{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T19:11:24Z","timestamp":1789067484864,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T00:00:00Z","timestamp":1595376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anais Brasileiros de Dermatologia"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.abd.2020.07.001","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T21:48:13Z","timestamp":1596577693000},"page":"702-707","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Blood microRNA expressions in patients with mild to moderate psoriasis and the relationship between microRNAs and psoriasis activity"],"prefix":"10.1016","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5727-9474","authenticated-orcid":false,"given":"Emine Tugba","family":"Alatas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0230-4214","authenticated-orcid":false,"given":"Murat","family":"Kara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-9417","authenticated-orcid":false,"given":"Gursoy","family":"Dogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4197-9716","authenticated-orcid":false,"given":"Asl\u0131","family":"Ak\u0131n Belli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.abd.2020.07.001_bib0185","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.clindermatol.2007.08.007","article-title":"Psoriasis: epidemiology","volume":"25","author":"Gudjonsson","year":"2007","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0190","series-title":"Clinical dermatology: a color guide to diagnosis and therapy","author":"Habif","year":"2016"},{"key":"10.1016\/j.abd.2020.07.001_bib0195","series-title":"Fitzpatrick's dermatology in general medicine","first-page":"213","article-title":"Psoriasis","author":"Gudjonsson","year":"2012"},{"key":"10.1016\/j.abd.2020.07.001_bib0200","series-title":"Dermatology","first-page":"138","article-title":"Psoriasis","author":"Van de Kerkhof","year":"2018"},{"key":"10.1016\/j.abd.2020.07.001_bib0205","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jaut.2015.07.008","article-title":"The immunogenetics of psoriasis: a comprehensive review","volume":"64","author":"Harden","year":"2015","journal-title":"J Autoimmun"},{"key":"10.1016\/j.abd.2020.07.001_bib0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2249.2004.02310.x","article-title":"Immunopathogenic mechanisms in psoriasis","volume":"135","author":"Gudjonsson","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.abd.2020.07.001_bib0215","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1097\/FJC.0b013e3181f581ba","article-title":"Role of microRNAs in cardiac preconditioning","volume":"56","author":"Salloum","year":"2010","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.abd.2020.07.001_bib0220","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/exd.13275","article-title":"The expanding microRNA world in psoriasis","volume":"26","author":"Sonkoly","year":"2017","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0225","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.clinbiochem.2011.04.021","article-title":"Association between SNPs in pre-miRNA and risk of chronic obstructive pulmonary disease","volume":"44","author":"Li","year":"2011","journal-title":"Clin Biochem"},{"key":"10.1016\/j.abd.2020.07.001_bib0230","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1111\/exd.12469","article-title":"Genetic polymorphisms altering microRNA activity in psoriasis \u2013 a key to solve the puzzle of missing heritability?","volume":"23","author":"Pivarcsi","year":"2014","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0235","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jdermsci.2014.05.005","article-title":"MicroRNA-223 and miR-143 are important systemic biomarkers for disease activity in psoriasis","volume":"75","author":"L\u00f8vendorf","year":"2014","journal-title":"J Dermatol Sci"},{"key":"10.1016\/j.abd.2020.07.001_bib0240","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.cyto.2012.07.031","article-title":"Regulation of pro-inflammatory cytokines TNF\u03b1 and IL24 by microRNA-203 in primary keratinocytes","volume":"60","author":"Primo","year":"2012","journal-title":"Cytokine"},{"key":"10.1016\/j.abd.2020.07.001_bib0245","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.clim.2013.10.009","article-title":"Up-regulation of microRNA-210 induces immune dysfunction via targeting FOXP3 in CD4(+) T cells of psoriasis vulgaris","volume":"150","author":"Zhao","year":"2014","journal-title":"Clin Immunol"},{"key":"10.1016\/j.abd.2020.07.001_bib0250","doi-asserted-by":"crossref","first-page":"e610","DOI":"10.1371\/journal.pone.0000610","article-title":"MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?","volume":"2","author":"Sonkoly","year":"2007","journal-title":"PLoS ONE"},{"key":"10.1016\/j.abd.2020.07.001_bib0255","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1111\/jcmm.12359","article-title":"A single-nucleotide polymorphism of miR-146a and psoriasis: an association and functional study","volume":"18","author":"Zhang","year":"2014","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.abd.2020.07.001_bib0260","doi-asserted-by":"crossref","first-page":"3702","DOI":"10.1172\/JCI94012","article-title":"MiR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity","volume":"127","author":"Li","year":"2017","journal-title":"J Clin Invest"},{"key":"10.1016\/j.abd.2020.07.001_bib0265","doi-asserted-by":"crossref","first-page":"392","DOI":"10.2340\/00015555-1086","article-title":"Effect of narrow-band ultraviolet B phototherapy on p63 and microRNA (miR-21 and miR-125b) expression in psoriatic epidermis","volume":"91","author":"Gu","year":"2011","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.abd.2020.07.001_bib0270","doi-asserted-by":"crossref","DOI":"10.4238\/gmr.15038631","article-title":"Increased miR-155-5p expression in dermal mesenchymal stem cells of psoriatic patients: comparing the microRNA expression profile by microarray","volume":"15","author":"Hou","year":"2016","journal-title":"Genet Mol Res"},{"key":"10.1016\/j.abd.2020.07.001_bib0275","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1684\/ejd.2013.2148","article-title":"Serum and skin levels of miR-369-3p in patients