{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:41:56Z","timestamp":1792424516715,"version":"4.5.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia Critical Care &amp; Pain Medicine"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.accpm.2026.101911","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:52:49Z","timestamp":1790232769000},"page":"101911","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Caustic ingestion in adult patients, what you should know, what is debated and what should come next"],"prefix":"10.1016","volume":"46","author":[{"given":"Tha\u00efs","family":"Walter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mircea","family":"Chirica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Lartigau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Denis","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Bonavina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Gosselin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Deniau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Depret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.accpm.2026.101911_bib0005","doi-asserted-by":"crossref","first-page":"doaa012","DOI":"10.1093\/dote\/doaa012","article-title":"Nationwide estimate of emergency department visits in the United States related to caustic ingestion","volume":"33","author":"Li","year":"2020","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.accpm.2026.101911_bib0010","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.anrea.2023.10.003","article-title":"Activit\u00e9 des r\u00e9animations fran\u00e7aises \u00e0 partir d\u2019une base de donn\u00e9es nationale entre 2013 et 2019 : une gravit\u00e9 en augmentation, mais des dur\u00e9es de s\u00e9jour et un taux de mortalit\u00e9 en baisse","volume":"9","author":"Boulet","year":"2023","journal-title":"Anesth R\u00e9anim"},{"key":"10.1016\/j.accpm.2026.101911_bib0015","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00068-023-02392-9","article-title":"Epidemiologic features and outcomes associated with caustic ingestion among adults admitted in intensive care unit from 2013 to 2019: a French national observational study","volume":"50","author":"Deniau","year":"2024","journal-title":"Eur J Trauma Emerg Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0020","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1001\/jamasurg.2021.6368","article-title":"Outcomes associated with caustic ingestion among adults in a national prospective database in France","volume":"157","author":"Challine","year":"2022","journal-title":"JAMA Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0025","first-page":"e56","article-title":"Epidemiologic features and outcomes of caustic ingestions; a 10-year cross-sectional study","volume":"5","author":"Alipour Faz","year":"2017","journal-title":"Emerg (Tehran)"},{"key":"10.1016\/j.accpm.2026.101911_bib0030","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1177\/10398562251353370","article-title":"Pattern of emergency department presentations for deliberate self-harm at a tertiary care hospital in Pakistan: a cross-sectional study","volume":"33","author":"Imran","year":"2025","journal-title":"Australas Psychiatry"},{"key":"10.1016\/j.accpm.2026.101911_bib0035","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.2147\/RMHP.S272527","article-title":"The association between caustic ingestion and psychiatric comorbidity based on 396 adults within 20 years","volume":"13","author":"Chen","year":"2020","journal-title":"RMHP"},{"key":"10.1016\/j.accpm.2026.101911_bib0040","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4274\/tjtcs.2025.28277","article-title":"Evolving diagnostic and therapeutic methods in corrosive esophagitis: evaluation of a diagnostic and therapeutic algorithm based on 26 years of experience","volume":"34","author":"Pirzirenli","year":"2026","journal-title":"Tjtcs"},{"key":"10.1016\/j.accpm.2026.101911_bib0045","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1177\/0960327111412803","article-title":"Evaluation of caustics and household detergents exposures in an emergency service","volume":"31","author":"Ar\u0131c\u0131","year":"2012","journal-title":"Hum Exp Toxicol"},{"key":"10.1016\/j.accpm.2026.101911_bib0050","doi-asserted-by":"crossref","first-page":"e529","DOI":"10.1097\/SLA.0000000000003774","article-title":"Quality of life after caustic ingestion","volume":"274","author":"Faron","year":"2021","journal-title":"Ann Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0055","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1007\/s00464-014-3823-0","article-title":"Computed tomography evaluation of high-grade esophageal necrosis after corrosive ingestion to avoid unnecessary esophagectomy","volume":"29","author":"Chirica","year":"2015","journal-title":"Surg