{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:22:53Z","timestamp":1791973373464,"version":"4.3.4"},"reference-count":50,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T00:00:00Z","timestamp":1520467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.acra.2018.02.010","type":"journal-article","created":{"date-parts":[[2018,4,4]],"date-time":"2018-04-04T12:01:53Z","timestamp":1522843313000},"page":"1405-1414","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Multiparametric Whole-body MRI with Diffusion-weighted Imaging and ADC Mapping for the Identification of Visceral and Osseous Metastases From Solid Tumors"],"prefix":"10.1016","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1125-1644","authenticated-orcid":false,"given":"Michael A.","family":"Jacobs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8469-2125","authenticated-orcid":false,"given":"Katarzyna J.","family":"Macura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atif","family":"Zaheer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel S.","family":"Antonarakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vered","family":"Stearns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio C.","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Feiweier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ihab R.","family":"Kamel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L.","family":"Wahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4 suppl 5","key":"10.1016\/j.acra.2018.02.010_bib0010","first-page":"11","article-title":"Bone metastases in breast cancer patients","volume":"18","author":"Hortobagyi","year":"1991","journal-title":"Semin Oncol"},{"key":"10.1016\/j.acra.2018.02.010_bib0015","doi-asserted-by":"crossref","first-page":"4951","DOI":"10.1158\/0008-5472.CAN-09-0099","article-title":"Breast cancer metastasis: challenges and opportunities","volume":"69","author":"Lu","year":"2009","journal-title":"Cancer Res"},{"key":"10.1016\/j.acra.2018.02.010_bib0020","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1200\/JCO.1998.16.10.3375","article-title":"Detection of bone metastases in breast cancer by 18FDG PET: differing metabolic activity in osteoblastic and osteolytic lesions","volume":"16","author":"Cook","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.acra.2018.02.010_bib0025","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1007\/s00330-011-2221-4","article-title":"Diagnosis of bone metastases: a meta-analysis comparing 18FDG PET, CT, MRI and bone scintigraphy","volume":"21","author":"Yang","year":"2011","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0030","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/1099-1492(200010)13:6<321::AID-NBM651>3.0.CO;2-P","article-title":"Bone marrow segmentation in leukemia using diffusion and T (2) weighted echo planar magnetic resonance imaging","volume":"13","author":"Ballon","year":"2000","journal-title":"NMR Biomed"},{"key":"10.1016\/j.acra.2018.02.010_bib0035","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2214\/ajr.177.1.1770229","article-title":"Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET","volume":"177","author":"Daldrup-Link","year":"2001","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.acra.2018.02.010_bib0040","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2214\/ajr.180.1.1800247","article-title":"Current concepts in whole-body imaging using turbo short tau inversion recovery MR imaging","volume":"180","author":"Hargaden","year":"2003","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.acra.2018.02.010_bib0045","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.ejso.2005.09.018","article-title":"Whole body MR imaging: applications in oncology","volume":"32","author":"Johnston","year":"2006","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.acra.2018.02.010_bib0050","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1002\/jmri.21074","article-title":"Whole-body diffusion-weighted imaging: technical improvement and preliminary results","volume":"26","author":"Li","year":"2007","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.acra.2018.02.010_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11547-008-0348-4","article-title":"Whole-body diffusion-weighted magnetic resonance imaging in the staging of oncological patients: comparison with positron emission tomography computed tomography (PET-CT) in a pilot study","volume":"114","author":"Stecco","year":"2009","journal-title":"Radiol Med"},{"key":"10.1016\/j.acra.2018.02.010_bib0060","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1007\/s00330-013-2794-1","article-title":"Assessment of therapeutic response in ankylosing spondylitis patients undergoing anti-tumour necrosis factor therapy by whole-body magnetic resonance imaging","volume":"23","author":"Karpitschka","year":"2013","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0091779","article-title":"Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study","volume":"9","author":"Blackledge","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.acra.2018.02.010_bib0070","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1002\/jmri.25293","article-title":"Whole-body MR neurography: prospective feasibility study in polyneuropathy and Charcot-Marie-Tooth disease","volume":"44","author":"Chhabra","year":"2016","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.acra.2018.02.010_bib0075","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1080\/03009742.2016.1231338","article-title":"Monitoring total-body inflammation and damage in joints and entheses: the first follow-up study of whole-body magnetic resonance imaging in rheumatoid arthritis","volume":"46","author":"Axelsen","year":"2017","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.acra.2018.02.010_bib0080","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1093\/jnci\/92.24.2029","article-title":"Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors","volume":"92","author":"Chenevert","year":"2000","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.acra.2018.02.010_bib0085","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.crad.2008.02.001","article-title":"Diffusion-weighted