{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T19:08:36Z","timestamp":1792868916379,"version":"4.5.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["2009322"],"award-info":[{"award-number":["2009322"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020265","name":"Stan Perron Charitable Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001797","name":"Curtin University of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001797","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011302","name":"Children&apos;s Hospital Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011302","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022938","name":"Children\u2019s Hospital Foundation","doi-asserted-by":"publisher","award":["9522"],"award-info":[{"award-number":["9522"]}],"id":[{"id":"10.13039\/501100022938","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Critical Care &amp; Pain Medicine"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.accpm.2024.101455","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T17:55:00Z","timestamp":1734630900000},"page":"101455","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Jet versus vibrating mesh nebulizer for tobramycin aerosol in spontaneously breathing children with tracheostomies: A simulation study"],"prefix":"10.1016","volume":"44","author":[{"given":"Natalie V.E.","family":"Anderson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3096-7584","authenticated-orcid":false,"given":"William G.F.","family":"Ditcham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry S.","family":"Clements","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8043-8541","authenticated-orcid":false,"given":"Britta S.","family":"von Ungern-Sternberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.accpm.2024.101455_bib0005","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1111\/resp.14121","article-title":"Ventilatory support at home for children: a joint position paper from the Thoracic Society of Australia and New Zealand\/Australasian Sleep Association","volume":"26","author":"Chawla","year":"2021","journal-title":"Respirology"},{"issue":"1","key":"10.1016\/j.accpm.2024.101455_bib0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/0194599819887096","article-title":"Epidemiology of pediatric tracheostomy and risk factors for poor outcomes: an 11-year single-center experience","volume":"162","author":"Chia","year":"2020","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"2","key":"10.1016\/j.accpm.2024.101455_bib0015","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jped.2021.07.004","article-title":"Tracheostomy practices in children on mechanical ventilation: a systematic review and meta-analysis","volume":"98","author":"de Araujo","year":"2022","journal-title":"J Pediatr (Rio J)"},{"issue":"6","key":"10.1016\/j.accpm.2024.101455_bib0020","doi-asserted-by":"crossref","first-page":"799","DOI":"10.4187\/respcare.05366","article-title":"Tracheostomy in infants and children","volume":"62","author":"Watters","year":"2017","journal-title":"Respir Care"},{"issue":"5","key":"10.1016\/j.accpm.2024.101455_bib0025","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1002\/ppul.25873","article-title":"Diagnosis, management, and outcomes of pediatric tracheostomy-associated infections: a scoping review","volume":"57","author":"Morrison","year":"2022","journal-title":"Pediatr Pulmonol"},{"issue":"1","key":"10.1016\/j.accpm.2024.101455_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3904\/kjim.2021.277","article-title":"Aerosolized antibiotics in the treatment of hospital-acquired pneumonia\/ventilator-associated pneumonia","volume":"37","author":"Jung","year":"2022","journal-title":"Korean J Intern Med"},{"key":"10.1016\/j.accpm.2024.101455_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2021.106728","article-title":"Bronchiectasis and inhaled tobramycin: a literature review","volume":"192","author":"Elborn","year":"2022","journal-title":"Respir Med"},{"issue":"8","key":"10.1016\/j.accpm.2024.101455_bib0040","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.4187\/respcare.01518","article-title":"Survey of aerosol delivery techniques to spontaneously breathing tracheostomized children","volume":"57","author":"Willis","year":"2012","journal-title":"Respir Care"},{"issue":"1","key":"10.1016\/j.accpm.2024.101455_bib0045","doi-asserted-by":"crossref","first-page":"144","DOI":"10.4187\/respcare.08137","article-title":"AARC Clinical Practice Guideline: management of pediatric patients with tracheostomy in the acute