Endosc"},{"key":"10.1016\/j.accpm.2026.101911_bib0060","doi-asserted-by":"crossref","first-page":"doac032","DOI":"10.1093\/dote\/doac032","article-title":"Emergency computed tomography evaluation of caustic ingestion","volume":"35","author":"Assalino","year":"2022","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.accpm.2026.101911_bib0065","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.bja.2024.07.032","article-title":"Hydrochloric acid ingestion in adults: presentation and outcomes in a 10-year retrospective cohort study","volume":"133","author":"Sabz\u00e9","year":"2024","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.accpm.2026.101911_bib0070","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/01.JAA.0000000000000272","article-title":"Ingestion of sulfuric (battery) acid","volume":"39","author":"Letizia","year":"2026","journal-title":"JAAPA"},{"key":"10.1016\/j.accpm.2026.101911_bib0075","article-title":"Sulfuric acid ingestion: may the severity of the metabolic acidosis be considered as a predictive sign of late damage to the gastrointestinal tract?","volume":"11","author":"Mastrodicasa","year":"2024","journal-title":"Eur J Case Rep Intern Med"},{"key":"10.1016\/j.accpm.2026.101911_bib0080","doi-asserted-by":"crossref","DOI":"10.14309\/crj.0000000000001882","article-title":"Bubble trouble: portal venous gas embolism following hydrogen peroxide enema","volume":"12","author":"Mann","year":"2025","journal-title":"ACG Case Rep J"},{"key":"10.1016\/j.accpm.2026.101911_bib0085","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1177\/229255031402200202","article-title":"A review of hydrofluoric acid burn management","volume":"22","author":"Mckee","year":"2014","journal-title":"Plast Surg (Oakv)"},{"key":"10.1016\/j.accpm.2026.101911_bib0090","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.jemermed.2025.09.033","article-title":"Hydrofluoric acid fatality from dermal exposure","volume":"79","author":"Ramesh","year":"2025","journal-title":"J Emerg Med"},{"key":"10.1016\/j.accpm.2026.101911_bib0095","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/10408440701669959","article-title":"Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment","volume":"38","author":"Dinis-Oliveira","year":"2008","journal-title":"Crit Rev Toxicol"},{"key":"10.1016\/j.accpm.2026.101911_bib0100","doi-asserted-by":"crossref","first-page":"4717","DOI":"10.1016\/j.radcr.2022.08.088","article-title":"White spirit poisoning: an unusual cause of hepatic portal venous gas","volume":"17","author":"Symeonidis","year":"2022","journal-title":"Radiol Case Rep"},{"key":"10.1016\/j.accpm.2026.101911_bib0105","doi-asserted-by":"crossref","first-page":"236","DOI":"10.3109\/15563650.2014.887726","article-title":"Peri-anal injury following ingestion of White Spirit","volume":"52","author":"Cassidy","year":"2014","journal-title":"Clin Toxicol"},{"key":"10.1016\/j.accpm.2026.101911_bib0110","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1177\/1559827611410265","article-title":"Intimate partner violence and adverse health consequences: implications for clinicians","volume":"5","author":"Black","year":"2011","journal-title":"Am J Lifestyle Med"},{"key":"10.1016\/j.accpm.2026.101911_bib0115","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1471-2296-8-49","article-title":"The sensitivity and specificity of four questions (HARK) to identify intimate partner violence: a diagnostic accuracy study in general practice","volume":"8","author":"Sohal","year":"2007","journal-title":"BMC Fam Pract"},{"key":"10.1016\/j.accpm.2026.101911_bib0120","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1007\/s11606-013-2534-x","article-title":"Clinical utility of an intimate partner violence screening tool for female VHA patients","volume":"28","author":"Iverson","year":"2013","journal-title":"J Gen Intern Med"},{"key":"10.1016\/j.accpm.2026.101911_bib0125","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.whi.2008.08.003","article-title":"Who is identified by screening for intimate partner violence?","volume":"18","author":"Wathen","year":"2008","journal-title":"Womens Health Issues"},{"key":"10.1016\/j.accpm.2026.101911_bib0130","unstructured":"WHO Team for Sexual and Reproductive Health and Research (SRH). Caring for women subjected to violence: a WHO curriculum for training health-care providers. World Health Organization; n.d."