{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:57:00Z","timestamp":1792652220538,"version":"4.5.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"am","delay-in-days":326,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01GM135486"],"award-info":[{"award-number":["R01GM135486"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.aca.2023.340956","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T02:40:24Z","timestamp":1675996824000},"page":"340956","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"special_numbering":"C","title":["Ultra-trace SERS detection of cocaine and heroin using bimetallic gold\u2013silver nanostars (BGNS-Ag)"],"prefix":"10.1016","volume":"1251","author":[{"given":"Supriya","family":"Atta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuan","family":"Vo-Dinh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2023.340956_bib1","unstructured":"N.C.f.I.P.a.C. Centers for Disease Control and Prevention, Cocaine and Psychostimulant-Involved Overdose Deaths Disproportionately Affect Racial and Ethnic Minority Groups."},{"key":"10.1016\/j.aca.2023.340956_bib2","series-title":"U.S. Overdose Deaths in 2021 Increased Half as Much as in 2020 \u2013 but Are Still up 15%","year":"2022"},{"key":"10.1016\/j.aca.2023.340956_bib3","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jpba.2007.11.025","article-title":"On-site screening and GC\u2013MS analysis of cocaine and heroin metabolites in body-packers urine","volume":"48","author":"Marchei","year":"2008","journal-title":"J. Pharmaceut. Biomed. Anal."},{"key":"10.1016\/j.aca.2023.340956_bib4","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1002\/dta.2771","article-title":"Hitting the Jackpot \u2013 development of gas chromatography\u2013mass spectrometry (GC\u2013MS) and other rapid screening methods for the analysis of 18 fentanyl-derived synthetic opioids","volume":"12","author":"Gilbert","year":"2020","journal-title":"Drug Test. Anal."},{"key":"10.1016\/j.aca.2023.340956_bib5","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1021\/ac960060g","article-title":"Analysis of cocaine, benzoylecgonine, and cocaethylene in urine by HPLC with diode array detection","volume":"68","author":"Clauwaert","year":"1996","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib6","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.jpba.2008.02.007","article-title":"Quantitative analysis of cocaine in human hair by HPLC with fluorescence detection","volume":"48","author":"Mercolini","year":"2008","journal-title":"J. Pharmaceut. Biomed. Anal."},{"key":"10.1016\/j.aca.2023.340956_bib7","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1002\/dta.2515","article-title":"Microfluidic electrochemical immunosensor for the trace analysis of cocaine in water and body fluids","volume":"11","author":"Abdelshafi","year":"2019","journal-title":"Drug Test. Anal."},{"key":"10.1016\/j.aca.2023.340956_bib8","doi-asserted-by":"crossref","first-page":"4592","DOI":"10.1039\/C7AY01523B","article-title":"Development of competitive \u2018pseudo\u2019-ELISA assay for measurement of cocaine and its metabolites using molecularly imprinted polymer nanoparticles","volume":"9","author":"Garcia","year":"2017","journal-title":"Anal. Methods"},{"key":"10.1016\/j.aca.2023.340956_bib9","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1021\/acsnano.9b04224","article-title":"Present and future of surface-enhanced Raman scattering","volume":"14","author":"Langer","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.aca.2023.340956_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/bios9020057","article-title":"A review on surface-enhanced Raman scattering","volume":"9","author":"Pilot","year":"2019","journal-title":"Biosensors"},{"key":"10.1016\/j.aca.2023.340956_bib11","doi-asserted-by":"crossref","first-page":"11517","DOI":"10.1039\/D1TC02134F","article-title":"Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates","volume":"9","author":"Li","year":"2021","journal-title":"J. Mater. Chem. C"},{"key":"10.1016\/j.aca.2023.340956_bib12","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0165-9936(98)00069-7","volume":"17","author":"Vo-Dinh","year":"1998","journal-title":"TrAC, Trends Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib13","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1109\/JSEN.2005.850993","article-title":"Surface-enhanced Raman scattering detection of chemical and biological agent simulants","volume":"5","author":"Yan","year":"2005","journal-title":"IEEE Sensor. J."},{"key":"10.1016\/j.aca.2023.340956_bib14","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.bios.2016.01.073","article-title":"Sensitive DNA detection and SNP discrimination using ultrabright SERS nanorattles and magnetic beads for malaria diagnostics","volume":"81","author":"Ngo","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2023.340956_bib15","doi-asserted-by":"crossref","first-page":"12126","DOI":"10.1039\/c3nr03762b","article-title":"Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics","volume":"5","author":"Liu","year":"2013","journal-title":"Nanoscale"},{"key":"10.1016\/j.aca.2023.340956_bib16","doi-asserted-by":"crossref","first-page":"8606","DOI":"10.1038\/s41598-017-09116-1","article-title":"Synergistic immuno photothermal nanotherapy (SYMPHONY) for the treatment of unresectable and metastatic cancers","volume":"7","author":"Liu","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.aca.2023.340956_bib17","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jphotochemrev.2014.09.001","article-title":"Recent approaches toward creation of hot spots for SERS detection","volume":"21","author":"Shiohara","year":"2014","journal-title":"J. Photochem. Photobiol. C Photochem. Rev."