{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T18:56:58Z","timestamp":1787597818194,"version":"build-2736575974"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.acra.2023.03.033","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T15:42:49Z","timestamp":1682610169000},"page":"S286-S294","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"S1","title":["Defining Hemodynamic Significance of Renal Artery Stenosis: Insights From a Porcine Model of Graded Renal Artery Stenosis"],"prefix":"10.1016","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6960-5572","authenticated-orcid":false,"given":"Benny","family":"Drieghe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunther","family":"van Loon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelies","family":"Decloedt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Stuyvaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc L.","family":"De Buyzere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Bov\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tine","family":"De Backer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.acra.2023.03.033_bib1","first-page":"431","article-title":"Renal-artery stenosis","volume":"344","author":"Safian","year":"2001","journal-title":"N\u00a0Engl\u00a0J\u00a0Med"},{"issue":"3","key":"10.1016\/j.acra.2023.03.033_bib2","first-page":"443","article-title":"Prevalence of renovascular disease in the elderly: a population-based study","volume":"36","author":"Hansen","year":"2002","journal-title":"J\u00a0Vasc\u00a0Surg"},{"issue":"8917","key":"10.1016\/j.acra.2023.03.033_bib3","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0140-6736(94)93002-3","article-title":"Renal artery stenosis and hypertension","volume":"344","author":"Derkx","year":"1994","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.acra.2023.03.033_bib4","first-page":"575","article-title":"Renovascular hypertension","volume":"6","author":"Ram","year":"1997","journal-title":"Curr\u00a0Opin\u00a0Nephrol\u00a0Hypertens"},{"issue":"1n","key":"10.1016\/j.acra.2023.03.033_bib5","first-page":"46n","article-title":"Prevalence of atherosclerotic renal artery stenosis in patients with atherosclerosis elsewhere","volume":"88","author":"Olin","year":"1990","journal-title":"Am\u00a0J\u00a0Med"},{"issue":"11","key":"10.1016\/j.acra.2023.03.033_bib6","first-page":"1608","article-title":"Renal artery stenosis: prevalence and associated risk factors in patients undergoing routine cardiac catheterization","volume":"2","author":"Harding","year":"1992","journal-title":"J\u00a0A\u00a0Soc\u00a0Nephrol"},{"issue":"11","key":"10.1016\/j.acra.2023.03.033_bib7","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1161\/CIRCULATIONAHA.105.540039","article-title":"Catheter-based therapy for atherosclerotic renal artery stenosis","volume":"113","author":"White","year":"2006","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.acra.2023.03.033_bib8","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S1051-0443(07)61629-7","article-title":"Percutaneous revascularization of the renal arteries: predictors of outcome","volume":"11","author":"Giroux","year":"2000","journal-title":"J Vasc Interv Radiol"},{"issue":"11","key":"10.1016\/j.acra.2023.03.033_bib9","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.4065\/70.11.1041","article-title":"Renal artery angioplasty: technical results and clinical outcome in 320 patients","volume":"70","author":"Bonelli","year":"1995","journal-title":"Mayo Clin\u00a0Proc"},{"issue":"1","key":"10.1016\/j.acra.2023.03.033_bib10","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1148\/radiology.216.1.r00jl0778","article-title":"Stent placement for renal arterial stenosis: where do we stand? A meta-analysis","volume":"216","author":"Leertouwer","year":"2000","journal-title":"Radiology"},{"issue":"11","key":"10.1016\/j.acra.2023.03.033_bib11","first-page":"1849","article-title":"Renal artery revascularization: updated meta-analysis with the CORAL trial","volume":"174","author":"Bavry","year":"2014","journal-title":"JAMA Intern\u00a0Med"},{"issue":"6","key":"10.1016\/j.acra.2023.03.033_bib12","first-page":"1026","article-title":"Atheroemboli