{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T15:27:01Z","timestamp":1774452421068,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,20]],"date-time":"2024-04-20T00:00:00Z","timestamp":1713571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","academicradiology.org","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.acra.2024.04.030","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T20:22:37Z","timestamp":1715026957000},"page":"4509-4518","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic Performance of Contrast-Enhanced Ultrasound in Testicular Space-Occupying Lesions: A Systematic Review and Meta-analysis"],"prefix":"10.1016","volume":"31","author":[{"given":"Xin","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiaoyun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liangyun","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.acra.2024.04.030_bib1","series-title":"Acute scrotum pain","author":"Velasquez","year":"2024"},{"issue":"9","key":"10.1016\/j.acra.2024.04.030_bib2","first-page":"1831","article-title":"Role of contrast enhanced ultrasound in acute scrotal diseases","volume":"21","author":"Valentino","year":"2011","journal-title":"Eur\u00a0Radiol"},{"issue":"2","key":"10.1016\/j.acra.2024.04.030_bib3","first-page":"201","article-title":"Contrast-enhanced ultrasound as a valuable imaging modality for characterizing testicular lesions","volume":"24","author":"Yu","year":"2022","journal-title":"Asian\u00a0J\u00a0Androl"},{"issue":"2","key":"10.1016\/j.acra.2024.04.030_bib4","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/JU.0000000000000318","article-title":"Diagnosis and treatment of early stage testicular cancer: AUA guideline","volume":"202","author":"Stephenson","year":"2019","journal-title":"J Urol"},{"key":"10.1016\/j.acra.2024.04.030_bib5","unstructured":"Gilligan T., Lin D.W., Aggarwal R., et al. Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology. (1540\u20131413 (Electronic))."},{"issue":"5","key":"10.1016\/j.acra.2024.04.030_bib6","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1111\/andr.13057","article-title":"Use of contrast enhanced ultrasound in testicular diseases: a\u00a0comprehensive review","volume":"9","author":"Tenuta","year":"2021","journal-title":"Andrology"},{"key":"10.1016\/j.acra.2024.04.030_bib7","unstructured":"Di Serafino M., Acampora C., Iacobellis F., et al. Ultrasound of scrotal and penile emergency: how, why and when. (1876\u20137931 (Electronic))."},{"issue":"2","key":"10.1016\/j.acra.2024.04.030_bib8","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1055\/a-0586-1107","article-title":"The EFSUMB guidelines and recommendations for the clinical practice of contrast-enhanced ultrasound (CEUS) in non-hepatic applications: update 2017 (long version)","volume":"39","author":"Sidhu","year":"2018","journal-title":"Ultraschall Med"},{"issue":"9","key":"10.1016\/j.acra.2024.04.030_bib9","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.ultrasmedbio.2006.05.031","article-title":"The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations","volume":"32","author":"Piscaglia","year":"2006","journal-title":"Ultrasound Med Biol"},{"issue":"8","key":"10.1016\/j.acra.2024.04.030_bib10","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.ultrasmedbio.2016.03.026","article-title":"Real-time elastography and contrast-enhanced ultrasonography in the evaluation of testicular masses: a comparative prospective study","volume":"42","author":"Schr\u00f6der","year":"2016","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.acra.2024.04.030_bib11","article-title":"The Application Value of Contrast-Enhanced Ultrasound in Testicular Occupied Lesions","volume":"2021","author":"Liu","year":"2021","journal-title":"Comput\u00a0Math\u00a0Methods\u00a0Med"},{"issue":"3","key":"10.1016\/j.acra.2024.04.030_bib12","first-page":"322.e1","article-title":"Qualitative and quantitative contrast-enhanced ultrasonography for the characterisation of non-palpable testicular tumours","volume":"73","author":"Luzurier","year":"2018","journal-title":"Clin\u00a0Radiol"},{"key":"10.1016\/j.acra.2024.04.030_bib13","unstructured":"McInnes MDF, Moher D., Thombs B.D., et al. Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies: The PRISMA-DTA Statement. (1538\u20133598 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib14","unstructured":"Whiting P.F., Rutjes Aw. Fau - Westwood M.E., Westwood Me. Fau - Mallett S., et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. (1539\u20133704 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib15","unstructured":"Chu H., Nie L.Fau - Chen Y., Chen Y.Fau - Huang Y., Huang Y.Fau - Sun W., Sun W. Bivariate random effects models for meta-analysis of comparative studies with binary outcomes: methods for the absolute risk difference and relative risk. (1477\u20130334 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib16","unstructured":"Irwig L., Bossuyt P.Fau - Glasziou P., Glasziou P.Fau - Gatsonis C., Gatsonis C.Fau - Lijmer J., Lijmer J. Designing studies to ensure that estimates of test accuracy are transferable. (1756\u20131833 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib17","unstructured":"Suh C.H., Park S.H. Successful Publication of Systematic Review and Meta-Analysis of Studies Evaluating Diagnostic Test Accuracy. (2005\u20138330 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib18","unstructured":"Swets J.A. Measuring the accuracy of diagnostic systems. (0036\u20138075 (Print))."},{"key":"10.1016\/j.acra.2024.04.030_bib19","unstructured":"Higgins J.P., Thompson S.G. Quantifying heterogeneity in a meta-analysis. (0277\u20136715 (Print))."