{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T03:03:50Z","timestamp":1772507030357,"version":"3.50.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology of Taiwan","doi-asserted-by":"publisher","award":["105-2113-M-002-013"],"award-info":[{"award-number":["105-2113-M-002-013"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.aca.2017.11.041","type":"journal-article","created":{"date-parts":[[2017,11,23]],"date-time":"2017-11-23T20:00:15Z","timestamp":1511467215000},"page":"34-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Identification of potential sphingomyelin markers for the estimation of hematocrit in dried blood spots via a lipidomic strategy"],"prefix":"10.1016","volume":"1003","author":[{"given":"Hsiao-Wei","family":"Liao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Wen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-Ting","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Hua","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Hua","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2017.11.041_bib1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/clinchem\/32.1.213","article-title":"Bang,Ivar,Christian (1869-1918), founder of modern clinical microchemistry","volume":"32","author":"Schmidt","year":"1986","journal-title":"Clin. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib2","series-title":"Dried Blood Spots: Applications and Techniques","author":"Li","year":"2014"},{"key":"10.1016\/j.aca.2017.11.041_bib3","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s40262-014-0177-7","article-title":"Therapeutic drug monitoring by dried blood spot: progress to date and future directions","volume":"53","author":"Wilhelm","year":"2014","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.aca.2017.11.041_bib4","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1586\/14789450.2014.965158","article-title":"Challenges and opportunities in mass spectrometric analysis of proteins from dried blood spots","volume":"11","author":"Martin","year":"2014","journal-title":"Expert Rev. Proteomic"},{"key":"10.1016\/j.aca.2017.11.041_bib5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/bmc.1367","article-title":"Dried blood spot sampling in combination with LC-MS\/MS for quantitative analysis of small molecules","volume":"24","author":"Li","year":"2010","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.aca.2017.11.041_bib6","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.4155\/bio.15.124","article-title":"Lead screening in DBS by solid sampling high-resolution continuum source graphite furnace atomic absorption spectrometry: application to newborns and pregnant women","volume":"7","author":"Rello","year":"2015","journal-title":"Bioanalysis"},{"key":"10.1016\/j.aca.2017.11.041_bib7","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jchromb.2008.05.025","article-title":"Application of dried blood spots combined with HPLC-MS\/MS for the quantification of acetaminophen in toxicokinetic studies","volume":"870","author":"Barfield","year":"2008","journal-title":"J.\u00a0Chromatogr. B"},{"key":"10.1016\/j.aca.2017.11.041_bib8","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1021\/ac8022839","article-title":"Dried blood spots as a sample collection technique for the determination of pharmacokinetics in clinical studies: considerations for the validation of a quantitative bioanalytical method","volume":"81","author":"Spooner","year":"2009","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib9","article-title":"A\u00a0study to evaluate dried blood spot technology as a potential sample collection technique following oral administration of paracetamol in healthy human volunteers","volume":"68","author":"Ramakrishnan","year":"2009","journal-title":"Brit J. Clin. Pharm."},{"key":"10.1016\/j.aca.2017.11.041_bib10","doi-asserted-by":"crossref","DOI":"10.1007\/s40262-014-0197-3","article-title":"Therapeutic drug monitoring by dried blood spot: progress to date and future directions","volume":"53","author":"Robijns","year":"2014","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.aca.2017.11.041_bib11","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.4155\/bio.09.124","article-title":"Bioanalytical issues in patient-friendly sampling methods for therapeutic drug monitoring: focus on antiretroviral drugs","volume":"1","author":"ter Heine","year":"2009","journal-title":"Bioanalysis"},{"key":"10.1016\/j.aca.2017.11.041_bib12","doi-asserted-by":"crossref","first-page":"6538","DOI":"10.1021\/acs.analchem.6b01321","article-title":"A\u00a0novel, nondestructive, dried blood spot-based hematocrit prediction method using noncontact diffuse reflectance spectroscopy","volume":"88","author":"Capiau","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib13","doi-asserted-by":"crossref","first-page":"8489","DOI":"10.1021\/ac5022562","article-title":"Volumetric