.111029_bib111","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202300502","article-title":"Effects of anthocyanins on cognition and vascular function: a systematic review","volume":"68","author":"Ellis","year":"2024","journal-title":"Mol. Nutr. Food Res."},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib112","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/j.2040-4603.2014.tb00576.x","article-title":"HPA axis-rhythms","volume":"4","author":"Spiga","year":"2014","journal-title":"Compr. Physiol."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib113","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.4103\/NRR.NRR-D-24-00355","article-title":"Glucocorticoid receptor signaling in the brain and its involvement in cognitive function","volume":"20","author":"Su","year":"2025","journal-title":"Neural Regen. Res."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib114","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1152\/physrev.00022.2020","article-title":"Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation","volume":"101","author":"Claassen","year":"2021","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.abb.2026.111029_bib115","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.neuroscience.2012.08.065","article-title":"Glucocorticoid regulation of brain-derived neurotrophic factor: relevance to hippocampal structural and functional plasticity","volume":"239","author":"Suri","year":"2013","journal-title":"Neuroscience"},{"issue":"19","key":"10.1016\/j.abb.2026.111029_bib116","doi-asserted-by":"crossref","first-page":"7705","DOI":"10.1039\/D5FO02698A","article-title":"Black mulberry anthocyanins induce antidepressant-like effects via the BDNF\/TrkB signaling pathway","volume":"16","author":"Wang","year":"2025","journal-title":"Food Funct."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib117","doi-asserted-by":"crossref","first-page":"6315","DOI":"10.1002\/fsn3.4280","article-title":"Identification, quantification, and antidepressant-like evaluation of anthocyanin-rich extracts from different dietary berries","volume":"12","author":"Wang","year":"2024","journal-title":"Food Sci. Nutr."},{"issue":"23","key":"10.1016\/j.abb.2026.111029_bib118","doi-asserted-by":"crossref","DOI":"10.3390\/ijms262311568","article-title":"Short-term New Zealand 'Blackadder' Blackcurrant juice supplementation improves learning and memory in young adult rats","volume":"26","author":"Lomiwes","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.abb.2026.111029_bib119","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/5520059","article-title":"The positive modulation effect of a 6-week consumption of an anthocyanin-rich mulberry milk on working memory, cholinergic, and monoaminergic functions in healthy working-age adults","volume":"2021","author":"Thukham-Mee","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"5","key":"10.1016\/j.abb.2026.111029_bib120","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1007\/s00394-017-1467-2","article-title":"Cranberry (Vaccinium macrocarpon) extract treatment improves triglyceridemia, liver cholesterol, liver steatosis, oxidative damage and corticosteronemia in rats rendered obese by high fat diet","volume":"57","author":"Peixoto","year":"2018","journal-title":"Eur. J. Nutr."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib121","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1039\/D4FO05065G","article-title":"Anthocyanin-rich black wheat as a functional food for managing type 2 diabetes mellitus: a study on high fat diet-streptozotocin-induced diabetic rats","volume":"16","author":"Tiwari","year":"2025","journal-title":"Food Funct."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib122","doi-asserted-by":"crossref","first-page":"110","DOI":"10.4162\/nrp.2024.18.1.110","article-title":"Positive effects of anthocyanin-rich mulberry milk on mental health problems in the working population: an open-label study","volume":"18","author":"Rangseekajee","year":"2024","journal-title":"Nutr. Res. Prac."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib123","article-title":"Monoamine oxidase A (MAO-A): a signature marker of alternatively activated monocytes\/macrophages","volume":"1","author":"Cathcart","year":"2014","journal-title":"Inflamm. Cell. Signal"},{"issue":"10","key":"10.1016\/j.abb.2026.111029_bib124","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1210\/js.2019-00158","article-title":"Glucocorticoid and mineralocorticoid receptors in the brain: a transcriptional perspective","volume":"3","author":"Koning","year":"2019","journal-title":"J. Endocr. Soc."