{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T08:16:37Z","timestamp":1780647397694,"version":"3.54.1"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21471001"],"award-info":[{"award-number":["21471001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21427807"],"award-info":[{"award-number":["21427807"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21575001"],"award-info":[{"award-number":["21575001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.aca.2018.04.051","type":"journal-article","created":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T08:43:32Z","timestamp":1524473012000},"page":"99-107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["A label-free photoelectrochemical biosensor for urokinase-type plasminogen activator detection based on a g-C3N4\/CdS nanocomposite"],"prefix":"10.1016","volume":"1025","author":[{"given":"Xing-Pei","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Shuai","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-jie","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He-Lin","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Ming","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-Kang","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2018.04.051_bib1","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1007\/s10495-017-1388-9","article-title":"Urokinase plasminogen activator protects cardiac myocytes from oxidative damage and apoptosis via hOGG1 induction","volume":"22","author":"Hohensinner","year":"2017","journal-title":"Apoptosis"},{"key":"10.1016\/j.aca.2018.04.051_bib2","first-page":"7288","article-title":"Overexpression of forkhead box M1 and urokinase-type plasminogen activator in gastric cancer is associated with cancer progression and poor prognosis","volume":"14","author":"Ma","year":"2017","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.aca.2018.04.051_bib3","doi-asserted-by":"crossref","first-page":"23099","DOI":"10.18632\/oncotarget.15485","article-title":"The urokinase plasminogen activation system in gastroesophageal cancer: a systematic review and meta-analysis","volume":"8","author":"Brungs","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.aca.2018.04.051_bib4","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3389\/fneur.2017.00371","article-title":"Urokinase vs Tissue-Type Plasminogen activator for Thrombolytic evacuation of spontaneous intracerebral hemorrhage in Basal ganglia","volume":"8","author":"Li","year":"2017","journal-title":"Front. Neurol."},{"key":"10.1016\/j.aca.2018.04.051_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1074\/jbc.M117.799593","article-title":"Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors","volume":"292","author":"Stepanova","year":"2017","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib6","first-page":"1","article-title":"Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs)","volume":"12","author":"Wang","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.aca.2018.04.051_bib7","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1071\/RD16477","article-title":"Tissue-specific inhibition of urokinase-type plasminogen activator expression in the testes of mice by inducible lentiviral RNA interference causes male infertility","volume":"29","author":"Zhao","year":"2017","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.aca.2018.04.051_bib8","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1002\/2211-5463.12318","article-title":"Expression of a urokinase-type plasminogen activator during tumor growth leads to angiogenesis via galanin activation in tumor-bearing mice","volume":"7","author":"Yamamoto","year":"2017","journal-title":"Febs. Open. Bio"},{"key":"10.1016\/j.aca.2018.04.051_bib9","doi-asserted-by":"crossref","first-page":"3721","DOI":"10.1002\/nbm.3721","article-title":"Detecting in\u00a0vivo urokinase plasminogen activator activity with a catalyCEST MRI contrast agent","volume":"30","author":"Sinharay","year":"2017","journal-title":"NMR Biomed."