},{"key":"10.1016\/j.accpm.2026.101911_bib0135","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.anrea.2017.09.003","article-title":"Intubation difficile et extubation en anesth\u00e9sie chez l\u2019adulte","volume":"3","author":"Langeron","year":"2017","journal-title":"Anesth R\u00e9anim"},{"key":"10.1016\/j.accpm.2026.101911_bib0140","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13049-016-0240-5","article-title":"Acute emergency care and airway management of caustic ingestion in adults: single center observational study","volume":"24","author":"Struck","year":"2016","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"10.1016\/j.accpm.2026.101911_bib0145","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s13017-019-0245-2","article-title":"Esophageal emergencies: WSES guidelines","volume":"14","author":"Chirica","year":"2019","journal-title":"World J Emerg Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0150","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0140-6736(16)30313-0","article-title":"Caustic ingestion","volume":"389","author":"Chirica","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.accpm.2026.101911_bib0155","series-title":"[Prise en charge en urgence des ingestions de caustique]. EMC - Gastro-ent\u00e9rologie","author":"Chirica","year":"2025"},{"key":"10.1016\/j.accpm.2026.101911_bib0160","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1097\/SLA.0b013e3180cc2eaa","article-title":"Colopharyngoplasty for the treatment of severe pharyngoesophageal caustic injuries: an audit of 58 patients","volume":"246","author":"Chirica","year":"2007","journal-title":"Ann Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0165","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1097\/SLA.0000000000001188","article-title":"Tracheobronchial necrosis after caustic ingestion","volume":"263","author":"Benjamin","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0170","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1001\/jamapsychiatry.2014.3188","article-title":"Risk of suicide following deliberate self-poisoning","volume":"72","author":"Finkelstein","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.accpm.2026.101911_bib0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.surg.2025.109658","article-title":"Corrosive ingestion-induced esophageal injuries: a systematic review and meta-analysis","volume":"187","author":"Papaconstantinou","year":"2025","journal-title":"Surgery"},{"key":"10.1016\/j.accpm.2026.101911_bib0180","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/SLA.0000000000002732","article-title":"Emergency computed tomography predicts caustic esophageal stricture formation","volume":"270","author":"Bruzzi","year":"2019","journal-title":"Ann Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0185","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0022-3476(85)80119-0","article-title":"Caustic substance injuries","volume":"107","author":"Wasserman","year":"1985","journal-title":"J Pediatr"},{"key":"10.1016\/j.accpm.2026.101911_bib0190","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1002\/1097-0142(19800515)45:10<2655::AID-CNCR2820451028>3.0.CO;2-P","article-title":"Lye corrosion carcinoma of the esophagus. A review of 63 cases","volume":"45","author":"Appelqvist","year":"1980","journal-title":"Cancer"},{"key":"10.1016\/j.accpm.2026.101911_bib0195","doi-asserted-by":"crossref","first-page":"4513","DOI":"10.1007\/s00464-025-11820-3","article-title":"Endoscopic and surgical treatment of refractory caustic esophageal strictures","volume":"39","author":"Chobarporn","year":"2025","journal-title":"Surg Endosc"},{"key":"10.1016\/j.accpm.2026.101911_bib0200","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/SLA.0000000000001459","article-title":"Computed tomography evaluation of esophagogastric necrosis after caustic ingestion","volume":"264","author":"Chirica","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0205","doi-asserted-by":"crossref","first-page":"e1518","DOI":"10.1542\/peds.2013-3331","article-title":"High doses of methylprednisolone in the management of caustic esophageal burns","volume":"133","author":"Usta","year":"2014","journal-title":"Pediatrics"},{"key":"10.1016\/j.accpm.2026.101911_bib0210","series-title":"A controlled trial of corticosteriods in children with corrosive injury of the esophagus","first-page":"637","author":"Anderson","year":"1990"},{"key":"10.1016\/j.accpm.2026.101911_bib0215","doi-asserted-by":"crossref","first-page":"20","DOI":"10.4103\/tjem.tjem_134_23","article-title":"Role of high-dose methylprednisolone in Zargar Grade IIB corrosive esophageal burns: a randomized control study","volume":"24","author":"Sheikh","year":"2024","journal-title":"Turk J Emerg Med"},{"key":"10.1016\/j.accpm.2026.101911_bib0220","doi-asserted-by":"crossref","first-page":"tfad125","DOI":"10.1093\/toxres\/tfad125","article-title":"Role of N-acetylcysteine and vitamin B complex in improving outcomes of corrosive ingestion","volume":"13","author":"El-Sobky","year":"2024","journal-title":"Toxicol