during renal artery angioplasty: an ex vivo study","volume":"41","author":"Hiramoto","year":"2005","journal-title":"J\u00a0Vasc\u00a0Surg"},{"issue":"18","key":"10.1016\/j.acra.2023.03.033_bib13","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1161\/01.CIR.0000095031.51492.C5","article-title":"Prognostic significance of small-artery structure in hypertension","volume":"108","author":"Rizzoni","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.acra.2023.03.033_bib14","first-page":"99","article-title":"Role of MDCT renal angiography in determining the anatomical eligibility for renal sympathetic denervation in resistant hypertensive patients","volume":"49","author":"El Sammak","year":"2018","journal-title":"Egypt\u00a0J\u00a0Radiol\u00a0Nucl\u00a0Med"},{"issue":"3","key":"10.1016\/j.acra.2023.03.033_bib15","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1084\/jem.59.3.347","article-title":"Studies on experimental hypertension: I. The production of persistent elevation of systolic blood pressure by means of renal ischemia","volume":"59","author":"Goldblatt","year":"1934","journal-title":"J Exp Med"},{"key":"10.1016\/j.acra.2023.03.033_bib16","first-page":"513","article-title":"Hemodynamic effects of arterial stenosis","volume":"53","author":"May","year":"1963","journal-title":"Surgery"},{"issue":"10","key":"10.1016\/j.acra.2023.03.033_bib17","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1177\/000331979204301006","article-title":"Critical degree of renal arterial stenosis that causes hypertension in dogs","volume":"43","author":"Imanishi","year":"1992","journal-title":"Angiology"},{"issue":"4","key":"10.1016\/j.acra.2023.03.033_bib18","first-page":"821","article-title":"Coronary pressure-function and steady-state pressure-flow relations during autoregulation in the unanesthetized dog","volume":"63","author":"Canty","year":"1988","journal-title":"Circ\u00a0Res"},{"issue":"1","key":"10.1016\/j.acra.2023.03.033_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0002-9149(74)90743-7","article-title":"Physiologic basis for assessing critical coronary stenosis: instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve","volume":"33","author":"Gould","year":"1974","journal-title":"Am\u00a0J\u00a0Cardiol"},{"issue":"2","key":"10.1016\/j.acra.2023.03.033_bib20","first-page":"242","article-title":"Pressure-flow characteristics of coronary stenoses in unsedated dogs at rest and during coronary vasodilation","volume":"43","author":"Gould","year":"1978","journal-title":"Circ\u00a0Res"},{"issue":"26","key":"10.1016\/j.acra.2023.03.033_bib21","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1056\/NEJM199606273342604","article-title":"Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses","volume":"334","author":"Pijls","year":"1996","journal-title":"New Engl\u00a0J\u00a0Med"},{"key":"10.1016\/j.acra.2023.03.033_bib22","series-title":"Guide for the care and use of laboratory animals","year":"1996"},{"issue":"12","key":"10.1016\/j.acra.2023.03.033_bib23","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1097\/00004872-199917120-00011","article-title":"Interpretation of renal angiography by radiologists","volume":"17","author":"Schreij","year":"1999","journal-title":"J\u00a0Hypertens"},{"issue":"3","key":"10.1016\/j.acra.2023.03.033_bib24","first-page":"429","article-title":"Usefulness of translesional pressure gradient and pharmacological provocation for the assessment of intermediate renal artery disease","volume":"68","author":"Jones","year":"2006","journal-title":"Catheter\u00a0Cardiovasc\u00a0Interv"},{"issue":"9","key":"10.1016\/j.acra.2023.03.033_bib25","first-page":"1851","article-title":"Assessment of renal artery stenosis severity by pressure gradient measurements","volume":"48","author":"De Bruyne","year":"2006","journal-title":"J\u00a0Am\u00a0Coll\u00a0Cardiol"},{"issue":"5","key":"10.1016\/j.acra.2023.03.033_bib26","first-page":"439","article-title":"Primary hyperaldosteronism","volume":"40","author":"Nadar","year":"2003","journal-title":"Ann\u00a0Clin\u00a0Biochem"},{"issue":"9","key":"10.1016\/j.acra.2023.03.033_bib27","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1136\/hrt.2006.107706","article-title":"Renin: