{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:32:55Z","timestamp":1790670775644,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["Z99 CL999999"],"award-info":[{"award-number":["Z99 CL999999"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.acra.2022.06.013","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T08:15:34Z","timestamp":1658218534000},"page":"1056-1065","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Splenic Size and Volume Measurements in Patients with Chronic Lymphocytic Leukemia"],"prefix":"10.1016","volume":"30","author":[{"given":"Olanrewaju A.","family":"Ogunleye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0826-7290","authenticated-orcid":false,"given":"Li-Yueh","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare C.","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Nierman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Wiestner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth C.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadi","family":"Bagheri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.acra.2022.06.013_bib0001","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1093\/annonc\/mdq621","article-title":"Splenic volume can be a novel predictive parameter for the prognosis of chronic lymphocytic leukemia?","volume":"21","author":"Song","year":"2010","journal-title":"Ann Oncol"},{"issue":"16","key":"10.1016\/j.acra.2022.06.013_bib0002","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1056\/NEJM199510193331606","article-title":"Chronic lymphocytic leukemia","volume":"333","author":"Rozman","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.acra.2022.06.013_bib0003","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.clml.2011.09.090","article-title":"3.1 Natural History of Splenomegaly in CLL from Automated Volumetric Analysis","volume":"11","author":"Linguraru","year":"2011","journal-title":"Clin Lymph, Myel Leuk"},{"issue":"2","key":"10.1016\/j.acra.2022.06.013_bib0004","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1007\/s11604-017-0704-1","article-title":"Determination of splenomegaly by coronal oblique length on CT","volume":"36","author":"Gunes","year":"2018","journal-title":"Japanese J radiol"},{"issue":"1","key":"10.1016\/j.acra.2022.06.013_bib0005","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1600-0609.1989.tb01253.x","article-title":"The splenomegaly of myeloproliferative and lymphoproliferative disorders: splenic cellularity and vascularity","volume":"43","author":"Zhang","year":"1989","journal-title":"Eur J Haematol"},{"issue":"11","key":"10.1016\/j.acra.2022.06.013_bib0006","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1038\/leu.2014.122","article-title":"Ibrutinib-induced lymphocytosis in patients with chronic lymphocytic leukemia: correlative analyses from a phase II study","volume":"28","author":"Herman","year":"2014","journal-title":"Leukemia"},{"issue":"895","key":"10.1016\/j.acra.2022.06.013_bib0007","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1259\/bjr.75.895.750573","article-title":"Spleen size: how well do linear ultrasound measurements correlate with three-dimensional CT volume assessments?","volume":"75","author":"Lamb","year":"2002","journal-title":"Br J Radiol"},{"issue":"21","key":"10.1016\/j.acra.2022.06.013_bib0008","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1182\/blood-2017-12-820910","article-title":"Depth and durability of response to ibrutinib in CLL: 5-year follow-up of a phase 2 study","volume":"131","author":"Ahn","year":"2018","journal-title":"Blood"},{"issue":"25","key":"10.1016\/j.acra.2022.06.013_bib0009","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1182\/blood-2017-09-806398","article-title":"iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL","volume":"131","author":"Hallek","year":"2018","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.acra.2022.06.013_bib0010","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1007\/s00261-018-1500-9","article-title":"Spleen enlargement assessment using computed tomography: which coefficient correlates the strongest with the real volume of the spleen?","volume":"43","author":"Kucyba\u0142a","year":"2018","journal-title":"Abdom Radiol"},{"issue":"1","key":"10.1016\/j.acra.2022.06.013_bib0011","doi-asserted-by":"crossref","first-page":"5","DOI":"10.5152\/dir.2019.18587","article-title":"The orthogonal measurements approach in estimating spleen size on CT images","volume":"26","author":"Imamoglu","year":"2020","journal-title":"Diagnost Intervent Radiol"},{"issue":"5","key":"10.1016\/j.acra.2022.06.013_bib0012","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.2214\/ajr.184.5.01841510","article-title":"Determination of splenomegaly by CT: is there a place for a single measurement?","volume":"184","author":"Bezerra","year":"2005","journal-title":"Am J Roentgenol"},{"issue":"27","key":"10.1016\/j.acra.2022.06.013_bib0013","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1200\/JCO.2013.54.8800","article-title":"Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification","volume":"32","author":"Cheson","year":"2014","journal-title":"J Clin Oncol"},{"issue":"7","key":"10.1016\/j.acra.2022.06.013_bib0014","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.acra.2017.02.001","article-title":"Comparative evaluation of three software packages for liver and spleen segmentation and volumetry","volume":"24","author":"Pattanayak","year":"2017","journal-title":"Acad Radiol"},{"issue":"6","key":"10.1016\/j.acra.2022.06.013_bib0015","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.acra.2013.01.011","article-title":"Assessing splenomegaly: automated volumetric analysis of the spleen","volume":"20","author":"Linguraru","year":"2013","journal-title":"Acad Radiol"},{"issue":"2","key":"10.1016\/j.acra.2022.06.013_bib0016","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s002689910031","article-title":"Ultrasound of the spleen","volume":"24","author":"Andrews","year":"2000","journal-title":"World J Surg"},{"issue":"1","key":"10.1016\/j.acra.2022.06.013_bib0017","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1182\/blood.2019003715","article-title":"Clinical and biological implications of target occupancy in CLL treated with the BTK inhibitor acalabrutinib","volume":"136","author":"Sun","year":"2020","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.acra.2022.06.013_bib0018","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s003300050145","article-title":"Determination of normal splenic volume on computed tomography in relation to age, gender and body habitus","volume":"7","author":"Prassopoulos","year":"1997","journal-title":"Eur Radiol"},{"issue":"6","key":"10.1016\/j.acra.2022.06.013_bib0019","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.2214\/ajr.181.6.1811615","article-title":"Estimating splenic volume: sonographic measurements correlated with helical CT determination","volume":"181","author":"Yetter","year":"2003","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.acra.2022.06.013_bib0020","doi-asserted-by":"crossref","unstructured":"Badran DH, Kalbouneh HM, Al-Hadidi MT, et al. Ultrasonographic assessment of splenic volume and its correlation with body parameters in a Jordanian population. Saudi medical journal. 2015;36(8):967.","DOI":"10.15537\/smj.2015.8.11809"},{"issue":"3","key":"10.1016\/j.acra.2022.06.013_bib0021","doi-asserted-by":"crossref","first-page":"209","DOI":"10.7863\/jum.1997.16.3.209","article-title":"Accuracy of ultrasonography in assessing spleen and liver size in patients with Gaucher disease: comparison to computed tomographic measurements","volume":"16","author":"Elstein","year":"1997","journal-title":"J Ultrasound Med"},{"issue":"12","key":"10.1016\/j.acra.2022.06.013_bib0022","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/j.acra.2017.06.006","article-title":"The best single measurement for assessing splenomegaly in patients with cirrhotic liver morphology","volume":"24","author":"Nuffer","year":"2017","journal-title":"Acad Radiol"},{"issue":"5","key":"10.1016\/j.acra.2022.06.013_bib0023","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1740-8261.2001.tb00967.x","article-title":"Ultrasonographic appearance of splenic disease in 101 cats","volume":"42","author":"Hanson","year":"2001","journal-title":"Vet Radiol Ultrasound"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633222003397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633222003397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T08:57:51Z","timestamp":1761037071000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633222003397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S1076633222003397"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2022.06.013","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Splenic Size and Volume Measurements in Patients with Chronic Lymphocytic Leukemia","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2022.06.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of The Association of University Radiologists.","name":"copyright","label":"Copyright"}]}}