with psoriasis and their correlation with disease severity","volume":"23","author":"Guo","year":"2013","journal-title":"Eur J Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0280","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/1346-8138.12904","article-title":"Recent progress in studies of miRNA and skin diseases","volume":"42","author":"Jinnin","year":"2015","journal-title":"J Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0285","doi-asserted-by":"crossref","first-page":"e2030","DOI":"10.1097\/MD.0000000000002030","article-title":"An exploration of the role of microRNAs in psoriasis: a systematic review of the literature","volume":"94","author":"Huang","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.abd.2020.07.001_bib0290","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/bjd.13721","article-title":"Changes in mRNA expression precede changes in microRNA expression in lesional psoriatic skin during treatment with adalimumab","volume":"173","author":"Raaby","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0295","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/bjd.12381","article-title":"Changes in the level of serum microRNAs in patients with psoriasis after antitumour necrosis factor-\u03b1 therapy","volume":"169","author":"Pivarcsi","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0300","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1111\/j.1365-2133.2011.10497.x","article-title":"microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris","volume":"165","author":"Ichihara","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0305","first-page":"167","article-title":"Upregulation of miR-498 suppresses Th17 cell differentiation by targeting STAT3 in rheumatoid arthritis patients","volume":"70","author":"Xiang","year":"2018","journal-title":"Acta Physiol Sinica"},{"key":"10.1016\/j.abd.2020.07.001_bib0310","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s13059-016-0901-8","article-title":"Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease","volume":"17","author":"Wang","year":"2016","journal-title":"Genome Biol"},{"key":"10.1016\/j.abd.2020.07.001_bib0315","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.3389\/fimmu.2018.01323","article-title":"The interleukin-23\/interleukin-17 axis links adaptive and innate immunity in psoriasis","volume":"9","author":"Sch\u00f6n","year":"2018","journal-title":"Front Immunol"},{"key":"10.1016\/j.abd.2020.07.001_bib0320","first-page":"1198","article-title":"Anti-\u03b1 blockers. Overview of reports on the effectiveness of therapy with IL-12\/IL-23 and T and B lymphocyte inhibitors","volume":"70","author":"Wcis\u0142o-Dziadecka","year":"2016","journal-title":"Postepy Hig Med Dosw (Online)"},{"key":"10.1016\/j.abd.2020.07.001_bib0325","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1177\/1535370216669839","article-title":"Upregulation of microRNA-205 suppresses vascular endothelial growth factor expression-mediated PI3K\/Akt signaling transduction in human keloid fibroblasts","volume":"242","author":"An","year":"2017","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.abd.2020.07.001_bib0330","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1161\/CIRCRESAHA.115.307408","article-title":"VEGF-induced expression of miR-17-92 cluster in endothelial cells is mediated by ERK\/ELK1 activation and regulates angiogenesis","volume":"118","author":"Chamorro-Jorganes","year":"2016","journal-title":"Circ Res"},{"key":"10.1016\/j.abd.2020.07.001_bib0335","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1111\/exd.13727","article-title":"Serum vascular endothelial growth factor receptor 3 as a potential biomarker in psoriasis","volume":"27","author":"Hong","year":"2018","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.abd.2020.07.001_bib0340","doi-asserted-by":"crossref","first-page":"964069","DOI":"10.1155\/2014\/964069","article-title":"IL-6 as a druggable target in psoriasis: focus on pustular variants","volume":"2014","author":"Saggini","year":"2014","journal-title":"J Immunol Res"},{"key":"10.1016\/j.abd.2020.07.001_bib0345","doi-asserted-by":"crossref","first-page":"3772","DOI":"10.1093\/nar\/gkw205","article-title":"MiR-26 down-regulates TNF-\u03b1\/NF-\u03baB signalling and IL-6 expression by silencing HMGA1 and MALT1","volume":"44","author":"Chyi-Ying","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.abd.2020.07.001_bib0350","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3390\/ijms19010171","article-title":"A STAT3-centric view","volume":"19","author":"Calautti","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.abd.2020.07.001_bib0355","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12944-016-0216-5","article-title":"MiR-106b exhibits an anti-angiogenic function by inhibiting STAT3 expression in endothelial cells","volume":"15","author":"Maimaiti","year":"2016","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.abd.2020.07.001_bib0360","doi-asserted-by":"crossref","first-page":"20555","DOI":"10.18632\/oncotarget.4111","article-title":"Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-cell lymphoma","volume":"6","author":"Sibbesen","year":"2015","journal-title":"Oncotarget"}],"container-title":["Anais Brasileiros de Dermatologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0365059620302087?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0365059620302087?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T23:38:44Z","timestamp":1759793924000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0365059620302087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S0365059620302087"],"URL":"https:\/\/doi.org\/10.1016\/j.abd.2020.07.001","relation":{},"ISSN":["0365-0596"],"issn-type":[{"value":"0365-0596","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Blood microRNA expressions in patients with mild to moderate psoriasis and the relationship between microRNAs and psoriasis activity","name":"articletitle","label":"Article Title"},{"value":"Anais Brasileiros de Dermatologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abd.2020.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Sociedade Brasileira de Dermatologia. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}