{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:55:57Z","timestamp":1792648557303,"version":"4.5.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["CIF#97687"],"award-info":[{"award-number":["CIF#97687"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.acra.2017.08.010","type":"journal-article","created":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T18:03:01Z","timestamp":1508176981000},"page":"159-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["On the Potential Role of MRI Biomarkers of COPD to Guide Bronchoscopic Lung Volume Reduction"],"prefix":"10.1016","volume":"25","author":[{"given":"Colin J.","family":"Adams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dante P.I.","family":"Capaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Di Cesare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"McCormack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Parraga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.acra.2017.08.010_bib0010","doi-asserted-by":"crossref","first-page":"2645","DOI":"10.1056\/NEJMoa032158","article-title":"The nature of small-airway obstruction in chronic obstructive pulmonary disease","volume":"350","author":"Hogg","year":"2004","journal-title":"NEJM"},{"key":"10.1016\/j.acra.2017.08.010_bib0015","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1164\/ajrccm.163.5.2101039","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease","volume":"163","author":"Pauwels","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0020","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1056\/NEJMoa0909883","article-title":"Susceptibility to exacerbation in chronic obstructive pulmonary disease","volume":"363","author":"Hurst","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0025","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4104\/pcrj.2013.00025","article-title":"No room to breathe: the importance of lung hyperinflation in COPD","volume":"22","author":"Thomas","year":"2013","journal-title":"Prim Care Respir J"},{"key":"10.1016\/j.acra.2017.08.010_bib0030","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1159\/000256510","article-title":"Endoscopic lung volume reduction","volume":"79","author":"Herth","year":"2009","journal-title":"Respiration"},{"key":"10.1016\/j.acra.2017.08.010_bib0035","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1136\/thoraxjnl-2014-205221","article-title":"Lung volume reduction coil treatment for patients with severe emphysema: a European multicentre trial","volume":"69","author":"Deslee","year":"2014","journal-title":"Thorax"},{"key":"10.1016\/j.acra.2017.08.010_bib0040","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S2213-2600(16)00045-X","article-title":"Segmental volume reduction using thermal vapour ablation in patients with severe emphysema: 6-month results of the multicentre, parallel-group, open-label, randomised controlled STEP-UP trial","volume":"4","author":"Herth","year":"2016","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0045","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1378\/chest.110.1.205","article-title":"Lung volume reduction surgery for emphysema","volume":"110","author":"Brenner","year":"1996","journal-title":"Chest"},{"key":"10.1016\/j.acra.2017.08.010_bib0050","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0022-5223(96)70147-2","article-title":"Results of 150 consecutive bilateral lung volume reduction procedures in patients with severe emphysema","volume":"112","author":"Cooper","year":"1996","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.acra.2017.08.010_bib0055","first-page":"1075","article-title":"Patients at high risk of death after lung-volume\u2013reduction surgery","volume":"2001","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0060","doi-asserted-by":"crossref","first-page":"721","DOI":"10.7196\/SAMJnew.8144","article-title":"Endoscopic lung volume reduction in severe emphysema","volume":"105","author":"Koegelenberg","year":"2015","journal-title":"S Afr Med J"},{"key":"10.1016\/j.acra.2017.08.010_bib0065","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.athoracsur.2006.05.069","article-title":"Long-term follow-up of patients receiving lung-volume-reduction surgery versus medical therapy for severe emphysema by the National Emphysema Treatment Trial Research Group","volume":"82","author":"Naunheim","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.acra.2017.08.010_bib0070","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1164\/rccm.201103-0455CI","article-title":"The National Emphysema Treatment Trial (NETT) part II: lessons learned about lung volume reduction surgery","volume":"184","author":"Criner","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0075","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/S0140-6736(15)60001-0","article-title":"Bronchoscopic lung volume reduction with endobronchial valves for patients with heterogeneous emphysema and intact interlobar fissures (the BeLieVeR-HIFi study): a randomised controlled trial","volume":"386","author":"Davey","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.acra.2017.08.010_bib0080","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1183\/09031936.00092411","article-title":"Bronchoscopic thermal vapour ablation therapy in the management of heterogeneous emphysema","volume":"39","author":"Snell","year":"2012","journal-title":"Eur Respir J"},{"key":"10.1016\/j.acra.2017.08.010_bib0085","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S2213-2600(13)70047-X","article-title":"Endobronchial coils for the treatment of severe emphysema with hyperinflation (RESET): a randomised controlled trial","volume":"1","author":"Shah","year":"2013","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0090","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1056\/NEJMoa1507807","article-title":"Endobronchial valves for emphysema without interlobar collateral