Res"},{"key":"10.1016\/j.accpm.2026.101911_bib0225","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1007\/s00464-020-07707-0","article-title":"A prospective randomized controlled trial of omeprazole for preventing esophageal stricture in grade 2b and 3a corrosive esophageal injuries","volume":"35","author":"Mahawongkajit","year":"2021","journal-title":"Surg Endosc"},{"key":"10.1016\/j.accpm.2026.101911_bib0230","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/jpc.16595","article-title":"Early topical mitomycin-prevents stricture formation in children with caustic ingestion","volume":"60","author":"Sawires","year":"2024","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.accpm.2026.101911_bib0235","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.jpedsurg.2013.04.014","article-title":"Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebo-controlled trial","volume":"48","author":"El-Asmar","year":"2013","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0240","doi-asserted-by":"crossref","first-page":"4932","DOI":"10.1007\/s00464-018-6253-6","article-title":"Prospective study of the effect of topical application of Mitomycin C in refractory pediatric caustic esophageal strictures","volume":"32","author":"Ghobrial","year":"2018","journal-title":"Surg Endosc"},{"key":"10.1016\/j.accpm.2026.101911_bib0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpedsurg.2025.162884","article-title":"Topical mitomycin C application versus intralesional corticosteroid injection in the management of caustic esophageal strictures in pediatrics: a randomized controlled trial","volume":"61","author":"Zaki","year":"2026","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.accpm.2026.101911_bib0250","doi-asserted-by":"crossref","first-page":"e122","DOI":"10.1097\/SLE.0000000000000351","article-title":"The efficacy of intralesional steroid injection in the treatment of corrosive esophageal strictures in children","volume":"26","author":"Divarci","year":"2016","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"10.1016\/j.accpm.2026.101911_bib0255","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.1007\/s00464-022-09767-w","article-title":"SX-ELLA biodegradable stent for benign oesophageal strictures: a systematic review and proportion meta-analysis","volume":"37","author":"Kailla","year":"2023","journal-title":"Surg Endosc"},{"key":"10.1016\/j.accpm.2026.101911_bib0260","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.actbio.2022.04.038","article-title":"Biodegradable PTX-PLGA-coated magnesium stent for benign esophageal stricture: an experimental study","volume":"146","author":"Liu","year":"2022","journal-title":"Acta Biomaterialia"},{"key":"10.1016\/j.accpm.2026.101911_bib0265","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.gie.2008.04.022","article-title":"An extracellular matrix scaffold for esophageal stricture prevention after circumferential EMR","volume":"69","author":"Nieponice","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.accpm.2026.101911_bib0270","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.surg.2021.07.009","article-title":"Circumferential esophageal replacement by a decellularized esophageal matrix in a porcine model","volume":"171","author":"Levenson","year":"2022","journal-title":"Surgery"},{"key":"10.1016\/j.accpm.2026.101911_bib0275","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1177\/0963689717741498","article-title":"Circumferential esophageal replacement by a tissue-engineered substitute using mesenchymal stem cells: an experimental study in mini pigs","volume":"26","author":"Catry","year":"2017","journal-title":"Cell Transplant"}],"container-title":["Anaesthesia Critical Care &amp; Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352556826001694?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352556826001694?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:10:05Z","timestamp":1792422605000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352556826001694"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":55,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2027,1]]}},"alternative-id":["S2352556826001694"],"URL":"https:\/\/doi.org\/10.1016\/j.accpm.2026.101911","relation":{},"ISSN":["2352-5568"],"issn-type":[{"value":"2352-5568","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Caustic ingestion in adult patients, what you should know, what is debated and what should come next","name":"articletitle","label":"Article Title"},{"value":"Anaesthesia Critical Care & Pain Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.accpm.2026.101911","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Masson SAS on behalf of Soci\u00e9t\u00e9 Fran\u00e7aise d'Anesth\u00e9sie et de R\u00e9animation (SFAR).","name":"copyright","label":"Copyright"}],"article-number":"101911"}}