{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T02:44:08Z","timestamp":1792464248767,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.aca.2010.09.018","type":"journal-article","created":{"date-parts":[[2010,9,22]],"date-time":"2010-09-22T04:33:03Z","timestamp":1285129983000},"page":"32-40","source":"Crossref","is-referenced-by-count":31,"title":["High-performance liquid-chromatographic tandem-mass spectrometric methods for atropinesterase-mediated enantioselective and chiral determination of R- and S-hyoscyamine in plasma"],"prefix":"10.1016","volume":"680","author":[{"given":"Harald","family":"John","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Eyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Zilker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horst","family":"Thiermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2010.09.018_bib0005","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s002990050565","volume":"18","author":"Nakanishi","year":"1998","journal-title":"Plant Cell Rep."},{"key":"10.1016\/j.aca.2010.09.018_bib0010","series-title":"The Pharmacological Basis of Therapeutics","first-page":"141","author":"Brown","year":"1996"},{"key":"10.1016\/j.aca.2010.09.018_bib0015","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1046\/j.1460-9592.1997.d01-40.x","volume":"7","author":"Gervais","year":"1997","journal-title":"Paed. Anaesth."},{"key":"10.1016\/j.aca.2010.09.018_bib0020","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1034\/j.1600-0420.1999.770215.x","volume":"77","author":"Kaila","year":"1999","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.aca.2010.09.018_bib0025","series-title":"Clinical and Experimental Toxicology of Organophosphates and Carbamates","first-page":"543","author":"Heath","year":"1992"},{"key":"10.1016\/j.aca.2010.09.018_bib0030","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/bdd.2510160804","volume":"16","author":"Nyberg","year":"1995","journal-title":"Biopharm. Drug Dispos."},{"key":"10.1016\/j.aca.2010.09.018_bib0035","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0731-7085(95)01630-9","volume":"14","author":"Xu","year":"1995","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.aca.2010.09.018_bib0040","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jchromb.2007.09.035","volume":"859","author":"Siluk","year":"2007","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.aca.2010.09.018_bib0045","first-page":"439","volume":"60","author":"Grynkiewicz","year":"2008","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.aca.2010.09.018_bib0050","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1007\/s00216-009-3209-7","volume":"396","author":"John","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.aca.2010.09.018_bib0055","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/j.jchromb.2010.03.007","volume":"878","author":"Aehle","year":"2010","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.aca.2010.09.018_bib0060","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/BF02267937","volume":"35","author":"Bhushan","year":"1993","journal-title":"Chromatographia"},{"key":"10.1016\/j.aca.2010.09.018_bib0065","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0021-9673(99)00447-1","volume":"848","author":"Tahara","year":"1999","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2010.09.018_bib0070","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0021-9673(99)01230-3","volume":"868","author":"Mateus","year":"2000","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2010.09.018_bib0075","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1002\/1522-2683(200109)22:15<3308::AID-ELPS3308>3.0.CO;2-H","volume":"22","author":"Cherkaoui","year":"2001","journal-title":"Electrophoresis"},{"key":"10.1016\/j.aca.2010.09.018_bib0080","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1002\/1520-636X(2000)12:10<714::AID-CHIR3>3.0.CO;2-4","volume":"12","author":"Zhang","year":"2000","journal-title":"Chirality"},{"key":"10.1016\/j.aca.2010.09.018_bib0085","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0021-9673(02)00043-2","volume":"950","author":"Chen","year":"2002","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2010.09.018_bib0090","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.chroma.2005.02.073","volume":"1088","author":"Breton","year":"2005","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2010.09.018_bib0095","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0003-2697(87)90161-8","volume":"167","author":"Armstrong","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.aca.2010.09.018_bib0100","first-page":"369","volume":"5","author":"Kudo","year":"2000","journal-title":"Enantiomer"},{"key":"10.1016\/j.aca.2010.09.018_bib0105","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/BF00485951","volume":"12","author":"van Zutphen","year":"1974","journal-title":"Biochem. Genet."},{"key":"10.1016\/j.aca.2010.09.018_bib0110","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/BF00485952","volume":"12","author":"van Zutphen","year":"1974","journal-title":"Biochem. Genet."},{"key":"10.1016\/j.aca.2010.09.018_bib0115","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/j.1552-4604.1982.tb02638.x","volume":"22","author":"Adams","year":"1982","journal-title":"J. Clin. Pharmacol."},{"key":"10.1016\/j.aca.2010.09.018_bib0120","first-page":"211","article-title":"Zeitschrift der F K.K","volume":"3","author":"Schroff","year":"1852","journal-title":"Gesellschaft der \u00c4rzte Wien"},{"key":"10.1016\/j.aca.2010.09.018_bib0125","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1515\/bchm2.1974.355.1.529","volume":"355","author":"Moog","year":"1974","journal-title":"Hoppe-Seyle\u0155s Z. Physiol. Chem."},{"key":"10.1016\/j.aca.2010.09.018_bib0130","doi-asserted-by":"crossref","first-page":"165","DOI":"10.2165\/00139709-200322030-00004","volume":"22","author":"Eyer","year":"2003","journal-title":"Toxicol. Rev."},{"key":"10.1016\/j.aca.2010.09.018_bib0135","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/jat\/26.5.308","volume":"26","author":"Beike","year":"2002","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.aca.2010.09.018_bib0140","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jpba.2007.01.036","volume":"44","author":"Inoue","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.aca.2010.09.018_bib0145","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jchromb.2005.06.003","volume":"822","author":"Bicker","year":"2005","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.aca.2010.09.018_bib0150","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.jchromb.2010.01.003","volume":"878","author":"John","year":"2010","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.aca.2010.09.018_bib0155","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S1570-0232(02)00128-9","volume":"776","author":"Tsuge","year":"2002","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.aca.2010.09.018_bib0160","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.cbi.2005.10.036","volume":"157\u2013158","author":"Casida","year":"2005","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.aca.2010.09.018_bib0165","series-title":"Decontamination of Warfare Agents","first-page":"135","author":"Blum","year":"2008"},{"key":"10.1016\/j.aca.2010.09.018_bib0170","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1016\/0006-2952(93)90228-O","volume":"45","author":"Raveh","year":"1993","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.aca.2010.09.018_bib0175","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.tox.2006.11.066","volume":"233","author":"Lenz","year":"2007","journal-title":"Toxicology"}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267010011712?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267010011712?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,7]],"date-time":"2018-12-07T18:50:44Z","timestamp":1544208644000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267010011712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":35,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0003267010011712"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2010.09.018","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}