},{"key":"10.1016\/j.abb.2026.111029_bib125","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2022.109158","article-title":"(-)-Epicatechin mitigates anxiety-related behavior in a mouse model of high fat diet-induced obesity","volume":"110","author":"Kang","year":"2022","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.abb.2026.111029_bib126","doi-asserted-by":"crossref","DOI":"10.1016\/j.metop.2025.100381","article-title":"High-fat diet may increase the risk of insulin resistance by inducing dysbiosis","volume":"27","author":"Abbasi","year":"2025","journal-title":"Metabol. Open"},{"key":"10.1016\/j.abb.2026.111029_bib127","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.3389\/fimmu.2018.02649","article-title":"Inflammatory links between high fat diets and diseases","volume":"9","author":"Duan","year":"2018","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib128","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1007\/s12035-021-02283-3","article-title":"Targeting insulin resistance to treat cognitive dysfunction","volume":"58","author":"Tyagi","year":"2021","journal-title":"Mol. Neurobiol."},{"issue":"3","key":"10.1016\/j.abb.2026.111029_bib129","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1177\/13872877251385255","article-title":"The longitudinal association between dyslipidemia and cognitive trajectory","volume":"108","author":"Pink","year":"2025","journal-title":"J. Alzheimers Dis."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib130","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.bbalip.2012.11.012","article-title":"Cyanidin is an agonistic ligand for peroxisome proliferator-activated receptor-alpha reducing hepatic lipid","volume":"1831","author":"Jia","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"issue":"7","key":"10.1016\/j.abb.2026.111029_bib131","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1002\/ptr.6379","article-title":"Anthocyanins ameliorate palmitate-induced inflammation and insulin resistance in 3T3-L1 adipocytes","volume":"33","author":"Muscar\u00e0","year":"2019","journal-title":"Phytother Res."},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib132","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1021\/jf1043508","article-title":"Mulberry water extracts possess an anti-obesity effect and ability to inhibit hepatic lipogenesis and promote lipolysis","volume":"59","author":"Peng","year":"2011","journal-title":"J. Agric. Food Chem."},{"issue":"8","key":"10.1016\/j.abb.2026.111029_bib133","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.1039\/D0FO03245J","article-title":"Purple grumixama anthocyanins (Eugenia brasiliensis Lam.) attenuate obesity and insulin resistance in high-fat diet mice","volume":"12","author":"Teixeira","year":"2021","journal-title":"Food Funct."},{"key":"10.1016\/j.abb.2026.111029_bib134","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.redox.2018.05.012","article-title":"Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice","volume":"18","author":"Daveri","year":"2018","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib135","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1093\/jn\/nxab029","article-title":"(-)-Epicatechin and anthocyanins modulate GLP-1 metabolism: evidence from C57BL\/6J mice and GLUTag cells","volume":"151","author":"Cremonini","year":"2021","journal-title":"J. Nutr."},{"issue":"2","key":"10.1016\/j.abb.2026.111029_bib136","doi-asserted-by":"crossref","first-page":"202","DOI":"10.3945\/jn.113.184358","article-title":"Intakes of anthocyanins and flavones are associated with biomarkers of insulin resistance and inflammation in women","volume":"144","author":"Jennings","year":"2014","journal-title":"J. Nutr."},{"issue":"10","key":"10.1016\/j.abb.2026.111029_bib137","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.3945\/jn.110.125336","article-title":"Bioactives in blueberries improve insulin sensitivity in obese, insulin-resistant men and women","volume":"140","author":"Stull","year":"2010","journal-title":"J. Nutr."},{"issue":"17","key":"10.1016\/j.abb.2026.111029_bib138","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21176241","article-title":"Induction of adipose tissue browning as a strategy to combat obesity","volume":"21","author":"Kury\u0142owicz","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"22","key":"10.1016\/j.abb.2026.111029_bib139","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242216480","article-title":"Glucose transport and utilization in the hippocampus: from neurophysiology to diabetes-related development of dementia","volume":"24","author":"Yonamine","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.abb.2026.111029_bib140","doi-asserted-by":"crossref","first-page":"536","DOI":"10.3389\/fgene.2019.00536","article-title":"Effects of anthocyanin supplementation on serum lipids, glucose, markers of inflammation and cognition in adults with increased risk of dementia - a pilot study","volume":"10","author":"Bergland","year":"2019","journal-title":"Front. Genet."