{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:24:35Z","timestamp":1786983875597,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81527801"],"award-info":[{"award-number":["81527801"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001644"],"award-info":[{"award-number":["82001644"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61904057"],"award-info":[{"award-number":["61904057"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007046","name":"Wuhan University","doi-asserted-by":"publisher","award":["2021127"],"award-info":[{"award-number":["2021127"]}],"id":[{"id":"10.13039\/501100007046","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.aca.2025.343690","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T18:52:21Z","timestamp":1737399141000},"page":"343690","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Detecting monogenic disorders in utero non-invasively based on fetal nucleated red blood cells highly-purified by multi-functional magnetic nanoparticles"],"prefix":"10.1016","volume":"1343","author":[{"given":"Lin","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naiqi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqi","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saisai","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0836-6974","authenticated-orcid":false,"given":"Bo","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingzhong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanzhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2025.343690_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/pd.5208","volume":"38","author":"Chitty","year":"2018","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.aca.2025.343690_bib3","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1001\/jama.2014.14601","volume":"312","author":"Yang","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.aca.2025.343690_bib4","first-page":"28","volume":"4","author":"Prior-de Castro","year":"2023","journal-title":"Adv. Lab. Med."},{"key":"10.1016\/j.aca.2025.343690_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1373\/clinchem.2019.304238","volume":"66","author":"Scotchman","year":"2020","journal-title":"Clin. Chem."},{"key":"10.1016\/j.aca.2025.343690_bib6","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1007\/s00439-019-02061-1","volume":"139","author":"Guseh","year":"2020","journal-title":"Hum. Genet."},{"key":"10.1016\/j.aca.2025.343690_bib7","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jgg.2023.08.001","volume":"51","author":"Zhang","year":"2024","journal-title":"J. Genet. Genomics"},{"key":"10.1016\/j.aca.2025.343690_bib8","series-title":"Pharmaceutics","author":"Clarke","year":"2023"},{"key":"10.1016\/j.aca.2025.343690_bib9","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.clp.2022.06.005","volume":"49","author":"Berkowitz","year":"2022","journal-title":"Clin. Perinatol."},{"key":"10.1016\/j.aca.2025.343690_bib10","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1111\/1471-0528.16821","volume":"129","author":"Navaratnam","year":"2022","journal-title":"BJOG An Int. J. Obstet. Gynaecol."},{"key":"10.1016\/j.aca.2025.343690_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2024.1388481","volume":"11","author":"Eltabbakh","year":"2024","journal-title":"Front. Med."},{"key":"10.1016\/j.aca.2025.343690_bib12","series-title":"Diagnostics","author":"Sabbatinelli","year":"2021"},{"key":"10.1016\/j.aca.2025.343690_bib13","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1016\/j.csbj.2020.09.003","volume":"18","author":"Rabinowitz","year":"2020","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.aca.2025.343690_bib14","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.ejogrb.2020.08.001","volume":"253","author":"Scotchman","year":"2020","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.aca.2025.343690_bib15","first-page":"94","volume":"vol. 23","author":"Hayward","year":"2018"},{"key":"10.1016\/j.aca.2025.343690_bib16","series-title":"Journal of Personalized Medicine","author":"Gullo","year":"2023"},{"key":"10.1016\/j.aca.2025.343690_bib17","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1042\/CS20210380","volume":"136","author":"Hanson","year":"2022","journal-title":"Clin. Sci."},{"key":"10.1016\/j.aca.2025.343690_bib18","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev-genom-110821-113411","volume":"23","author":"Zhong","year":"2022","journal-title":"Annu. Rev. Genom. Hum. Genet."},{"key":"10.1016\/j.aca.2025.343690_bib19","volume":"vol. 788","author":"Rosner","year":"2021"},{"key":"10.1016\/j.aca.2025.343690_bib20","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1515\/cclm-2012-0601","volume":"51","author":"Chiu","year":"2013","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.aca.2025.343690_bib21","series-title":"International Journal of Molecular Sciences","author":"Jou","year":"2023"},{"key":"10.1016\/j.aca.2025.343690_bib22","doi-asserted-by":"crossref","first-page":"4119","DOI":"10.1360\/TB-2023-0348","volume":"68","author":"Wu","year":"2023","journal-title":"Chin. Sci. Bull.-Chin."},{"key":"10.1016\/j.aca.2025.343690_bib23","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1186\/s12951-022-01749-3","volume":"20","author":"Chen","year":"2022","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.aca.2025.343690_bib24","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1021\/acsabm.0c01325","volume":"4","author":"Wei","year":"2021","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.aca.2025.343690_bib25","volume":"32","author":"Dong","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.aca.2025.343690_bib26","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1021\/acs.analchem.0c03933","volume":"93","author":"Wang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2025.343690_bib27","volume":"28","author":"Rao","year":"2018","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.aca.2025.343690_bib28","doi-asserted-by":"crossref","first-page":"28732","DOI":"10.1021\/acsami.9b10318","volume":"11","author":"Meng","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.aca.2025.343690_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114425","volume":"213","author":"Wu","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2025.343690_bib30","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/nature10606","volume":"480","author":"Crosnier","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.aca.2025.343690_bib31","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/pd.1970130408","volume":"13","author":"Bianchi","year":"1993","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.aca.2025.343690_bib32","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1093\/clinchem\/45.9.1614","volume":"45","author":"Alvarez","year":"1999","journal-title":"Clin. Chem."},{"key":"10.1016\/j.aca.2025.343690_bib33","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/S0140-6736(73)91675-9","volume":"301","author":"Pembrey","year":"1973","journal-title":"Lancet"},{"key":"10.1016\/j.aca.2025.343690_bib34","first-page":"6188","volume":"vol. 81","author":"Chung","year":"1984"},{"key":"10.1016\/j.aca.2025.343690_bib35","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/s41576-024-00692-3","volume":"25","author":"Tanudisastro","year":"2024","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.aca.2025.343690_bib36","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/uog.12331","volume":"41","author":"Ashoor","year":"2013","journal-title":"Ultrasound Obstet. Gynecol."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267025000844?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267025000844?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:48:26Z","timestamp":1762084106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267025000844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":35,"alternative-id":["S0003267025000844"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2025.343690","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detecting monogenic disorders in utero non-invasively based on fetal nucleated red blood cells highly-purified by multi-functional magnetic nanoparticles","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2025.343690","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"343690"}}