},{"key":"10.1016\/j.aca.2023.340956_bib18","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1021\/acsphotonics.6b00786","article-title":"Optimization of nanoparticle-based SERS substrates through large-scale realistic simulations","volume":"4","author":"Sol\u00eds","year":"2017","journal-title":"ACS Photonics"},{"key":"10.1016\/j.aca.2023.340956_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2019.00706","article-title":"A surface-enhanced Raman spectral library of important drugs associated with point-of-care and field applications","volume":"7","author":"Farquharson","year":"2019","journal-title":"Front. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.talanta.2018.08.032","article-title":"Development of surface-enhanced Raman spectroscopy application for determination of illicit drugs: towards a practical sensor","volume":"191","author":"Yu","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2023.340956_bib21","doi-asserted-by":"crossref","first-page":"9373","DOI":"10.1021\/acs.analchem.1c00792","article-title":"Rapid SERS quantification of trace fentanyl laced in recreational drugs with a portable Raman module","volume":"93","author":"Wang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib22","doi-asserted-by":"crossref","first-page":"12678","DOI":"10.1021\/acs.analchem.8b02909","article-title":"Detection and quantitation of trace fentanyl in heroin by surface-enhanced Raman spectroscopy","volume":"90","author":"Haddad","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib23","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1002\/elps.201900004","article-title":"Elucidating fentanyls differentiation from morphines in chemical and biological samples with surface-enhanced Raman spectroscopy","volume":"40","author":"Wang","year":"2019","journal-title":"Electrophoresis"},{"key":"10.1016\/j.aca.2023.340956_bib24","doi-asserted-by":"crossref","first-page":"4850","DOI":"10.1021\/acs.analchem.2c00157","article-title":"Gold-trisoctahedra-coated capillary-based SERS platform for microsampling and sensitive detection of trace fentanyl","volume":"94","author":"Zhang","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib25","doi-asserted-by":"crossref","first-page":"5449","DOI":"10.1039\/C9AN01087D","article-title":"Detection of codeine and fentanyl in saliva, blood plasma and whole blood in 5-minutes using a SERS flow-separation strip","volume":"144","author":"Shende","year":"2019","journal-title":"Analyst"},{"key":"10.1016\/j.aca.2023.340956_bib26","doi-asserted-by":"crossref","first-page":"5263","DOI":"10.1021\/acs.analchem.5b00328","article-title":"Self-assembled nanocube-based plasmene nanosheets as soft surface-enhanced Raman scattering substrates toward direct quantitative drug identification on surfaces","volume":"87","author":"Si","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib27","doi-asserted-by":"crossref","first-page":"4540","DOI":"10.1021\/acs.langmuir.9b00358","article-title":"Role of TiO2 nanoparticles and UV irradiation in the enhancement of SERS spectra to improve levamisole and cocaine detection on Au substrates","volume":"35","author":"Skoup\u00e1","year":"2019","journal-title":"Langmuir"},{"key":"10.1016\/j.aca.2023.340956_bib28","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1039\/b9nr00059c","article-title":"Label-free SERS detection of relevant bioanalytes on silver-coated carbon nanotubes: the case of cocaine","volume":"1","author":"Sanles-Sobrido","year":"2009","journal-title":"Nanoscale"},{"key":"10.1016\/j.aca.2023.340956_bib29","doi-asserted-by":"crossref","first-page":"9500","DOI":"10.1021\/acs.analchem.5b02899","article-title":"Portable kit for identification and detection of drugs in human urine using surface-enhanced Raman spectroscopy","volume":"87","author":"Han","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib30","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1039\/C2AN36116G","article-title":"Inkjet-printed paper-based SERS dipsticks and swabs for trace chemical detection","volume":"138","author":"Yu","year":"2013","journal-title":"Analyst"},{"key":"10.1016\/j.aca.2023.340956_bib31","article-title":"Picoanalysis of drugs in biofluids with quantitative label-free surface-enhanced Raman spectroscopy","volume":"14","author":"Turzhitsky","year":"2018","journal-title":"Small"},{"key":"10.1016\/j.aca.2023.340956_bib32","doi-asserted-by":"crossref","first-page":"3340","DOI":"10.1039\/D2AN00794K","article-title":"Ultra-high SERS detection of consumable coloring agents using plasmonic