{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:14:14Z","timestamp":1790651654099,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22404068"],"award-info":[{"award-number":["22404068"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.aca.2026.345220","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:17:54Z","timestamp":1770682674000},"page":"345220","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["COF-Zincon dual signal amplification: A sensitive real-time electrochemical sensor for Zn2+ detection towards anxiety disorder diagnosis"],"prefix":"10.1016","volume":"1394","author":[{"given":"Honglong","family":"Zou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonggui","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghui","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifu","family":"Ai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhui","family":"Ping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youhui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihui","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2026.345220_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpr.2022.102162","article-title":"Characteristics of episodic future thinking in anxiety: a systematic review and meta-analysis","volume":"95","author":"Du","year":"2022","journal-title":"Clin. Psychol. Rev."},{"key":"10.1016\/j.aca.2026.345220_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpr.2020.101894","article-title":"Anxiety disorders and healthcare utilization: a systematic review","volume":"81","author":"Horenstein","year":"2020","journal-title":"Clin. Psychol. Rev."},{"issue":"23","key":"10.1016\/j.aca.2026.345220_bib3","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1056\/NEJMcp1614701","article-title":"Social anxiety disorder","volume":"376","author":"Leichsenring","year":"2017","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.aca.2026.345220_bib4","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/gut.39.4.551","article-title":"Intestinal transit in anxiety and depression","volume":"39","author":"Gorard","year":"1996","journal-title":"Gut"},{"issue":"10277","key":"10.1016\/j.aca.2026.345220_bib5","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S0140-6736(21)00359-7","article-title":"Anxiety disorders","volume":"397","author":"Penninx","year":"2021","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.aca.2026.345220_bib6","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/wps.20798","article-title":"COVID-19 health anxiety","volume":"19","author":"Tyrer","year":"2020","journal-title":"World Psychiatry"},{"issue":"1","key":"10.1016\/j.aca.2026.345220_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbr.2006.11.023","article-title":"Anxiety-like behavior of young rats after 2-week zinc deprivation","volume":"177","author":"Takeda","year":"2007","journal-title":"Behav. Brain Res."},{"issue":"5","key":"10.1016\/j.aca.2026.345220_bib8","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1093\/nutrit\/nuad076","article-title":"A systematic review of the association between zinc and anxiety","volume":"82","author":"Azargoonjahromi","year":"2024","journal-title":"Nutr. Rev."},{"issue":"1","key":"10.1016\/j.aca.2026.345220_bib9","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-15080-2","article-title":"Zinc nutritional status, mood states and quality of life in diarrhea-predominant irritable bowel syndrome: a case-control study","volume":"12","author":"Rezazadegan","year":"2022","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.aca.2026.345220_bib10","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s12011-013-9723-7","article-title":"Comparative analysis of serum zinc, copper, manganese, iron, calcium, and magnesium level and complexity of interelement relations in generalized anxiety disorder patients","volume":"154","author":"Islam","year":"2013","journal-title":"Biol. Trace Elem. Res."},{"issue":"5","key":"10.1016\/j.aca.2026.345220_bib11","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1111\/nph.19070","article-title":"A vacuolar transporter plays important roles in zinc and cadmium accumulation in rice grain","volume":"239","author":"Ning","year":"2023","journal-title":"New Phytol."},{"issue":"11","key":"10.1016\/j.aca.2026.345220_bib12","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1007\/s10661-023-11965-5","article-title":"Estimation of selected elemental impurities by inductively coupled plasma-mass spectroscopy (ICP-MS) in commercial and fresh fruit juices","volume":"195","author":"James","year":"2023","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.aca.2026.345220_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.146258","article-title":"Enhanced dual-mode electrochemical zinc ion sensing by electric field-driven bi-directional mass transport","volume":"475","author":"Huang","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.345220_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.137433","article-title":"A dual-mode electrochemical and electrochemiluminescent sensor based on hydrogen-bonded organic frameworks for highly sensitive detection of mercury and zinc ions","volume":"431","author":"Yan","year":"2025","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.aca.2026.345220_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115409","article-title":"Development of electrochemical Zn2+ sensors for rapid voltammetric detection of glucose-stimulated insulin release from pancreatic beta-cells","volume":"235","author":"Vanderlaan","year":"2023","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2026.345220_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.138500","article-title":"Simultaneous electrochemical sensing of heavy metal ions (Zn2+, Cd2+, Pb2+, and Hg2+) in food samples using a covalent organic framework\/carbon black modified glassy carbon electrode","volume":"442","author":"Mirzaei Karazan","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.aca.2026.345220_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2025.143362","article-title":"Simultaneous detection of heavy metal ions in food samples using a hypersensitive electrochemical sensor based on APTES-incubated MXene-NH2@CeFe-MOF-NH2","volume":"475","author":"Shi","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.aca.2026.345220_bib18","article-title":"Multiplexed electrochemical assays for clinical applications","volume":"39","author":"Sharafeldin","year":"2023","journal-title":"Curr. Opin. Electrochem."