{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:24:41Z","timestamp":1786983881560,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012502","name":"Collaborative Innovation Center for Water Treatment Technology and Materials","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012502","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22176075"],"award-info":[{"award-number":["22176075"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22476072"],"award-info":[{"award-number":["22476072"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.aca.2026.345400","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:43:15Z","timestamp":1773391395000},"page":"345400","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["A label-free fluorescent aptasensor based on DNA-templated silver nanoclusters and catalytic hairpin assembly for highly specific detection of Escherichia coli O111:B4 lipopolysaccharide"],"prefix":"10.1016","volume":"1402","author":[{"given":"Ying","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanmengyi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxia","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4926-347X","authenticated-orcid":false,"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2026.345400_bib1","article-title":"Highly sensitive detection of lipopolysaccharides using an aptasensor based on hybridization chain reaction","volume":"6","author":"Xie","year":"2016","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.aca.2026.345400_bib2","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3390\/gastroent12010004","article-title":"Enteropathogenic Escherichia coli\u2014A summary of the literature","volume":"12","author":"Mare","year":"2021","journal-title":"Gastroenterol. Insights"},{"issue":"2","key":"10.1016\/j.aca.2026.345400_bib3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00604-018-3212-9","article-title":"Colorimetric detection and typing of E. coli lipopolysaccharides based on a dual aptamer-functionalized gold nanoparticle probe","volume":"186","author":"Zhu","year":"2019","journal-title":"Mikrochim. Acta"},{"issue":"11","key":"10.1016\/j.aca.2026.345400_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0048999","article-title":"An aptamer-based biosensor for colorimetric detection of Escherichia coli O157:H7","volume":"7","author":"Wu","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.aca.2026.345400_bib5","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/elan.201200453","article-title":"Aptamer\u2010assisted gold Nanoparticles\/PEDOT platform for ultrasensitive detection of LPS","volume":"25","author":"Su","year":"2013","journal-title":"Electroanalysis"},{"issue":"15","key":"10.1016\/j.aca.2026.345400_bib6","doi-asserted-by":"crossref","first-page":"6685","DOI":"10.1021\/ja211570a","article-title":"Copolythiophene-derived colorimetric and fluorometric sensor for visually supersensitive determination of lipopolysaccharide","volume":"134","author":"Lan","year":"2012","journal-title":"J. Am. Chem. Soc."},{"issue":"8","key":"10.1016\/j.aca.2026.345400_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/s18082518","article-title":"Application of aptamer-based biosensor for rapid detection of pathogenic Escherichia coli","volume":"18","author":"Zhao","year":"2018","journal-title":"Sensors (Basel)"},{"key":"10.1016\/j.aca.2026.345400_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2025.343926","article-title":"Ultrasensitive electrochemical sensor for lipopolysaccharide detection catalyzed by 3,4,9,10-perylenetetracarboxylic diimide","volume":"1352","author":"Yu","year":"2025","journal-title":"Anal. Chim. Acta"},{"issue":"12","key":"10.1016\/j.aca.2026.345400_bib9","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s00604-019-3957-9","article-title":"A glassy carbon electrode modified with reduced graphene oxide and gold nanoparticles for electrochemical aptasensing of lipopolysaccharides from Escherichia coli bacteria","volume":"186","author":"Pourmadadi","year":"2019","journal-title":"Mikrochim. Acta"},{"issue":"Pt 2","key":"10.1016\/j.aca.2026.345400_bib10","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.bios.2016.10.012","article-title":"A rapid and visual aptasensor for Lipopolysaccharides detection based on the bulb-like triplex turn-on switch coupled with HCR-HRP nanostructures","volume":"89","author":"Xu","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2026.345400_bib11","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.snb.2017.10.004","article-title":"Terminal deoxynucleotidyl transferase-induced DNAzyme nanowire sensor for colorimetric detection of lipopolysaccharides","volume":"256","author":"Miao","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.aca.2026.345400_bib12","doi-asserted-by":"crossref","DOI":"10.1021\/ac050333k","article-title":"Use of an antimicrobial protein for Endotoxin detection in a competitive electrochemical assay","volume":"77","author":"Priano","year":"2005","journal-title":"Anal. Chem."