gold nanostars with high aspect-ratio spikes","volume":"147","author":"Atta","year":"2022","journal-title":"Analyst"},{"key":"10.1016\/j.aca.2023.340956_bib33","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1016\/j.chempr.2018.06.004","article-title":"TiO2 on gold nanostars enhances photocatalytic water reduction in the near-infrared regime","volume":"4","author":"Atta","year":"2018","journal-title":"Chem"},{"key":"10.1016\/j.aca.2023.340956_bib34","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1039\/C8FD00152A","article-title":"Enhancing hot electron generation and injection in the near infrared via rational design and controlled synthesis of TiO2\u2013gold nanostructures","volume":"214","author":"Atta","year":"2019","journal-title":"Faraday Discuss"},{"key":"10.1016\/j.aca.2023.340956_bib35","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1021\/acsphotonics.9b01418","article-title":"Optimizing the geometry of photoacoustically active gold nanoparticles for biomedical imaging","volume":"7","author":"Garc\u00eda-\u00c1lvarez","year":"2020","journal-title":"ACS Photonics"},{"key":"10.1016\/j.aca.2023.340956_bib36","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1039\/C6PY00465B","article-title":"Effect of gold nanoparticle shapes for phototherapy and drug delivery","volume":"7","author":"Adnan","year":"2016","journal-title":"Polym. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib37","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/cnma.201900459","article-title":"Highly tunable growth and etching of silica shells on surfactant-free gold nanostars","volume":"6","author":"Atta","year":"2020","journal-title":"ChemNanoMat"},{"key":"10.1016\/j.aca.2023.340956_bib38","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1039\/C8NR07615D","article-title":"Understanding the role of AgNO3 concentration and seed morphology in the achievement of tunable shape control in gold nanostars","volume":"11","author":"Atta","year":"2019","journal-title":"Nanoscale"},{"key":"10.1016\/j.aca.2023.340956_bib39","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1021\/ac302510g","article-title":"Quantitative surface-enhanced resonant Raman scattering multiplexing of biocompatible gold nanostars for in vitro and ex vivo detection","volume":"85","author":"Yuan","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.340956_bib40","doi-asserted-by":"crossref","first-page":"3708","DOI":"10.1021\/jp4091393","article-title":"Development of hybrid silver-coated gold nanostars for nonaggregated surface-enhanced Raman scattering","volume":"118","author":"Fales","year":"2014","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.aca.2023.340956_bib41","doi-asserted-by":"crossref","first-page":"12562","DOI":"10.1021\/acsanm.2c02234","article-title":"Bimetallic gold nanostars having high aspect ratio spikes for sensitive surface-enhanced Raman scattering sensing","volume":"5","author":"Atta","year":"2022","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.aca.2023.340956_bib42","series-title":"Interface Engineering of Gold Nanostars for Biomedical Applications, World Scientific Reference on Plasmonic Nanomaterials","first-page":"21","author":"Fabris","year":"2021"},{"key":"10.1016\/j.aca.2023.340956_bib43","doi-asserted-by":"crossref","first-page":"20749","DOI":"10.1021\/acs.jpcc.6b01949","article-title":"Shaping gold nanostar electric fields for surface-enhanced Raman spectroscopy enhancement via silica coating and selective etching","volume":"120","author":"Atta","year":"2016","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.aca.2023.340956_bib44","doi-asserted-by":"crossref","first-page":"18662","DOI":"10.1039\/C9NR06533D","article-title":"Colloidal plasmonic nanostar antennas with wide range resonance tunability","volume":"11","author":"Tsoulos","year":"2019","journal-title":"Nanoscale"},{"key":"10.1016\/j.aca.2023.340956_bib45","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.saa.2018.12.001","article-title":"The synthesis of Ag-coated tetrapod gold nanostars and the improvement of surface-enhanced Raman scattering","volume":"211","author":"Zhu","year":"2019","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2023.340956_bib46","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1002\/jrs.5963","article-title":"Porphyrin-conjugated silver-coated gold nanostars for ultrasensitive detection and multiplexing","volume":"51","author":"Benavides","year":"2020","journal-title":"J. Raman Spectrosc."},{"key":"10.1016\/j.aca.2023.340956_bib47","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.1021\/jz502349x","article-title":"Spectroelectrochemistry of silver deposition on single gold nanocrystals","volume":"5","author":"Chirea","year":"2014","journal-title":"J. Phys. Chem. Lett."},{"key":"10.1016\/j.aca.2023.340956_bib48","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.saa.2018.06.080","article-title":"Synthesis and SERS activity of super-multibranched AuAg nanostructure via silver coating-induced aggregation of nanostars","volume":"204","author":"Li","year":"2018","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2023.340956_bib49","doi-asserted-by":"crossref","DOI":"10.1088\/2040-8978\/17\/11\/114013","article-title":"Optimizing gold nanostars as a colloid-based surface-enhanced Raman scattering (SERS) substrate","volume":"17","author":"He","year":"2015","journal-title":"J. Opt."