{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T21:08:22Z","timestamp":1789765702914,"version":"4.0.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of\u00a0Hunan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009020","name":"University of South China","doi-asserted-by":"publisher","award":["201RGC012"],"award-info":[{"award-number":["201RGC012"]}],"id":[{"id":"10.13039\/501100009020","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009020","name":"University of South China","doi-asserted-by":"publisher","award":["220XQD030"],"award-info":[{"award-number":["220XQD030"]}],"id":[{"id":"10.13039\/501100009020","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011220","name":"State Key Laboratory of Chemo\/Biosensing and Chemometrics","doi-asserted-by":"publisher","award":["2021013"],"award-info":[{"award-number":["2021013"]}],"id":[{"id":"10.13039\/501100011220","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011220","name":"State Key Laboratory of Chemo\/Biosensing and Chemometrics","doi-asserted-by":"publisher","award":["2021015"],"award-info":[{"award-number":["2021015"]}],"id":[{"id":"10.13039\/501100011220","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.aca.2023.341009","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T05:25:51Z","timestamp":1677648351000},"page":"341009","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"special_numbering":"C","title":["Construction of HClO activated near-infrared fluorescent probe for imaging hepatocellular carcinoma"],"prefix":"10.1016","volume":"1252","author":[{"given":"Songjiao","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peipei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8206-8783","authenticated-orcid":false,"given":"Longwei","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2023.341009_bib1","doi-asserted-by":"crossref","first-page":"6009","DOI":"10.3390\/cancers13236009","article-title":"Comparison of overall survival between surgical resection and radiofrequency ablation for hepatitis B-related hepatocellular carcinoma","volume":"13","author":"Hur","year":"2021","journal-title":"Cancers"},{"key":"10.1016\/j.aca.2023.341009_bib2","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.urolonc.2009.12.013","article-title":"Prostate cancer around the world. An overview","volume":"28","author":"Schroder","year":"2010","journal-title":"Urol. Oncol."},{"key":"10.1016\/j.aca.2023.341009_bib3","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1016\/S1470-2045(21)00602-1","article-title":"Global cancer research in the post-pandemic world","volume":"22","author":"Mukherji","year":"2021","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.aca.2023.341009_bib4","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jhep.2019.03.007","article-title":"A comprehensive study of epigenetic alterations in hepatocellular carcinoma identifies potential therapeutic targets","volume":"71","author":"Bayo","year":"2019","journal-title":"J. Hepatol."},{"key":"10.1016\/j.aca.2023.341009_bib5","first-page":"115","article-title":"Cancer statistics in China, 2015","volume":"66","author":"Chen","year":"2016","journal-title":"CA A Cancer J. Clin."},{"key":"10.1016\/j.aca.2023.341009_bib6","doi-asserted-by":"crossref","first-page":"32605","DOI":"10.1021\/acsami.9b08522","article-title":"Precise synthesis of GSH-specific fluorescent probe for hepatotoxicity assessment guided by theoretical calculation","volume":"11","author":"Chen","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.aca.2023.341009_bib7","doi-asserted-by":"crossref","first-page":"4563","DOI":"10.1039\/C4CS00051J","article-title":"Macro-\/micro-environment-sensitive chemosensing and biological imaging","volume":"43","author":"Yang","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.aca.2023.341009_bib8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nrd.2018.146","article-title":"The hepatocellular carcinoma market","volume":"18","author":"Dawkins","year":"2019","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.aca.2023.341009_bib9","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1021\/acs.accounts.9b00307","article-title":"Design principles, sensing mechanisms, and applications of highly specific fluorescent probes for HClO\/OCl(-)","volume":"52","author":"Wu","year":"2019","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.aca.2023.341009_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2019.110706","article-title":"Catalase prevents myeloperoxidase self-destruction in response to oxidative stress","volume":"197","author":"Ali","year":"2019","journal-title":"J. Inorg. Biochem."