{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T22:34:36Z","timestamp":1793918076167,"version":"4.8.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013254","name":"National College Students Innovation and Entrepreneurship Training Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013254","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014980","name":"Wannan Medical College","doi-asserted-by":"publisher","award":["S202410368090"],"award-info":[{"award-number":["S202410368090"]}],"id":[{"id":"10.13039\/501100014980","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.aca.2025.344778","type":"journal-article","created":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T14:19:14Z","timestamp":1760278754000},"page":"344778","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["TICT-activated viscosity sensitive mitochondrial probes for imaging and early diagnosis of drug-induced liver injury"],"prefix":"10.1016","volume":"1380","author":[{"given":"Jie","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifeiyang","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiyuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunjia","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5253-1204","authenticated-orcid":false,"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2025.344778_bib1","doi-asserted-by":"crossref","first-page":"6949","DOI":"10.1007\/s11033-021-06674-6","article-title":"Mitochondrial stress response in drug-induced liver injury","volume":"48","author":"Zheng","year":"2021","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.aca.2025.344778_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202402656","article-title":"Redox-responsive AIEgen diselenide-covalent organic framework composites targeting hepatic macrophages for treatment of drug-induced liver injury","volume":"20","author":"Zhuang","year":"2024","journal-title":"Small"},{"key":"10.1016\/j.aca.2025.344778_bib3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s00018-025-05744-3","article-title":"Mechanisms of drug induced liver injury","volume":"82","author":"Skat-R\u00f8rdam","year":"2025","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.aca.2025.344778_bib4","doi-asserted-by":"crossref","DOI":"10.1111\/liv.70019","article-title":"Drug\u2010induced liver injury in patients with chronic liver disease","volume":"45","author":"Ghabril","year":"2025","journal-title":"Liver Int."},{"key":"10.1016\/j.aca.2025.344778_bib5","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1021\/acs.analchem.4c06168","article-title":"Super-resolution mitochondrial fluorescent probe for accurate monitoring of drug-induced liver injury","volume":"97","author":"Zheng","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib6","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.3390\/ijms24021074","article-title":"Glycogen-endoplasmic reticulum connection in the liver","volume":"24","author":"Mandl","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.aca.2025.344778_bib7","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1093\/toxsci\/kfac082","article-title":"Metabolic competency of larval zebrafish in drug-induced liver injury: a case study of acetaminophen poisoning","volume":"189","author":"Chen","year":"2022","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.aca.2025.344778_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2025.117376","article-title":"Ferritinophagy-derived iron causes protein nitration and mitochondrial dysfunction in acetaminophen-induced liver injury","volume":"500","author":"Liang","year":"2025","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.aca.2025.344778_bib9","article-title":"SMND-309 activates Nrf2 signaling to alleviate acetaminophen-induced hepatotoxicity and oxidative stress","volume":"20","author":"Dong","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/j.aca.2025.344778_bib10","doi-asserted-by":"crossref","DOI":"10.1111\/liv.16167","article-title":"Novel emerging mechanisms in acetaminophen (APAP) hepatotoxicity","volume":"45","author":"Hionides-Gutierrez","year":"2025","journal-title":"Liver Int."},{"key":"10.1016\/j.aca.2025.344778_bib11","doi-asserted-by":"crossref","first-page":"7784","DOI":"10.1021\/cbmi.4c00056","article-title":"Smart persistent luminescence imaging for early diagnosis of drug-induced liver injury","volume":"3","author":"Zhang","year":"2025","journal-title":"Chem. Biomed. Imaging"},{"key":"10.1016\/j.aca.2025.344778_bib12","doi-asserted-by":"crossref","first-page":"9808","DOI":"10.1021\/acs.analchem.3c05629","article-title":"Lighting up nucleolus to report mitochondria damage using a mitochondria-to-nucleolus migration probe","volume":"96","author":"Wang","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1012872","article-title":"Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation","volume":"21","author":"Sun","year":"2025","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.aca.2025.344778_bib14","doi-asserted-by":"crossref","first-page":"10635","DOI":"10.1039\/D4TB01486C","article-title":"A