absorptive microsampling: a dried sample collection technique for quantitative bioanalysis","volume":"86","author":"Denniff","year":"2014","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib14","doi-asserted-by":"crossref","first-page":"6457","DOI":"10.1021\/acs.analchem.6b01145","article-title":"Estimation and correction of the blood volume variations of dried blood spots using a postcolumn infused-internal standard strategy with lc-electrospray ionization-MS","volume":"88","author":"Liao","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib15","doi-asserted-by":"crossref","first-page":"653","DOI":"10.4155\/bio.14.310","article-title":"A\u00a0device for dried blood microsampling in quantitative bioanalysis: overcoming the issues associated with blood hematocrit","volume":"7","author":"Spooner","year":"2015","journal-title":"Bioanalysis"},{"key":"10.1016\/j.aca.2017.11.041_bib16","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.4155\/bio.13.170","article-title":"The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium","volume":"5","author":"de Vries","year":"2013","journal-title":"Bioanalysis"},{"key":"10.1016\/j.aca.2017.11.041_bib17","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1021\/ac303014b","article-title":"Prediction of the hematocrit of dried blood spots via potassium measurement on a routine clinical chemistry analyzer","volume":"85","author":"Capiau","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib18","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1097\/00007691-200408000-00007","article-title":"Distribution of diazepam and nordiazepam between plasma and whole blood and the influence of hematocrit","volume":"26","author":"Jones","year":"2004","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.aca.2017.11.041_bib19","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.transproceed.2004.04.097","article-title":"Effect of hematocrit on pharmacokinetics of tacrolimus in adult living donor liver transplant recipients","volume":"36","author":"Minematsu","year":"2004","journal-title":"Transpl. P"},{"key":"10.1016\/j.aca.2017.11.041_bib20","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.4155\/bio.14.151","article-title":"Current strategies for coping with the hematocrit problem in dried blood spot analysis","volume":"6","author":"De Kesel","year":"2014","journal-title":"Bioanalysis"},{"key":"10.1016\/j.aca.2017.11.041_bib21","doi-asserted-by":"crossref","first-page":"8779","DOI":"10.1021\/ac202321q","article-title":"Method of applying internal standard to dried matrix spot samples for use in quantitative bioanalysis","volume":"83","author":"Abu-Rabie","year":"2011","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib22","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.1021\/acs.analchem.5b00908","article-title":"Investigation of different approaches to incorporating internal standard in DBS quantitative bioanalytical workflows and their effect on nullifying hematocrit-based assay bias","volume":"87","author":"Abu-Rabie","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib23","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s40262-014-0177-7","article-title":"Therapeutic drug monitoring by dried blood spot: progress to date and future directions","volume":"53","author":"Wilhelm","year":"2014","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.aca.2017.11.041_bib24","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1373\/clinchem.2016.263053","article-title":"Measurement of hematocrit in dried blood spots using near-infrared spectroscopy: robust, fast, and nondestructive","volume":"62","author":"Oostendorp","year":"2016","journal-title":"Clin. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib25","doi-asserted-by":"crossref","first-page":"6749","DOI":"10.1007\/s00216-014-8114-z","article-title":"Potassium-based algorithm allows correction for the hematocrit bias in quantitative analysis of caffeine and its major metabolite in dried blood spots","volume":"406","author":"De Kesel","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib26","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/mas.20023","article-title":"Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples","volume":"24","author":"Han","year":"2005","journal-title":"Mass Spectrom. Rev."},{"key":"10.1016\/j.aca.2017.11.041_bib27","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2012.0854","article-title":"An in\u00a0vivo ratio control mechanism for phospholipid homeostasis: evidence from lipidomic studies","volume":"10","author":"Dymond","year":"2012","journal-title":"J.\u00a0R. Soc. Interface"},{"key":"10.1016\/j.aca.2017.11.041_bib28","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/abbs\/gmt155","article-title":"Role of plasma membrane lipid composition on cellular homeostasis: learning from cell line models expressing fatty acid desaturases","volume":"46","author":"Jaureguiberry","year":"2014","journal-title":"Acta Bioch Bioph Sin."