{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:37:46Z","timestamp":1787315866336,"version":"build-2736575974"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21735001"],"award-info":[{"award-number":["21735001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21804012"],"award-info":[{"award-number":["21804012"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.aca.2023.341356","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T05:54:06Z","timestamp":1683698046000},"page":"341356","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Monitoring H2S fluctuation during autophagic fusion of lysosomes and mitochondria using a lysosome-targeting fluorogenic probe"],"prefix":"10.1016","volume":"1265","author":[{"given":"Taoyun","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0867-6438","authenticated-orcid":false,"given":"Sheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianglan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guojiang","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1862-9926","authenticated-orcid":false,"given":"Yibo","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2023.341356_bib1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00726-010-0510-x","article-title":"Hydrogen sulfide: its production, release and functions","volume":"41","author":"Kimura","year":"2011","journal-title":"Amino Acids"},{"key":"10.1016\/j.aca.2023.341356_bib2","doi-asserted-by":"crossref","first-page":"21903","DOI":"10.1074\/jbc.R110.128363","article-title":"Redox biochemistry of hydrogen sulfide","volume":"285","author":"Kabil","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.aca.2023.341356_bib3","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1096\/fj.06-6270fje","article-title":"Hydrogen Sulfide is an endogrnous modulator of leukocyte-mediated inflammation","volume":"20","author":"Zanardo","year":"2006","journal-title":"Faseb. J."},{"key":"10.1016\/j.aca.2023.341356_bib4","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.1039\/C4CS00298A","article-title":"Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems","volume":"44","author":"Lin","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.aca.2023.341356_bib5","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.freeradbiomed.2009.09.018","article-title":"Making and working with hydrogen sulfide: the chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review, Free","volume":"47","author":"Martin","year":"2009","journal-title":"Radic. Biol. Med."},{"key":"10.1016\/j.aca.2023.341356_bib6","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1161\/CIRCRESAHA.109.199919","article-title":"Hydrogen sulfide mediates cardioprotection through Nrf2 signaling","volume":"105","author":"Calvert","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.aca.2023.341356_bib7","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.bbrc.2004.04.094","article-title":"Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol","volume":"318","author":"Geng","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.aca.2023.341356_bib8","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/s43587-021-00098-4","article-title":"Autophagy in healthy aging and disease","volume":"1","author":"Yahyah","year":"2021","journal-title":"Nat. Aging."},{"key":"10.1016\/j.aca.2023.341356_bib9","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/s41421-020-0141-7","article-title":"Lysosome biology in autophagy","volume":"6","author":"Yim","year":"2020","journal-title":"Cell. Discov."},{"key":"10.1016\/j.aca.2023.341356_bib10","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/s41556-018-0176-2","article-title":"Mechanisms of mitophagy in cellular homeostasis, physiology and pathology","volume":"20","author":"Palikaras","year":"2018","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.aca.2023.341356_bib11","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cell.2007.12.018","article-title":"Autophagy in the pathogenesis of disease","volume":"132","author":"Levine","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.aca.2023.341356_bib12","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1080\/15548627.2016.1212787","article-title":"Lysosome calcium in ROS regulation of autophagy","volume":"12","author":"Zhang","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.aca.2023.341356_bib13","doi-asserted-by":"crossref","first-page":"12234","DOI":"10.1039\/C4CC03312D","article-title":"Fluorescent probes for hydrogen sulfide detection and bioimaging","volume":"50","author":"Yu","year":"2014","journal-title":"Chem. Commun."},{"key":"10.1016\/j.aca.2023.341356_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2020.116117","article-title":"Small-molecule fluorescent probes for H2S detection: advances and perspectives","volume":"134","author":"Li","year":"2021","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.aca.2023.341356_bib15","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.abb.2011.09.015","article-title":"The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology","volume":"516","author":"Francoleon","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.aca.2023.341356_bib16","doi-asserted-by":"crossref","first-page":"16673","DOI":"10.1021\/acs.analchem.1c04246","article-title":"Highly selective fluorescent probe design for visualizing hepatic hydrogen sulfide in the pathological progression of nonalcoholic fatty liver","volume":"93","author":"Li","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.341356_bib17","doi-asserted-by":"crossref","first-page":"7800","DOI":"10.1021\/ic500664c","article-title":"Chemically reversible reactions of hydrogen sulfide with metal phthalocyanines","volume":"53","author":"Hartle","year":"2014","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.aca.2023.341356_bib18","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","article-title":"Hydrogen sulfide and cell signaling","volume":"51","author":"Li","year":"2011","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.aca.2023.341356_bib19","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nrm3391","article-title":"H\u2082S signalling through protein sulfhydration and beyond","volume":"13","author":"Bindu","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.aca.2023.341356_bib20","doi-asserted-by":"crossref","first-page":"10529","DOI":"10.1039\/c2cc34031c","article-title":"A near-infrared fluorescent turn-on probe for fluorescence imaging of hydrogen sulfide in living cells based on thiolysis of dinitrophenyl ether","volume":"48","author":"Cao","year":"2012","journal-title":"Chem. Commun."