ventilation","volume":"373","author":"Klooster","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0095","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1001\/jama.2015.17821","article-title":"Lung volume reduction coil treatment vs usual care in patients with severe emphysema: the REVOLENS Randomized Clinical Trial","volume":"315","author":"Deslee","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.acra.2017.08.010_bib0100","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1056\/NEJMoa0900928","article-title":"A randomized study of endobronchial valves for advanced emphysema","volume":"363","author":"Sciurba","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0105","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1056\/NEJMoa030287","article-title":"A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema","volume":"348","author":"Fishman","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0110","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1159\/000354175","article-title":"The localized inflammatory response to bronchoscopic thermal vapor ablation","volume":"86","author":"Gompelmann","year":"2013","journal-title":"Respiration"},{"key":"10.1016\/j.acra.2017.08.010_bib0115","first-page":"397","article-title":"Characterization of outcomes 1 year after endoscopic thermal vapor ablation for patients with heterogeneous emphysema","volume":"7","author":"Herth","year":"2012","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"10.1016\/j.acra.2017.08.010_bib0120","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1148\/radiol.2221001834","article-title":"Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes\u2014initial experience","volume":"222","author":"Salerno","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0125","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1148\/radiology.210.3.r99fe08851","article-title":"Lung air spaces: MR imaging evaluation with hyperpolarized 3He gas","volume":"210","author":"de Lange","year":"1999","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0130","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.ejrad.2009.10.028","article-title":"Hyperpolarized 3 He magnetic resonance imaging: preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease","volume":"79","author":"Mathew","year":"2011","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.acra.2017.08.010_bib0135","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1148\/radiol.14140161","article-title":"Hyperpolarized (3)He ventilation defects used to predict pulmonary exacerbations in mild to moderate chronic obstructive pulmonary disease","volume":"273","author":"Kirby","year":"2014","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0140","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1148\/radiol.10091937","article-title":"Chronic obstructive pulmonary disease: longitudinal hyperpolarized 3He MR imaging 1","volume":"256","author":"Kirby","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0145","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/01.rli.0000262571.81771.66","article-title":"Hyperpolarized 3He ventilation defects and apparent diffusion coefficients in chronic obstructive pulmonary disease: preliminary results at 3.0 Tesla","volume":"42","author":"Parraga","year":"2007","journal-title":"Invest Radiol"},{"key":"10.1016\/j.acra.2017.08.010_bib0150","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1148\/radiology.201.2.8888259","article-title":"Normal and abnormal pulmonary ventilation: visualization at hyperpolarized He-3 MR imaging","volume":"201","author":"Kauczor","year":"1996","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0155","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1148\/radiol.2015151484","article-title":"Pulmonary imaging biomarkers of gas trapping and emphysema in COPD: He-3 MR imaging and CT parametric response maps","volume":"279","author":"Capaldi","year":"2016","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0160","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1148\/radiol.12120485","article-title":"Hyperpolarized 3He and 129Xe MR imaging in healthy volunteers and patients with chronic obstructive pulmonary disease","volume":"265","author":"Kirby","year":"2012","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0165","first-page":"200","article-title":"Longitudinal computed tomography and magnetic resonance imaging of COPD: Thoracic Imaging Network of Canada (TINCan) study objectives","volume":"1","author":"Kirby","year":"2014","journal-title":"Chronic Obstr Pulm Dis"},{"key":"10.1016\/j.acra.2017.08.010_bib0170","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1164\/rccm.201204-0596PP","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary","volume":"187","author":"Vestbo","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0175","doi-asserted-by":"crossref","first-page":"W460","DOI":"10.2214\/AJR.12.10102","article-title":"Relationships between airflow obstruction and quantitative CT measurements of emphysema, air trapping, and airways in subjects with and without chronic obstructive pulmonary disease","volume":"201","author":"Schroeder","year":"2013","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.acra.2017.08.010_bib0180","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1183\/09031936.05.00034805","article-title":"Standardisation of spirometry","volume":"26","author":"Miller","year":"2005","journal-title":"Eur Respir J"},{"key":"10.1016\/j.acra.2017.08.010_bib0185","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1183\/09031936.05.00035005","article-title":"Standardisation of the measurement of lung volumes","volume":"26","author":"Wanger","year":"2005","journal-title":"Eur Respir J"},{"issue":"suppl B","key":"10.1016\/j.acra.2017.08.010_bib0190","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0954-6111(06)80166-6","article-title":"The St George's Respiratory Questionnaire","volume":"85","author":"Jones","year":"1991","journal-title":"Respir Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0195","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1183\/09031936.00150314","article-title":"An