},{"key":"10.1016\/j.aca.2023.341009_bib11","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1021\/acs.analchem.7b04234","article-title":"Small-molecule fluorescent probes for imaging and detection of reactive oxygen, nitrogen, and sulfur species in biological systems","volume":"90","author":"Jiao","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.341009_bib12","doi-asserted-by":"crossref","first-page":"6035","DOI":"10.1039\/C8SC01697F","article-title":"Design of a ratiometric two-photon probe for imaging of hypochlorous acid (HClO) in wounded tissues","volume":"9","author":"Mao","year":"2018","journal-title":"Chem. Sci."},{"key":"10.1016\/j.aca.2023.341009_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.130063","article-title":"A ratiometric near-infrared fluorescent probe with a large emission peak shift for sensing and imaging hypochlorous acid","volume":"343","author":"He","year":"2021","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2023.341009_bib14","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.freeradbiomed.2010.09.006","article-title":"Oxidative stress, inflammation, and cancer: how are they linked?","volume":"49","author":"Reuter","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.aca.2023.341009_bib15","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/s41423-022-00905-x","article-title":"Role of pyroptosis in inflammation and cancer, Cell","volume":"19","author":"Wei","year":"2022","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.aca.2023.341009_bib16","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.freeradbiomed.2009.05.004","article-title":"Mitochondria and reactive oxygen species","volume":"47","author":"Kowaltowski","year":"2009","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.aca.2023.341009_bib17","doi-asserted-by":"crossref","first-page":"4598","DOI":"10.1002\/cncr.32511","article-title":"Surgery in recurrent ovarian cancer","volume":"24","author":"Sehouli","year":"2019","journal-title":"Cancer"},{"key":"10.1016\/j.aca.2023.341009_bib18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12645-016-0024-7","article-title":"Application of nanotechnology to cancer radiotherapy","volume":"7","author":"Mi","year":"2016","journal-title":"Cancer. Nanotechnol."},{"key":"10.1016\/j.aca.2023.341009_bib19","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jconrel.2017.08.034","article-title":"Chemotherapy agent-unsaturated fatty acid prodrugs and prodrug-nanoplatforms for cancer chemotherapy","volume":"264","author":"Sun","year":"2017","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.aca.2023.341009_bib20","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1097\/SLA.0000000000005647","article-title":"Long-term oncological outcomes after colorectal anastomotic leakage: a retrospective Dutch population-based study","volume":"276","author":"Arron","year":"2022","journal-title":"Ann. Surg."},{"key":"10.1016\/j.aca.2023.341009_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123699","article-title":"A dual-positive charges strategy for sensitive and quantitative detection of mitochondrial SO2 in cancer cells and tumor tissue","volume":"249","author":"Ye","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2023.341009_bib22","doi-asserted-by":"crossref","first-page":"5514","DOI":"10.1021\/acs.analchem.1c04169","article-title":"Near-Infrared fluorescent probe with large Stokes shift for imaging of hydrogen sulfide in tumor-bearing mice","volume":"94","author":"Yan","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.341009_bib23","doi-asserted-by":"crossref","first-page":"5797","DOI":"10.1021\/acs.analchem.1c05143","article-title":"Near-Infrared in and out: observation of autophagy during stroke via a lysosome-targeting two-photon viscosity-dependent probe","volume":"94","author":"Chai","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.341009_bib24","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1021\/acs.analchem.0c05118","article-title":"Highly sensitive near-infrared imaging of peroxynitrite fluxes in inflammation progress","volume":"93","author":"Wang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.341009_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.118545","article-title":"Recent development of synthetic probes for detection of hypochlorous acid\/hypochlorite","volume":"240","author":"Ma","year":"2020","journal-title":"Spectrochim. Acta. A. Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2023.341009_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.118515","article-title":"Employing an ICT-ESIPT strategy for ratiometric tracking of HClO based on sulfide oxidation reaction","volume":"239","author":"Shen","year":"2020","journal-title":"Spectrochim. Acta. A. Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2023.341009_bib27","article-title":"Engineering of reversible NIR-II redox-responsive fluorescent probes for imaging of inflammation in vivo","author":"He","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.aca.2023.341009_bib28","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1002\/asia.202100476","article-title":"Selective imaging of HClO in the liver tissue in vivo using a near-infrared hepatocyte-specific fluorescent probe","volume":"16","author":"Jia","year":"2021","journal-title":"Chem. Asian J."