},{"key":"10.1016\/j.aca.2026.345220_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.127575","article-title":"Electrochemical investigations for COVID-19 detection-A comparison with other viral detection methods","volume":"420","author":"Bukkitgar","year":"2021","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.345220_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.fbio.2025.106118","article-title":"A label-free electrochemical aptasensor combined Au\/Ag@ZIF-8 and dual amplification strategy for sensitive detection of \u03b2-lactoglobulin","volume":"65","author":"Lu","year":"2025","journal-title":"Food Biosci."},{"key":"10.1016\/j.aca.2026.345220_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.153596","article-title":"Highly conductive AuNPs\/Co-MOF nanocomposites synergistic hybridization chain reaction enzyme-free electrochemical aptasensor for ultrasensitive detection of Aflatoxin B1","volume":"495","author":"Yu","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"44","key":"10.1016\/j.aca.2026.345220_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202006277","article-title":"Functional porous materials chemistry","volume":"32","author":"Yu","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.aca.2026.345220_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2023.117488","article-title":"Recent advances in analytical sensing detection of heavy metal ions based on covalent organic frameworks nanocomposites","volume":"171","author":"Li","year":"2024","journal-title":"TrAC, Trends Anal. Chem."},{"issue":"12","key":"10.1016\/j.aca.2026.345220_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202407436","article-title":"Linkage engineering of semiconductive covalent-organic frameworks toward room-temperature ppb-level selective ammonia sensing","volume":"21","author":"Yan","year":"2025","journal-title":"Small"},{"issue":"43","key":"10.1016\/j.aca.2026.345220_bib25","doi-asserted-by":"crossref","first-page":"23727","DOI":"10.1021\/jacs.3c08256","article-title":"COF-coated microelectrode for space-confined electrochemical sensing of dopamine in Parkinson'S disease model mouse brain","volume":"145","author":"Zhou","year":"2023","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2026.345220_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.121470","article-title":"New insight into the mechanism of biofouling-resistant thiazole-linked covalent organic frameworks for selective uranium capture from seawater","volume":"255","author":"Zhao","year":"2024","journal-title":"Water Res."},{"issue":"9","key":"10.1016\/j.aca.2026.345220_bib27","doi-asserted-by":"crossref","DOI":"10.1002\/sstr.202500138","article-title":"Analysis and study of covalent organic frameworks in electrochemical sensors for water environment pollutant detection","volume":"6","author":"Long","year":"2025","journal-title":"Small Struct."},{"issue":"11","key":"10.1016\/j.aca.2026.345220_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2025.110844","article-title":"Ultrasensitive electrochemical sensor based on para-sulfonatocalix[4]arene functionalized gold nanoparticles for sulfamethazine detection","volume":"36","author":"Niu","year":"2025","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.aca.2026.345220_bib29","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.electacta.2017.12.162","article-title":"Biochar decorated with gold nanoparticles for electrochemical sensing application","volume":"261","author":"Xiang","year":"2018","journal-title":"Electrochim. Acta"},{"issue":"1","key":"10.1016\/j.aca.2026.345220_bib30","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1021\/acs.inorgchem.9b02848","article-title":"Coordination chemistry of a controlled burst of Zn2+ in bulk aqueous and nanosized water droplets with a zincon chelator","volume":"59","author":"Beuning","year":"2020","journal-title":"Inorg. Chem."},{"issue":"11","key":"10.1016\/j.aca.2026.345220_bib31","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/0039-9140(67)80214-5","article-title":"Studies on metallochromic indicators-II: zincon and its mercury and zinc complexes as indicators in EDTA titrations","volume":"14","author":"Singhal","year":"1967","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2026.345220_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2023.108772","article-title":"Application of Zincon analysis to investigate the zinc speciation in aqueous media for further understanding of ZnO solubility","volume":"191","author":"Kaya","year":"2023","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2026.345220_bib33","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.microc.2016.10.016","article-title":"A solid phase extraction flow injection spectrophotometric method for the zinc determination in plants","volume":"130","author":"Ribas","year":"2017","journal-title":"Microchem. J."},{"issue":"2","key":"10.1016\/j.aca.2026.345220_bib34","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/mp.2016.68","article-title":"Stress-induced structural plasticity of medial amygdala stellate neurons and rapid prevention by a candidate antidepressant","volume":"22","author":"Lau","year":"2017","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.aca.2026.345220_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2025.111518","article-title":"Astrocytic glucocorticoid receptors in the ventral hippocampus modulate anxiety-like behaviors","volume":"230","author":"Lu","year":"2025","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.aca.2026.345220_bib36","first-page":"818","volume":"vol. 8","author":"Li","year":"2025"},{"issue":"1","key":"10.1016\/j.aca.2026.345220_bib37","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.1038\/s41467-024-47266-9","article-title":"Stress increases hepatic release of lipocalin 2 which contributes to anxiety-like behavior in mice","volume":"15","author":"Yan","year":"2024","journal-title":"Nat. Commun."