{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:54:38Z","timestamp":1773327278646,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Cancer Prevention and Research Initiative of Texas","award":["R1308"],"award-info":[{"award-number":["R1308"]}]},{"name":"Cancer Prevention and Research Initiative of Texas","award":["."],"award-info":[{"award-number":["."]}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.acra.2018.05.012","type":"journal-article","created":{"date-parts":[[2018,7,29]],"date-time":"2018-07-29T10:32:17Z","timestamp":1532860337000},"page":"e9-e17","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Multiparametric MRI Characterization of Funaki Types of Uterine Fibroids Considered for MR-Guided High-Intensity Focused Ultrasound (MR-HIFU) Therapy"],"prefix":"10.1016","volume":"26","author":[{"given":"Sajan","family":"Andrews","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"April","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9743-3010","authenticated-orcid":false,"given":"Yin","family":"Xi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Chopra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Staruch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Pedrosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.acra.2018.05.012_bib0001","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1148\/radiol.2262011716","article-title":"Uterine fibroids: uterine artery embolization versus abdominal hysterectomy for treatment\u2014a prospective, randomized, and controlled clinical trial","volume":"226","author":"Pinto","year":"2003","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.05.012_bib0002","first-page":"864","article-title":"Comparison of long-term outcomes of myomectomy and uterine artery embolization.","volume":"100","author":"Broder","year":"2002","journal-title":"Obs Gynecol"},{"key":"10.1016\/j.acra.2018.05.012_bib0003","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1148\/radiol.2271020395","article-title":"MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study","volume":"226","author":"Tempany","year":"2003","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.05.012_bib0004","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.jmig.2007.04.009","article-title":"Mid-term outcome of magnetic resonance-guided focused ultrasound surgery for uterine myomas: from six to twelve months after volume reduction","volume":"14","author":"Funaki","year":"2007","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.acra.2018.05.012_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ajog.2006.08.030","article-title":"Magnetic resonance-guided focused ultrasound surgery for uterine fibroids: relationship between the therapeutic effects and signal intensity of preexisting T2-weighted magnetic resonance images","volume":"196","author":"Funaki","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.acra.2018.05.012_bib0006","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.acra.2011.03.008","article-title":"MR-guided high intensity focused ultrasound for symptomatic uterine leiomyomata: long-term outcomes","volume":"18","author":"Kim","year":"2011","journal-title":"Acad Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0007","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1148\/radiographics.19.suppl_1.g99oc04s131","article-title":"Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds","volume":"19","author":"Ueda","year":"1999","journal-title":"Radiographics"},{"key":"10.1016\/j.acra.2018.05.012_bib0008","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1080\/02841850600965047","article-title":"Role of magnetic resonance imaging in patient selection for uterine artery embolization","volume":"10","author":"Cura","year":"2006","journal-title":"Acta Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0009","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.jvir.2012.02.015","article-title":"Magnetic resonance imaging-guided volumetric ablation of symptomatic leiomyomata: correlation of imaging with histology","volume":"23","author":"Venkatesan","year":"2012","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0010","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1148\/radiol.2491071600","article-title":"Uterine leiomyomas: MR imaging-guided focused ultrasound surgery\u2013imaging predictors of success","volume":"249","author":"L\u00e9n\u00e1rd","year":"2008","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.05.012_bib0011","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1093\/humrep\/des333","article-title":"MR-guided focus ultrasound (MRgFUS) for symptomatic uterine fibroids: predictors of treatment success","volume":"27","author":"Machtinger","year":"2012","journal-title":"Hum Reprod"},{"key":"10.1016\/j.acra.2018.05.012_bib0012","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1007\/s00330-015-3806-0","article-title":"Scaled signal intensity of uterine fibroids based on T2-weighted MR images: a potential objective method to determine the suitability for magnetic resonance-guided focused ultrasound surgery of uterine fibroids","volume":"25","author":"Park","year":"2015","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0013","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1148\/radiol.14132719","article-title":"Uterine fibroids: semiquantitative perfusion MR imaging parameters associated with the intraprocedural and immediate postprocedural treatment efficiencies of MR imaging-guided high-intensity focused ultrasound ablation","volume":"273","author":"Kim","year":"2014","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.05.012_bib0014","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1097\/RLI.0b013e318220785c","article-title":"Dynamic contrast-enhanced magnetic resonance imaging predicts immediate therapeutic response of magnetic resonance-guided high-intensity focused ultrasound ablation of symptomatic uterine fibroids","volume":"46","author":"Kim","year":"2011","journal-title":"Invest Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0015","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1007\/s00330-014-3538-6","article-title":"MRI