},{"key":"10.1016\/j.aca.2018.04.051_bib10","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1523\/JNEUROSCI.1630-17.2017","article-title":"A\u00a0cross-talk between neuronal urokinase-type plasminogen activator (uPA) and astrocytic uPA receptor (uPAR) promotes astrocytic activation and synaptic recovery in the ischemic brain","volume":"37","author":"Diaz","year":"2017","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.aca.2018.04.051_bib11","doi-asserted-by":"crossref","first-page":"12633","DOI":"10.1111\/aji.12633","article-title":"2017. Multparity upregulates placental plasminogen and urokinasetype plasminogen actvator","volume":"77","author":"Cortina","year":"2017","journal-title":"Am J Report Immunol"},{"key":"10.1016\/j.aca.2018.04.051_bib12","first-page":"231","article-title":"Effect of urokinase type plasminogen activator on in\u00a0vitro bovine oocyte maturation","volume":"54","author":"Rold\u00e1n-Olarte","year":"2017","journal-title":"Reproduction"},{"key":"10.1016\/j.aca.2018.04.051_bib13","doi-asserted-by":"crossref","first-page":"10601","DOI":"10.1021\/acs.analchem.7b03146","article-title":"Visualizing breast cancer cell proliferation and invasion for assessing drug efficacy with a fluorescent nanoprobe","volume":"89","author":"Luan","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib14","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.acthis.2004.11.005","article-title":"Effects of inhibition of urokinase-type plasminogen activator (U-PA) by amiloride in the cornea and tear fluid of eyes irradiated with UVB","volume":"107","author":"\u010cejkov\u00e1","year":"2005","journal-title":"Acta. Histochem."},{"key":"10.1016\/j.aca.2018.04.051_bib15","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.snb.2017.10.157","article-title":"Photoelectrochemical apta-biosensor for zeatin detection based on graphene quantum dots improved photoactivity of graphite-like carbon nitride and streptavidin induced signal inhibition","volume":"257","author":"Wang","year":"2018","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib16","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.snb.2017.01.016","article-title":"Photoelectrochemical immunosensing platform for M. SssI methyltransferase activity analysis and inhibitor screening based on g-C3N4 and CdS quantum dots","volume":"244","author":"Wang","year":"2017","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib17","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bios.2017.04.006","article-title":"Photoelectrochemical immunosensor for methylated RNA detection based on g-C3N4\/CdS quantum dots heterojunction and Phos-tag-biotin","volume":"95","author":"Wang","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2018.04.051_bib18","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.bios.2017.04.005","article-title":"CdS: Mn quantum dot-functionalized g-C3N4 nanohybrids as signalgeneration tags for photoelectrochemical immunoassay of prostate specific antigen coupling DNAzyme concatamer with enzymatic biocatalytic precipitation","volume":"95","author":"Zhang","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2018.04.051_bib19","doi-asserted-by":"crossref","first-page":"5810","DOI":"10.1039\/C7CC01582H","article-title":"A\u00a0potentiometric resolved ratiometric photoelectrochemical aptasensor","volume":"53","author":"Zhang","year":"2017","journal-title":"Chem. Commun"},{"key":"10.1016\/j.aca.2018.04.051_bib20","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1016\/j.snb.2017.09.058","article-title":"Fe3+ doped ZnO-Ag photocatalyst for photoelectrochemical sensing platform of ultrasensitive Hg2+ detection using exonuclease III-assisted target recycling and DNAzyme-catalyzed amplification","volume":"255","author":"Zhang","year":"2017","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib21","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1021\/acs.analchem.7b04479","article-title":"Near-infrared-to-ultraviolet light-mediated photoelectrochemical aptasensing platform for cancer biomarker based on core-shell NaYF4:Yb,Tm@TiO2 upconversion microrods","volume":"90","author":"Qiu","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib22","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.snb.2017.07.078","article-title":"Quenching effect of exciton energy transfer from CdS: Mn to Au nanoparticles: a highly efficient photoelectrochemical strategy for microRNA-21 detection, Sens","volume":"254","author":"Wang","year":"2018","journal-title":"Actuator B Chem"},{"key":"10.1016\/j.aca.2018.04.051_bib23","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.bios.2017.10.032","article-title":"A\u00a0highly sensitive VEGF165 photoelectrochemical biosensor fabricated by assembly of aptamer bridged DNA