{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:09:59Z","timestamp":1789808999572,"version":"4.0.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31772053"],"award-info":[{"award-number":["31772053"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.aca.2026.346075","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:13:04Z","timestamp":1785885184000},"page":"346075","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["High-performance AIECL immunosensor based on V-TCPE metal-organic frameworks and CoMoO4@Au nanoflowers as co-reaction accelerator for ultrasensitive detection of T-2 toxin"],"prefix":"10.1016","volume":"1422","author":[{"given":"Huiling","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anping","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0520-7302","authenticated-orcid":false,"given":"Jianguo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2026.346075_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.toxicon.2025.108618","article-title":"Four-year surveillance of mycotoxins in feed and raw materials (2021-2024): occurrence, co-contamination, and risk implications","volume":"268","author":"Skrzydlewski","year":"2025","journal-title":"Toxicon"},{"key":"10.1016\/j.aca.2026.346075_bib2","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1021\/acs.jafc.4c10015","article-title":"T-2 toxin nephrotoxicity: toxic effects, mechanisms, mitigations, and future perspectives","volume":"73","author":"Wang","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2026.346075_bib3","doi-asserted-by":"crossref","first-page":"3441","DOI":"10.1021\/jf200767q","article-title":"T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods","volume":"59","author":"Li","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.aca.2026.346075_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.103471","article-title":"Pathological consequences, metabolism and toxic effects of trichothecene T-2 toxin in poultry","volume":"103","author":"V\u00f6r\u00f6sh\u00e1zi","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.aca.2026.346075_bib5","doi-asserted-by":"crossref","first-page":"481","DOI":"10.3390\/toxins15080481","article-title":"T-2 and HT-2 toxins: toxicity, occurrence and analysis: a review","volume":"15","author":"Meneely","year":"2023","journal-title":"Toxins"},{"key":"10.1016\/j.aca.2026.346075_bib6","doi-asserted-by":"crossref","first-page":"7754","DOI":"10.3390\/ijerph19137754","article-title":"Mycotoxin-linked mutations and cancer risk: a global health issue","volume":"19","author":"Ekwomadu","year":"2022","journal-title":"Int. J. Environ. Res. Pub. He."},{"key":"10.1016\/j.aca.2026.346075_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2024.117084","article-title":"SIRT5 safeguards against T-2 toxin induced liver injury by repressing iron accumulation, oxidative stress, and the activation of NLRP3 inflammasome","volume":"492","author":"Huang","year":"2024","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.aca.2026.346075_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2022.153324","article-title":"HIF-1\u03b1 inhibits T-2 toxin-mediated \u201cimmune evasion\u201d process by negatively regulating PD-1\/PD-L1","volume":"480","author":"You","year":"2022","journal-title":"Toxicology"},{"key":"10.1016\/j.aca.2026.346075_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2021.108120","article-title":"Contamination status of major mycotoxins in agricultural product and food stuff in Europe","volume":"127","author":"Luo","year":"2021","journal-title":"Food Control"},{"key":"10.1016\/j.aca.2026.346075_bib10","article-title":"An update on T2-toxins: metabolism, immunotoxicity mechanism and human assessment exposure of intestinal microbiota","volume":"8","author":"Zhang","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.aca.2026.346075_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxicon.2018.10.307","article-title":"Monoclonal antibody production and the development of an indirect competitive enzyme-linked immunosorbent assay for screening T-2 toxin in milk","volume":"156","author":"Xu","year":"2018","journal-title":"Toxicon"},{"key":"10.1016\/j.aca.2026.346075_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.113016","article-title":"Dual-signal point-of-care testing method for T-2 toxin utilizing target-responsive DNA hydrogel and starch iodide paper","volume":"210","author":"Deng","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2026.346075_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fsufs.2025.1659936","article-title":"Development of a ratiometric fluorescence immunoassay based on manganese dioxide nanosheets for the detection of T-2 toxin","volume":"9","author":"Ma","year":"2025","journal-title":"Front. Sustain. Food Syst."