},{"issue":"10","key":"10.1016\/j.aca.2026.345400_bib13","doi-asserted-by":"crossref","first-page":"5218","DOI":"10.1021\/acs.analchem.6b00276","article-title":"Ultrasensitive lipopolysaccharides detection based on Doxorubicin conjugated N-(Aminobutyl)-N-(ethylisoluminol) as electrochemiluminescence indicator and self-assembled tetrahedron DNA dendrimers as nanocarriers","volume":"88","author":"Xie","year":"2016","journal-title":"Anal. Chem."},{"issue":"25","key":"10.1016\/j.aca.2026.345400_bib14","doi-asserted-by":"crossref","first-page":"9720","DOI":"10.1021\/ja204013u","article-title":"Peptide functionalized polydiacetylene liposomes act as a fluorescent turn-on sensor for bacterial lipopolysaccharide","volume":"133","author":"Wu","year":"2011","journal-title":"J. Am. Chem. Soc."},{"issue":"4","key":"10.1016\/j.aca.2026.345400_bib15","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12223-008-0046-6","article-title":"In vitro antibacterial effects of antilipopolysaccharide DNA Aptamer\u2013C1qrs complexes","volume":"53","author":"Bruno","year":"2008","journal-title":"Folia Microbiol."},{"issue":"1","key":"10.1016\/j.aca.2026.345400_bib16","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.bios.2011.11.009","article-title":"Determination of endotoxin through an aptamer-based impedance biosensor","volume":"32","author":"Su","year":"2012","journal-title":"Biosens. Bioelectron."},{"issue":"5","key":"10.1016\/j.aca.2026.345400_bib17","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1002\/elan.201100700","article-title":"A rapid and sensitive aptamer\u2010based electrochemical biosensor for direct detection of Escherichia Coli O111","volume":"24","author":"Luo","year":"2012","journal-title":"Electroanalysis"},{"issue":"11","key":"10.1016\/j.aca.2026.345400_bib18","doi-asserted-by":"crossref","first-page":"12301","DOI":"10.1021\/acsnano.9b06522","article-title":"Aptamers as modular components of therapeutic nucleic acid nanotechnology","volume":"13","author":"Panigaj","year":"2019","journal-title":"ACS Nano"},{"issue":"2","key":"10.1016\/j.aca.2026.345400_bib19","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s41061-020-0283-y","article-title":"Aptamer-Functionalized DNA nanostructures for biological applications","volume":"378","author":"Fu","year":"2020","journal-title":"Top. Curr. Chem."},{"issue":"9","key":"10.1016\/j.aca.2026.345400_bib20","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1039\/C5CS00645G","article-title":"Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy","volume":"45","author":"Meng","year":"2016","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.aca.2026.345400_bib21","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.copbio.2016.11.020","article-title":"Aptamer-based environmental biosensors for small molecule contaminants","volume":"45","author":"Nguyen","year":"2017","journal-title":"Curr. Opin. Biotechnol."},{"issue":"25","key":"10.1016\/j.aca.2026.345400_bib22","doi-asserted-by":"crossref","first-page":"10391","DOI":"10.1021\/acs.analchem.4c01554","article-title":"Programmable DNA templates for silver nanoclusters synthesis to develop On-Demand FRET aptasensor","volume":"96","author":"Liu","year":"2024","journal-title":"Anal. Chem."},{"issue":"13","key":"10.1016\/j.aca.2026.345400_bib23","doi-asserted-by":"crossref","first-page":"14953","DOI":"10.1021\/acsami.1c24547","article-title":"Multibranched linear DNA-controlled assembly of silver nanoclusters and their applications in aptamer-based cell recognition","volume":"14","author":"Wu","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.aca.2026.345400_bib24","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.snb.2018.08.078","article-title":"DNA-templated fluorescent silver nanoclusters for sensitive detection of pathogenic bacteria based on MNP-DNAzyme-AChE complex","volume":"276","author":"Zheng","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"10.1016\/j.aca.2026.345400_bib25","first-page":"5207","article-title":"DNA-templated Ag nanocluster formation","volume":"126","author":"Jeffrey","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2026.345400_bib26","doi-asserted-by":"crossref","first-page":"5038","DOI":"10.1021\/ja8005644","article-title":"Oligonucleotide-stabilized