{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:50:52Z","timestamp":1787503852636,"version":"build-2736575974"},"reference-count":30,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007194","name":"Wenzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["Y20220269"],"award-info":[{"award-number":["Y20220269"]}],"id":[{"id":"10.13039\/501100007194","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82100952"],"award-info":[{"award-number":["82100952"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071902"],"award-info":[{"award-number":["82071902"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.acra.2024.05.009","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T23:26:03Z","timestamp":1716593163000},"page":"3783-3792","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Pituitary MRI Radiomics Improves Diagnostic Performance of Growth Hormone Deficiency in Children Short Stature: A\u00a0Multicenter Radiomics Study"],"prefix":"10.1016","volume":"31","author":[{"given":"Kun","family":"Shu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keren","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruifang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zirui","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihan","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.acra.2024.05.009_bib1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1136\/archdischild-2014-307228","article-title":"Controversies in the diagnosis and management of growth hormone deficiency in childhood and adolescence","volume":"101","author":"Murray","year":"2016","journal-title":"Arch Dis Child"},{"issue":"10","key":"10.1016\/j.acra.2024.05.009_bib2","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/s41574-021-00539-5","article-title":"Advances in differential diagnosis and management of growth hormone deficiency in children","volume":"17","author":"Hage","year":"2021","journal-title":"Nat Rev Endocrinol"},{"issue":"2","key":"10.1016\/j.acra.2024.05.009_bib3","doi-asserted-by":"crossref","DOI":"10.1001\/jamapediatrics.2020.5199","article-title":"Association of childhood growth hormone treatment with long-term cardiovascular morbidity","volume":"175","author":"Tidblad","year":"2021","journal-title":"JAMA Pediatr"},{"issue":"2","key":"10.1016\/j.acra.2024.05.009_bib4","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1210\/jc.2011-1995","article-title":"Long-term mortality after recombinant growth hormone treatment for isolated growth hormone deficiency or childhood short stature: preliminary report of the French SAGhE study","volume":"97","author":"Carel","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"10.1016\/j.acra.2024.05.009_bib5","doi-asserted-by":"crossref","first-page":"856","DOI":"10.3349\/ymj.2022.63.9.856","article-title":"A radiomics-based model with the potential to differentiate growth hormone deficiency and idiopathic short stature on sella MRI","volume":"63","author":"Lee","year":"2022","journal-title":"Yonsei Med J"},{"issue":"2","key":"10.1016\/j.acra.2024.05.009_bib6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3892\/etm.2014.1778","article-title":"Three-dimensional magnetic resonance volumetry of the pituitary gland is effective in detecting short stature in children","volume":"8","author":"Han","year":"2014","journal-title":"Exp Ther Med"},{"issue":"10","key":"10.1016\/j.acra.2024.05.009_bib7","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1515\/jpem-2015-0404","article-title":"Pituitary volume in children with growth hormone deficiency, idiopathic short stature and controls","volume":"29","author":"Kessler","year":"2016","journal-title":"J Pediatr Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.acra.2024.05.009_bib8","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.ejca.2011.11.036","article-title":"Radiomics: extracting more information from medical images using advanced feature analysis","volume":"48","author":"Lambin","year":"2012","journal-title":"Eur J Cancer"},{"issue":"18","key":"10.1016\/j.acra.2024.05.009_bib9","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1200\/JCO.2015.65.9128","article-title":"Development and validation of a radiomics nomogram for preoperative prediction of lymph node metastasis in colorectal cancer","volume":"34","author":"Huang","year":"2016","journal-title":"J Clin Oncol"},{"issue":"3","key":"10.1016\/j.acra.2024.05.009_bib10","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1093\/brain\/awab340","article-title":"An MRI radiomics approach to predict survival and tumour-infiltrating macrophages in gliomas","volume":"145","author":"Li","year":"2022","journal-title":"Brain"},{"key":"10.1016\/j.acra.2024.05.009_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103460","article-title":"Magnetic resonance imaging radiomics predicts preoperative axillary lymph node metastasis to support surgical decisions and is associated with tumor microenvironment in invasive breast cancer: A machine learning, multicenter study","volume":"69","author":"Yu","year":"2021","journal-title":"EBioMedicine"},{"key":"10.1016\/j.acra.2024.05.009_bib12","doi-asserted-by":"crossref","first-page":"4006","DOI":"10.1038\/ncomms5006","article-title":"Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach","volume":"5","author":"Aerts","year":"2014","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.acra.2024.05.009_bib13","article-title":"MRI-based quantification of intratumoral heterogeneity for predicting treatment response to neoadjuvant chemotherapy in breast cancer","volume":"308","author":"Shi","year":"2023","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.acra.2024.05.009_bib14","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1007\/s00330-018-5725-3","article-title":"Preoperative prediction of cavernous sinus invasion by pituitary adenomas using a radiomics method based on magnetic resonance images","volume":"29","author":"Niu","year":"2019","journal-title":"Eur