novel high signal-to-noise ratio fluorescent probe for real-time mitochondrial viscosity detection and imaging in vitro and in vivo","volume":"12","author":"Fu","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.aca.2025.344778_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2025.343748","article-title":"Visualization of mitochondrial molecular dynamics during mitophagy process by label-free surface-enhanced Raman scattering spectroscopy","volume":"1345","author":"Jia","year":"2025","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2025.344778_bib16","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2403000121","article-title":"Quantifying electron transport in aggregated colloidal suspensions in the strong flow regime","volume":"121","author":"Hipp","year":"2024","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.aca.2025.344778_bib17","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1021\/acs.analchem.2c02235","article-title":"Simultaneous monitoring of HOCl and viscosity with drug-induced pyroptosis in live cells and acute lung injury","volume":"94","author":"Zhan","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.137581","article-title":"A high signal-to-noise ratio NIR fluorescent probe for viscosity detection in NAFLD diagnosis","volume":"433","author":"Hao","year":"2025","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2025.344778_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.343425","article-title":"An AIE-TICT fluorescence probe cascade responsive to H2S, polarity and viscosity to track microenvironment changes in cellular model of ischemia-reperfusion injury","volume":"1334","author":"Ji","year":"2025","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2025.344778_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2024.112102","article-title":"\u201cThree-key-and-lock\u201d near-infrared fluorescent probe for dual-channel tracking ONOO\u2212 in mitochondria and viscosity in lysosomes in ferroptosis and drug-induced liver injury","volume":"225","author":"Liu","year":"2024","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.aca.2025.344778_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2024.215864","article-title":"Recent progress in small molecule fluorescent probes for imaging and diagnosis of non-alcoholic fatty liver disease","volume":"513","author":"Zhou","year":"2024","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.aca.2025.344778_bib22","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.saa.2019.02.068","article-title":"Rational design of NIR fluorescence probes for sensitive detection of viscosity in living cells","volume":"214","author":"Zhang","year":"2019","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2025.344778_bib23","doi-asserted-by":"crossref","first-page":"3677","DOI":"10.1039\/D4TB02711F","article-title":"Mitochondria-targeting fluorescent probe with a pH\/viscosity response for assisted detection of non-alcoholic fatty liver in mice","volume":"13","author":"Wang","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.aca.2025.344778_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2023.215020","article-title":"Coumarin-based near-infrared fluorogenic probes: recent advances, challenges and future perspectives","volume":"480","author":"Fan","year":"2023","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.aca.2025.344778_bib25","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1039\/D5OB00216H","article-title":"pH-Activated NIR fluorescent probe for sensitive mitochondrial viscosity detection","volume":"23","author":"Fu","year":"2025","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib26","doi-asserted-by":"crossref","first-page":"2956","DOI":"10.1039\/D4AN00226A","article-title":"Real-time monitoring of abnormal mitochondrial viscosity in glioblastoma with a novel mitochondria-targeting fluorescent probe","volume":"149","author":"Zhang","year":"2024","journal-title":"Analyst"},{"key":"10.1016\/j.aca.2025.344778_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.137614","article-title":"A triple-targeting and viscosity-sensitive fluorescence probe for visualization of liver injury and tumor models","volume":"434","author":"Lei","year":"2025","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2025.344778_bib28","doi-asserted-by":"crossref","first-page":"3959","DOI":"10.1039\/D4TB02067G","article-title":"Mechanistic study of tumor fluorescence response signals based on a near-infrared viscosity-sensitive probe","volume":"13","author":"Han","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.aca.2025.344778_bib29","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.snb.2017.12.010","article-title":"A novel \u201cturn-on\u201d fluorescent probe with a large stokes shift for