{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:03:22Z","timestamp":1789736602419,"version":"4.0.1"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100020552","name":"Oman Ministry of Higher Education Research and Innovation","doi-asserted-by":"publisher","award":["BFP\/RGP\/ CBS \/22\/002"],"award-info":[{"award-number":["BFP\/RGP\/ CBS \/22\/002"]}],"id":[{"id":"10.13039\/100020552","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.aca.2026.345205","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:12:01Z","timestamp":1770336721000},"page":"345205","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Exploring lactoferrin as an innovative covalently immobilized chiral selector for the selective separation of pharmaceutical enantiomers using HPLC"],"prefix":"10.1016","volume":"1393","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7421-1220","authenticated-orcid":false,"given":"Adel Ehab","family":"Ibrahim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3359-8145","authenticated-orcid":false,"given":"Samy G.","family":"Alamir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghanem","family":"Al-Thani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"El Deeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0317-8448","authenticated-orcid":false,"given":"Ahmed","family":"Al-Harrasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2026.345205_bib1","doi-asserted-by":"crossref","first-page":"240","DOI":"10.3390\/ph15020240","article-title":"Chiral switch: between therapeutical benefit and marketing strategy","volume":"15","author":"Hancu","year":"2022","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.aca.2026.345205_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2023.464214","article-title":"Recent advances in chiral selectors immobilization and chiral mobile phase additives in liquid chromatographic enantio-separations: a review","volume":"1706","author":"Ibrahim","year":"2023","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2026.345205_bib3","doi-asserted-by":"crossref","first-page":"760","DOI":"10.2174\/156802611795165098","article-title":"The significance of chirality in drug design and development","volume":"11","author":"Brooks","year":"2011","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.aca.2026.345205_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2021.462714","article-title":"A polymer-based monolithic capillary column with Polymyxin-B chiral selector for the enantioselective nano-high performance liquid chromatographic pharmaceutical analysis","volume":"1662","author":"Ghanem","year":"2022","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2026.345205_bib5","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jpba.2017.07.008","article-title":"The market of chiral drugs: chiral switches versus de novo enantiomerically pure compounds","volume":"147","author":"Calcaterra","year":"2018","journal-title":"J. Pharmaceut. Biomed. Anal."},{"key":"10.1016\/j.aca.2026.345205_bib6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/chir.23046","article-title":"Enantiomeric assay of escitalopram S(+)-enantiomer and its \u201cin-process impurities\u201d using two different techniques","volume":"31","author":"Soliman","year":"2019","journal-title":"Chirality"},{"key":"10.1016\/j.aca.2026.345205_bib7","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1007\/s00706-021-02832-5","article-title":"An overview of chiral separations of pharmaceutically active substances by HPLC (2018\u20132020)","volume":"152","author":"Grybinik","year":"2021","journal-title":"Monatshefte f\u00fcr Chemie - Chemical Monthly"},{"key":"10.1016\/j.aca.2026.345205_bib8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/jssc.202100593","article-title":"Recent progress in the development of chiral stationary phases for high-performance liquid chromatography","volume":"45","author":"Zhang","year":"2022","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.aca.2026.345205_bib9","doi-asserted-by":"crossref","first-page":"865","DOI":"10.3390\/molecules24050865","article-title":"Chiral stationary phases for liquid chromatography: recent developments","volume":"24","author":"Teixeira","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.aca.2026.345205_bib10","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1002\/elps.201800126","article-title":"Zwitterionic codeine-derived methacrylate monoliths for enantioselective capillary electrochromatography of chiral acids and chiral bases","volume":"39","author":"Carrasco-Correa","year":"2018","journal-title":"Electrophoresis"},{"key":"10.1016\/j.aca.2026.345205_bib11","doi-asserted-by":"crossref","unstructured":"K. Kacprzak, E. Wojaczy\u0144ska, A. Trochimczuk, F. Steppeler, J. Wojaczy\u0144ski, Alkaloids as chiral building blocks, Auxiliaries, Ligands, and Molecular Diversity, Chiral Building Blocks in Asymmetric Synthesis2022, pp. 297-366.","DOI":"10.1002\/9783527834204.ch10"},{"key":"10.1016\/j.aca.2026.345205_bib12","doi-asserted-by":"crossref","first-page":"5241","DOI":"10.3390\/molecules26175241","article-title":"Chiral