},{"key":"10.1016\/j.acra.2024.04.030_bib20","unstructured":"Higgins J.P., Thompson Sg. Fau - Deeks J.J., Deeks Jj. Fau - Altman D.G., Altman D.G. Measuring inconsistency in meta-analyses. (1756\u20131833 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib21","unstructured":"Deeks J.J., Macaskill P.Fau - Irwig L., Irwig L. The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed. (0895\u20134356 (Print))."},{"key":"10.1016\/j.acra.2024.04.030_bib22","unstructured":"Wang X.S., Zhao M.Q., Zhang L., et al. Cell-free DNA in blood and urine as a diagnostic tool for bladder cancer: a meta-analysis. (1943\u20138141 (Print))."},{"key":"10.1016\/j.acra.2024.04.030_bib23","unstructured":"Chappell F.M., Raab Gm. Fau - Wardlaw J.M., Wardlaw J.M. When are summary ROC curves appropriate for diagnostic meta-analyses?; (1097\u20130258 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib24","unstructured":"Reitsma J.B., Glas As. Fau - Rutjes A.W.S., Rutjes Aw. Fau - Scholten R.J.P.M., Scholten Rj. Fau - Bossuyt P.M., Bossuyt Pm. Fau - Zwinderman A.H., Zwinderman A.H. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. (0895\u20134356 (Print))."},{"key":"10.1016\/j.acra.2024.04.030_bib25","unstructured":"Trillaud H., Bruel Jm. Fau - Valette P.-J., Valette Pj. Fau - Vilgrain V., et al. Characterization of focal liver lesions with SonoVue-enhanced sonography: international multicenter-study in comparison to CT and MRI. (2219\u20132840 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib26","doi-asserted-by":"crossref","unstructured":"Wilson S.R., Feinstein S.B. Introduction: 4th Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) in the Liver-Update 2020 WFUMB in Cooperation with EFSUMB, AFSUMB, AIUM and FLAUS. (1879\u2013291X (Electronic)).","DOI":"10.1016\/j.ultrasmedbio.2020.08.015"},{"key":"10.1016\/j.acra.2024.04.030_bib27","unstructured":"Wan Q., Cao P., Liu J.A.-O.. Meta-Analysis of Contrast Enhanced Ultrasound in Judging Benign and Malignant Thyroid Tumors. (1748\u20136718 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib28","unstructured":"Baird D.C., Meyers G.J., Hu J.S. Testicular Cancer: Diagnosis and Treatment. (1532\u20130650 (Electronic))."},{"key":"10.1016\/j.acra.2024.04.030_bib29","unstructured":"Djaladat H., Burner E., Parikh P.M., Beroukhim Kay D., Hays K. The Association Between Testis Cancer and Semen Abnormalities Before Orchiectomy: A Systematic Review. (2156\u2013535X (Electronic))."},{"issue":"2","key":"10.1016\/j.acra.2024.04.030_bib30","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1148\/radiol.14132718","article-title":"Differential diagnosis of nonpalpable testicular lesions: qualitative and quantitative contrast-enhanced US of benign and malignant testicular tumors","volume":"273","author":"Isidori","year":"2014","journal-title":"Radiology"},{"issue":"5","key":"10.1016\/j.acra.2024.04.030_bib31","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.purol.2015.01.007","article-title":"Testicular nodules of infertile men and contrast enhanced ultrasonography: preliminary study","volume":"25","author":"Vandaele","year":"2015","journal-title":"Prog Urol"},{"issue":"2","key":"10.1016\/j.acra.2024.04.030_bib32","first-page":"347","article-title":"Diagnostic performance of contrast-enhanced ultrasound (CEUS) in testicular pathologies: Single-center results","volume":"73","author":"Lerchbaumer","year":"2019","journal-title":"Clin\u00a0Hemorheol\u00a0Microcirc"},{"issue":"2","key":"10.1016\/j.acra.2024.04.030_bib33","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1148\/radiol.2017161373","article-title":"Value of multiparametric US in the assessment of intratesticular lesions","volume":"285","author":"Auer","year":"2017","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.acra.2024.04.030_bib34","doi-asserted-by":"crossref","first-page":"50","DOI":"10.4103\/aja202235","article-title":"Multiparametric ultrasound for the assessment of testicular lesions with negative tumoral markers","volume":"25","author":"Liu","year":"2022","journal-title":"Asian J\u00a0Androl"},{"issue":"3","key":"10.1016\/j.acra.2024.04.030_bib35","first-page":"241","article-title":"Multiparametric ultrasonographic analysis of testicular tumors: a single-center experience in a collective of 49 patients","volume":"54","author":"Schwarze","year":"2020","journal-title":"Scand\u00a0J\u00a0Urol"},{"issue":"7","key":"10.1016\/j.acra.2024.04.030_bib36","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1111\/andr.13233","article-title":"Multiparametric ultrasound for the diagnosis of Leydig cell tumours in non-palpable testicular lesions","volume":"10","author":"Corcioni","year":"2022","journal-title":"Andrology"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633224002393?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633224002393?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T16:01:20Z","timestamp":1730390480000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633224002393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":36,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["S1076633224002393"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2024.04.030","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic Performance of Contrast-Enhanced Ultrasound in Testicular Space-Occupying Lesions: A Systematic Review and Meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2024.04.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Association of University Radiologists. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}