{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:26:08Z","timestamp":1786983968203,"version":"build-2736575974"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21904078"],"award-info":[{"award-number":["21904078"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21976209"],"award-info":[{"award-number":["21976209"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22376216"],"award-info":[{"award-number":["22376216"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.aca.2024.342440","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T08:32:00Z","timestamp":1709195520000},"page":"342440","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Colorimetric and fluorescent independent dual \u201csignal on\u201d biosensor for accurate detection of ochratoxin A based on aptamer-triggered biocatalytic reactions"],"prefix":"10.1016","volume":"1299","author":[{"given":"Hao","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingdi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaokun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingxin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2024.342440_bib1","doi-asserted-by":"crossref","first-page":"632","DOI":"10.3390\/ijerph14060632","article-title":"Occurrence, toxicity, and analysis of major mycotoxins in food","volume":"14","author":"Alshannaq","year":"2017","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.aca.2024.342440_bib2","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-2885.2006.00718.x","article-title":"Immunotoxic activity of ochratoxin A","volume":"29","author":"Al\u2010Anati","year":"2006","journal-title":"J. Vet. Pharmacol. Therapeut."},{"key":"10.1016\/j.aca.2024.342440_bib3","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.toxicon.2020.08.031","article-title":"Ochratoxins in food and feed: occurrence and its impact on human health and management strategies","volume":"187","author":"Kumar","year":"2020","journal-title":"Toxicon"},{"key":"10.1016\/j.aca.2024.342440_bib4","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.fct.2018.01.002","article-title":"Toxicity, oxidative stress and metabolism","volume":"112","author":"Tao","year":"2018","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.aca.2024.342440_bib5","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1021\/tx700027j","article-title":"Ochratoxin A-induced mutagenesis in mammalian cells is consistent with the production of oxidative stress","volume":"20","author":"Palma","year":"2007","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.aca.2024.342440_bib6","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1021\/jf0100651","article-title":"Assay of ochratoxin A in wine and beer by high-pressure liquid chromatography photodiode array and gas chromatography mass selective detection","volume":"49","author":"Soleas","year":"2001","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2024.342440_bib7","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1021\/jf960442n","article-title":"Sensitive ELISA test for determination of ochratoxin A","volume":"44","author":"Barna-Vetr\u00f3","year":"1996","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2024.342440_bib8","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.fct.2013.09.010","article-title":"A comparison of ELISA and HPLC methods for determination of ochratoxin A in human blood serum in the Czech Republic","volume":"62","author":"Dohnal","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.aca.2024.342440_bib9","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.biotechadv.2015.02.008","article-title":"Current approaches in SELEX: an update to aptamer selection technology","volume":"33","author":"Darmostuk","year":"2015","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.aca.2024.342440_bib10","doi-asserted-by":"crossref","first-page":"10068","DOI":"10.1021\/acs.analchem.3c01485","article-title":"CRISPR\/Cas12a-mediated aptasensor based on tris-(8-hydroxyquinoline) aluminum microcrystals with crystallization-induced enhanced electrochemiluminescence for acetamiprid analysis","volume":"95","author":"Peng","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2024.342440_bib11","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1021\/acsnano.7b00373","article-title":"Aptasensor with expanded nucleotide using DNA nanotetrahedra for electrochemical detection of cancerous exosomes","volume":"11","author":"Wang","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.aca.2024.342440_bib12","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1021\/acs.analchem.0c04308","article-title":"Precise capture and direct quantification of tumor exosomes via a highly efficient dual-aptamer recognition-assisted ratiometric immobilization-free electrochemical strategy","volume":"93","author":"Yang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2024.342440_bib13","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1021\/acs.analchem.6b05109","article-title":"Ultrasensitive self-powered aptasensor based