homocysteine and cysteine: performance in living cells and zebrafish","volume":"259","author":"Song","year":"2018","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2025.344778_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2021.109825","article-title":"NIR fluorescent probe for dual-response viscosity and hydrogen sulfide and its application in Parkinson's disease model","volume":"197","author":"Li","year":"2022","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.aca.2025.344778_bib31","doi-asserted-by":"crossref","first-page":"15125","DOI":"10.1021\/acs.analchem.3c03437","article-title":"Novel ultralow-potential electrochemiluminescence aptasensor for the highly sensitive detection of zearalenone using a resonance energy transfer system","volume":"95","author":"Xiang","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2022.107192","article-title":"Phenoxazine-conjugated-benzoeindolium as a novel mitochondria-targeted fluorescent probe for turn-on detection of sulfur dioxide and its derivatives in vivo","volume":"175","author":"Zheng","year":"2022","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2025.344778_bib33","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.talanta.2019.05.054","article-title":"Naphthalene-benzoindole derived two novel fluorometric pH-Responsive probes for environmental systems and bioimaging","volume":"203","author":"Cheng","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2025.344778_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136247","article-title":"NQO1 and viscosity tandemly responsive NIR fluorescent probe for tumor imaging and monitoring tumor apoptosis","volume":"418","author":"Cao","year":"2024","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2025.344778_bib35","doi-asserted-by":"crossref","first-page":"10038","DOI":"10.1021\/acs.analchem.5c01131","article-title":"Exploring endoplasmic reticulum dysfunction on protein phase separation using viscosity-sensitive fluorescent lifetime probe click to copy article link","volume":"97","author":"Wei","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.142767","article-title":"In-situ gastritis diagnosis by an oral-administration NIR fluorescent probe with a large stokes shift and high signal-to-noise ratio","volume":"464","author":"Ma","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2025.344778_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116233","article-title":"Multifunctional fluorescence probe for simultaneous detection of viscosity, polarity, and ONOO\u2212 and its bioimaging in vitro and vivo","volume":"254","author":"Li","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2025.344778_bib38","doi-asserted-by":"crossref","first-page":"11455","DOI":"10.1039\/D4TB01767F","article-title":"A membrane-anchored fluorescent probe for the detection of pH in living cells and NAFLD","volume":"12","author":"Yan","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.aca.2025.344778_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2025.112835","article-title":"An indole-fused quinacridone-based fluorescent probe with high photostability and specificity for cellular lipid droplets","volume":"240","author":"Ouyang","year":"2025","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.aca.2025.344778_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.126654","article-title":"Real time precisely tracing the fluctuations of mitochondrial SO2 in cells during ferroptosis and tissues using a mitochondrial-immobilized ratiometric fluorescent probe","volume":"279","author":"Jiang","year":"2024","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2025.344778_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202402537","article-title":"Investigating the therapeutic effects of ferroptosis on myocardial ischemia-reperfusion injury using a dual-locking mitochondrial targeting strategy","volume":"63","author":"Yin","year":"2024","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.aca.2025.344778_bib42","doi-asserted-by":"crossref","first-page":"161","DOI":"10.3390\/metabo14030161","article-title":"Palmitate compromises C6 astrocytic cell viability and mitochondrial function","volume":"14","author":"Schmitt","year":"2024","journal-title":"Metabolites"},{"key":"10.1016\/j.aca.2025.344778_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2019.154835","article-title":"Interplay between oxidative stress and autophagy function and its role in inflammatory cytokine expression induced by palmitate in skeletal muscle cells","volume":"125","author":"Sadeghi","year":"2020","journal-title":"Cytokine"},{"key":"10.1016\/j.aca.2025.344778_bib44","doi-asserted-by":"crossref","first-page":"820","DOI":"10.4149\/neo_2022_211227N1837","article-title":"The oncogenic miR-27a\/BTG2 axis promotes obesity-associated hepatocellular carcinoma by mediating mitochondrial