predictors of clinical success in MR-guided focused ultrasound (MRgFUS) treatments of uterine fibroids: results from a single centre","volume":"25","author":"Mindjuk","year":"2015","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0016","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1148\/radiology.168.2.3393671","article-title":"Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging","volume":"168","author":"Le Bihan","year":"1988","journal-title":"Radiology"},{"key":"10.1016\/j.acra.2018.05.012_bib0017","first-page":"1","article-title":"Screening magnetic resonance imaging\u2014based prediction model for assessing immediate therapeutic response to magnetic resonance imaging-guided high-intensity focused ultrasound ablation of uterine fibroids","volume":"0","author":"Kim","year":"2016","journal-title":"Invest Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.mri.2014.05.005","article-title":"Volume transfer constant (Ktrans) maps from dynamic contrast enhanced MRI as potential guidance for MR-guided High intensity focused ultrasound treatment of hypervascular uterine fibroids","author":"Liu","year":"2014","journal-title":"Magn Reson Imaging"},{"key":"10.1016\/j.acra.2018.05.012_bib0019","first-page":"1216","article-title":"Measured blood loss, clinical features, and outcome in women with heavy periods\u2014a survey with follow-up data","volume":"190","author":"Warner","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.acra.2018.05.012_bib0020","first-page":"1224","article-title":"Menorrhagia II: is the 80-mL blood loss criterion useful in management of complaint of menorrhagia?","volume":"190","author":"Warner","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.acra.2018.05.012_bib0021","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/(SICI)1522-2586(199909)10:3<223::AID-JMRI2>3.0.CO;2-S","article-title":"Estimating kinetic parameters from dynamic contrast-enhanced T1-weighted MRI of a diffusable tracer: standardized quantities and symbols","volume":"10","author":"Tofts","year":"1999","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.acra.2018.05.012_bib0022","article-title":"The predictive value of quantitative DCE metrics for immediate therapeutic response of high untensity focused ultrasound ablation (HIFU) of symptomatic uterine fibroids","author":"Wei","year":"2017","journal-title":"Abdom Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0023","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.jvir.2011.01.458","article-title":"Magnetic resonance-guided focused ultrasound of uterine leiomyomas: review of a 12-month outcome of 130 clinical patients","volume":"22","author":"Gorny","year":"2011","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0024","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.1007\/s00330-013-2915-x","article-title":"Mid-term clinical efficacy of a volumetric magnetic resonance-guided high-intensity focused ultrasound technique for treatment of symptomatic uterine fibroids","volume":"23","author":"Ikink","year":"2013","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0025","first-page":"3693","article-title":"IntraVoxel incoherent motion MRI for the characterization of uterine fibroids before MR-guided high-intensity focused ultrasound ablation","volume":"22","author":"Ikink","year":"2014","journal-title":"Proc Int Soc Magn Reson Med"},{"key":"10.1016\/j.acra.2018.05.012_bib0026","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1118\/1.3475940","article-title":"Comparison between diffusion-weighted imaging, T2-weighted, and postcontrast T1-weighted imaging after MR-guided, high intensity, focused ultrasound treatment of uterine leiomyomata\u202f: preliminary results","volume":"37","author":"Jacobs","year":"2010","journal-title":"Med Phys"},{"key":"10.1016\/j.acra.2018.05.012_bib0027","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.acra.2013.12.007","article-title":"Entropy of T2-weighted imaging combined with apparent diffusion coefficient in prediction of uterine leiomyoma volume response after uterine artery embolization","volume":"21","author":"Cao","year":"2014","journal-title":"Acad Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0028","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4329\/wjr.v7.i7.149","article-title":"Diffusion-weighted and diffusion-tensor imaging of normal and diseased uterus","volume":"7","author":"Kara Bozkurt","year":"2015","journal-title":"World J Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0029","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s00330-008-1185-5","article-title":"Role of diffusion-weighted imaging in the diagnosis of gynecological diseases","volume":"19","author":"Namimoto","year":"2009","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0030","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1080\/02841850902735858","article-title":"Quantitative diffusion-weighted magnetic resonance imaging of normal and diseased uterine zones","volume":"50","author":"Kilickesmez","year":"2009","journal-title":"Acta Radiol"},{"key":"10.1016\/j.acra.2018.05.012_bib0031","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1259\/bjr\/91540172","article-title":"Diffusion-weighted imaging in uterine artery embolisation: do findings correlate with contrast enhancement and volume reduction?","volume":"85","author":"Ananthakrishnan","year":"2012","journal-title":"Br J Radiol"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S107663321830254X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S107663321830254X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T08:45:30Z","timestamp":1761036330000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S107663321830254X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S107663321830254X"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2018.05.012","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiparametric MRI Characterization of Funaki Types of Uterine Fibroids Considered for MR-Guided High-Intensity Focused Ultrasound (MR-HIFU) Therapy","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2018.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}