},{"key":"10.1016\/j.aca.2026.346075_bib14","doi-asserted-by":"crossref","first-page":"15482","DOI":"10.1021\/acs.analchem.5c02796","article-title":"Homogeneous hot spots plasmonic microcapsules integrated enrichment-detection All-in-One for sensitive and repeatable surface-enhanced raman spectroscopy analysis","volume":"97","author":"Li","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2026.346075_bib15","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jchromb.2016.02.035","article-title":"Determination for multiple mycotoxins in agricultural products using HPLC-MS\/MS via a multiple antibody immunoaffinity column","volume":"1021","author":"Zhang","year":"2016","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.aca.2026.346075_bib16","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.foodchem.2011.10.073","article-title":"Validation of a gas chromatography-electron capture detection of T-2 and HT-2 toxins in Chinese herbal medicines and related products after immunoaffinity column clean-up and pre-column derivatization","volume":"132","author":"Kong","year":"2012","journal-title":"Food Chem."},{"key":"10.1016\/j.aca.2026.346075_bib17","article-title":"Recent advances in electrochemiluminescence immunoassay based on multiple-signal strategy","volume":"28","author":"Du","year":"2021","journal-title":"Curr. Opin. Electrochem."},{"key":"10.1016\/j.aca.2026.346075_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202422578","article-title":"Smart flow micro\u2010reaction device integrated with oxygen reduction catalysts for gaseous electrochemiluminescence sensing","volume":"35","author":"Geng","year":"2025","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.aca.2026.346075_bib19","doi-asserted-by":"crossref","first-page":"12197","DOI":"10.1021\/jacs.4c02986","article-title":"Regulating reactive oxygen species over M-N\u2013C single-atom catalysts for potential-resolved electrochemiluminescence","volume":"146","author":"Zhou","year":"2024","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2026.346075_bib20","doi-asserted-by":"crossref","first-page":"885","DOI":"10.3390\/bioengineering11090885","article-title":"A novel high-throughput and sensitive electrochemiluminescence immunoassay system","volume":"11","author":"Liu","year":"2024","journal-title":"Bioengineering"},{"key":"10.1016\/j.aca.2026.346075_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.chempr.2025.102534","article-title":"Scintillators with aggregation-induced emission","volume":"11","author":"Yang","year":"2025","journal-title":"Chem"},{"key":"10.1016\/j.aca.2026.346075_bib22","doi-asserted-by":"crossref","first-page":"14605","DOI":"10.1021\/jacs.7b07710","article-title":"Aggregation-induced electrochemiluminescence of platinum (II) complexes","volume":"139","author":"Carrara","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.aca.2026.346075_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.161608","article-title":"Aggregation-induced electrochemiluminescence probe detects poisoning NOx for unveiling Pt catalyst deactivation and halogen ion activation effects during ammonia electro-oxidation","volume":"510","author":"Sun","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.346075_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.142661","article-title":"Highly sensitive aggregation-induced electrochemiluminescence sensor for cadmium detection in Ganoderma lucidum","volume":"470","author":"Xu","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.aca.2026.346075_bib25","doi-asserted-by":"crossref","first-page":"54012","DOI":"10.1021\/acsami.0c18197","article-title":"Aggregation-induced electrochemiluminescence of conjugated pdots containing a trace Ir(III) complex: insights into structure\u2013property relationships","volume":"12","author":"Gao","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.aca.2026.346075_bib26","doi-asserted-by":"crossref","first-page":"5441","DOI":"10.1021\/acs.analchem.2c00631","article-title":"Highly efficient aggregation-induced enhanced electrochemiluminescence of cyanophenyl-functionalized tetraphenylethene and its application in biothiols analysis","volume":"94","author":"Wang","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2026.346075_bib27","article-title":"Zirconium based metal\u2013organic frameworks with aggregation-induced electrochemiluminescence for sensitive analysis of aflatoxin B1 by signal dual-amplification strategy","volume":"500","author":"Li","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.346075_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2025.343639","article-title":"Facile preparation of iridium-based AIE polymer dots for sensitive electrochemiluminescence immunoassay of CD44 protein","volume":"1341","author":"Jia","year":"2025","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2026.346075_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136218","article-title":"Conjugated polymer-encapsulation-manipulated aggregation-induced electrochemiluminescence of tetraphenylethylene for sensitive malathion analysis","volume":"418","author":"He","year":"2024","journal-title":"Sensor. Actuat. B-Chem."},{"key":"10.1016\/j.aca.2026.346075_bib30","article-title":"Classification and research progress of aggregation-induced electrochemiluminescence materials for sensoring application","volume":"212","author":"Zhang","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2026.346075_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.137098","article-title":"Coordination-induced electrochemiluminescence of Zr-based metal-organic frameworks combined with an energy resonance transfer for sensitive analysis of acetamidine","volume":"426","author":"Ru","year":"2025","journal-title":"Sensor. Actuat. B-Chem."