},{"issue":"4","key":"10.1016\/j.abb.2026.111029_bib141","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/jnr.20752","article-title":"Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats","volume":"83","author":"Tanaka","year":"2006","journal-title":"J. Neurosci. Res."},{"issue":"7\u20139","key":"10.1016\/j.abb.2026.111029_bib142","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1177\/15230864251401591","article-title":"Cytokine-microglia interactions in neuroinflammation: mechanisms, disease dynamics, and therapeutic strategies","volume":"44","author":"Zhang","year":"2026","journal-title":"Antioxidants Redox Signal."},{"issue":"6","key":"10.1016\/j.abb.2026.111029_bib143","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1159\/000110455","article-title":"Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease","volume":"20","author":"Walter","year":"2007","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.abb.2026.111029_bib144","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.bbr.2016.03.010","article-title":"Anthocyanin effects on microglia M1\/M2 phenotype: consequence on neuronal fractalkine expression","volume":"305","author":"Meireles","year":"2016","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.abb.2026.111029_bib145","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/4051232","article-title":"Blackberry and blueberry anthocyanin supplementation counteract high-fat-diet-induced obesity by alleviating oxidative stress and inflammation and accelerating energy expenditure","volume":"2018","author":"Wu","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"9","key":"10.1016\/j.abb.2026.111029_bib146","doi-asserted-by":"crossref","DOI":"10.3390\/nu11091966","article-title":"Effect of anthocyanin-rich tart cherry extract on inflammatory mediators and adipokines involved in type 2 diabetes in a high fat diet induced obesity mouse model","volume":"11","author":"Nemes","year":"2019","journal-title":"Nutrients"},{"issue":"7","key":"10.1016\/j.abb.2026.111029_bib147","doi-asserted-by":"crossref","first-page":"3970","DOI":"10.1021\/jf902852d","article-title":"Purified blueberry anthocyanins and blueberry juice alter development of obesity in mice fed an obesogenic high-fat diet","volume":"58","author":"Prior","year":"2010","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib148","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.abb.2010.04.005","article-title":"Antioxidant actions of flavonoids: thermodynamic and kinetic analysis","volume":"501","author":"Galleano","year":"2010","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.abb.2026.111029_bib149","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102927","article-title":"(Poly)phenols and the regulation of NADPH oxidases","volume":"67","author":"Fraga","year":"2023","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.abb.2026.111029_bib150","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13065-020-00690-6","article-title":"Consumption of anthocyanin-rich beverages affects Nrf2 and Nrf2-dependent gene transcription in peripheral lymphocytes and DNA integrity of healthy volunteers","volume":"14","author":"Groh","year":"2020","journal-title":"BMC Chem."},{"issue":"11","key":"10.1016\/j.abb.2026.111029_bib151","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.2174\/1570159X20666220119140835","article-title":"Neuroinflammation: the role of anthocyanins as neuroprotectants","volume":"20","author":"Banji","year":"2022","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.abb.2026.111029_bib152","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.92941.3","article-title":"Reliance on self-reports and estimated food composition data in nutrition research introduces significant bias that can only be addressed with biomarkers","volume":"13","author":"Ottaviani","year":"2024","journal-title":"eLife"}],"container-title":["Archives of Biochemistry and Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986126003024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003986126003024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T14:52:55Z","timestamp":1793026375000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003986126003024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":154,"alternative-id":["S0003986126003024"],"URL":"https:\/\/doi.org\/10.1016\/j.abb.2026.111029","relation":{},"ISSN":["0003-9861"],"issn-type":[{"value":"0003-9861","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anthocyanins and brain health in the context of obesity and Western-style diets","name":"articletitle","label":"Article Title"},{"value":"Archives of Biochemistry and Biophysics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abb.2026.111029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111029"}}