official European Respiratory Society\/American Thoracic Society technical standard: field walking tests in chronic respiratory disease","volume":"44","author":"Holland","year":"2014","journal-title":"Eur Respir J"},{"key":"10.1016\/j.acra.2017.08.010_bib0200","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.acra.2011.10.007","article-title":"Hyperpolarized 3 He magnetic resonance functional imaging semiautomated segmentation","volume":"19","author":"Kirby","year":"2012","journal-title":"Acad Radiol"},{"key":"10.1016\/j.acra.2017.08.010_bib0205","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ejro.2015.05.003","article-title":"Magnetic resonance imaging biomarkers of chronic obstructive pulmonary disease prior to radiation therapy for non-small cell lung cancer","volume":"2","author":"Sheikh","year":"2015","journal-title":"Eur J Radiol Open"},{"key":"10.1016\/j.acra.2017.08.010_bib0210","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.media.2012.05.008","article-title":"MIND: Modality Independent Neighbourhood Descriptor for multi-modal deformable registration","volume":"16","author":"Heinrich","year":"2012","journal-title":"Med Image Anal"},{"key":"10.1016\/j.acra.2017.08.010_bib0215","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2307\/1932409","article-title":"Measures of the amount of ecologic association between species","volume":"26","author":"Dice","year":"1945","journal-title":"Ecology"},{"key":"10.1016\/j.acra.2017.08.010_bib0220","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1148\/radiol.2443061330","article-title":"Monitoring of smoking-induced emphysema with CT in a lung cancer screening setting: detection of real increase in extent of emphysema","volume":"244","author":"Gietema","year":"2007","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2017.08.010_bib0225","doi-asserted-by":"crossref","first-page":"276","DOI":"10.11613\/BM.2012.031","article-title":"Interrater reliability: the Kappa statistic","volume":"22","author":"McHugh","year":"2012","journal-title":"Biochem Med (Zagreb)"},{"key":"10.1016\/j.acra.2017.08.010_bib0230","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1136\/thoraxjnl-2013-203743","article-title":"Current status of bronchoscopic lung volume reduction with endobronchial valves","volume":"69","author":"Shah","year":"2014","journal-title":"Thorax"},{"key":"10.1016\/j.acra.2017.08.010_bib0235","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/1465-9921-11-122","article-title":"Characterisation of COPD heterogeneity in the ECLIPSE cohort","volume":"11","author":"Agusti","year":"2010","journal-title":"Respir Res"},{"key":"10.1016\/j.acra.2017.08.010_bib0240","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1136\/thoraxjnl-2011-201185","article-title":"Relationship between quantitative CT metrics and health status and BODE in chronic obstructive pulmonary disease","volume":"67","author":"Martinez","year":"2012","journal-title":"Thorax"},{"key":"10.1016\/j.acra.2017.08.010_bib0245","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.rmed.2013.04.016","article-title":"Impact of emphysema and airway wall thickness on quality of life in smoking-related COPD","volume":"107","author":"Gietema","year":"2013","journal-title":"Respir Med"},{"key":"10.1016\/j.acra.2017.08.010_bib0250","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1055\/s-2005-837631","article-title":"Surgical treatment for lung cancer with COPD based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD)","volume":"53","author":"Iwasaki","year":"2005","journal-title":"Thorac Cardiov Surg"},{"key":"10.1016\/j.acra.2017.08.010_bib0255","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.ijrobp.2011.03.005","article-title":"Curative treatment of stage I non-small-cell lung cancer in patients with severe COPD: stereotactic radiotherapy outcomes and systematic review","volume":"82","author":"Palma","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.acra.2017.08.010_bib0260","doi-asserted-by":"crossref","first-page":"161s","DOI":"10.1378\/chest.07-1359","article-title":"Physiologic evaluation of the patient with lung cancer being considered for resectional surgery\u2014ACCP evidenced-based clinical practice guidelines (2nd edition)","volume":"132","author":"Colice","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.acra.2017.08.010_bib0265","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1002\/mrm.22697","article-title":"Diffusion-weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease","volume":"65","author":"Kaushik","year":"2011","journal-title":"Magn Reson Med"},{"issue":"suppl 3","key":"10.1016\/j.acra.2017.08.010_bib0270","doi-asserted-by":"crossref","first-page":"A220","DOI":"10.1136\/thoraxjnl-2015-207770.419","article-title":"P283 Hyperpolarised gas MRI\u2014a pathway to clinical diagnostic imaging","volume":"70","author":"Wild","year":"2015","journal-title":"Thorax"},{"key":"10.1016\/j.acra.2017.08.010_bib0275","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1002\/mrm.24570","article-title":"Optimized 3D ultrashort echo time pulmonary MRI","volume":"70","author":"Johnson","year":"2013","journal-title":"Magn Reson Med"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633217303689?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633217303689?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,26]],"date-time":"2018-08-26T21:52:19Z","timestamp":1535320339000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633217303689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S1076633217303689"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2017.08.010","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"On the Potential Role of MRI Biomarkers of COPD to Guide Bronchoscopic Lung Volume Reduction","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2017.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}