on enzyme biofuel cell and DNA bioconjugate: a facile and powerful tool for antibiotic residue detection","volume":"89","author":"Gai","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2024.342440_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115346","article-title":"Metal-mediated Fe3O4@polydopamine-aptamer capture nanoprobe coupling multifunctional MXene@Au@Pt nanozyme for direct and portable photothermal analysis of circulating breast cancer cells","volume":"234","author":"Yang","year":"2023","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2024.342440_bib15","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1021\/acs.jafc.1c06476","article-title":"Aptamer\u2013target recognition-promoted ratiometric electrochemical strategy for evaluating the Microcystin-LR residue in fish without interferences","volume":"70","author":"Li","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2024.342440_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131995","article-title":"A colorimetric aptasensor fabricated with group-specific split aptamers and complex nanozyme for enrofloxacin and ciprofloxacin determination","volume":"458","author":"Wang","year":"2023","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.aca.2024.342440_bib17","doi-asserted-by":"crossref","first-page":"16000","DOI":"10.1021\/acsomega.2c08040","article-title":"Colorimetric aptasensor for the visual and microplate determination of clusterin in human urine based on aggregation characteristics of gold nanoparticles","volume":"8","author":"Wen","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.aca.2024.342440_bib18","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.snb.2016.03.140","article-title":"Fluorescence analyzer based on smartphone camera and wireless for detection of Ochratoxin A","volume":"232","author":"Bueno","year":"2016","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2024.342440_bib19","doi-asserted-by":"crossref","first-page":"8493","DOI":"10.1021\/acs.analchem.1c00796","article-title":"A Fluorescence assay for exosome detection based on bivalent cholesterol anchor triggered target conversion and enzyme-free signal amplification","volume":"93","author":"Wang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2024.342440_bib20","doi-asserted-by":"crossref","first-page":"9021","DOI":"10.1021\/acsnano.0c04031","article-title":"DNA tetrahedra modules as versatile optical sensing platforms for multiplexed analysis of miRNAs, endonucleases, and aptamer\u2013ligand complexes","volume":"14","author":"Zhou","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.aca.2024.342440_bib21","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1021\/acssensors.1c00596","article-title":"Sensitive detection of SARS-CoV-2 using a SERS-based aptasensor","volume":"6","author":"Chen","year":"2021","journal-title":"ACS Sens."},{"key":"10.1016\/j.aca.2024.342440_bib22","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1021\/acssensors.0c01162","article-title":"AuNanostar@4-MBA@Au core-shell nanostructure coupled with exonuclease III-assisted cycling amplification for ultrasensitive SERS detection of ochratoxin A","volume":"5","author":"Huang","year":"2020","journal-title":"ACS Sens."},{"key":"10.1016\/j.aca.2024.342440_bib23","doi-asserted-by":"crossref","first-page":"8063","DOI":"10.1021\/acs.analchem.3c01033","article-title":"Fluorescence and colorimetric analysis of african swine fever virus based on the RPA-assisted CRISPR\/Cas12a strategy","volume":"95","author":"Mao","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2024.342440_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.129288","article-title":"Dual-mode detection of PARP-1 by fluorescence and chemiluminescence","volume":"330","author":"Xu","year":"2021","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2024.342440_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2023.133693","article-title":"Fluorescent nanoswitch based on redox-controlled reversible sulfhydryl functionalized carbon dots for highly sensitive detection of ochratoxin A","volume":"385","author":"Zhan","year":"2023","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2024.342440_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.124603","article-title":"A label-free colorimetric 3D paper-based device for ochratoxin A detection using G-quadruplex\/hemin DNAzyme with a smartphone readout","volume":"260","author":"Zhang","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2024.342440_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126962","article-title":"Engineering DNA G-quadruplex assembly for label-free detection of Ochratoxin A in colorimetric and fluorescent dual modes","volume":"423","author":"He","year":"2022","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.aca.2024.342440_bib28","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1039\/D1AN02335G","article-title":"A sensitive and simple competitive nanozyme-linked apta-sorbent assay for the dual-mode detection of ochratoxin