care setting","volume":"66","author":"Teresa","year":"2021","journal-title":"Respir Care"},{"key":"10.1016\/j.accpm.2024.101455_bib0050","series-title":"Cystic fibrosis: antibiotic therapy for chronic pulmonary infection. UpToDate","author":"Simon","year":"2023"},{"key":"10.1016\/j.accpm.2024.101455_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijporl.2021.110665","article-title":"The effect of nebulized antibiotics in children with tracheostomy","volume":"143","author":"Atag","year":"2021","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"3","key":"10.1016\/j.accpm.2024.101455_bib0060","doi-asserted-by":"crossref","first-page":"00149","DOI":"10.1183\/23120541.00149-2018","article-title":"Reducing the frequency of respiratory tract infections in severe neurological disorders by inhaled antibiotics: a retrospective data analysis","volume":"5","author":"Eckerland","year":"2019","journal-title":"ERJ Open Res"},{"key":"10.1016\/j.accpm.2024.101455_bib0065","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.pupt.2018.04.006","article-title":"Characterisation of 40 mg\/ml and 100 mg\/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation","volume":"50","author":"Dhanani","year":"2018","journal-title":"Pulm Pharmacol Ther"},{"issue":"11","key":"10.1016\/j.accpm.2024.101455_bib0070","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1016\/j.rmed.2009.04.029","article-title":"Aerosol delivery of nebulised budesonide in young children with asthma","volume":"103","author":"Schueepp","year":"2009","journal-title":"Respir Med"},{"issue":"1","key":"10.1016\/j.accpm.2024.101455_bib0075","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/s13054-016-1448-5","article-title":"Fundamentals of aerosol therapy in critical care","volume":"20","author":"Dhanani","year":"2016","journal-title":"Crit Care"},{"issue":"8","key":"10.1016\/j.accpm.2024.101455_bib0080","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1016\/j.xphs.2017.04.062","article-title":"Aerosol production by vibrating membrane technology: analysis of the electrolyte effect on generated droplet size and nebulizer output rate","volume":"106","author":"Beck-Broichsitter","year":"2017","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.accpm.2024.101455_bib0085","series-title":"ISO 27427:2023 Anaesthetic and respiratory equipment - nebulizing systems and components","year":"2023"},{"issue":"12","key":"10.1016\/j.accpm.2024.101455_bib0090","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1111\/pan.14028","article-title":"Assessment of different techniques for the administration of inhaled salbutamol in children breathing spontaneously via tracheal tubes, supraglottic airway devices, and tracheostomies","volume":"30","author":"Anderson","year":"2020","journal-title":"Paediatr Anaesth"},{"issue":"2","key":"10.1016\/j.accpm.2024.101455_bib0095","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/pan.14354","article-title":"Aerosolized drug delivery in awake and anesthetized children to treat bronchospasm","volume":"32","author":"Anderson","year":"2022","journal-title":"Paediatr Anaesth"},{"issue":"11","key":"10.1016\/j.accpm.2024.101455_bib0100","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.4187\/respcare.06022","article-title":"Effects of fill volume and humidification on aerosol delivery during single-limb noninvasive ventilation","volume":"63","author":"Saeed","year":"2018","journal-title":"Respir Care"}],"container-title":["Anaesthesia Critical Care &amp; Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352556824001139?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352556824001139?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T13:28:02Z","timestamp":1740749282000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352556824001139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S2352556824001139"],"URL":"https:\/\/doi.org\/10.1016\/j.accpm.2024.101455","relation":{},"ISSN":["2352-5568"],"issn-type":[{"value":"2352-5568","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Jet versus vibrating mesh nebulizer for tobramycin aerosol in spontaneously breathing children with tracheostomies: A simulation study","name":"articletitle","label":"Article Title"},{"value":"Anaesthesia Critical Care & Pain Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.accpm.2024.101455","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Masson SAS on behalf of Soci\u00e9t\u00e9 Fran\u00e7aise d'Anesth\u00e9sie et de R\u00e9animation (SFAR).","name":"copyright","label":"Copyright"}],"article-number":"101455"}}