friend or foe?","volume":"93","author":"Brown","year":"2007","journal-title":"Heart (Br Card Soc)"},{"issue":"6","key":"10.1016\/j.acra.2023.03.033_bib28","first-page":"410","article-title":"Use of Doppler ultrasonography to predict the outcome of therapy for renal-artery stenosis","volume":"344","author":"Radermacher","year":"2001","journal-title":"N\u00a0Engl\u00a0J\u00a0Med"},{"issue":"18","key":"10.1016\/j.acra.2023.03.033_bib29","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1161\/01.CIR.0000095786.44712.2A","article-title":"Predictors of improved renal function after percutaneous stent-supported angioplasty of severe atherosclerotic ostial renal artery stenosis","volume":"108","author":"Zeller","year":"2003","journal-title":"Circulation"},{"issue":"2, suppl","key":"10.1016\/j.acra.2023.03.033_bib30","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/j.jvir.2009.12.190","article-title":"Severity of renal artery lesions in patients enrolled into the CORAL trial","volume":"21","author":"Matsumoto","year":"2010","journal-title":"J Vasc Interv Radiol"},{"issue":"4","key":"10.1016\/j.acra.2023.03.033_bib31","first-page":"517","article-title":"Assessment of renal artery stenosis: side-by-side comparison of angiography and duplex ultrasound with pressure gradient measurements","volume":"29","author":"Drieghe","year":"2008","journal-title":"Eur\u00a0Heart J"},{"issue":"3","key":"10.1016\/j.acra.2023.03.033_bib32","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1056\/NEJMoa0807611","article-title":"Fractional flow reserve versus angiography for guiding percutaneous coronary intervention","volume":"360","author":"Tonino","year":"2009","journal-title":"N Engl J Med"},{"issue":"40","key":"10.1016\/j.acra.2023.03.033_bib33","first-page":"2831","article-title":"Evolving concepts of angiogram: fractional flow reserve discordances in 4000 coronary stenoses","volume":"35","author":"Toth","year":"2014","journal-title":"Eur\u00a0Heart J"},{"issue":"11","key":"10.1016\/j.acra.2023.03.033_bib34","first-page":"991","article-title":"Fractional flow reserve\u2013guided PCI versus medical therapy in stable coronary disease","volume":"367","author":"De Bruyne","year":"2012","journal-title":"N\u00a0Engl\u00a0J\u00a0Med"},{"issue":"13","key":"10.1016\/j.acra.2023.03.033_bib35","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1056\/NEJMoa1408758","article-title":"Fractional flow reserve\u2013guided PCI for stable coronary artery disease","volume":"371","author":"De Bruyne","year":"2014","journal-title":"N\u00a0Engl J\u00a0Med"},{"issue":"2","key":"10.1016\/j.acra.2023.03.033_bib36","first-page":"87","article-title":"2018 ESC\/EACTS guidelines on myocardial revascularization","volume":"40","author":"Neumann","year":"2019","journal-title":"Eur\u00a0Heart J"},{"issue":"3","key":"10.1016\/j.acra.2023.03.033_bib37","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0094-0143(21)00203-2","article-title":"The natural history of atherosclerotic and fibrous renal artery disease","volume":"11","author":"Schreiber","year":"1984","journal-title":"Urol Clin North Am"},{"issue":"2","key":"10.1016\/j.acra.2023.03.033_bib38","first-page":"250","article-title":"Natural history of atherosclerotic renal artery stenosis: a prospective study with duplex ultrasonography","volume":"19","author":"Zierler","year":"1994","journal-title":"J\u00a0Vasc\u00a0Surg"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633223001691?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633223001691?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T09:00:28Z","timestamp":1761037228000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633223001691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":38,"alternative-id":["S1076633223001691"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2023.03.033","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Defining Hemodynamic Significance of Renal Artery Stenosis: Insights From a Porcine Model of Graded Renal Artery Stenosis","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2023.03.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}