{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T22:01:10Z","timestamp":1775772070258,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["2020R1A6A1A06046728"],"award-info":[{"award-number":["2020R1A6A1A06046728"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2021R1A2B5B02002412"],"award-info":[{"award-number":["2021R1A2B5B02002412"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.aca.2022.340152","type":"journal-article","created":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T12:20:45Z","timestamp":1657369245000},"page":"340152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Feasibility for SERS-based discrimination of gallbladder cancer from polyp by indirect recognition of components in bile"],"prefix":"10.1016","volume":"1221","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1643-2081","authenticated-orcid":false,"given":"Thu Thuy","family":"Bui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1316-4939","authenticated-orcid":false,"given":"Tung Duy","family":"Vu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eunjin","family":"Jang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geum-sook","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongho","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0129-6571","authenticated-orcid":false,"given":"Hoeil","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.aca.2022.340152_bib1","doi-asserted-by":"crossref","first-page":"8159","DOI":"10.1021\/acs.analchem.0c00275","article-title":"Feasibility of voltage-applied SERS measurement of bile juice as an effective analytical scheme to enhance discrimination between gall bladder (GB) polyp and GB cancer","volume":"92","author":"Vu","year":"2020","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib2","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0016-5085(78)90358-X","article-title":"Unconjugated bilirubin, and the hydrolysis of conjugated bilirubin, in gallbladder bile of patients with cholelithiasis","volume":"74","author":"Boonyapisit","year":"1978","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib3","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.colsurfa.2006.02.009","article-title":"Molecular dynamics simulations of spontaneous bile salt aggregation","volume":"280","author":"Warren","year":"2006","journal-title":"Colloids Surf. A Physicochem. Eng. Asp."},{"key":"10.1016\/j.aca.2022.340152_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.129238","article-title":"Pretreatment-free SERS analysis of raw bile juice for identification of gall bladder disease using paper-coupled Au nanodendrite-encaged nickel foam","volume":"329","author":"Vu","year":"2021","journal-title":"Sensor. Actuator. B Chem."},{"issue":"10","key":"10.1016\/j.aca.2022.340152_bib5","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1016\/j.patrec.2005.01.003","article-title":"A divide-and-conquer approach to the pairwise opposite class-nearest neighbor (POC-NN) algorithm","volume":"26","author":"Raicharoen","year":"2005","journal-title":"Pattern Recogn. Lett."},{"issue":"5","key":"10.1016\/j.aca.2022.340152_bib6","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1109\/TNNLS.2017.2673241","article-title":"Efficient kNN classification with different numbers of nearest neighbors","volume":"29","author":"Zhang","year":"2018","journal-title":"IEEE Transact. Neural Networks Learn. Syst."},{"issue":"4","key":"10.1016\/j.aca.2022.340152_bib7","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1021\/cr9502357","article-title":"Formation and structure of self-assembled monolayers","volume":"96","author":"Ulman","year":"1996","journal-title":"Chem. Rev."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib8","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1021\/acs.analchem.5b03588","article-title":"Revealing intermolecular interaction and surface restructuring of an aromatic thiol assembling on Au(111) by tip-enhanced Raman spectroscopy","volume":"88","author":"Wang","year":"2016","journal-title":"Anal. Chem."},{"issue":"5","key":"10.1016\/j.aca.2022.340152_bib9","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1039\/b907301a","article-title":"Self-assembled monolayers of thiols and dithiols on gold: new challenges for a well-known system","volume":"39","author":"Vericat","year":"2010","journal-title":"Chem. Soc. Rev."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib10","doi-asserted-by":"crossref","first-page":"4348","DOI":"10.1038\/ncomms5348","article-title":"Quantifying thiol\u2013gold interactions towards the efficient strength control","volume":"5","author":"Xue","year":"2014","journal-title":"Nat. Commun."},{"issue":"8","key":"10.1016\/j.aca.2022.340152_bib11","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1039\/C0JM02696D","article-title":"Lateral interactions at functional monolayers","volume":"21","author":"Hsu","year":"2011","journal-title":"J. Mater. Chem."},{"issue":"2","key":"10.1016\/j.aca.2022.340152_bib12","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1021\/ac034800e","article-title":"Parametric time warping","volume":"76","author":"Eilers","year":"2004","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.aca.2010.08.033","article-title":"Asymmetric least squares for multiple spectra baseline correction","volume":"683","author":"Peng","year":"2010","journal-title":"Anal. Chim. Acta"},{"issue":"6","key":"10.1016\/j.aca.2022.340152_bib14","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1152\/ajplegacy.1959.197.6.1322","article-title":"Sodium glucuronate and glucuronolactone in bilirubin conjugation and formation of borneol glucuronide","volume":"197","author":"Driscoll","year":"1959","journal-title":"Am. J. Physiol."