{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:09:06Z","timestamp":1789808946257,"version":"4.0.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100022851","name":"Instituto Nacional de Ci\u00eancia e Tecnologia de Bioanal\u00edtica","doi-asserted-by":"publisher","award":["408338\/2024-5"],"award-info":[{"award-number":["408338\/2024-5"]}],"id":[{"id":"10.13039\/501100022851","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2023\/12589-0"],"award-info":[{"award-number":["2023\/12589-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2023 \/00246-1"],"award-info":[{"award-number":["2023 \/00246-1"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2022\/03250-7"],"award-info":[{"award-number":["2022\/03250-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["405620\/2021-7"],"award-info":[{"award-number":["405620\/2021-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["406309 \/2025-6"],"award-info":[{"award-number":["406309 \/2025-6"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["308136\/2025-0"],"award-info":[{"award-number":["308136\/2025-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["310282\/2022-5"],"award-info":[{"award-number":["310282\/2022-5"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["442598\/2023-8"],"award-info":[{"award-number":["442598\/2023-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Analytica Chimica Acta"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.aca.2026.346091","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T23:30:20Z","timestamp":1786059020000},"page":"346091","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Portable 3D-printed system for on-site MDMA electrochemical detection"],"prefix":"10.1016","volume":"1422","author":[{"given":"Elisa D.","family":"Bottelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6083-3184","authenticated-orcid":false,"given":"Larissa M.A.","family":"Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7932-3589","authenticated-orcid":false,"given":"Maxwell D.","family":"Bridges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Boes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3212-0571","authenticated-orcid":false,"given":"Thaisa A.","family":"Baldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9734-7251","authenticated-orcid":false,"given":"Lucas F.","family":"de Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4009-2291","authenticated-orcid":false,"given":"Wendell K.T.","family":"Coltro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1705-1974","authenticated-orcid":false,"given":"Luciano C.","family":"Arantes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5846-4236","authenticated-orcid":false,"given":"William R.","family":"de Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8671-7728","authenticated-orcid":false,"given":"Charles S.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.aca.2026.346091_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2021.113894","article-title":"Neurotoxicity of MDMA: main effects and mechanisms","volume":"347","author":"Costa","year":"2022","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.aca.2026.346091_bib3","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1038\/s41386-019-0569-3","article-title":"Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects","volume":"45","author":"Holze","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.aca.2026.346091_bib5","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1373\/clinchem.2006.069054","article-title":"Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine","volume":"52","author":"Pirnay","year":"2006","journal-title":"Clin. Chem."},{"key":"10.1016\/j.aca.2026.346091_bib6","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jchromb.2007.02.017","article-title":"Development and validation of a disk solid phase extraction and gas chromatography-mass spectrometry method for MDMA, MDA, HMMA, HMA, MDEA, methamphetamine and amphetamine in sweat","volume":"852","author":"De Martinis","year":"2007","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.aca.2026.346091_bib7","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.forsciint.2004.12.041","article-title":"Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection","volume":"150","author":"Concheiro","year":"2005","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.aca.2026.346091_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2018.06.014","article-title":"Portable analytical platforms for forensic chemistry: a review","volume":"1034","author":"de Araujo","year":"2018","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib9","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00604-022-05566-1","article-title":"Laser-scribed graphene on polyetherimide substrate: an electrochemical sensor platform for forensic determination of xylazine in urine and beverage samples","volume":"189","author":"de Lima","year":"2022","journal-title":"Mikrochim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/admi.202101502","article-title":"Laser-induced graphene on paper toward efficient fabrication of flexible, planar electrodes for electrochemical sensing","volume":"8","author":"Pinheiro","year":"2021","journal-title":"Adv. Mater. Interfac."