},{"key":"10.1016\/j.aca.2023.341356_bib21","doi-asserted-by":"crossref","first-page":"5700","DOI":"10.1021\/acs.analchem.0c04639","article-title":"Near-infrared mitochondria-targetable fluorescent probe for high-contrast bioimaging of H2S","volume":"93","author":"Gong","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2023.341356_bib22","first-page":"2310","article-title":"A lysosome-targetable fluorescent probe for imaging hydrogen sulfide in living cells, org","volume":"9","author":"Liu","year":"2013","journal-title":"Lettres"},{"key":"10.1016\/j.aca.2023.341356_bib23","doi-asserted-by":"crossref","first-page":"7492","DOI":"10.1002\/anie.201500088","article-title":"Self-immolative spacers: kinetic aspects, structure-property relationships, and applications","volume":"54","author":"Alouane","year":"2015","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.aca.2023.341356_bib24","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.1021\/cr900249z","article-title":"Fluorescent indicators for intracellular pH","volume":"110","author":"Han","year":"2010","journal-title":"Chem. Rev."},{"key":"10.1016\/j.aca.2023.341356_bib25","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.yexcr.2012.03.005","article-title":"Lysosomal pathways to cell death and their therapeutic applications","volume":"318","author":"\u010cesen","year":"2012","journal-title":"Cell Res."},{"key":"10.1016\/j.aca.2023.341356_bib26","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1089\/ars.2014.5869","article-title":"Signaling molecules: hydrogen sulfide and polysulfide","volume":"22","author":"Kimura","year":"2015","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.aca.2023.341356_bib27","doi-asserted-by":"crossref","first-page":"16633","DOI":"10.1073\/pnas.0902952106","article-title":"No facilitator required for membrane transport of hydrogen sulfide","volume":"106","author":"Mathai","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.aca.2023.341356_bib28","doi-asserted-by":"crossref","first-page":"6019","DOI":"10.1021\/ma800621h","article-title":"Mixed mode Thiol\u2212Acrylate photopolymerizations for the synthesis of PEG\u2212Peptide hydrogels","volume":"41","author":"Salinas","year":"2008","journal-title":"Macromolecules"},{"key":"10.1016\/j.aca.2023.341356_bib29","doi-asserted-by":"crossref","first-page":"10529","DOI":"10.1039\/c2cc34031c","article-title":"A near-infrared fluorescent turn-on probe for fluorescence imaging of hydrogen sulfide in living cells based on thiolysis of dinitrophenyl ether","volume":"48","author":"Cao","year":"2012","journal-title":"Chem. Commun."},{"key":"10.1016\/j.aca.2023.341356_bib30","doi-asserted-by":"crossref","first-page":"17973","DOI":"10.1021\/jacs.9b09181","article-title":"An optical\/photoacoustic dual-modality probe: ratiometric in\/ex vivo imaging for stimulated H2S upregulation in mice","volume":"141","author":"Chen","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2023.341356_bib31","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1089\/ars.2014.5933","article-title":"The therapeutic potential of cystathionine beta-synthetase\/hydrogen sulfide inhibition in cancer","volume":"22","author":"Hellmich","year":"2015","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.aca.2023.341356_bib32","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nrd.2015.1","article-title":"Gasotransmitters in cancer: from pathophysiology to experimental therapy","volume":"15","author":"Szabo","year":"2016","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.aca.2023.341356_bib33","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jphs.2019.05.007","article-title":"Rapamycin activates mammalian microautophagy","volume":"140","author":"Masahiro","year":"2019","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.aca.2023.341356_bib34","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1089\/ars.2008.2073","article-title":"H2S protects against methionine-induced oxidative stress in brain endothelial cells","volume":"11","author":"Tyagi","year":"2009","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.aca.2023.341356_bib35","doi-asserted-by":"crossref","first-page":"154","DOI":"10.4161\/auto.3634","article-title":"Autophagosome-lysosome fusion depends on the pH in acidic compartments in CHO cells","volume":"3","author":"Akinori","year":"2007","journal-title":"Autophagy"},{"key":"10.1016\/j.aca.2023.341356_bib36","doi-asserted-by":"crossref","first-page":"7508","DOI":"10.1021\/ac501263d","article-title":"Design of a simultaneous target and location-activatable fluorescent probe for visualizing hydrogen sulfide in lysosomes","volume":"86","author":"Yang","year":"2014","journal-title":"Anal. Chem."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023005779?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023005779?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:43:15Z","timestamp":1762083795000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267023005779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":36,"alternative-id":["S0003267023005779"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2023.341356","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monitoring H2S fluctuation during autophagic fusion of lysosomes and mitochondria using a lysosome-targeting fluorogenic probe","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2023.341356","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"341356"}}