{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T07:40:37Z","timestamp":1792050037111,"version":"4.4.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anais Brasileiros de Dermatologia"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.abd.2025.501127","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T07:19:36Z","timestamp":1750231176000},"page":"501127","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Analysis of the clinical and epidemiological profile of leprosy in Brazil and major regions"],"prefix":"10.1016","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9469-7042","authenticated-orcid":false,"given":"Al\u00edcia de Siqueira","family":"Sczmanski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5869-8453","authenticated-orcid":false,"given":"Lucas","family":"Pazin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0603-3685","authenticated-orcid":false,"given":"Thiago Mamoru","family":"Sakae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5800-1351","authenticated-orcid":false,"given":"Josete","family":"Mazon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.abd.2025.501127_bib0005","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1590\/S0037-86822003000300010","article-title":"[Leprosy in Brazil]","volume":"36","author":"Ara\u00fajo","year":"2003","journal-title":"Rev Soc Bras Med Trop."},{"key":"10.1016\/j.abd.2025.501127_bib0010","unstructured":"Minist\u00e9rio da Sa\u00fade. [Internet]. Secretariat of Science, Technology, Innovation and Strategic Health Supplies. Clinical Protocols and Therapeutic Guidelines. Leprosy Recommendation Report. 2022; N\u00ba 749. [cited 2022 Nov 20]. Available from: https:\/\/bvsms.saude.gov.br\/bvs\/publicacoes\/protocolo_clinico_diretrizes_terapeuticas_hanseniase.pdf."},{"key":"10.1016\/j.abd.2025.501127_bib0015","unstructured":"Minist\u00e9rio da Sa\u00fade. [Internet]. Practical guide on leprosy. Bras\u00edlia (DF): Ministry of Health; 2017. [cited 2022 Nov 20]. Avaiable from: https:\/\/www.gov.br\/saude\/pt-br\/centrais-de-conteudo\/publicacoes\/svsa\/hanseniase\/guia-pratico-de-hanseniase.pdf\/view."},{"key":"10.1016\/j.abd.2025.501127_bib0020","article-title":"Analysis of the clinical and epidemiological profile of hanseniasis in under 15-years in the past 10-years in a municipality located in the southwest of Maranh\u00e3o","volume":"15","author":"Carvalho","year":"2022","journal-title":"Acervo Sa\u00fade."},{"key":"10.1016\/j.abd.2025.501127_bib0025","unstructured":"SINAN [home page]. Basic Leprosy Indicators and Data in Brazilian Municipalities [cited 2022 Nov 20]. Available from: http:\/\/indicadoreshanseniase.aids.gov.br."},{"key":"10.1016\/j.abd.2025.501127_bib0030","unstructured":"TABNET [Datasus: Information Technology at the Service of SUS]. Leprosy Cases - Since 2001 (SINAN) [cited 2022 Nov 20]. Available from: http:\/\/tabnet.datasus.gov.br\/cgi\/tabcgi.exe?sinannet\/cnv\/hanswbr.def."},{"key":"10.1016\/j.abd.2025.501127_bib0035","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1590\/0034-7167-2017-0651","article-title":"Socioeconomic factors related to leprosy: an integrative literature review","volume":"72","author":"Leano","year":"2019","journal-title":"Rev Bras Enferm."},{"key":"10.1016\/j.abd.2025.501127_bib0040","series-title":"Spatial distribution of leprosy: a socio-political issue [thesis]","first-page":"199","author":"Pereira","year":"2018"},{"key":"10.1016\/j.abd.2025.501127_bib0045","unstructured":"Organiza\u00e7\u00e3o Mundial da Sa\u00fade. Leprosy (Resolution). Geneva; 1991 (World Health Assembly; Forty-fourth World Health Assembly). [cited 2023 Feb 10]. Avaiable from: https:\/\/www.leprosy-information.org\/resource\/leprosy-resolution-wha-449-forty-fourth-world-health-assembly-13-may-1991."