},{"issue":"9","key":"10.1016\/j.aca.2026.345220_bib38","doi-asserted-by":"crossref","first-page":"4149","DOI":"10.1002\/ptr.7876","article-title":"11-Ethoxyviburtinal improves chronic restraint stress-induced anxiety-like behaviors in gender-specific mice via PI3K\/Akt and E(2)\/ERbeta signaling pathways","volume":"37","author":"Lyu","year":"2023","journal-title":"Phytother Res."},{"issue":"3","key":"10.1016\/j.aca.2026.345220_bib39","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1002\/ptr.6900","article-title":"Anxiolytic activity of Psidium guajava in mice subjected to chronic restraint stress and effect on neurotransmitters in brain","volume":"35","author":"Sahoo","year":"2021","journal-title":"Phytother Res."},{"key":"10.1016\/j.aca.2026.345220_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.952941","article-title":"Organic zinc with moderate chelation strength enhances zinc absorption in the small intestine and expression of related transporters in the duodenum of broilers","volume":"13","author":"Hu","year":"2022","journal-title":"Front. Physiol."},{"issue":"2","key":"10.1016\/j.aca.2026.345220_bib41","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1021\/acs.jafc.9b07097","article-title":"Prevention of zinc precipitation with calcium phosphate by casein hydrolysate improves zinc absorption in mouse small intestine ex vivo via a nanoparticle-mediated mechanism","volume":"68","author":"Feng","year":"2020","journal-title":"J. Agric. Food Chem."},{"issue":"22","key":"10.1016\/j.aca.2026.345220_bib42","doi-asserted-by":"crossref","first-page":"3934","DOI":"10.3390\/nu16223934","article-title":"Dietary zinc restriction and chronic restraint stress affect mice physiology, immune organ morphology, and liver function","volume":"16","author":"Bederska-\u0141ojewska","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.aca.2026.345220_bib43","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1471-230X-14-32","article-title":"Psychological stress induced zinc accumulation and up-regulation of ZIP14 and metallothionein in rat liver","volume":"14","author":"Tian","year":"2014","journal-title":"BMC Gastroenterol."},{"key":"10.1016\/j.aca.2026.345220_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2023.114343","article-title":"Diazepam effects on anxiety-related defensive behavior of male and female high and low open-field activity inbred mouse strains","volume":"271","author":"Mehrhoff","year":"2023","journal-title":"Physiol. Behav."},{"issue":"1","key":"10.1016\/j.aca.2026.345220_bib45","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00213-022-06277-4","article-title":"Desulfovibrio confers resilience to the comorbidity of pain and anxiety in a mouse model of chronic inflammatory pain","volume":"240","author":"Wu","year":"2023","journal-title":"Psychopharmacologia"},{"issue":"12","key":"10.1016\/j.aca.2026.345220_bib46","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1002\/elan.201700406","article-title":"Electrochemical determination of fenitrothion organophosphorus pesticide using polyzincon modified-glassy carbon electrode","volume":"29","author":"Ensafi","year":"2017","journal-title":"Electroanalysis"},{"key":"10.1016\/j.aca.2026.345220_bib47","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jelechem.2018.12.002","article-title":"Electrochemical detection of mobile zinc ions for early diagnosis of prostate cancer","volume":"833","author":"Teng","year":"2019","journal-title":"J. Electroanal. Chem."},{"issue":"10","key":"10.1016\/j.aca.2026.345220_bib48","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1002\/elan.201300158","article-title":"The application of nafion metal catalyst free carbon nanotube modified gold electrode: voltammetric zinc detection in serum","volume":"25","author":"Yue","year":"2013","journal-title":"Electroanalysis"},{"issue":"34","key":"10.1016\/j.aca.2026.345220_bib49","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.1039\/D4CC00619D","article-title":"Exploiting halide perovskites for heavy metal ion detection","volume":"60","author":"Tang","year":"2024","journal-title":"Chem. Commun."},{"issue":"30","key":"10.1016\/j.aca.2026.345220_bib50","doi-asserted-by":"crossref","first-page":"18987","DOI":"10.1021\/acsomega.0c02279","article-title":"ElectroSens platform with a polyelectrolyte-based carbon fiber sensor for point-of-care analysis of Zn in blood and urine","volume":"5","author":"Nikolaev","year":"2020","journal-title":"ACS Omega"},{"issue":"3","key":"10.1016\/j.aca.2026.345220_bib51","doi-asserted-by":"crossref","first-page":"900","DOI":"10.3390\/s22030900","article-title":"On the electroanalytical detection of Zn ions by a novel schiff base ligand-spce sensor","volume":"22","author":"Bressi","year":"2022","journal-title":"Sensors"},{"key":"10.1016\/j.aca.2026.345220_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.111467","article-title":"Screen-printed electrodes decorated with low content Pt\u2013Ni microstructures for sensitive detection of Zn(II), ascorbic acid and paracetamol in pharmaceutical products and human blood samples","volume":"206","author":"Makhlouf","year":"2024","journal-title":"Microchem. J."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026001704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026001704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:16:28Z","timestamp":1777392988000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267026001704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":52,"alternative-id":["S0003267026001704"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2026.345220","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"COF-Zincon dual signal amplification: A sensitive real-time electrochemical sensor for Zn2+ detection towards anxiety disorder diagnosis","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2026.345220","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"345220"}}