},{"key":"10.1016\/j.aca.2026.346091_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2024.145162","article-title":"Laser\u2010scribed graphene toward scalable fabrication of electrochemical paper-based devices for lidocaine detection in forensic and pharmaceutical samples","volume":"507","author":"Bottelli","year":"2024","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib12","doi-asserted-by":"crossref","first-page":"10432","DOI":"10.3390\/s140610432","article-title":"Disposable screen printed electrochemical sensors: tools for environmental monitoring","volume":"14","author":"Hayat","year":"2014","journal-title":"Sensors (Basel)"},{"key":"10.1016\/j.aca.2026.346091_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2024.144525","article-title":"Automated enzyme-linked immunosorbent assay for point-of-care COVID-19 testing","volume":"497","author":"Baldo","year":"2024","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.124980","article-title":"A do-it-yourself electrochemical cell based on pencil leads and transparency sheets: application to the enzymatic determination of histamine","volume":"266","author":"Torre","year":"2024","journal-title":"Talanta"},{"key":"10.1016\/j.aca.2026.346091_bib15","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/elan.202060080","article-title":"MDMA electrochemical determination and behavior at carbon screen-printed electrodes: cheap tools for forensic applications","volume":"33","author":"Murilo Alves","year":"2021","journal-title":"Electroanal"},{"key":"10.1016\/j.aca.2026.346091_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2020.105088","article-title":"Electrochemical detection of 3,4-methylenedioxymethamphetamine (ecstasy) using a boron-doped diamond electrode with differential pulse voltammetry: simple and fast screening method for application in forensic analysis","volume":"157","author":"Te\u00f3filo","year":"2020","journal-title":"Microchem. J."},{"key":"10.1016\/j.aca.2026.346091_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.ab.2024.115478","article-title":"A simple polyarginine membrane electrochemical sensor for the determination of MDMA and MDA","volume":"688","author":"Duan","year":"2024","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.aca.2026.346091_bib18","doi-asserted-by":"crossref","first-page":"3404","DOI":"10.1002\/celc.202000601","article-title":"Accounts in 3D-Printed electrochemical sensors: towards monitoring of environmental pollutants","volume":"7","author":"Mu\u00f1oz","year":"2020","journal-title":"Chemelectrochem"},{"key":"10.1016\/j.aca.2026.346091_bib19","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.aca.2020.03.028","article-title":"Additive-manufactured (3D-printed) electrochemical sensors: a critical review","volume":"1118","author":"Cardoso","year":"2020","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib20","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1146\/annurev-anchem-091120-093659","article-title":"3D printed electrochemical sensors","volume":"14","author":"Abdalla","year":"2021","journal-title":"Annu. Rev. Anal. Chem."},{"key":"10.1016\/j.aca.2026.346091_bib21","doi-asserted-by":"crossref","first-page":"5753","DOI":"10.1021\/acs.analchem.8b00083","article-title":"3D-Printed graphene\/polylactic acid electrodes promise high sensitivity in electroanalysis","volume":"90","author":"Manzanares Palenzuela","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.aca.2026.346091_bib22","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.elecom.2019.04.004","article-title":"The capacitance and electron transfer of 3D-printed graphene electrodes are dramatically influenced by the type of solvent used for pre-treatment","volume":"102","author":"Gusm\u00e3o","year":"2019","journal-title":"Electrochem. Commun."},{"key":"10.1016\/j.aca.2026.346091_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2020.135688","article-title":"Improved electrochemical detection of metals in biological samples using 3D-printed electrode: chemical\/electrochemical treatment exposes carbon-black conductive sites","volume":"335","author":"Rocha","year":"2020","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2022.141002","article-title":"Cyclic square-wave voltammetric discrimination of the amphetamine-type stimulants MDA and MDMA in real-world forensic samples by 3D-printed carbon electrodes","volume":"429","author":"de Faria","year":"2022","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.130594","article-title":"Reagentless and sub-minute laser-scribing treatment to produce enhanced disposable electrochemical sensors via additive manufacture","volume":"425","author":"Rocha","year":"2021","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.aca.2026.346091_bib26","unstructured":"Table of Characteristic IR Absorptions. (accessed June 20, 2026)."