},{"key":"10.1016\/j.abd.2025.501127_bib0050","series-title":"Guidelines for the surveillance, care and elimination of leprosy as a public health problem: technical-operational manual","year":"2016"},{"key":"10.1016\/j.abd.2025.501127_bib0055","doi-asserted-by":"crossref","DOI":"10.1590\/0034-7167-2018-0583","article-title":"High-risk areas of leprosy in Brazil between 2001-2015","volume":"73","author":"Rodrigues","year":"2020","journal-title":"Rev Bras Enferm."},{"key":"10.1016\/j.abd.2025.501127_bib0060","first-page":"75","article-title":"Diferencia\u00e7\u00e3o territorial da hansen\u00edase no Brasil","volume":"16","author":"Magalh\u00e3es","year":"2007","journal-title":"Epidemiol Serv Sa\u00fade."},{"key":"10.1016\/j.abd.2025.501127_bib0065","first-page":"268","article-title":"[Hansen\u2019s disease, social conditions, and deforestation in the Brazilian Amazon]","volume":"27","author":"Silva","year":"2010","journal-title":"Rev Panam Salud Publica."},{"key":"10.1016\/j.abd.2025.501127_bib0070","series-title":"Brazil: territory and society at the beginning of the 21st century","author":"Santos","year":"2021"},{"key":"10.1016\/j.abd.2025.501127_bib0075","article-title":"Leprosy detection and the Human Development Index of municipalities in Minas Gerais, Brazil","volume":"11","author":"Lana","year":"2009","journal-title":"Rev Eletr Enferm."},{"key":"10.1016\/j.abd.2025.501127_bib0080","doi-asserted-by":"crossref","DOI":"10.36295\/ASRO.2021.24182","article-title":"The Risk of Physical Environment on Leprosy Incidence in Subang District in 2019","volume":"24","author":"Komalaningsih","year":"2021","journal-title":"ASRO."},{"key":"10.1016\/j.abd.2025.501127_bib0085","doi-asserted-by":"crossref","first-page":"e415","DOI":"10.1002\/mco2.415","article-title":"Genome\u2010wide meta\u2010analysis and fine\u2010mapping prioritize potential causal variants and genes related to leprosy","volume":"4","author":"Wang","year":"2023","journal-title":"MedComm (2020)."},{"key":"10.1016\/j.abd.2025.501127_bib0090","doi-asserted-by":"crossref","first-page":"e269","DOI":"10.25248\/reas.e269.2019","article-title":"Clinical and epidemiological profile of patients with hanseniasis in a reference unit in the state of Par\u00e1","author":"Quaresma","year":"2019","journal-title":"Acervo Sa\u00fade."},{"key":"10.1016\/j.abd.2025.501127_bib0095","doi-asserted-by":"crossref","first-page":"141","DOI":"10.63845\/0fc7yt70","article-title":"Analysis of the hist\u00f3rical trend of leprosy evolution in a state in southern Brazil in the period 2001-2015","volume":"47","author":"Sakae","year":"2018","journal-title":"Arq Catarin Med."},{"key":"10.1016\/j.abd.2025.501127_bib0100","doi-asserted-by":"crossref","first-page":"90","DOI":"10.63845\/9gcgq271","article-title":"Clinical-epidemiological profile of leprosy patients in the far west of the state of Santa Catarina, 2004 to 2014","volume":"44","author":"Pal\u00fa","year":"2015","journal-title":"Arq Catarin Med."},{"key":"10.1016\/j.abd.2025.501127_bib0105","article-title":"Epidemiological characteristics of leprosy in elderly Brazilians and comparison with other age groups (2016-2018)","volume":"36","author":"Rocha","year":"2020","journal-title":"Cad Sa\u00fade P\u00fablica."},{"key":"10.1016\/j.abd.2025.501127_bib0110","doi-asserted-by":"crossref","first-page":"20","DOI":"10.11606\/S1518-8787.2018052000335","article-title":"Leprosy and gender in Brazil: trends in an endemic area of the Northeast region, 2001\u20132014","volume":"52","author":"Souza","year":"2018","journal-title":"Rev Sa\u00fade P\u00fablica."},{"key":"10.1016\/j.abd.2025.501127_bib0115","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1590\/S0102-311X2009000500004","article-title":"Leprosy in indigenous populations of Amazonas State, Brazil: an epidemiological study in the counties of Autazes, Eirunep\u00e9 and S\u00e3o Gabriel da Cachoeira (2000 to 2005)","volume":"25","author":"Imbiriba","year":"2009","journal-title":"Cad Sa\u00fade P\u00fablica."},{"key":"10.1016\/j.abd.2025.501127_bib0120","first-page":"27","article-title":"Perfil cl\u00ednico-epidemiol\u00f3gico de pacientes acometidos pela hansen\u00edase atendidos em uma unidade de refer\u00eancia","author":"Basso","year":"2017","journal-title":"Rev Soc Bras Cl\u00edn Med."