monolithic silica-based HPLC columns for enantiomeric separation and determination: functionalization of chiral selector and recognition of selector-selectand interaction","volume":"26","author":"Asmari","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.aca.2026.345205_bib13","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1080\/10408347.2023.2224442","article-title":"Macrocyclic antibiotics as effective chiral selectors in liquid chromatography for enantiomeric separation of pharmaceutical compounds: a review","volume":"54","author":"Fouad","year":"2024","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.aca.2026.345205_bib14","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0021-9673(01)95006-X","article-title":"Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases: III. Optical resolution of a series of N-aroyl d,l-amino acids by high-performance liquid chromatography on bovine serum albumin covalently bound to silica","volume":"264","author":"Allenmark","year":"1983","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2026.345205_bib15","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0021-9673(01)90787-3","article-title":"Direct liquid chromatographic resolution of racemic drugs using \u03b11-acid glycoprotein as the chiral stationary phase","volume":"269","author":"Hermansson","year":"1983","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.aca.2026.345205_bib16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3390\/separations3030027","article-title":"Chromatographic studies of protein-based chiral separations","volume":"3","author":"Bi","year":"2016","journal-title":"Separations"},{"key":"10.1016\/j.aca.2026.345205_bib17","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3390\/chemosensors9110304","article-title":"Enantioresolution and binding affinity studies on human serum albumin: recent applications and trends","volume":"9","author":"Cardoso","year":"2021","journal-title":"Chemosensors"},{"key":"10.1016\/j.aca.2026.345205_bib18","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.3390\/molecules29061346","article-title":"Comprehensive review on chiral stationary phases in single-column simultaneous chiral\u2013achiral HPLC separation methods","author":"Papp","year":"2024","journal-title":"Molecules"},{"key":"10.1016\/j.aca.2026.345205_bib19","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1080\/10408398.2017.1381583","article-title":"Lactoferrin: structure, function, denaturation and digestion","volume":"59","author":"Wang","year":"2019","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.aca.2026.345205_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.141639","article-title":"Exploring the binding mechanism and functional properties of lactoferrin-berberine complex: based on multispectral analysis, molecular docking, and dynamics simulations","volume":"464","author":"Wu","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.aca.2026.345205_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.112079","article-title":"An electrochemical immunosensor based on AgNPs\/Nafion-GCE for detection of salivary lactoferrin: alzheimer's disease biomarker","volume":"207","author":"Rabbani","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2026.345205_bib22","doi-asserted-by":"crossref","first-page":"4604","DOI":"10.3390\/molecules27144604","article-title":"Microscale thermophoresis and molecular modelling to explore the chelating drug transportation in the milk to infant","volume":"27","author":"Asmari","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.aca.2026.345205_bib23","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/j.idairyj.2006.06.013","article-title":"Lactoferrin research, technology and applications","volume":"16","author":"Wakabayashi","year":"2006","journal-title":"Int. Dairy J."},{"key":"10.1016\/j.aca.2026.345205_bib24","article-title":"Lactoferrin: current situation and future prospects","volume":"62","author":"Hu","year":"2024","journal-title":"Food Biosci."},{"key":"10.1016\/j.aca.2026.345205_bib25","article-title":"Experimental design utilizing mixed micellar monolithic liquid chromatography and ethanol for rapid simultaneous determination of four antipsoriatics: a blue\u2013green approach","volume":"8","author":"Alamir","year":"2025","journal-title":"Sep. Sci."},{"key":"10.1016\/j.aca.2026.345205_bib26","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.foodres.2017.12.016","article-title":"Effect of technological treatments on bovine lactoferrin: an overview","volume":"106","author":"Franco","year":"2018","journal-title":"Food Res. Int."