},{"key":"10.1016\/j.aca.2023.341009_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2020.108310","article-title":"A simple p-methylaminophenylether-based fluorescent probe for detecting native hypochlorous acid in live cells and zebrafish","volume":"177","author":"Wang","year":"2020","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.aca.2023.341009_bib30","doi-asserted-by":"crossref","first-page":"11881","DOI":"10.1021\/acs.analchem.2c02431","article-title":"Mitochondria-targeted ratiometric chemdosimeter to detect hypochlorite acid for monitoring the drug-damaged liver and kidney","volume":"94","author":"Shangguan","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.341009_bib31","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.aca.2018.10.014","article-title":"A near-infrared fluorescent probe based on photostable Si-rhodamine for imaging hypochlorous acid during lysosome-involved inflammatory response","volume":"1048","author":"Mao","year":"2019","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2023.341009_bib32","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.aca.2019.07.040","article-title":"A mitochondria-targetable two-photon fluorescent probe with a far-red to near-infrared emission for sensing hypochlorite in biosystems","volume":"1081","author":"Mao","year":"2019","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2023.341009_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2020.119326","article-title":"A lysosome-targetable two-photon excited near-infrared fluorescent probe for visualizing hypochlorous acid-involved arthritis and its treatment","volume":"249","author":"Mao","year":"2021","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2023.341009_bib34","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2116\/analsci.21P264","article-title":"A lysosome-targetable fluorescent probe based on HClO-mediated cyclization reaction for imaging of hypochlorous acid","volume":"38","author":"Wang","year":"2022","journal-title":"Anal. Sci."},{"key":"10.1016\/j.aca.2023.341009_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2021.109666","article-title":"Development of H2S and HClO dual-responsive fluorescent probe for cancer recognition","volume":"195","author":"Chen","year":"2021","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.aca.2023.341009_bib36","doi-asserted-by":"crossref","first-page":"4556","DOI":"10.1039\/D0AY01135E","article-title":"Development of a novel melatonin-modified near-infrared fluorescent probe for in vivo hepatocellular carcinoma imaging","volume":"12","author":"Huang","year":"2020","journal-title":"Anal. Methods"},{"key":"10.1016\/j.aca.2023.341009_bib37","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.1111\/bph.14116","article-title":"New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation","volume":"175","author":"Zisapel","year":"2018","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.aca.2023.341009_bib38","doi-asserted-by":"crossref","first-page":"673","DOI":"10.3390\/ijms18040673","article-title":"Effects of melatonin on liver injuries and diseases","volume":"18","author":"Zhang","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.aca.2023.341009_bib39","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.3390\/ijms19092687","article-title":"Melatonin inhibits the progression of hepatocellular carcinoma through MicroRNA let7i-3p mediated RAF1 reduction","volume":"19","author":"Wang","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.aca.2023.341009_bib40","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.3390\/cancers11071001","article-title":"Prognostic impact of melatonin receptors MT1 and MT2 in non-small cell lung cancer (NSCLC)","volume":"11","author":"Jablonska","year":"2019","journal-title":"Cancers"},{"key":"10.1016\/j.aca.2023.341009_bib41","doi-asserted-by":"crossref","first-page":"4547","DOI":"10.1002\/anie.201813648","article-title":"Release of amino- or carboxy-containing compounds triggered by HClO: application for imaging and drug design","volume":"58","author":"Wei","year":"2019","journal-title":"Angew. Chem. Int. Ed."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023002301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023002301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:43:59Z","timestamp":1762083839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267023002301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":41,"alternative-id":["S0003267023002301"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2023.341009","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Construction of HClO activated near-infrared fluorescent probe for imaging hepatocellular carcinoma","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2023.341009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"341009"}}