{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T16:56:51Z","timestamp":1761929811384,"version":"3.40.5"},"reference-count":19,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["NS045013","TL1 RR024129-01","5T32EB001631-07"],"award-info":[{"award-number":["NS045013","TL1 RR024129-01","5T32EB001631-07"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.acra.2016.04.004","type":"journal-article","created":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T12:13:14Z","timestamp":1468930394000},"page":"1073-1082","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["The Development of Reduced Diffusion Following Bevacizumab Therapy Identifies Regions of Recurrent Disease in Patients with High-grade Glioma"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5093-4168","authenticated-orcid":false,"suffix":"Jr","given":"Ramon F.","family":"Barajas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas A.","family":"Butowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna J.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish K.","family":"Aghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchel S.","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan M.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soonmee","family":"Cha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.acra.2016.04.004_bib0010","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s11060-009-0098-8","article-title":"Bevacizumab-induced diffusion-restricted lesions in malignant glioma patients","volume":"99","author":"Rieger","year":"2010","journal-title":"J Neurooncol"},{"key":"10.1016\/j.acra.2016.04.004_bib0015","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1200\/JCO.2009.25.0233","article-title":"Diffusion magnetic resonance imaging detects pathologically confirmed, nonenhancing tumor progression in a patient with recurrent glioblastoma receiving bevacizumab","volume":"28","author":"Gerstner","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.acra.2016.04.004_bib0020","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s11060-009-9981-6","article-title":"Imaging response criteria for recurrent gliomas treated with bevacizumab: role of diffusion weighted imaging as an imaging biomarker","volume":"96","author":"Jain","year":"2010","journal-title":"J Neurooncol"},{"key":"10.1016\/j.acra.2016.04.004_bib0025","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1148\/radiol.2521081534","article-title":"Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment","volume":"252","author":"Pope","year":"2009","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.04.004_bib0030","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1148\/radiol.09090663","article-title":"Glioblastoma multiforme regional genetic and cellular expression patterns: influence on anatomic and physiologic MR imaging","volume":"254","author":"Barajas","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.04.004_bib0035","doi-asserted-by":"crossref","first-page":"591","DOI":"10.2214\/ajr.159.3.1503032","article-title":"Diffusion MR imaging: clinical applications","volume":"159","author":"Le Bihan","year":"1992","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.acra.2016.04.004_bib0040","first-page":"343","article-title":"Diffusion MR imaging: theory and applications","volume":"9","author":"Rowley","year":"1999","journal-title":"Neuroimaging Clin N Am"},{"key":"10.1016\/j.acra.2016.04.004_bib0045","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1148\/radiology.161.2.3763909","article-title":"MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders","volume":"161","author":"Le Bihan","year":"1986","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.04.004_bib0050","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1148\/radiol.2241010637","article-title":"Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics","volume":"224","author":"Guo","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.04.004_bib0055","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/jnci\/92.3.205","article-title":"New guidelines to evaluate the response to treatment in solid tumors: European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada","volume":"92","author":"Therasse","year":"2000","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.acra.2016.04.004_bib0060","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1200\/JCO.1990.8.7.1277","article-title":"Response criteria for phase II studies of malignant glioma","volume":"8","author":"Macdonald","year":"1990","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.acra.2016.04.004_bib0065","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1212\/01.wnl.0000304121.57857.38","article-title":"Bevacizumab for recurrent malignant gliomas; efficacy, toxicity, and patterns of recurrence","volume":"70","author":"Norden","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.acra.2016.04.004_bib0070","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1212\/WNL.0b013e3181bc0184","article-title":"Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma","volume":"73","author":"Iwamoto","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.acra.2016.04.004_bib0075","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1186\/1471-2407-9-444","article-title":"Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme","volume":"9","author":"Verhoeff","year":"2009","journal-title":"BMC Cancer"},{"key":"10.1016\/j.acra.2016.04.004_bib0080","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1200\/JCO.2009.26.3541","article-title":"Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group","volume":"28","author":"Wen","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.acra.2016.04.004_bib0085","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.3174\/ajnr.A2479","article-title":"Isolated diffusion restriction precedes the development of enhancing tumor in a subset of patients with glioblastoma","volume":"32","author":"Gupta","year":"2011","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.acra.2016.04.004_bib0090","first-page":"731361","article-title":"Assessing biological response to bevacizumab using 18F-Fluoromisonidazole PET\/MR imaging in a patient with recurrent anaplastic astrocytoma","volume":"2015","author":"Barajas","year":"2015","journal-title":"Case Rep Radiol"},{"key":"10.1016\/j.acra.2016.04.004_bib0095","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s11060-012-0847-y","article-title":"Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study","volume":"108","author":"Pope","year":"2012","journal-title":"J Neurooncol"},{"key":"10.1016\/j.acra.2016.04.004_bib0100","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s11060-011-0638-x","article-title":"Quantification of edema reduction using differential quantitative T2 (DQT2) relaxometry mapping in recurrent glioblastoma treated with bevacizumab","volume":"106","author":"Ellingson","year":"2012","journal-title":"J Neurooncol"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633216300721?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633216300721?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,10]],"date-time":"2018-09-10T07:51:15Z","timestamp":1536565875000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633216300721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S1076633216300721"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2016.04.004","relation":{},"ISSN":["1076-6332"],"issn-type":[{"type":"print","value":"1076-6332"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Development of Reduced Diffusion Following Bevacizumab Therapy Identifies Regions of Recurrent Disease in Patients with High-grade Glioma","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2016.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier Inc. on behalf of The Association of University Radiologists.","name":"copyright","label":"Copyright"}]}}