magnetic resonance imaging: a potential non-invasive marker of tumour aggressiveness in localized prostate cancer","volume":"63","author":"de Souza","year":"2008","journal-title":"Clin Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0090","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1593\/neo.81328","article-title":"Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations","volume":"11","author":"Padhani","year":"2009","journal-title":"Neoplasia"},{"key":"10.1016\/j.acra.2018.02.010_bib0095","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1148\/radiol.10091367","article-title":"Diffusion-weighted imaging improves the diagnostic accuracy of conventional 3.0-T breast MR imaging","volume":"256","author":"Ei Khouli","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.02.010_bib0100","first-page":"275","article-title":"Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display","volume":"22","author":"Takahara","year":"2004","journal-title":"Radiat Med"},{"key":"10.1016\/j.acra.2018.02.010_bib0105","doi-asserted-by":"crossref","first-page":"211","DOI":"10.2463\/mrms.6.211","article-title":"Practical aspects of assessing tumors using clinical diffusion-weighted imaging in the body","volume":"6","author":"Koh","year":"2007","journal-title":"Magn Reson Med Sci"},{"key":"10.1016\/j.acra.2018.02.010_bib0110","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1148\/radiol.2482072039","article-title":"Non-small cell lung cancer: whole-body MR examination for M-stage assessment\u2013utility for whole-body diffusion-weighted imaging compared with integrated FDG PET\/CT","volume":"248","author":"Ohno","year":"2008","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.02.010_bib0115","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.ejrad.2008.02.040","article-title":"Diffusion-weighted whole-body MR screening","volume":"67","author":"Vilanova","year":"2008","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0120","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1007\/s00259-010-1399-z","article-title":"Diagnostic value of diffusion-weighted magnetic resonance imaging (DWI) compared to FDG PET\/CT for whole-body breast cancer staging","volume":"37","author":"Heusner","year":"2010","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.acra.2018.02.010_bib0125","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/RLI.0b013e3182087b03","article-title":"Whole-body diffusion-weighted imaging with apparent diffusion coefficient mapping for treatment response assessment in patients with diffuse large B-cell lymphoma: pilot study","volume":"46","author":"Lin","year":"2011","journal-title":"Invest Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0130","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ejrad.2007.10.021","article-title":"Comprehensive imaging of tumor recurrence in breast cancer patients using whole-body MRI at 1.5 and 3 T compared to FDG-PET-CT","volume":"65","author":"Schmidt","year":"2008","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0135","doi-asserted-by":"crossref","first-page":"9","DOI":"10.5402\/2013\/627932","article-title":"Whole body MRI at 3T with quantitative diffusion weighted imaging and contrast-enhanced sequences for the characterization of peripheral lesions in patients with neurofibromatosis type 2 and schwannomatosis","volume":"2013","author":"Fayad","year":"2013","journal-title":"ISRN Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0140","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1002\/jmri.25236","article-title":"Multiparametric whole-body anatomic, functional, and metabolic imaging characteristics of peripheral lesions in patients with schwannomatosis","volume":"44","author":"Ahlawat","year":"2016","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.acra.2018.02.010_bib0145","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1148\/radiology.188.1.8511306","article-title":"Bull's-eyes and halos: useful MR discriminators of osseous metastases","volume":"188","author":"Schweitzer","year":"1993","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.02.010_bib0150","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2214\/ajr.162.1.8273669","article-title":"MR imaging of bone marrow lesions: relative conspicuousness on T1-weighted, fat-suppressed T2-weighted, and STIR images","volume":"162","author":"Mirowitz","year":"1994","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.acra.2018.02.010_bib0155","first-page":"1431","article-title":"Understanding the standardized uptake value, its methods, and implications for usage","volume":"45","author":"Thie","year":"2004","journal-title":"J Nucl Med"},{"issue":"suppl 1","key":"10.1016\/j.acra.2018.02.010_bib0160","doi-asserted-by":"crossref","first-page":"122S","DOI":"10.2967\/jnumed.108.057307","article-title":"From RECIST to PERCIST: evolving considerations for PET response criteria in solid tumors","volume":"50","author":"Wahl","year":"2009","journal-title":"J Nucl Med"},{"key":"10.1016\/j.acra.2018.02.010_bib0165","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.2214\/AJR.05.0778","article-title":"ADC measurement of abdominal organs and lesions using parallel imaging technique","volume":"187","author":"Yoshikawa","year":"2006","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.acra.2018.02.010_bib0170","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1016\/j.ejrad.2009.05.040","article-title":"Role of magnetic resonance diffusion-weighted imaging in evaluating response after chemoembolization of hepatocellular carcinoma","volume":"75","author":"Yuan","year":"2010","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0175","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1002\/jmri.22542","article-title":"Whole-body MRI including diffusion-weighted imaging (DWI) for patients with recurring prostate cancer: technical feasibility and assessment of lesion conspicuity in DWI","volume":"33","author":"Eiber","year":"2011","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.acra.2018.02.010_bib0180","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1002\/jmri.23537","article-title":"Three-year