},{"key":"10.1016\/j.aca.2026.346075_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.155470","article-title":"Aggregation-induced electrochemiluminescence of an indium-based metal\u2013organic framework and resonance energy transfer strategy for the sensitive detection of \u03b22-microglobulin","volume":"498","author":"Hu","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.346075_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2023.133558","article-title":"Enhancing electrochemiluminescence by assembling ACQ ligands into Hf-based metal-organic framework nanosheet: a novel ECL emitter for fabricating ultrasensitive biosensor","volume":"382","author":"Gao","year":"2023","journal-title":"Sensor. Actuat. B-Chem."},{"key":"10.1016\/j.aca.2026.346075_bib34","article-title":"Dumbbell plate-shaped AIEgen-Based luminescent MOF with high quantum yield as self-enhanced ECL tags: mechanism insights and biosensing application","volume":"18","author":"Li","year":"2022","journal-title":"Small"},{"key":"10.1016\/j.aca.2026.346075_bib35","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jiec.2024.04.031","article-title":"One-pot vanadium-based organic frameworks for DEHP effective removal: relationships between the synthetic strategy, characterization, adsorption and solar-driven photocatalytic activity","volume":"138","author":"Zhang","year":"2024","journal-title":"J. Ind. Eng. Chem."},{"key":"10.1016\/j.aca.2026.346075_bib36","article-title":"Rational design of ionic V-MOF with confined Mo species for highly efficient oxidative desulfurization","volume":"298","author":"Wang","year":"2021","journal-title":"Appl. Catal. B Environ. Energy"},{"key":"10.1016\/j.aca.2026.346075_bib37","article-title":"V-MOF@carbon nanotube derived three-dimensional V2O5@carbon nanotube as high-performance cathode for aqueous zinc-ion batteries","volume":"942","author":"Liu","year":"2023","journal-title":"J. Electroanal. Chem."},{"key":"10.1016\/j.aca.2026.346075_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2021.138358","article-title":"Exploring the synergetic electrochemical performance of cobalt sulfide\/cobalt phosphate composites for supercapattery devices with high-energy and rate capability","volume":"384","author":"Iqbal","year":"2021","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346075_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.153596","article-title":"Highly conductive AuNPs\/Co-MOF nanocomposites synergistic hybridization chain reaction enzyme-free electrochemical aptasensor for ultrasensitive detection of Aflatoxin B1","volume":"495","author":"Yu","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.346075_bib40","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.6023\/A21050223","article-title":"Metal-organic frameworks (MOF)-based novel electrochemiluminescence biosensing platform for quantification of H2O2 releasing from tumor cells","volume":"79","author":"Liao","year":"2021","journal-title":"Acta Chim. Sinica"},{"key":"10.1016\/j.aca.2026.346075_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.materresbull.2025.113769","article-title":"Morphology-activity relationship study of CoMoO4 for electrocatalytic water oxidation in neutral medium","volume":"194","author":"Yu","year":"2026","journal-title":"Mater. Res. Bull."},{"key":"10.1016\/j.aca.2026.346075_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.138589","article-title":"Defect engineering enhanced coreactant-free electrochemiluminescence of metal-organic frameworks for perfluorooctanoic acid analysis","volume":"445","author":"Zhao","year":"2025","journal-title":"Sensor. Actuat. B-Chem."},{"key":"10.1016\/j.aca.2026.346075_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2026.172679","article-title":"Synthesis, characterization, and ethanol vapor sensing characteristics of vanadium-based-MOFs with and without Cu doping","volume":"529","author":"Doan","year":"2026","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.346075_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2019.135334","article-title":"Supercapacitive performance of CoMoO4 with oxygen vacancy porous nanosheet","volume":"330","author":"Li","year":"2020","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346075_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioelechem.2026.109249","article-title":"Synergistic effect of Co-MoS2 and Au-rGO nanomaterials: Layer-by-layer electrochemical immunosensor realizes high selective trace detection of A\u03b2 oligomers","volume":"170","author":"Cai","year":"2026","journal-title":"Bioelectrochemistry"}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026010251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003267026010251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T08:21:50Z","timestamp":1789806110000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003267026010251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":45,"alternative-id":["S0003267026010251"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2026.346075","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-performance AIECL immunosensor based on V-TCPE metal-organic frameworks and CoMoO4@Au nanoflowers as co-reaction accelerator for ultrasensitive detection of T-2 toxin","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2026.346075","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"346075"}}