},{"issue":"3","key":"10.1016\/j.aca.2022.340152_bib15","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1042\/bj1190387","article-title":"Bilirubin conjugates of human bile. Isolation of phenylazo derivatives of bile bilirubin","volume":"119","author":"Kuenzle","year":"1970","journal-title":"Biochem. J."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib16","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s40168-021-01101-1","article-title":"Review: microbial transformations of human bile acids","volume":"9","author":"Guzior","year":"2021","journal-title":"Microbiome"},{"issue":"7","key":"10.1016\/j.aca.2022.340152_bib17","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1002\/ijc.27777","article-title":"Risk factors for gallbladder cancer: a case\u2013control study","volume":"132","author":"Jain","year":"2013","journal-title":"Int. J. Cancer"},{"issue":"6","key":"10.1016\/j.aca.2022.340152_bib18","doi-asserted-by":"crossref","first-page":"817","DOI":"10.3349\/ymj.2006.47.6.817","article-title":"Bile acid analysis in biliary tract cancer","volume":"47","author":"Park","year":"2006","journal-title":"Yonsei Med. J."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib19","first-page":"4","article-title":"Bile acid physiology","volume":"16","author":"Di Ciaula","year":"2018","journal-title":"Ann. Hepatol."},{"issue":"12","key":"10.1016\/j.aca.2022.340152_bib20","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1136\/jcp.2010.080713","article-title":"Strong cytoplasmic expression of COX2 at the invasive fronts of gallbladder cancer is associated with a poor prognosis","volume":"63","author":"Kim","year":"2010","journal-title":"J. Clin. Pathol."},{"issue":"6","key":"10.1016\/j.aca.2022.340152_bib21","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1093\/annonc\/mdu006","article-title":"A genetic model for gallbladder carcinogenesis and its dissemination","volume":"25","author":"Barreto","year":"2014","journal-title":"Ann. Oncol."},{"issue":"3","key":"10.1016\/j.aca.2022.340152_bib22","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.rgmx.2013.02.003","article-title":"The role of the gallbladder in humans","volume":"78","author":"Turumin","year":"2013","journal-title":"Rev. Gastroenterol. M\u00e9xico"},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib23","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/s41467-019-13615-2","article-title":"Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting","volume":"11","author":"Kim","year":"2020","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib24","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.apsusc.2004.10.139","article-title":"Structure of mercaptoalcohol self-assembled monolayers on Au(111)","volume":"244","author":"Tsukamoto","year":"2005","journal-title":"Appl. Surf. Sci."},{"issue":"14","key":"10.1016\/j.aca.2022.340152_bib25","doi-asserted-by":"crossref","first-page":"6203","DOI":"10.1021\/la0605891","article-title":"Assembly dynamics and detailed structure of 1-propanethiol monolayers on Au(111) surfaces observed real time by in situ STM","volume":"22","author":"Zhang","year":"2006","journal-title":"Langmuir"},{"issue":"4","key":"10.1016\/j.aca.2022.340152_bib26","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1116\/1.582477","article-title":"Insertion process and electrical conduction of conjugated molecules in n-alkanethiol self-assembled monolayers on Au(111)","volume":"18","author":"Ishida","year":"2000","journal-title":"J. Vac. Sci. Technol."},{"issue":"12","key":"10.1016\/j.aca.2022.340152_bib27","doi-asserted-by":"crossref","first-page":"3279","DOI":"10.1021\/la971121o","article-title":"Corrosion passivation of gold by n-alkanethiol self-assembled monolayers: effect of chain length and end group","volume":"14","author":"Zamborini","year":"1998","journal-title":"Langmuir"},{"issue":"5","key":"10.1016\/j.aca.2022.340152_bib28","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/jrs.703","article-title":"Influence of electrolytes on the structure of cysteamine monolayer on silver studied by surface-enhanced Raman scattering","volume":"32","author":"Michota","year":"2001","journal-title":"J. Raman Spectrosc."},{"issue":"11","key":"10.1016\/j.aca.2022.340152_bib29","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1002\/jrs.1247","article-title":"Surface-enhanced Raman scattering of 3-mercaptopropionic acid adsorbed on a colloidal silver surface","volume":"35","author":"Castro","year":"2004","journal-title":"J. Raman Spectrosc."},{"issue":"1","key":"10.1016\/j.aca.2022.340152_bib30","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.vibspec.2007.08.005","article-title":"In situ SERS studies on the adsorption of tyrosinase on bare and alkanethiol-modified silver substrates","volume":"46","author":"Kudelski","year":"2008","journal-title":"Vib. Spectrosc."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267022007231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267022007231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:54:26Z","timestamp":1757706866000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267022007231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":30,"alternative-id":["S0003267022007231"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2022.340152","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Feasibility for SERS-based discrimination of gallbladder cancer from polyp by indirect recognition of components in bile","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2022.340152","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"340152"}}