{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:59:36Z","timestamp":1793163576407,"version":"4.5.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31801645"],"award-info":[{"award-number":["31801645"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003787","name":"Natural Science Foundation of Hebei Province","doi-asserted-by":"publisher","award":["C2020204130"],"award-info":[{"award-number":["C2020204130"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.aca.2023.341609","type":"journal-article","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T14:42:26Z","timestamp":1689000146000},"page":"341609","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Evolution of a natural TetR protein and development of a Fe3O4 assisted semi-homogeneous fluorescent method for determination of tetracyclines in milk"],"prefix":"10.1016","volume":"1276","author":[{"given":"Wan Qiu","family":"Xia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2112-0218","authenticated-orcid":false,"given":"Jian Ping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2023.341609_bib1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.trac.2016.12.010","article-title":"Immunochemical techniques for multianalyte analysis of chemical residues in food and the environment: a review","volume":"88","author":"Li","year":"2017","journal-title":"TRAC-Trend Anal. Chem."},{"key":"10.1016\/j.aca.2023.341609_bib2","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.talanta.2017.01.057","article-title":"Receptor-based screening assays for the detection of antibiotics residues-A review","volume":"166","author":"Ahmeda","year":"2017","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2023.341609_bib3","doi-asserted-by":"crossref","first-page":"13953","DOI":"10.1021\/acs.jafc.1c05674","article-title":"Development of a dihydropteroate synthase based fluorescence polarization assay for detection of sulfonamides and studying its recognition mechanism","volume":"69","author":"He","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2023.341609_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/bios8010001","article-title":"Label-free biosensor detection of endocrine disrupting compounds using engineered estrogen receptors","volume":"8","author":"Spina","year":"2018","journal-title":"Biosensors"},{"key":"10.1016\/j.aca.2023.341609_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2019.104354","article-title":"Development and validation of an enzyme-linked receptor assay based on mutant protein I188K\/S19C\/G24C for 40 beta-lactams antibiotics detection in 13 food samples","volume":"152","author":"Ahmed","year":"2020","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2023.341609_bib6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.aca.2007.02.057","article-title":"Solubilisation and binding characteristics of a recombinant beta2-adrenergic receptor expressed in the membrane of Escherichia coli for the multianalyte detection of beta-agonists and antagonists residues in food-producing animals","volume":"589","author":"Danyi","year":"2007","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2023.341609_bib7","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.3390\/foods11203196","article-title":"Development of a fluorescence polarization assay for multi-determination of 10 aminoglycosides in pork muscle sample based on ribosomal protein S12 and studying its recognition mechanism","volume":"11","author":"Xia","year":"2022","journal-title":"Foods"},{"key":"10.1016\/j.aca.2023.341609_bib8","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ab.2018.10.017","article-title":"A receptor-based chemiluminescence enzyme linked immunosorbent assay for determination of tetracyclines in milk","volume":"564\/565","author":"Wang","year":"2019","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.aca.2023.341609_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2019.104184","article-title":"Directional evolution of TetR protein and development of a fluoroimmunoassay for screening of tetracyclines in egg","volume":"150","author":"Wang","year":"2019","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2023.341609_bib10","doi-asserted-by":"crossref","first-page":"3850","DOI":"10.3390\/foods11233850","article-title":"Identification and evolution of a natural Tetr protein based on molecular docking and development of a fluorescence polarization assay for multi-detection of 10 tetracyclines in milk","volume":"11","author":"Xia","year":"2022","journal-title":"Foods"},{"key":"10.1016\/j.aca.2023.341609_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.340481","article-title":"Evolution of a natural dihydropteroate synthase and development of a signal amplified fluorescence method for detection of 44 sulfonamides in milk","volume":"1234","author":"He","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2023.341609_bib12","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.snb.2019.04.139","article-title":"Enhanced competitive immunomagnetic beads assay with gold nanoparticles and carbon nanotube-assisted multiple enzyme probes","volume":"292","author":"Zeng","year":"2019","journal-title":"Sensor. Actuator. B."},{"key":"10.1016\/j.aca.2023.341609_bib13","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1007\/s00217-021-03777-z","article-title":"A sensitive chemiluminescence immunoassay based on immunomagnetic beads for quantitative detection of zearalenone","volume":"247","author":"Zhang","year":"2021","journal-title":"Eur. Food Res. Technol."},{"key":"10.1016\/j.aca.2023.341609_bib14","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1093\/jaoacint\/qsab104","article-title":"Establishment of a chemiluminescence immunoassay combined with immunomagnetic beads for rapid analysis of ochratoxin A","volume":"105","author":"Zhang","year":"2022","journal-title":"J. AOAC Int."},{"key":"10.1016\/j.aca.2023.341609_bib15","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1146\/annurev-biochem-061516-044839","article-title":"Teaching old dyes new tricks: biological probes built from fluoresceins and rhodamines","volume":"86","author":"Lavis","year":"2017","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.aca.2023.341609_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2010.05.026","article-title":"Beyond labels: a review of the application of quantum dots as integrated components of assays, bioprobes, and biosensors utilizing optical transduction","volume":"673","author":"Russ Algar","year":"2010","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2023.341609_bib17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.aca.2007.05.045","article-title":"Synthesis of haptens and development of a sensitive immunoassay for tetracycline residues: application to honey samples","volume":"594","author":"Pastor-Navarro","year":"2007","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2023.341609_bib18","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.aca.2008.08.003","article-title":"Quantitative detection of tetracycline residues in honey by a simple sensitive immunoassay","volume":"626","author":"Jeon","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2023.341609_bib19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1021\/jf062627s","article-title":"Preparation of antitetracycline antibodies and development of an indirect heterologous competitive enzyme-linked immunosorbent assay to detect residues of tetracycline in milk","volume":"55","author":"Zhang","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2023.341609_bib20","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1080\/09540100802117875","article-title":"Preparation and validation of the polyclonal antibodies for detection of chlortetracycline residues","volume":"19","author":"Zhao","year":"2008","journal-title":"Food Agric. Immunol."