},{"key":"10.1016\/j.aca.2023.340956_bib50","doi-asserted-by":"crossref","first-page":"5149","DOI":"10.1021\/jacs.5b01426","article-title":"Label-free surface-enhanced Raman spectroscopy detection of DNA with single-base sensitivity","volume":"137","author":"Xu","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2023.340956_bib51","doi-asserted-by":"crossref","first-page":"15580","DOI":"10.1021\/ja066263w","article-title":"Surface-enhanced Raman spectroscopy (SERS) for sub-micromolar detection of DNA\/RNA mononucleotides","volume":"128","author":"Bell","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2023.340956_bib52","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1021\/acs.jpclett.9b03724","article-title":"Key role of direct adsorption on SERS sensitivity: synergistic effect among target, aggregating agent, and surface with Au or Ag colloid as surface-enhanced Raman spectroscopy substrate","volume":"11","author":"Xie","year":"2020","journal-title":"J. Phys. Chem. Lett."},{"key":"10.1016\/j.aca.2023.340956_bib53","doi-asserted-by":"crossref","first-page":"6592","DOI":"10.1021\/acsanm.9b01493","article-title":"Silver nanoparticle-based surface-enhanced Raman spectroscopy for the rapid and selective detection of trace tropane alkaloids in food","volume":"2","author":"Lu","year":"2019","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.aca.2023.340956_bib54","doi-asserted-by":"crossref","first-page":"8891","DOI":"10.1039\/C4NR02513J","article-title":"Gold nanostar substrates for SERS-based chemical sensing in the femtomolar regime","volume":"6","author":"Indrasekara","year":"2014","journal-title":"Nanoscale"},{"key":"10.1016\/j.aca.2023.340956_bib55","first-page":"1","article-title":"Rapid analysis of cocaine in saliva by surface-enhanced Raman spectroscopy","volume":"6","author":"Dana","year":"2015","journal-title":"J. Anal. Bioanal. Tech."},{"key":"10.1016\/j.aca.2023.340956_bib56","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.talanta.2016.10.101","article-title":"Designing of ordered two-dimensional gold nanoparticles film for cocaine detection in human urine using surface-enhanced Raman spectroscopy","volume":"164","author":"Meng","year":"2017","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2023.340956_bib57","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1366\/11-06310","article-title":"Detection of drugs of abuse in saliva by surface-enhanced Raman spectroscopy (SERS)","volume":"65","author":"Inscore","year":"2011","journal-title":"Appl. Spectrosc."},{"key":"10.1016\/j.aca.2023.340956_bib58","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.1039\/c3an00673e","article-title":"Chromatographic separation and detection of target analytes from complex samples using inkjet printed SERS substrates","volume":"138","author":"Yu","year":"2013","journal-title":"Analyst"},{"key":"10.1016\/j.aca.2023.340956_bib59","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.colsurfa.2018.05.068","article-title":"Gold nanorods as SERS substrate for the ultratrace detection of cocaine in non-pretreated oral fluid samples","volume":"557","author":"D'Elia","year":"2018","journal-title":"Colloids Surf. A Physicochem. Eng. Asp."},{"key":"10.1016\/j.aca.2023.340956_bib60","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2165\/00003088-200645040-00005","article-title":"Population pharmacokinetics of heroin and its major metabolites","volume":"45","author":"Rook","year":"2006","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.aca.2023.340956_bib61","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1093\/jat\/30.8.501","article-title":"Major and minor metabolites of cocaine in human plasma following controlled subcutaneous cocaine administration","volume":"30","author":"Kolbrich","year":"2006","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.aca.2023.340956_bib62","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/jat\/24.7.467","article-title":"Elimination of cocaine and metabolites in plasma, saliva, and urine following repeated oral administration to human volunteers","volume":"24","author":"Jufer","year":"2000","journal-title":"J. Anal. Toxicol."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023001770?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023001770?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:56:31Z","timestamp":1757706991000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267023001770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":62,"alternative-id":["S0003267023001770"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2023.340956","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ultra-trace SERS detection of cocaine and heroin using bimetallic gold\u2013silver nanostars (BGNS-Ag)","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2023.340956","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"340956"}}