{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T18:22:15Z","timestamp":1770834135134,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["academicradiology.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.acra.2016.06.002","type":"journal-article","created":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T11:15:43Z","timestamp":1472814943000},"page":"1349-1358","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Texture-based Quantification of Centrilobular Emphysema and Centrilobular Nodularity in Longitudinal CT Scans of Current and Former Smokers"],"prefix":"10.1016","volume":"23","author":[{"given":"Shoshana B.","family":"Ginsburg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Humphries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sungshick","family":"Jou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiro","family":"Yagihashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce D.","family":"Schroeder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.acra.2016.06.002_bib0010","first-page":"1","article-title":"Deaths: preliminary data for 2011","volume":"61","author":"Hoyert","year":"2012","journal-title":"Natl Vital Stat Rep"},{"key":"10.1016\/j.acra.2016.06.002_bib0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.0030442","article-title":"Projections of global mortality and burden of disease from 2002 to 2030","volume":"3","author":"Mathers","year":"2006","journal-title":"PLoS Med"},{"key":"10.1016\/j.acra.2016.06.002_bib0020","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1164\/ajrccm.161.2.9901044","article-title":"Smoking cessation and lung function in mild-to-moderate chronic obstructive pulmonary disease","volume":"161","author":"Scanlon","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.acra.2016.06.002_bib0025","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0002-9343(99)00056-X","article-title":"Effects of randomized assignment to a smoking cessation intervention and changes in smoking habits on respiratory symptoms in smokers with early chronic obstructive pulmonary disease: the Lung Health Study","volume":"106","author":"Kanner","year":"1999","journal-title":"Am J Med"},{"key":"10.1016\/j.acra.2016.06.002_bib0030","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1378\/chest.13-2220","article-title":"Smoking cessation in COPD causes a transient improvement in spirometry and decreases micronodules on high-resolution CT imaging","volume":"145","author":"Dhariwal","year":"2014","journal-title":"Chest"},{"key":"10.1016\/j.acra.2016.06.002_bib0035","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1148\/radiol.2462070712","article-title":"Fleischner Society: glossary of terms for thoracic imaging","volume":"246","author":"Hansell","year":"2008","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.06.002_bib0040","first-page":"265","article-title":"Morphologic and morphometric effects of prolonged cigarette smoking on the small airways","volume":"122","author":"Cosio","year":"1980","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.acra.2016.06.002_bib0045","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2214\/ajr.161.1.8517318","article-title":"CT findings in a proved case of respiratory bronchiolitis","volume":"161","author":"Gruden","year":"1993","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.acra.2016.06.002_bib0050","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0009-9260(98)80312-7","article-title":"Imaging the \u201cdirty lung\u201d\u2014has high resolution computed tomography cleared the smoke?","volume":"53","author":"Guckel","year":"1998","journal-title":"Clin Radiol"},{"key":"10.1016\/j.acra.2016.06.002_bib0055","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.2214\/ajr.173.6.10584810","article-title":"Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process?","volume":"173","author":"Heyneman","year":"1999","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.acra.2016.06.002_bib0060","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1136\/thx.54.11.1009","article-title":"Clinical significance of respiratory bronchiolitis on open lung biopsy and its relationship to smoking related interstitial lung disease","volume":"54","author":"Moon","year":"1999","journal-title":"Thorax"},{"key":"10.1016\/j.acra.2016.06.002_bib0065","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1148\/radiol.2221001154","article-title":"Longitudinal follow-up study of smoker's lung with thin-section CT in correlation with pulmonary function tests","volume":"222","author":"Remy-Jardin","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.06.002_bib0070","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1148\/radiology.218.3.r01mr08695","article-title":"Thin-section CT finding in 250 volunteers: assessment of the relationship of CT findings with smoking history and pulmonary function test results","volume":"218","author":"Mastora","year":"2001","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.06.002_bib0075","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1378\/chest.06-1040","article-title":"Interobserver variability in the determination of upper lobe-predominant emphysema","volume":"131","author":"Hersh","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.acra.2016.06.002_bib0080","doi-asserted-by":"crossref","first-page":"151","DOI":"10.3109\/15412555.2012.654923","article-title":"A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation","volume":"9","author":"Lynch","year":"2012","journal-title":"COPD"},{"key":"10.1016\/j.acra.2016.06.002_bib0085","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1007\/s00330-009-1437-z","article-title":"Fully automatic quantitative assessment of emphysema in computed tomography: comparison with pulmonary function testing and normal values","volume":"19","author":"Heussel","year":"2009","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2016.06.002_bib0090","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3109\/15412550903499522","article-title":"Genetic epidemiology of COPD (COPDGene) study