A","volume":"147","author":"Li","year":"2022","journal-title":"Analyst"},{"key":"10.1016\/j.aca.2024.342440_bib29","article-title":"Methylmercury-sensitized \u201cturn on\u201d SERS-active peroxidase-like activity of carbon dots\/Au NPs nanozyme for selective detection of ochratoxin A in coffee","volume":"434","author":"Li","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.aca.2024.342440_bib30","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1021\/acs.analchem.1c04537","article-title":"Target-responsive smart nanomaterials via a Au\u2013S binding encapsulation strategy for electrochemical\/colorimetric dual-mode paper-based analytical devices","volume":"94","author":"Zhang","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2024.342440_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113146","article-title":"Electrochemical\/visual dual-readout aptasensor for Ochratoxin A detection integrated into a miniaturized paper-based analytical device","volume":"180","author":"Zhang","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2024.342440_bib32","doi-asserted-by":"crossref","first-page":"5615","DOI":"10.1021\/acsami.1c22809","article-title":"Simple design concept for dual-channel detection of ochratoxin a based on bifunctional metal\u2013organic framework","volume":"14","author":"Li","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.aca.2024.342440_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114164","article-title":"A fluorescence and surface-enhanced Raman scattering dual-mode aptasensor for rapid and sensitive detection of ochratoxin A","volume":"207","author":"Wang","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2024.342440_bib34","doi-asserted-by":"crossref","first-page":"7731","DOI":"10.1021\/jacs.2c00478","article-title":"Structural insights into the mechanism of high-affinity binding of ochratoxin A by a DNA aptamer","volume":"144","author":"Xu","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2024.342440_bib35","doi-asserted-by":"crossref","DOI":"10.1002\/smll.201870179","article-title":"Sensitive and reproducible immunoassay of multiple mycotoxins using surface\u2010enhanced Raman scattering mapping on 3D plasmonic nanopillar arrays","volume":"14","author":"Wang","year":"2018","journal-title":"Small"},{"key":"10.1016\/j.aca.2024.342440_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2021.108661","article-title":"Aptamer-engineered nanomaterials to aid in mycotoxin determination","volume":"135","author":"Xiong","year":"2022","journal-title":"Food Control"},{"key":"10.1016\/j.aca.2024.342440_bib37","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1093\/nar\/gkr504","article-title":"Rational, modular adaptation of enzyme-free DNA circuits to multiple detection methods","volume":"39","author":"Li","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.aca.2024.342440_bib38","doi-asserted-by":"crossref","first-page":"10456","DOI":"10.1021\/jf801957h","article-title":"Determination of ochratoxin A with a DNA aptamer","volume":"56","author":"Cruz-Aguado","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2024.342440_bib39","doi-asserted-by":"crossref","first-page":"5095","DOI":"10.1073\/pnas.1701132114","article-title":"Single-stranded nucleic acid elasticity arises from internal electrostatic tension","volume":"114","author":"Jacobson","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.aca.2024.342440_bib40","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1021\/ac051453v","article-title":"Plastic ELISA-on-a-chip based on sequential cross-flow chromatography","volume":"78","author":"Cho","year":"2006","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2024.342440_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.131609","article-title":"Zeolitic imidazolate frameworks-derived hollow Co\/N-doped CNTs as oxidase-mimic for colorimetric-fluorescence immunoassay of ochratoxin A","volume":"359","author":"Chen","year":"2022","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2024.342440_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121440","article-title":"Fluorescence and absorbance dual-mode immunoassay for detecting Ochratoxin A","volume":"279","author":"Xiao","year":"2022","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267024002411?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267024002411?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T20:11:23Z","timestamp":1757707883000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267024002411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":42,"alternative-id":["S0003267024002411"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2024.342440","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Colorimetric and fluorescent independent dual \u201csignal on\u201d biosensor for accurate detection of ochratoxin A based on aptamer-triggered biocatalytic reactions","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2024.342440","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"342440"}}