},{"key":"10.1016\/j.aca.2017.11.041_bib29","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/(SICI)1097-0231(19990630)13:12<1175::AID-RCM639>3.0.CO;2-0","article-title":"The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds","volume":"13","author":"Bonfiglio","year":"1999","journal-title":"Rapid Commun. Mass Sp."},{"key":"10.1016\/j.aca.2017.11.041_bib30","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1002\/rcm.4121","volume":"23","author":"Xia","year":"2009","journal-title":"Rapid Commun. Mass Sp."},{"key":"10.1016\/j.aca.2017.11.041_bib31","doi-asserted-by":"crossref","first-page":"5837","DOI":"10.1021\/acs.analchem.5b01460","article-title":"Near-complete structural characterization of phosphatidylcholines using electron impact excitation of ions from organics","volume":"87","author":"Campbell","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib32","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/nrd1776","article-title":"The emerging field of lipidomics","volume":"4","author":"Wenk","year":"2005","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.aca.2017.11.041_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/nm.3466","article-title":"Plasma phospholipids identify antecedent memory impairment in older adults","volume":"20","author":"Mapstone","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.aca.2017.11.041_bib34","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-015-1995-1","article-title":"Serum lipidomic profiling as a useful tool for screening potential biomarkers of hepatitis B-related hepatocellular carcinoma by ultraperformance liquid chromatography-mass spectrometry","volume":"15","author":"Passos-Castilho","year":"2015","journal-title":"Bmc Cancer"},{"key":"10.1016\/j.aca.2017.11.041_bib35","article-title":"Integration of lipidomics and transcriptomics unravels aberrant lipid metabolism and defines cholesteryl oleate as potential biomarker of prostate cancer","volume":"6","author":"Li","year":"2016","journal-title":"Sci. Rep-Uk"},{"key":"10.1016\/j.aca.2017.11.041_bib36","article-title":"Identification of salivary metabolomic biomarkers for oral cancer screening","volume":"6","author":"Ishikawa","year":"2016","journal-title":"Sci. Rep-Uk"},{"key":"10.1016\/j.aca.2017.11.041_bib37","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1002\/rcm.1737","article-title":"Rapid and selective identification of molecular species in phosphatidylcholine and sphingomyelin by conditional neutral loss scanning and MS3","volume":"18","author":"Houjou","year":"2004","journal-title":"Rapid Commun. Mass Sp."},{"key":"10.1016\/j.aca.2017.11.041_bib38","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S1044-0305(99)00150-6","article-title":"Structural determination of sphingomyelin by tandem mass spectrometry with electrospray ionization","volume":"11","author":"Hsu","year":"2000","journal-title":"J.\u00a0Am. Soc. Mass Spectr."},{"key":"10.1016\/j.aca.2017.11.041_bib39","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1007\/s00216-014-7846-0","article-title":"Tissue imaging and serum lipidomic profiling for screening potential biomarkers of thyroid tumors by matrix-assisted laser desorption\/ionization-Fourier transform ion cyclotron resonance mass spectrometry","volume":"406","author":"Guo","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.aca.2017.11.041_bib40","first-page":"2467","article-title":"Lipid profiles for HER2-positive breast cancer (retracted article. See vol. 35, pg. 6354, 2015)","volume":"33","author":"Kim","year":"2013","journal-title":"Anticancer Res."},{"key":"10.1016\/j.aca.2017.11.041_bib41","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jchromb.2015.05.012","article-title":"Prediction of fetal lung maturity using the lecithin\/sphingomyelin (L\/S) ratio analysis with a simplified sample preparation, using a commercial microtip-column combined with mass spectrometric analysis","volume":"993","author":"Kwak","year":"2015","journal-title":"J.\u00a0Chromatogr. B"}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267017313193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267017313193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T13:54:45Z","timestamp":1603374885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267017313193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":41,"alternative-id":["S0003267017313193"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2017.11.041","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of potential sphingomyelin markers for the estimation of hematocrit in dried blood spots via a lipidomic strategy","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2017.11.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}