design","volume":"7","author":"Regan","year":"2010","journal-title":"COPD"},{"key":"10.1016\/j.acra.2016.06.002_bib0095","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1164\/ajrccm.162.3.9907120","article-title":"Computed tomographic measurements of airway dimensions and emphysema in smokers","volume":"162","author":"Nakano","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.acra.2016.06.002_bib0100","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S2213-2600(13)70006-7","article-title":"The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study","volume":"1","author":"Coxson","year":"2013","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.acra.2016.06.002_bib0105","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1109\/TMI.2006.870889","article-title":"MDCT-based 3-D texture classification of emphysema and early smoking related lung pathologies","volume":"25","author":"Xu","year":"2006","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1016\/j.acra.2016.06.002_bib0110","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/RLI.0b013e31816901c7","article-title":"Texture-based quantification of pulmonary emphysema on high-resolution computed tomography: comparison with density-based quantification and correlation with pulmonary function tests","volume":"43","author":"Park","year":"2008","journal-title":"Invest Radiol"},{"key":"10.1016\/j.acra.2016.06.002_bib0115","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1109\/TMI.2009.2038575","article-title":"Quantitative analysis of pulmonary emphysema using local binary patterns","volume":"29","author":"Sorensen","year":"2010","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1016\/j.acra.2016.06.002_bib0120","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/j.acra.2012.04.020","article-title":"Automated texture-based quantification of centrilobular nodularity and centrilobular emphysema in chest CT images","volume":"19","author":"Ginsburg","year":"2012","journal-title":"Acad Radiol"},{"key":"10.1016\/j.acra.2016.06.002_bib0125","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1056\/NEJM197410102911503","article-title":"Pathologic changes in the peripheral airways of young cigarette smokers","volume":"291","author":"Niewoehner","year":"1974","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acra.2016.06.002_bib0130","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1097\/RCT.0b013e3181ef9fbe","article-title":"Repeated low-dose computed tomography in current and former smokers for quantification of emphysema","volume":"34","author":"McGregor","year":"2010","journal-title":"J Comput Assist Tomogr"},{"key":"10.1016\/j.acra.2016.06.002_bib0135","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1136\/thx.2009.132688","article-title":"Short-term effect of changes in smoking behavior on emphysema quantification by CT","volume":"66","author":"Ashraf","year":"2011","journal-title":"Thorax"},{"key":"10.1016\/j.acra.2016.06.002_bib0140","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/RLI.0b013e318262292e","article-title":"Quantitative computed tomography of the lungs and airways in healthy nonsmoking adults","volume":"47","author":"Zach","year":"2012","journal-title":"Invest Radiol"},{"key":"10.1016\/j.acra.2016.06.002_bib0145","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/RTI.0000000000000181","article-title":"Current smoking status is associated with lower quantitative CT measures of emphysema and gas trapping","volume":"31","author":"Zach","year":"2016","journal-title":"J Thorac Imaging"},{"key":"10.1016\/j.acra.2016.06.002_bib0150","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1148\/radiol.11110173","article-title":"Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes","volume":"261","author":"Han","year":"2011","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.06.002_bib0155","series-title":"The elements of statistical learning: data mining, inference, and prediction","author":"Hastie","year":"2001"},{"key":"10.1016\/j.acra.2016.06.002_bib0160","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000195837","article-title":"The \u201chealthy smoker\u201d: a phenomenon of health selection?","volume":"57","author":"Becklake","year":"1990","journal-title":"Respiration"},{"key":"10.1016\/j.acra.2016.06.002_bib0165","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1118\/1.598454","article-title":"On segmentation of lung parenchyma in quantitative computed tomography of the lung","volume":"25","author":"Kemerink","year":"1997","journal-title":"Med Phys"},{"key":"10.1016\/j.acra.2016.06.002_bib0170","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1148\/radiol.2321030383","article-title":"Emphysema: effect of reconstruction algorithm on CT imaging measures","volume":"232","author":"Boedeker","year":"2004","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2016.06.002_bib0175","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1164\/ajrccm.154.1.8680679","article-title":"Comparison of computed density and microscopic morphometry in pulmonary emphysema","volume":"154","author":"Genevois","year":"1996","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.acra.2016.06.002_bib0180","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1164\/ajrccm.159.3.9805067","article-title":"A quantification of the lung surface area in emphysema using computed tomography","volume":"159","author":"Coxson","year":"1999","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633216301040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633216301040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T21:55:33Z","timestamp":1536443733000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633216301040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":35,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S1076633216301040"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2016.06.002","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Texture-based Quantification of Centrilobular Emphysema and Centrilobular Nodularity in Longitudinal CT Scans of Current and Former Smokers","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2016.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}