{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T01:51:53Z","timestamp":1762480313173,"version":"build-2065373602"},"reference-count":6,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001505","name":"Health Research Council of New Zealand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001505","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Critical Care &amp; Pain Medicine"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.accpm.2021.100858","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T19:47:54Z","timestamp":1617133674000},"page":"100858","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Is less really more for oxygen therapy in patients with acute respiratory failure?"],"prefix":"10.1016","volume":"40","author":[{"given":"Paul J.","family":"Young","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Gladwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Capdevila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.accpm.2021.100858_bib0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1164\/rccm.201505-1019OC","article-title":"Conservative versus liberal oxygenation targets for mechanically ventilated patients. A pilot multicenter randomized controlled trial","volume":"193","author":"Panwar","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.accpm.2021.100858_bib0010","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1001\/jama.2016.11993","article-title":"Effect of conservative vs conventional oxygen therapy on mortality among patients in an intensive care unit: the oxygen-ICU randomized clinical trial","volume":"316","author":"Girardis","year":"2016","journal-title":"JAMA"},{"issue":"March (11)","key":"10.1016\/j.accpm.2021.100858_bib0015","first-page":"989","article-title":"Conservative oxygen therapy during mechanical ventilation in the ICU","volume":"382","author":"ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.accpm.2021.100858_bib0020","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1056\/NEJMoa1916431","article-title":"Liberal or conservative oxygen therapy for acute respiratory distress syndrome","volume":"382","author":"Barrot","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.accpm.2021.100858_bib0025","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJMoa2032510","article-title":"Lower or higher oxygenation targets for acute hypoxemic respiratory failure","volume":"384","author":"Schjorring","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.accpm.2021.100858_bib0030","first-page":"230","article-title":"O2, do we know what to do?","volume":"21","author":"Young","year":"2019","journal-title":"Crit Care Resusc"}],"container-title":["Anaesthesia Critical Care &amp; Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352556821000618?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352556821000618?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T01:48:06Z","timestamp":1762480086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352556821000618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S2352556821000618"],"URL":"https:\/\/doi.org\/10.1016\/j.accpm.2021.100858","relation":{},"ISSN":["2352-5568"],"issn-type":[{"type":"print","value":"2352-5568"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is less really more for oxygen therapy in patients with acute respiratory failure?","name":"articletitle","label":"Article Title"},{"value":"Anaesthesia Critical Care & Pain Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.accpm.2021.100858","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Soci\u00e9t\u00e9 fran\u00e7aise d'anesth\u00e9sie et de r\u00e9animation (Sfar). Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100858"}}