},{"key":"10.1016\/j.aca.2026.345205_bib27","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1002\/jssc.200500171","article-title":"Chararacterization of a monolithic immobilized trypsin microreactor with on-line coupling to ESI-MS","volume":"28","author":"K\u0159venkov\u00e1","year":"2005","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.aca.2026.345205_bib28","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.talanta.2010.06.041","article-title":"High-performance affinity monolith chromatography for chiral separation and determination of enzyme kinetic constants","volume":"82","author":"Yao","year":"2010","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2026.345205_bib29","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.talanta.2012.01.039","article-title":"Monoliths with proteins as chiral selectors for enantiomer separation","volume":"91","author":"Zheng","year":"2012","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2026.345205_bib30","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3390\/ph14020098","article-title":"Immobilization of chondroitin sulfate A onto monolithic epoxy silica column as a new chiral stationary phase for high-performance liquid chromatographic enantioseparation","volume":"14","author":"Ratih","year":"2021","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.aca.2026.345205_bib31","unstructured":"A.K. Sharma, Singh, T.P., Crystal Structure of a Complex of Lactoferrin with a Lanthanide Ion (SM3+) at 3.4 Angstrom Resolution, PDB."},{"key":"10.1016\/j.aca.2026.345205_bib32","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1758-2946-3-33","article-title":"Open babel: an open chemical toolbox","volume":"3","author":"O'Boyle","year":"2011","journal-title":"J. Cheminf."},{"key":"10.1016\/j.aca.2026.345205_bib33","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/jcc.21256","article-title":"AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility","volume":"30","author":"Morris","year":"2009","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.aca.2026.345205_bib34","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jpba.2007.03.017","article-title":"Development of an affinity silica monolith containing human serum albumin for chiral separations","volume":"46","author":"Mallik","year":"2008","journal-title":"J. Pharmaceut. Biomed. Anal."},{"key":"10.1016\/j.aca.2026.345205_bib35","doi-asserted-by":"crossref","first-page":"6663","DOI":"10.3390\/molecules28186663","article-title":"Lipase as a chiral selector immobilised on carboxylated single-walled carbon nanotubes and encapsulated in the organic polymer monolithic capillary for nano-high performance liquid chromatography enantioseparation of racemic pharmaceuticals","volume":"28","author":"Fouad","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.aca.2026.345205_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0236837","article-title":"Experimental evaluation of oil recovery mechanism using a variety of surface-modified silica nanoparticles: role of in-situ surface-modification in oil-wet system","volume":"15","author":"Adil","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.aca.2026.345205_bib37","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.bbabio.2007.06.004","article-title":"Infrared spectroscopy of proteins","volume":"1767","author":"Barth","year":"2007","journal-title":"Biochim. Biophys. Acta Bioenerg."},{"key":"10.1016\/j.aca.2026.345205_bib38","doi-asserted-by":"crossref","first-page":"8572","DOI":"10.1021\/acsomega.9b04421","article-title":"DFT-calculated IR spectrum amide I, II, and III band contributions of N-Methylacetamide fine components","volume":"5","author":"Ji","year":"2020","journal-title":"ACS Omega"},{"key":"10.1016\/j.aca.2026.345205_bib39","doi-asserted-by":"crossref","first-page":"8771","DOI":"10.1021\/bi00489a038","article-title":"Determination of the secondary structure content of proteins in aqueous solutions from their amide I and amide II infrared bands. Comparison between classical and partial least-squares methods","volume":"29","author":"Dousseau","year":"1990","journal-title":"Biochemistry"},{"key":"10.1016\/j.aca.2026.345205_bib40","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1128\/AAC.00908-09","article-title":"Structure-microbicidal activity relationship of synthetic fragments derived from the antibacterial \u03b1-helix of human lactoferrin","volume":"54","author":"Haversen","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.aca.2026.345205_bib41","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1021\/la103826p","article-title":"Evaluating glutamate and aspartate binding mechanisms to rutile (\u03b1-TiO2) via ATR-FTIR spectroscopy and quantum chemical calculations","volume":"27","author":"Parikh","year":"2011","journal-title":"Langmuir"},{"key":"10.1016\/j.aca.2026.345205_bib42","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.3390\/ijms24032168","article-title":"Enantioselective human serum albumin binding of apremilast: liquid chromatographic, fluorescence and molecular docking study","volume":"24","author":"Dombi","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.aca.2026.345205_bib43","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.4155\/bio-2019-0074","article-title":"Recognition mechanisms and binding of xanthones on human serum albumin by liquid chromatography","volume":"11","author":"do Carmo","year":"2019","journal-title":"Bioanalysis"},{"key":"10.1016\/j.aca.2026.345205_bib44","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.idairyj.2010.02.003","article-title":"A comparison of effects of pH on the thermal stability and conformation of caprine and bovine lactoferrin","volume":"20","author":"Sreedhara","year":"2010","journal-title":"Int. Dairy J."