networks","volume":"101","author":"Da","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2018.04.051_bib24","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.snb.2017.07.149","article-title":"A\u00a0cathodic \u201csignal-on\u201d photoelectrochemical sensor for Hg2+ detection based on ion-exchange with ZnS quantum dots","volume":"254","author":"Wang","year":"2018","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib25","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.bios.2017.04.030","article-title":"Principles and applications of photoelectrochemical sensing strategies based on biofunctionalized nanostructures","volume":"96","author":"Zang","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2018.04.051_bib26","doi-asserted-by":"crossref","first-page":"9600","DOI":"10.1039\/C7TB02354E","article-title":"Bismuth ferrite-based photoactive materials for the photoelectrochemical detection of disease biomarkers coupled with multifunctional mesoporous silica nanoparticles","volume":"5","author":"Zhou","year":"2017","journal-title":"J.\u00a0Mater. Chem. B"},{"key":"10.1016\/j.aca.2018.04.051_bib27","doi-asserted-by":"crossref","first-page":"4507","DOI":"10.1039\/C6CP08066A","article-title":"Assembly of g-C3N4-based type II and Z-scheme heterojunction anodes with improved charge separation for photoelectrojunction water oxidation","volume":"19","author":"Wang","year":"2017","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.aca.2018.04.051_bib28","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.apsusc.2016.10.203","article-title":"Fabrication and photoelectrochemical properties of silicon nanowires\/g-C3N4 core\/shell arrays","volume":"396","author":"Chen","year":"2017","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.aca.2018.04.051_bib29","doi-asserted-by":"crossref","first-page":"3723","DOI":"10.1021\/acsami.7b13557","article-title":"Spatial-resolved photoelectrochemical biosensing array based on a CdS@g-C3N4 heterojunction: a universal immunosensing platform for accurate detection","volume":"10","author":"Dong","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.aca.2018.04.051_bib30","first-page":"393","article-title":"Enhanced gas separation performance of mixed matrix membranes from graphitic carbon nitride nanosheets and polymers of intrinsic microporosity","volume":"378","author":"Tian","year":"2016","journal-title":"J.\u00a0Membr. Sci."},{"key":"10.1016\/j.aca.2018.04.051_bib31","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.bios.2016.12.059","article-title":"A\u00a0bio-chemical application of N-GQDs and g-C3N4 QDs sensitized TiO2 nanopillars for the quantitative detection of pcDNA3-HBV","volume":"91","author":"Pang","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2018.04.051_bib32","doi-asserted-by":"crossref","first-page":"12340","DOI":"10.1021\/acs.analchem.5b03721","article-title":"Facile preparation of exposed {001} facet TiO2 nanobelts coated by monolayer carbon and its highperformance photocatalytic activity","volume":"87","author":"Zhao","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib33","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1039\/C7CC08132D","article-title":"An in situ electron donor consumption strategy for photoelectrochemical biosensing of proteins based on ternary Bi2S3\/Ag2S\/TiO2 NT arrays","volume":"54","author":"Wang","year":"2018","journal-title":"Chem. Commun"},{"key":"10.1016\/j.aca.2018.04.051_bib34","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1002\/celc.201700035","article-title":"Label-free electrochemiluminescence aptasensor for highly sensitive detection of acetylcholinesterase based on Au nanoparticles functionalized g-C3N4 nanohybrid","volume":"4","author":"Liu","year":"2017","journal-title":"ChemElectroChem"},{"key":"10.1016\/j.aca.2018.04.051_bib35","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.snb.2017.10.065","article-title":"Graphite-like g-C3N4-F127-Au nanosheets used for sensitive monitoring of heat shock protein 90","volume":"256","author":"Sun","year":"2017","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib36","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.apcata.2017.09.015","article-title":"Direct catalytic hydroxylation of benzene to phenol catalyzed by vanadia supported on exfoliated graphitic carbon