Radiol"},{"key":"10.1016\/j.acra.2024.05.009_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2020.103966","article-title":"MRI radiomics for the prediction of recurrence in patients with clinically non-functioning pituitary macroadenomas","volume":"124","author":"Machado","year":"2020","journal-title":"Comput Biol Med"},{"issue":"6","key":"10.1016\/j.acra.2024.05.009_bib16","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s11102-020-01077-5","article-title":"Radiomics model predicts granulation pattern in growth hormone-secreting pituitary adenomas","volume":"23","author":"Park","year":"2020","journal-title":"Pituitary"},{"issue":"6","key":"10.1016\/j.acra.2024.05.009_bib17","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1002\/jmri.28709","article-title":"Development and validation of a combined MRI radiomics, imaging and clinical parameter-based machine learning model for identifying idiopathic central precocious puberty in girls","volume":"58","author":"Zou","year":"2023","journal-title":"J Magn Reson Imaging"},{"issue":"5","key":"10.1016\/j.acra.2024.05.009_bib18","doi-asserted-by":"crossref","first-page":"494","DOI":"10.3892\/etm.2021.9925","article-title":"Development of a predictive model of growth hormone deficiency and idiopathic short stature in children","volume":"21","author":"Cong","year":"2021","journal-title":"Exp Ther Med"},{"issue":"9","key":"10.1016\/j.acra.2024.05.009_bib19","doi-asserted-by":"crossref","first-page":"e267","DOI":"10.1016\/j.acra.2020.05.004","article-title":"Hybrid clinical-radiomics model for precisely predicting the invasiveness of lung adenocarcinoma manifesting as pure ground-glass nodule","volume":"28","author":"Song","year":"2021","journal-title":"Acad Radiol"},{"issue":"12","key":"10.1016\/j.acra.2024.05.009_bib20","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.45141","article-title":"Computed tomographic radiomics in differentiating histologic subtypes of epithelial ovarian carcinoma","volume":"5","author":"Wang","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"11","key":"10.1016\/j.acra.2024.05.009_bib21","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1210\/jc.2008-0509","article-title":"Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop","volume":"93","author":"Cohen","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"10.1016\/j.acra.2024.05.009_bib22","first-page":"3990","article-title":"Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: summary statement of the GH Research Society. GH Research Society","volume":"85","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.acra.2024.05.009_bib23","first-page":"361","article-title":"Craniocerebral imaging in children with short stature","volume":"10","author":"Barros","year":"1997","journal-title":"Acta Med Port"},{"issue":"5","key":"10.1016\/j.acra.2024.05.009_bib24","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.3390\/s21051846","article-title":"Maximum relevance minimum redundancy dropout with informative kernel determinantal point process","volume":"21","author":"Saffari","year":"2021","journal-title":"Sensors (Basel)"},{"issue":"3","key":"10.1016\/j.acra.2024.05.009_bib25","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/neuonc\/noy133","article-title":"Incorporating diffusion- and perfusion-weighted MRI into a radiomics model improves diagnostic performance for pseudoprogression in glioblastoma patients","volume":"21","author":"Kim","year":"2019","journal-title":"Neuro Oncol"},{"issue":"11","key":"10.1016\/j.acra.2024.05.009_bib26","doi-asserted-by":"crossref","first-page":"7609","DOI":"10.1007\/s00330-023-09727-5","article-title":"Prediction of Ki-67 expression in gastrointestinal stromal tumors using radiomics of plain and multiphase contrast-enhanced CT","volume":"33","author":"Liu","year":"2023","journal-title":"Eur Radiol"},{"issue":"1","key":"10.1016\/j.acra.2024.05.009_bib27","first-page":"1","article-title":"Growth hormone deficiency: an update","volume":"38","author":"Aud\u00ed","year":"2013","journal-title":"Minerva Endocrinol"},{"issue":"2","key":"10.1016\/j.acra.2024.05.009_bib28","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1210\/er.2008-0027","article-title":"Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects","volume":"30","author":"M\u00f8ller","year":"2009","journal-title":"Endocr Rev"},{"issue":"4","key":"10.1016\/j.acra.2024.05.009_bib29","doi-asserted-by":"crossref","DOI":"10.1210\/jendso\/bvad018","article-title":"Diagnostic value of IGF-1 in growth hormone-deficient children: is a second growth hormone stimulation test necessary?","volume":"7","author":"Fatani","year":"2023","journal-title":"J Endocr Soc"},{"issue":"4","key":"10.1016\/j.acra.2024.05.009_bib30","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1365-2265.1993.tb02389.x","article-title":"Plasma IGFBP-3 and its relationship with quantitative growth hormone secretion in short children","volume":"39","author":"Phillip","year":"1993","journal-title":"Clin Endocrinol (Oxf)"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633224002939?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633224002939?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T12:14:33Z","timestamp":1778588073000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633224002939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":30,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S1076633224002939"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2024.05.009","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pituitary MRI Radiomics Improves Diagnostic Performance of Growth Hormone Deficiency in Children Short Stature: A\u00a0Multicenter Radiomics Study","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2024.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Association of University Radiologists. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}