{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:48:37Z","timestamp":1790272117498,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003151","name":"Fonds de recherche du Qu\u00e9bec \u2013 Nature et technologies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003151","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.aca.2014.10.037","type":"journal-article","created":{"date-parts":[[2014,10,29]],"date-time":"2014-10-29T18:45:07Z","timestamp":1414608307000},"page":"415-424","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"special_numbering":"C","title":["Quantitative performance of liquid chromatography coupled to Q-Exactive high resolution mass spectrometry (HRMS) for the analysis of tetracyclines in a complex matrix"],"prefix":"10.1016","volume":"853","author":[{"given":"Morgan","family":"Solliec","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Roy-Lachapelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8584-1690","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Sauv\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3\u20134","key":"10.1016\/j.aca.2014.10.037_bib0005","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1051\/vetres:2001120","article-title":"Use of antimicrobials in veterinary medicine and mechanisms of resistance","volume":"32","author":"Schwarz","year":"2001","journal-title":"Vet. Res."},{"issue":"1","key":"10.1016\/j.aca.2014.10.037_bib0010","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/jac\/dkg293","article-title":"Significance of antibiotics in the environment","volume":"52","author":"Kummerer","year":"2003","journal-title":"J. Antimicrob. Chemother."},{"issue":"11","key":"10.1016\/j.aca.2014.10.037_bib0015","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1016\/j.jasms.2010.06.006","article-title":"Accurate mass measurement: terminology and treatment of data","volume":"21","author":"Brenton","year":"2010","journal-title":"J. Am. Soc. Mass Spectrom."},{"issue":"9","key":"10.1016\/j.aca.2014.10.037_bib0020","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M111.011015","article-title":"Mass spectrometry-based proteomics using Q Exactive, a high-performance benchtop quadrupole orbitrap mass spectrometer","volume":"10","author":"Michalski","year":"2011","journal-title":"Mol. Cell. Proteomics"},{"issue":"8","key":"10.1016\/j.aca.2014.10.037_bib0025","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/j.jasms.2009.03.002","article-title":"Quantitative-qualitative data acquisition using a benchtop orbitrap mass spectrometer","volume":"20","author":"Bateman","year":"2009","journal-title":"J. Am. Soc. Mass Spectrom."},{"issue":"15","key":"10.1016\/j.aca.2014.10.037_bib0030","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1002\/rcm.6628","article-title":"Comparison of the quantitative performance of a Q-Exactive high-resolution mass spectrometer with that of a triple quadrupole tandem mass spectrometer for the analysis of illicit drugs in wastewater","volume":"27","author":"Fedorova","year":"2013","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"49","key":"10.1016\/j.aca.2014.10.037_bib0035","doi-asserted-by":"crossref","first-page":"12088","DOI":"10.1021\/jf303939s","article-title":"Application of ultrahigh-performance liquid chromatography and electrospray ionization quadrupole orbitrap high-resolution mass spectrometry for determination of 166 pesticides in fruits and vegetables","volume":"60","author":"Wang","year":"2012","journal-title":"J. Agric. Food Chem."},{"issue":"4","key":"10.1016\/j.aca.2014.10.037_bib0040","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/jms.856","article-title":"The Orbitrap: a new mass spectrometer","volume":"40","author":"Hu","year":"2005","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.aca.2014.10.037_bib0045","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.aca.2013.04.017","article-title":"Targeted analysis with benchtop quadrupole\u2013orbitrap hybrid mass spectrometer: application to determination of synthetic hormones in animal urine","volume":"780","author":"Kumar","year":"2013","journal-title":"Anal. Chim. Acta"},{"issue":"22","key":"10.1016\/j.aca.2014.10.037_bib0050","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1016\/j.chroma.2009.03.073","article-title":"Simultaneous determination of tetracyclines and their degradation products in environmental waters by liquid chromatography\u2013electrospray tandem mass spectrometry","volume":"1216","author":"Jia","year":"2009","journal-title":"J. Chromatogr. A"},{"issue":"1-2","key":"10.1016\/j.aca.2014.10.037_bib0055","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.chroma.2005.08.027","article-title":"Simultaneous extraction and analysis of 11 tetracycline and sulfonamide antibiotics in influent and effluent domestic wastewater by solid-phase extraction and liquid chromatography\u2013electro spray ionization tandem mass spectrometry","volume":"1097","author":"Yang","year":"2005","journal-title":"J. Chromatogr. A"},{"issue":"18","key":"10.1016\/j.aca.2014.10.037_bib0060","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1002\/rcm.1598","article-title":"Quantitative determination of trace concentrations of tetracycline and sulfonamide antibiotics in surface water using solid-phase extraction and liquid chromatography\/ion trap tandem mass spectrometry","volume":"18","author":"Yang","year":"2004","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"6","key":"10.1016\/j.aca.2014.10.037_bib0065","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/jms.1921","article-title":"It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS","volume":"46","author":"Ramanathan","year":"2011","journal-title":"J. Mass Spectrom."