nitride","volume":"549","author":"Xu","year":"2018","journal-title":"Appl. Catal. A-Gen"},{"key":"10.1016\/j.aca.2018.04.051_bib37","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1002\/smll.201303827","article-title":"Proton-functionalized two-dimensional graphitic carbon nitride nanosheet: an excellent metal-\/label-free biosensing platform","volume":"10","author":"Ma","year":"2014","journal-title":"Small"},{"key":"10.1016\/j.aca.2018.04.051_bib38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jphotobiol.2016.12.034","article-title":"Ru-dye grafted CdS and reduced graphene oxide Ru\/CdS\/rGO composite: an efficient and photo tuneable electrode material for solid state dye sensitized polymer solar cells","volume":"167","author":"Nosheen","year":"2017","journal-title":"J.\u00a0Photochem. Photobiol., B"},{"key":"10.1016\/j.aca.2018.04.051_bib39","doi-asserted-by":"crossref","first-page":"5784","DOI":"10.1039\/C7NJ01132F","article-title":"Highly sensitive and selective detection of picric acid using a one pot biomolecule inspired polyindole\/CdS nanocomposite","volume":"41","author":"Faraz","year":"2017","journal-title":"New J. Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib40","doi-asserted-by":"crossref","first-page":"3929","DOI":"10.1016\/j.arabjc.2014.05.033","article-title":"Synthesis of water soluble CdS nanoparticles and study of their DNA damage activity","volume":"10","author":"Prasad","year":"2014","journal-title":"Arab. J. Chem."},{"key":"10.1016\/j.aca.2018.04.051_bib41","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/j.ijhydene.2012.10.116","article-title":"In-situ growth of CdS quantum dots on g-C3N4 nanosheets for highly efficient photocatalytic hydrogen generation under visible light irradiation","volume":"38","author":"Cao","year":"2013","journal-title":"Int. J. Hydrogen Energy"},{"key":"10.1016\/j.aca.2018.04.051_bib42","doi-asserted-by":"crossref","first-page":"13793","DOI":"10.1039\/C7DT02929B","article-title":"Noble-metal-free nickel phosphide modified CdS\/C3N4 nanorods for dramatically enhanced photocatalytic hydrogen evolution under visible light irradiation","volume":"46","author":"Wu","year":"2017","journal-title":"Dalton Trans."},{"key":"10.1016\/j.aca.2018.04.051_bib43","doi-asserted-by":"crossref","first-page":"10840","DOI":"10.1021\/acssuschemeng.7b02774","article-title":"Exciton\u2212plasmon interactions between CdS@g-C3N4 heterojunction and Au@Ag nanoparticles coupled with DNAase-triggered signal amplification: toward highly sensitive photoelectrochemical bioanalysis of microRNA","volume":"5","author":"Dong","year":"2017","journal-title":"ACS Sustain. Chem. Eng."},{"key":"10.1016\/j.aca.2018.04.051_bib44","doi-asserted-by":"crossref","first-page":"19182","DOI":"10.1021\/acs.jpcc.7b04640","article-title":"Fluorinated surface of carbon nanotube buckypaper for uniform growth of CdS nanoparticles","volume":"121","author":"Fedoseeva","year":"2017","journal-title":"J.\u00a0Phys. Chem. C"},{"key":"10.1016\/j.aca.2018.04.051_bib45","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.apsusc.2017.07.139","article-title":"Fabrication of Bi modified Bi2S3 pillared g-C3N4 photocatalyst and its efficient photocatalytic reduction and oxidation performances","volume":"426","author":"Chen","year":"2017","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.aca.2018.04.051_bib46","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.bios.2014.03.011","article-title":"A\u00a0new signal amplification strategy of photoelectrochemical immunoassay for highly sensitive interleukin-6 detection based on TiO2\/CdS\/CdSe dual co-sensitized structure","volume":"59","author":"Fan","year":"2014","journal-title":"Biosens. Bioelectron."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267018305373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267018305373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T04:04:46Z","timestamp":1545365086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267018305373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":46,"alternative-id":["S0003267018305373"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2018.04.051","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A label-free photoelectrochemical biosensor for urokinase-type plasminogen activator detection based on a g-C3N4\/CdS nanocomposite","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2018.04.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}