follow-up of human transplanted kidneys by diffusion-weighted MRI and blood oxygenation level-dependent imaging","volume":"35","author":"Vermathen","year":"2012","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.acra.2018.02.010_bib0185","doi-asserted-by":"crossref","first-page":"242","DOI":"10.2214\/AJR.14.13964","article-title":"Apparent diffusion coefficient of normal abdominal organs and bone marrow from whole-body DWI at 1.5 T: the effect of sex and age","volume":"205","author":"Lavdas","year":"2015","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.acra.2018.02.010_bib0190","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.2214\/AJR.07.2512","article-title":"Diffusion-weighted imaging of the appendicular skeleton with a non-Carr-Purcell-Meiboom-Gill single-shot fast spin-echo sequence","volume":"189","author":"Oner","year":"2007","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.acra.2018.02.010_bib0195","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1007\/s00330-011-2221-4","article-title":"Diagnosis of bone metastases: a meta-analysis comparing (1)(8)FDG PET, CT, MRI and bone scintigraphy","volume":"21","author":"Yang","year":"2011","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0200","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.eururo.2012.02.020","article-title":"Can whole-body magnetic resonance imaging with diffusion-weighted imaging replace Tc 99m bone scanning and computed tomography for single-step detection of metastases in patients with high-risk prostate cancer?","volume":"62","author":"Lecouvet","year":"2012","journal-title":"Eur Urol"},{"key":"10.1016\/j.acra.2018.02.010_bib0205","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1007\/s00256-014-1903-9","article-title":"Comparison of choline-PET\/CT, MRI, SPECT, and bone scintigraphy in the diagnosis of bone metastases in patients with prostate cancer: a meta-analysis","volume":"43","author":"Shen","year":"2014","journal-title":"Skeletal Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0210","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1148\/radiol.14141242","article-title":"Whole-body 3D T1-weighted MR imaging in patients with prostate cancer: feasibility and evaluation in screening for metastatic disease","volume":"275","author":"Pasoglou","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.02.010_bib0215","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3233\/BD-1998-103-416","article-title":"Positron emission tomography (PET): an update on applications in breast cancer","volume":"10","author":"Wahl","year":"1998","journal-title":"Breast Dis"},{"key":"10.1016\/j.acra.2018.02.010_bib0220","first-page":"1249","article-title":"Imaging prostate cancer with 11C-choline PET\/CT","volume":"47","author":"Reske","year":"2006","journal-title":"J Nucl Med"},{"key":"10.1016\/j.acra.2018.02.010_bib0225","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.acra.2004.07.007","article-title":"Combined use of MRI and PET to monitor response and assess residual disease for locally advanced breast cancer treated with neoadjuvant chemotherapy","volume":"11","author":"Chen","year":"2004","journal-title":"Acad Radiol"},{"key":"10.1016\/j.acra.2018.02.010_bib0230","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/nm1700","article-title":"Simultaneous PET-MRI: a new approach for functional and morphological imaging","volume":"14","author":"Judenhofer","year":"2008","journal-title":"Nat Med"},{"key":"10.1016\/j.acra.2018.02.010_bib0235","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s12282-008-0065-9","article-title":"Comparison of FDG PET and MRI for evaluating the tumor extent of breast cancer and the impact of FDG PET on the systemic staging and prognosis of patients who are candidates for breast-conserving therapy","volume":"16","author":"Uematsu","year":"2009","journal-title":"Breast Cancer"},{"key":"10.1016\/j.acra.2018.02.010_bib0240","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s10549-011-1442-1","article-title":"Monitoring of neoadjuvant chemotherapy using multiparametric, (23)Na sodium MR, and multimodality (PET\/CT\/MRI) imaging in locally advanced breast cancer","volume":"128","author":"Jacobs","year":"2011","journal-title":"Breast Cancer Res Treat"},{"issue":"suppl 1","key":"10.1016\/j.acra.2018.02.010_bib0245","doi-asserted-by":"crossref","first-page":"S113","DOI":"10.1007\/s00259-008-0951-6","article-title":"Combined PET\/MRI: a new dimension in whole-body oncology imaging?","volume":"36","author":"Antoch","year":"2009","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.acra.2018.02.010_bib0250","doi-asserted-by":"crossref","first-page":"928","DOI":"10.2967\/jnumed.112.105338","article-title":"Oncologic PET\/MRI, part 1: tumors of the brain, head and neck, chest, abdomen, and pelvis","volume":"53","author":"Buchbender","year":"2012","journal-title":"J Nucl Med"},{"key":"10.1016\/j.acra.2018.02.010_bib0255","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.2967\/jnumed.112.109306","article-title":"Oncologic PET\/MRI, part 2: bone tumors, soft-tissue tumors, melanoma, and lymphoma","volume":"53","author":"Buchbender","year":"2012","journal-title":"J Nucl Med"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633218300953?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633218300953?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T08:44:51Z","timestamp":1761036291000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633218300953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S1076633218300953"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2018.02.010","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiparametric Whole-body MRI with Diffusion-weighted Imaging and ADC Mapping for the Identification of Visceral and Osseous Metastases From Solid Tumors","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2018.02.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Association of University Radiologists. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}