},{"key":"10.1016\/j.aca.2026.345205_bib45","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s41664-022-00222-2","article-title":"Recent advances on chiral Mobile phase additives: a critical review","volume":"6","author":"Li","year":"2022","journal-title":"Journal of Analysis and Testing"},{"key":"10.1016\/j.aca.2026.345205_bib46","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0378-4347(00)00267-X","article-title":"Chiral separation by simultaneous use of vancomycin as stationary phase chiral selector and chiral mobile phase additive","volume":"745","author":"Sun","year":"2000","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1016\/j.aca.2026.345205_bib47","doi-asserted-by":"crossref","first-page":"200","DOI":"10.2174\/1573412914666180518105046","article-title":"Enantioseparation of cinacalcet, and its two related compounds by HPLC with self-made chiral stationary phases and chiral mobile phase additives","volume":"15","author":"Yang","year":"2019","journal-title":"Curr. Pharmaceut. Anal."},{"key":"10.1016\/j.aca.2026.345205_bib48","doi-asserted-by":"crossref","first-page":"4141","DOI":"10.5012\/bkcs.2012.33.12.4141","article-title":"The influence of temperature, ultrasonication and chiral mobile phase additives on chiral separation: predominant influence of \u03b2-cyclodextrin chiral mobile phase additive under ultrasonic irradiation","volume":"33","author":"Lee","year":"2012","journal-title":"Bull. Kor. Chem. Soc."},{"key":"10.1016\/j.aca.2026.345205_bib49","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.microc.2019.04.059","article-title":"Assessment and validation of green stability indicating RP-HPLC method for simultaneous determination of timolol and latanoprost in pharmaceutical dosage forms using eco-friendly chiral mobile phase","volume":"148","author":"Ibrahim","year":"2019","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2026.345205_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2019.115639","article-title":"Chiral recognition in separation sciences. Part I: polysaccharide and cyclodextrin selectors","volume":"120","author":"Scriba","year":"2019","journal-title":"TrAC, Trends Anal. Chem."},{"key":"10.1016\/j.aca.2026.345205_bib51","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.3762\/bjoc.9.133","article-title":"Space filling of \u03b2-cyclodextrin and \u03b2-cyclodextrin derivatives by volatile hydrophobic guests","volume":"9","author":"Fourmentin","year":"2013","journal-title":"Beilstein J. Org. Chem."},{"key":"10.1016\/j.aca.2026.345205_bib52","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1007\/s43450-024-00554-3","article-title":"Polypogon monspeliensis hepatoprotective attributes: UHPLC\/QTOF-MS\/MS metabolite profiling and in vitro and in silico studies","volume":"34","author":"Abbass","year":"2024","journal-title":"Revista Brasileira de Farmacognosia"},{"key":"10.1016\/j.aca.2026.345205_bib53","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1002\/jssc.200900051","article-title":"HSA binding of HIV protease inhibitors: a high-performance affinity chromatography study","volume":"32","author":"Bertucci","year":"2009","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.aca.2026.345205_bib54","doi-asserted-by":"crossref","first-page":"19562","DOI":"10.3390\/ijms151119562","article-title":"Competing intramolecular vs. intermolecular hydrogen bonds in solution","volume":"15","author":"Nagy","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.aca.2026.345205_bib55","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.chroma.2005.08.028","article-title":"Impact of methanol and acetonitrile on separations based on \u03c0\u2013\u03c0 interactions with a reversed-phase phenyl column","volume":"1097","author":"Yang","year":"2005","journal-title":"J. Chromatogr. A"}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026001558?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026001558?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T12:10:34Z","timestamp":1789733434000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267026001558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":55,"alternative-id":["S0003267026001558"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2026.345205","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploring lactoferrin as an innovative covalently immobilized chiral selector for the selective separation of pharmaceutical enantiomers using HPLC","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2026.345205","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"345205"}}