},{"issue":"1","key":"10.1016\/j.aca.2014.10.037_bib0070","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.aca.2010.05.020","article-title":"Comprehensive comparison of liquid chromatography selectivity as provided by two types of liquid chromatography detectors (high resolution mass spectrometry and tandem mass spectrometry): Where is the crossover point?","volume":"673","author":"Kaufmann","year":"2010","journal-title":"Anal. Chimica Acta"},{"issue":"3","key":"10.1016\/j.aca.2014.10.037_bib0075","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jasms.2008.11.002","article-title":"Full-scan accurate mass selectivity of ultra-performance liquid chromatography combined with time-of-flight and orbitrap mass spectrometry in hormone and veterinary drug residue analysis","volume":"20","author":"van der Heeft","year":"2009","journal-title":"J. Am. Soc. Mass Spectrom."},{"issue":"8","key":"10.1016\/j.aca.2014.10.037_bib0080","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1021\/pr800264t","article-title":"A proteomics grade electron transfer dissociation-enabled hybrid linear ion trap\u2013orbitrap mass spectrometer","volume":"7","author":"McAlister","year":"2008","journal-title":"J. Proteome Res."},{"issue":"1","key":"10.1016\/j.aca.2014.10.037_bib0085","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.clinbiochem.2010.08.018","article-title":"HPLC\u2014high resolution mass spectrometry in clinical laboratory?","volume":"44","author":"Jiwan","year":"2011","journal-title":"Clin. Biochem."},{"issue":"4","key":"10.1016\/j.aca.2014.10.037_bib0090","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/j.talanta.2004.05.006","article-title":"Ultrasonic extraction of veterinary antibiotics from soils and pig slurry with SPE clean-up and LC\u2013UV and fluorescence detection","volume":"64","author":"Blackwell","year":"2004","journal-title":"Talanta"},{"issue":"1\u20132","key":"10.1016\/j.aca.2014.10.037_bib0095","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.chroma.2004.05.063","article-title":"Fast and robust simultaneous determination of three veterinary antibiotics in groundwater and surface water using a tandem solid-phase extraction with high-performance liquid chromatography-UV detection","volume":"1045","author":"Blackwell","year":"2004","journal-title":"J. Chromatogr. A"},{"issue":"1","key":"10.1016\/j.aca.2014.10.037_bib0100","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0021-9673(98)00755-9","article-title":"Stability studies of tetracycline in methanol solution","volume":"827","author":"Liang","year":"1998","journal-title":"J. Chromatogr. A"},{"issue":"2","key":"10.1016\/j.aca.2014.10.037_bib0105","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1021\/pr100780b","article-title":"24-hour lock mass protection","volume":"10","author":"Lee","year":"2011","journal-title":"J. Proteome Res."},{"issue":"12","key":"10.1016\/j.aca.2014.10.037_bib0110","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1074\/mcp.T500030-MCP200","article-title":"Parts per million mass accuracy on an orbitrap mass spectrometer via lock mass injection into a C-trap","volume":"4","author":"Olsen","year":"2005","journal-title":"Mol. Cell. Proteomics"},{"issue":"19","key":"10.1016\/j.aca.2014.10.037_bib0115","doi-asserted-by":"crossref","first-page":"4640","DOI":"10.1021\/ac010514w","article-title":"Analysis of trace levels of sulfonamide and tetracycline antimicrobials, in groundwater and surface water using solid-phase extraction and liquid chromatography\/mass spectrometry","volume":"73","author":"Lindsey","year":"2001","journal-title":"Anal. Chem."},{"issue":"10","key":"10.1016\/j.aca.2014.10.037_bib0120","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1021\/jf050065r","article-title":"Validation of an analytical methodology for determination of oxytetracycline and tetracycline residues in honey by HPLC with fluorescence detection","volume":"53","author":"Pena","year":"2005","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2014.10.037_bib0125","first-page":"162","article-title":"Validation of an analytical methodology for determination of oxytetracycline residue in milk by HPLC with UV detection","volume":"55","author":"Bakhtiarian","year":"2009","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.aca.2014.10.037_bib0130","first-page":"U629","article-title":"Investigating the molecular interactions of oxytetracycline in clay and organic matter: insights on factors affecting its mobility in soil","volume":"228","author":"Kulshrestha","year":"2004","journal-title":"Abstr. Pap. Am. Chem. Soc."