},{"key":"10.1016\/j.aca.2023.341609_bib21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/09540100903078604","article-title":"Improved group determination of tetracycline antibiotics in competitive enzyme linked immunosorbent assay","volume":"20","author":"Burkin","year":"2009","journal-title":"Food Agric. Immunol."},{"key":"10.1016\/j.aca.2023.341609_bib22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/09540100902849740","article-title":"Development of an indirect competitive ELISA for the detection of doxycycline residue in animal edible tissues","volume":"20","author":"Le","year":"2009","journal-title":"Food Agric. Immunol."},{"key":"10.1016\/j.aca.2023.341609_bib23","doi-asserted-by":"crossref","first-page":"3837","DOI":"10.1021\/jf2053355","article-title":"Preparation of antibodies and development of an enzyme-linked immunosorbent assay (ELISA) for the determination of doxycycline antibiotic in milk samples","volume":"60","author":"Adrian","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2023.341609_bib24","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1080\/03601234.2013.726856","article-title":"Production of monoclonal antibody against doxycycline for immunoassay of seven tetracyclines in bovine muscle and milk","volume":"48","author":"Gao","year":"2013","journal-title":"J. Environ. Sci. Health B."},{"key":"10.1016\/j.aca.2023.341609_bib25","first-page":"145","article-title":"Detection of oxytetracycline residues in honey samples using ELISA and HPLC methods","volume":"19","author":"Mahmoudi","year":"2014","journal-title":"J. Pharmaceut. Sci."},{"key":"10.1016\/j.aca.2023.341609_bib26","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1080\/09540105.2015.1036357","article-title":"Screening, determination and confirmation of tetracycline residues in chicken tissues using four-plate test, ELISA and HPLC-UV methods: comparison between correlation results","volume":"26","author":"Shahbazi","year":"2015","journal-title":"Food Agric. Immunol."},{"key":"10.1016\/j.aca.2023.341609_bib27","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1080\/09540105.2015.1036355","article-title":"A competitive dual-label time-resolved fluoroimmunoassay for the simultaneous detection of chlortetracycline and doxycycline in animal edible tissues","volume":"26","author":"Le","year":"2015","journal-title":"Food Agric. Immunol."},{"key":"10.1016\/j.aca.2023.341609_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/bit.20224","article-title":"Broad-spectrum protein biosensors for class-specific detection of antibiotics","volume":"89","author":"Weber","year":"2005","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.aca.2023.341609_bib29","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.jbiotec.2006.11.011","article-title":"A novel generic dipstick-based technology for rapid and precise detection of tetracycline, streptogramin and macrolide antibiotics in food samples","volume":"128","author":"Link","year":"2007","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.aca.2023.341609_bib30","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1007\/s00216-019-02368-y","article-title":"Flow-based regenerable chemiluminescence receptor assay for the detection of tetracyclines","volume":"412","author":"Meyer","year":"2020","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.aca.2023.341609_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2021.106779","article-title":"Synthesis of photoaffinity labeled activity-based protein profiling probe and production of natural TetR protein for immunoassay of tetracyclines in milk","volume":"170","author":"Xia","year":"2021","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2023.341609_bib32","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s12161-020-01744-0","article-title":"Determination of tetracyclines in chicken by dispersive solid phase microextraction based on metal-organic frameworks\/molecularly imprinted nano-polymer and ultra performance liquid chromatography","volume":"13","author":"Ma","year":"2020","journal-title":"Food Anal. Methods"},{"key":"10.1016\/j.aca.2023.341609_bib33","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1021\/acs.jafc.6b05337","article-title":"A dual-color quantum dots encoded frit-based immunoassay for visual detection of aflatoxin M1 and pirlimycin residues in milk","volume":"65","author":"Jiang","year":"2017","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2023.341609_bib34","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.foodchem.2015.11.116","article-title":"Dual-label quantum dot-based immunoassay for simultaneous determination of carbadox and olaquindox metabolites in animal tissues","volume":"199","author":"Le","year":"2016","journal-title":"Food Chem."},{"key":"10.1016\/j.aca.2023.341609_bib35","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1007\/s12161-018-1198-x","article-title":"One-step core\/multishell quantum dots-based fluoroimmunoassay for screening of deoxynivalenol in maize","volume":"11","author":"Zhang","year":"2018","journal-title":"Food Anal. Methods"},{"key":"10.1016\/j.aca.2023.341609_bib36","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1007\/s00216-019-01643-2","article-title":"Quantitative and rapid detection of amantadine and chloramphenicol based on various quantum dots with the same excitations","volume":"411","author":"Xie","year":"2019","journal-title":"Anal. Bioanal. Chem."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023008309?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267023008309?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T20:02:47Z","timestamp":1757707367000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267023008309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":36,"alternative-id":["S0003267023008309"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2023.341609","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evolution of a natural TetR protein and development of a Fe3O4 assisted semi-homogeneous fluorescent method for determination of tetracyclines in milk","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2023.341609","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"341609"}}