},{"key":"10.1016\/j.abd.2025.501127_bib0125","doi-asserted-by":"crossref","first-page":"259","DOI":"10.14393\/Hygeia1862444","article-title":"Leprosy in a hyperendemic state: segmental trend and identification of spatial clusters with a high risk of transmission","volume":"18","author":"Silva","year":"2022","journal-title":"Hygeia."},{"key":"10.1016\/j.abd.2025.501127_bib0130","unstructured":"Instituto Brasileiro de Geografia e Estat\u00edstica [Cities and States page]. Brasil [cited 2022 Dec 03]. Available from: https:\/\/www.ibge.gov.br\/cidades-e-estados.html."},{"key":"10.1016\/j.abd.2025.501127_bib0135","doi-asserted-by":"crossref","first-page":"e1226","DOI":"10.1016\/S2214-109X(19)30260-8","article-title":"Socioeconomic determinants of leprosy new case detection in the 100 million brazilian cohort: a population-based linkage study","volume":"7","author":"Nery","year":"2019","journal-title":"Lancet Glob Health."},{"key":"10.1016\/j.abd.2025.501127_bib0140","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1590\/S0037-86822008000600006","article-title":"Clinical and epidemiological study of leprosy cases in the University Hospital of Bras\u00edlia: 20 years - 1985 to 2005","volume":"41","author":"Penna","year":"2008","journal-title":"Rev Soc Bras Med Trop."},{"key":"10.1016\/j.abd.2025.501127_bib0145","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1590\/abd1806-4841.201533963","article-title":"Epidemiological aspects of leprosy in Juazeiro-BA, from 2002 to 2012","volume":"90","author":"Silva","year":"2015","journal-title":"An Bras Dermatol."},{"key":"10.1016\/j.abd.2025.501127_bib0150","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1590\/abd1806-4841.20153385","article-title":"Evaluation of the social, clinical and laboratorial profile of patients diagnosed with leprosy in a reference center in S\u00e3o Paulo","volume":"90","author":"Porto","year":"2015","journal-title":"An Bras Dermatol."},{"key":"10.1016\/j.abd.2025.501127_bib0155","doi-asserted-by":"crossref","first-page":"353","DOI":"10.5205\/1981-8963-v13i2a236224p353-362-2019","article-title":"Clinical and epidemiological aspects of leprosy","volume":"13","author":"Nascimento Costa","year":"2019","journal-title":"Rev Enferm UFPE Line."},{"key":"10.1016\/j.abd.2025.501127_bib0160","article-title":"[Adherence to leprosy treatment by patients followed up in basic health units in Imperatriz-MA]","volume":"12","author":"Sousa","year":"2013","journal-title":"SANARE."},{"key":"10.1016\/j.abd.2025.501127_bib0165","first-page":"486","article-title":"Clinical-epidemiological character and degree of disability in patients with Hansen\u2019s disease in the municipality of Barbacena - MG and macro-region in the period from 2001 to 2010","volume":"24","author":"Mendes","year":"2014","journal-title":"Rev Med Minas Gerais."}],"container-title":["Anais Brasileiros de Dermatologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0365059625000698?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0365059625000698?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:20:54Z","timestamp":1753888854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0365059625000698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S0365059625000698"],"URL":"https:\/\/doi.org\/10.1016\/j.abd.2025.501127","relation":{},"ISSN":["0365-0596"],"issn-type":[{"value":"0365-0596","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of the clinical and epidemiological profile of leprosy in Brazil and major regions","name":"articletitle","label":"Article Title"},{"value":"Anais Brasileiros de Dermatologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.abd.2025.501127","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Sociedade Brasileira de Dermatologia. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"501127"}}