Ag nanocluster fluorophores","volume":"130","author":"Richards","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2026.345400_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113871","article-title":"Amplifiable ratiometric fluorescence biosensing of nanosilver multiclusters populated in three-way-junction DNA branches","volume":"199","author":"Yang","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2026.345400_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116911","article-title":"A fluorescence and colorimetric dual-mode aptasensor for kanamycin detection","volume":"268","author":"Tian","year":"2025","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2026.345400_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111610","article-title":"Label-free and ultrasensitive electrochemical biosensor for the detection of EBV-Related DNA based on AgDNCs@DNA\/AgNCs nanocomposites and lambda exonuclease-assisted target recycling","volume":"143","author":"Que","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.aca.2026.345400_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2023.135216","article-title":"An enzyme-free and label-free ratiometric fluorescence signal amplification biosensor based on DNA-silver nanoclusters and catalytic hairpin assembly for tetracycline detection","volume":"404","author":"Yang","year":"2024","journal-title":"Sens. Actuators, B"},{"issue":"37","key":"10.1016\/j.aca.2026.345400_bib31","doi-asserted-by":"crossref","first-page":"32089","DOI":"10.1021\/acsami.7b09034","article-title":"Ratiometric catalyzed-assembly of NanoCluster beacons: a nonenzymatic approach for amplified DNA detection","volume":"9","author":"Ge","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"8","key":"10.1016\/j.aca.2026.345400_bib32","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1021\/nl101773c","article-title":"A DNA--silver nanocluster probe that fluoresces upon hybridization","volume":"10","author":"Yeh","year":"2010","journal-title":"Nano Lett."},{"key":"10.1016\/j.aca.2026.345400_bib33","first-page":"4229","article-title":"Hairpins with Poly-C loops stabilize four types of Fluorescent Agn:DNA","volume":"113","author":"O'Neill","year":"2009","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"10.1016\/j.aca.2026.345400_bib34","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1021\/acs.langmuir.5b03934","article-title":"Changes in spectra and conformation of hairpin DNA-stabilized silver nanoclusters induced by stem sequence perturbations","volume":"32","author":"Del Bonis-O'Donnell","year":"2016","journal-title":"Langmuir"},{"issue":"28","key":"10.1016\/j.aca.2026.345400_bib35","doi-asserted-by":"crossref","first-page":"25066","DOI":"10.1021\/acsami.9b08215","article-title":"A ratiometric fluorescent DNA radar based on contrary response of DNA\/silver nanoclusters and G-Quadruplex\/Crystal violet","volume":"11","author":"Wang","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"37","key":"10.1016\/j.aca.2026.345400_bib36","doi-asserted-by":"crossref","first-page":"12820","DOI":"10.1021\/ja505988g","article-title":"An \"enhanced PET\"-based fluorescent probe with ultrasensitivity for imaging basal and elesclomol-induced HClO in cancer cells","volume":"136","author":"Zhu","year":"2014","journal-title":"J. Am. Chem. Soc."},{"issue":"39","key":"10.1016\/j.aca.2026.345400_bib37","doi-asserted-by":"crossref","first-page":"14805","DOI":"10.1021\/acs.analchem.3c03151","article-title":"Fluorescent features and applicable biosensing of a core-shell Ag nanocluster shielded by a DNA tetrahedral nanocage","volume":"95","author":"He","year":"2023","journal-title":"Anal. Chem."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026003508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026003508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T04:10:43Z","timestamp":1779509443000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267026003508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":37,"alternative-id":["S0003267026003508"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2026.345400","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A label-free fluorescent aptasensor based on DNA-templated silver nanoclusters and catalytic hairpin assembly for highly specific detection of Escherichia coli O111:B4 lipopolysaccharide","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2026.345400","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"345400"}}