},{"issue":"12","key":"10.1016\/j.aca.2014.10.037_bib0135","doi-asserted-by":"crossref","first-page":"2874","DOI":"10.1016\/j.watres.2004.03.017","article-title":"Potentiometric determination of acid dissociation constants (pK(a)) for human and veterinary antibiotics","volume":"38","author":"Qiang","year":"2004","journal-title":"Water Res."},{"issue":"4","key":"10.1016\/j.aca.2014.10.037_bib0140","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1021\/ic00056a015","volume":"32","author":"Jezowskabojczuk","year":"1993","journal-title":"Inorgan. Chem."},{"issue":"1-2","key":"10.1016\/j.aca.2014.10.037_bib0145","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.chroma.2004.03.034","article-title":"Simultaneous extraction of tetracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase extraction and liquid chromatography\u2013tandem mass spectrometry","volume":"1038","author":"Jacobsen","year":"2004","journal-title":"J. Chromatogr. A"},{"issue":"7","key":"10.1016\/j.aca.2014.10.037_bib0150","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1021\/ac015588m","article-title":"Determination of persistent tetracycline residues in soil fertilized with liquid manure by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry","volume":"74","author":"Hamscher","year":"2002","journal-title":"Anal. Chem."},{"issue":"5","key":"10.1016\/j.aca.2014.10.037_bib0155","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1007\/s00216-005-0261-9","article-title":"Multi-component analysis of tetracyclines: sulfonamides and tylosin in swine manure by liquid chromatography\u2013tandem mass spectrometry","volume":"384","author":"Jacobsen","year":"2006","journal-title":"Anal. Bioanal. Chem."},{"issue":"18","key":"10.1016\/j.aca.2014.10.037_bib0160","doi-asserted-by":"crossref","first-page":"7165","DOI":"10.1021\/jf050415+","article-title":"Determination of the persistence of tetracycline antibiotics and their degradates in manure-amended soil using enzyme-linked immunosorbent assay and liquid chromatography\u2013mass spectrometry","volume":"53","author":"Aga","year":"2005","journal-title":"J. Agric. Food Chem."},{"issue":"6","key":"10.1016\/j.aca.2014.10.037_bib0165","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1046\/j.1439-0442.2000.00300.x","article-title":"Stability of tetracycline in water and liquid manure","volume":"47","author":"Kuhne","year":"2000","journal-title":"J. Vet. Med. Ser. A-Physiol. Pathol. Clin. Med."},{"issue":"1\u20132","key":"10.1016\/j.aca.2014.10.037_bib0170","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0021-9673(97)01278-8","article-title":"Mass spectrometric analysis of tetracycline antibiotics in foods","volume":"812","author":"Oka","year":"1998","journal-title":"J. Chromatogr. A"},{"issue":"8","key":"10.1016\/j.aca.2014.10.037_bib0175","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.jasms.2009.05.010","article-title":"Full scan ms in comprehensive qualitative and quantitative residue analysis in food and feed matrices: How much resolving power is required?","volume":"20","author":"Kellmann","year":"2009","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"10.1016\/j.aca.2014.10.037_bib0180","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.chroma.2012.08.029","article-title":"Matrix effects and recovery calculations in analyses of pharmaceuticals based on the determination of beta-blockers and beta-agonists in environmental samples","volume":"1258","author":"Caban","year":"2012","journal-title":"J. Chromatogr. A"},{"issue":"1\u20132","key":"10.1016\/j.aca.2014.10.037_bib0185","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.aca.2004.08.055","article-title":"The ion suppression phenomenon in liquid chromatography\u2013mass spectrometry and its consequences in the field of residue","volume":"529","author":"Antignac","year":"2005","journal-title":"Anal. Chim. Acta"}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267014012926?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267014012926?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:02:32Z","timestamp":1757703752000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267014012926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":37,"alternative-id":["S0003267014012926"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2014.10.037","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantitative performance of liquid chromatography coupled to Q-Exactive high resolution mass spectrometry (HRMS) for the analysis of tetracyclines in a complex matrix","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2014.10.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}