dysfunction","volume":"69","author":"Su","year":"2022","journal-title":"Neoplasma"},{"key":"10.1016\/j.aca.2025.344778_bib45","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.envpol.2018.06.090","article-title":"Cytotoxicity induced by iodinated haloacetamides via ROS accumulation and apoptosis in HepG-2 cells","volume":"242","author":"Hong","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.aca.2025.344778_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2023.122429","article-title":"A long-wavelength mitochondria-targeted fluorescent probe for imaging of peroxynitrite during dexamethasone treatment","volume":"292","author":"Tang","year":"2023","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2025.344778_bib47","doi-asserted-by":"crossref","first-page":"6622","DOI":"10.3390\/ijms25126622","article-title":"The effect of neuronal CoQ10 deficiency and mitochondrial dysfunction on a rotenone-induced neuronal cell model of parkinson's disease","volume":"25","author":"Millichap","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.aca.2025.344778_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2023.123132","article-title":"Hemicyanine-based sensor for mitochondrial viscosity imaging in BV2 cells","volume":"302","author":"Ma","year":"2023","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.aca.2025.344778_bib49","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202304522","article-title":"Mitochondrial-targeted copper delivery for cuproptosis-based synergistic cancer therapy","volume":"13","author":"Deng","year":"2024","journal-title":"Adv. Healthcare Mater."},{"key":"10.1016\/j.aca.2025.344778_bib50","doi-asserted-by":"crossref","first-page":"7279","DOI":"10.1021\/acsomega.2c03992","article-title":"Melatonin mitigates rotenone-induced oxidative stress and mitochondrial dysfunction in the drosophila melanogaster model of parkinson's disease-like symptoms","volume":"8","author":"Rasheed","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.aca.2025.344778_bib51","article-title":"Detecting inflammation in the diabetic mice with a fluorescence lifetime-based probe","volume":"221","author":"Cheng","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2025.344778_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.130862","article-title":"Dual-responsive fluorescent probe for imaging NAD(P)H and mitochondrial viscosity and its application in cancer cell ferroptosis","volume":"350","author":"Wei","year":"2022","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2025.344778_bib53","article-title":"An endoplasmic reticulum-targeting fluorescent probe for the visualization of the viscosity fluctuations during ferroptosis in live cells","volume":"232","author":"Wei","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2025.344778_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.122592","article-title":"A novel water-soluble near-infrared fluorescent probe for monitoring mitochondrial viscosity","volume":"233","author":"Zhang","year":"2021","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2025.344778_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.137104","article-title":"Double-locked probe for NIRF\/PA imaging mitochondrial H2O2 and viscosity in Parkinson's disease","volume":"426","author":"Guo","year":"2025","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.aca.2025.344778_bib56","doi-asserted-by":"crossref","first-page":"3544","DOI":"10.1021\/acs.analchem.2c05713","article-title":"Dihydroxanthene-based near-infrared fluorescent probes for monitoring mitochondrial viscosity in living cells and mice","volume":"95","author":"Wu","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib57","doi-asserted-by":"crossref","first-page":"3709","DOI":"10.1007\/s00216-022-04017-3","article-title":"Metabolite alteration analysis of acetaminophen-induced liver injury using a mass microscope","volume":"414","author":"Matsuyama","year":"2022","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.aca.2025.344778_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2022.106361","article-title":"Progress in the treatment of drug-induced liver injury with natural products","volume":"183","author":"Sun","year":"2022","journal-title":"Pharmacol. Res."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267025011729?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267025011729?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T12:19:21Z","timestamp":1773145161000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267025011729"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":58,"alternative-id":["S0003267025011729"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2025.344778","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TICT-activated viscosity sensitive mitochondrial probes for imaging and early diagnosis of drug-induced liver injury","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2025.344778","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"344778"}}