},{"key":"10.1016\/j.aca.2026.346091_bib27","series-title":"Electrochemical Methods: Fundamentals and Applications","author":"Bard","year":"2001"},{"key":"10.1016\/j.aca.2026.346091_bib28","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.bioelechem.2009.12.002","article-title":"Electrochemical oxidation of amphetamine-like drugs and application to electroanalysis of ecstasy in human serum","volume":"79","author":"Garrido","year":"2010","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.aca.2026.346091_bib29","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1021\/cr068065t","article-title":"Electrochemical approach to the mechanistic study of proton-coupled electron transfer","volume":"108","author":"Costentin","year":"2008","journal-title":"Chem. Rev."},{"key":"10.1016\/j.aca.2026.346091_bib30","doi-asserted-by":"crossref","first-page":"10386","DOI":"10.1021\/la100134r","article-title":"Development and characterization of a voltammetric carbon-fiber microelectrode pH sensor","volume":"26","author":"Makos","year":"2010","journal-title":"Langmuir"},{"key":"10.1016\/j.aca.2026.346091_bib31","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1351\/pac199769020297","article-title":"A statistical overview of standard (IUPAC and ACS) and new procedures for determining the limits of detection and quantification: application to voltammetric and stripping techniques (Technical report)","volume":"69","author":"Mocak","year":"1997","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.aca.2026.346091_bib32","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1016\/j.chemosphere.2011.05.033","article-title":"Evaluation of the presence of drugs of abuse in tap waters","volume":"84","author":"Rosa Boleda","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.aca.2026.346091_bib33","doi-asserted-by":"crossref","first-page":"3291","DOI":"10.1039\/D2AN00351A","article-title":"Polydopamine-based molecularly imprinted electrochemical sensor for the highly selective determination of ecstasy components","volume":"147","author":"Li","year":"2022","journal-title":"Analyst"},{"key":"10.1016\/j.aca.2026.346091_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2021.137803","article-title":"Highly sensitive electrochemical sensor based on Pt nanoparticles\/carbon nanohorns for simultaneous determination of morphine and MDMA in biological samples","volume":"370","author":"Zhang","year":"2021","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.electacta.2024.144041","article-title":"Combined colorimetric and electrochemical screening method using 3D printed devices: towards the selective detection of MDMA in forensic samples","volume":"483","author":"Melo","year":"2024","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.aca.2026.346091_bib38","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1046\/j.1360-0443.2002.00222.x","article-title":"The content of ecstasy tablets: implications for the study of their long-term effects","volume":"97","author":"Cole","year":"2002","journal-title":"Addiction"},{"key":"10.1016\/j.aca.2026.346091_bib39","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s11419-024-00691-3","article-title":"Chemical composition of Ecstasy tablets seized in Poland between 2005 and 2020","volume":"43","author":"Byrska","year":"2025","journal-title":"Forensic Toxicol."},{"key":"10.1016\/j.aca.2026.346091_bib40","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/dar.13412","article-title":"A quantitative analysis of MDMA seized at New South Wales music festivals over the 2019\/2020 season: form, purity, dose and adulterants","volume":"41","author":"O'Reilly","year":"2022","journal-title":"Drug Alcohol Rev."},{"key":"10.1016\/j.aca.2026.346091_bib41","first-page":"108","article-title":"Evaluation of immunoassays for the determination of MDMA and cannabinoids in urine samples","volume":"11","author":"Lua","year":"2003","journal-title":"J. Food Drug Anal."},{"key":"10.1016\/j.aca.2026.346091_bib42","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/FTD.0b013e3181684fa0","article-title":"Plasma pharmacokinetics of 3,4-methylenedioxymethamphetamine after controlled oral administration to young adults","volume":"30","author":"Kolbrich","year":"2008","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.aca.2026.346091_bib43","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/jat\/33.8.439","article-title":"Urinary MDMA, MDA, HMMA, and HMA excretion following controlled MDMA administration to humans","volume":"33","author":"Abraham","year":"2009","journal-title":"J. Anal. Toxicol."}],"container-title":["Analytica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000326702601041X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000326702601041X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T08:20:16Z","timestamp":1789806016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000326702601041X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":39,"alternative-id":["S000326702601041X"],"URL":"https:\/\/doi.org\/10.1016\/j.aca.2026.346091","relation":{},"ISSN":["0003-2670"],"issn-type":[{"value":"0003-2670","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Portable 3D-printed system for on-site MDMA electrochemical detection","name":"articletitle","label":"Article Title"},{"value":"Analytica Chimica Acta","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.aca.2026.346091","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"346091"}}