{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:55:37Z","timestamp":1792180537899,"version":"4.4.0"},"reference-count":70,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T00:00:00Z","timestamp":1748131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171987"],"award-info":[{"award-number":["82171987"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82402333"],"award-info":[{"award-number":["82402333"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018617","name":"Liaoning Revitalization Talents Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018617","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007620","name":"Department of Education of Liaoning Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007620","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Liaoning Provincial Science and Technology Program Joint Plan Project","award":["2024-MSLH-547"],"award-info":[{"award-number":["2024-MSLH-547"]}]},{"name":"Basic science project of the educational department of Liaoning province","award":["LJ232410159018"],"award-info":[{"award-number":["LJ232410159018"]}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.acra.2025.05.053","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T01:08:55Z","timestamp":1749690535000},"page":"6857-6872","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Head-to-head Comparison of [68Ga]Ga-FAPI-04 PET and [18F]FDG PET in the Evaluation of Primary Gastrointestinal Tumors and Metastases: A Systematic Review and Meta-analysis"],"prefix":"10.1016","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7227-1036","authenticated-orcid":false,"given":"Yuxuan","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bulin","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingqi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiani","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1109-0980","authenticated-orcid":false,"given":"Xuena","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib1","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1053\/j.gastro.2020.02.068","article-title":"Global burden of 5 major types of gastrointestinal cancer","volume":"159","author":"Arnold","year":"2020","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib3","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1001\/jamaoncol.2021.6987","article-title":"Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"8","author":"Global Burden of Disease 2019 Cancer Collaboration","year":"2022","journal-title":"JAMA Oncol"},{"issue":"Pt 2","key":"10.1016\/j.acra.2025.05.053_bib4","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.semcancer.2022.04.009","article-title":"Emerging role of nanoparticles in the diagnostic imaging of gastrointestinal cancer","volume":"86","author":"Zhou","year":"2022","journal-title":"Semin Cancer Biol"},{"issue":"7","key":"10.1016\/j.acra.2025.05.053_bib5","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1001\/jama.2021.0106","article-title":"Diagnosis and treatment of metastatic colorectal cancer: a review","volume":"325","author":"Biller","year":"2021","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib6","first-page":"333","article-title":"Molecular imaging in oncology: Current impact and future directions","volume":"72","author":"Rowe","year":"2022","journal-title":"CA Cancer J Clin"},{"issue":"5","key":"10.1016\/j.acra.2025.05.053_bib7","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1093\/rheumatology\/keab675","article-title":"2-deoxy-2[18F]fluoro-D-glucose positron emission tomography-computed tomography in rheumatological diseases","volume":"61","author":"Subesinghe","year":"2022","journal-title":"Rheumatol Oxf Engl"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10120-011-0017-5","article-title":"Japanese gastric cancer association task force for research promotion: clinical utility of 18F-fluoro-2-deoxyglucose positron emission tomography in gastric cancer. A systematic review of the literature","volume":"14","author":"Shimada","year":"2011","journal-title":"Gastric Cancer"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib9","doi-asserted-by":"crossref","first-page":"43S","DOI":"10.2967\/jnumed.108.057224","article-title":"Monitoring and predicting response to therapy with 18 F-FDG PET in colorectal cancer: a systematic review","volume":"50","author":"De Geus-Oei","year":"2009","journal-title":"J Nucl Med"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib10","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1007\/s00330-022-09084-9","article-title":"Comparison of [68Ga]Ga-FAPI and [18F]FDG uptake in patients with gastric signet-ring-cell carcinoma: a multicenter retrospective study","volume":"33","author":"Chen","year":"2022","journal-title":"Eur Radiol"},{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib11","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1097\/RLU.0000000000005024","article-title":"Comparison of 18 F-FDG and 18 F-FAPI PET\/CT findings of signet-ring cell carcinoma of the stomach","volume":"49","author":"Zhao","year":"2024","journal-title":"Clin Nucl Med"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib12","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00261-019-02268-w","article-title":"Can [18F]F-FDG PET\/CT be used to assess the pre-operative extent of peritoneal carcinomatosis in patients with colorectal cancer?","volume":"45","author":"Elekonawo","year":"2020","journal-title":"Abdom Radiol N Y"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib13","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/s41573-018-0004-1","article-title":"Turning foes to friends: targeting cancer-associated fibroblasts","volume":"18","author":"Chen","year":"2019","journal-title":"Nat Rev Drug Discov"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib14","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12943-023-01860-5","article-title":"Define cancer-associated fibroblasts (CAFs) in the tumor microenvironment: new opportunities in cancer immunotherapy and advances in clinical trials","volume":"22","author":"Zhang","year":"2023","journal-title":"Mol Cancer"},{"issue":"13","key":"10.1016\/j.acra.2025.05.053_bib15","doi-asserted-by":"crossref","first-page":"5778","DOI":"10.7150\/thno.41409","article-title":"Design and validation of fibroblast activation protein alpha targeted imaging and therapeutic agents","volume":"10","author":"Roy","year":"2020","journal-title":"Theranostics"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib16","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/ijc.32193","article-title":"In search of definitions: cancer-associated fibroblasts and their markers","volume":"146","author":"Nurmik","year":"2020","journal-title":"Int J Cancer"},{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib17","doi-asserted-by":"crossref","first-page":"123","DOI":"10.4161\/cbt.13.3.18696","article-title":"Fibroblast activation protein: a potential therapeutic target in cancer","volume":"13","author":"Liu","year":"2012","journal-title":"Cancer Biol Ther"},{"issue":"9","key":"10.1016\/j.acra.2025.05.053_bib18","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.2967\/jnumed.118.210435","article-title":"A tumor-imaging method targeting cancer-associated fibroblasts","volume":"59","author":"Loktev","year":"2018","journal-title":"J Nucl Med"},{"issue":"8","key":"10.1016\/j.acra.2025.05.053_bib19","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1007\/s00259-020-04769-z","article-title":"Comparison of [68Ga]ga-DOTA-FAPI-04 and [18F] FDG PET\/CT for the diagnosis of primary and metastatic lesions in patients with various types of cancer","volume":"47","author":"Chen","year":"2020","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib20","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.dld.2021.07.011","article-title":"FAPI PET\/CT research progress in digestive system tumours","volume":"54","author":"Peng","year":"2022","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.acra.2025.05.053_bib21","article-title":"FAPI PET\/CT in the diagnosis of abdominal and pelvic tumors","volume":"11","author":"Yang","year":"2021","journal-title":"Front Oncol"},{"issue":"7","key":"10.1016\/j.acra.2025.05.053_bib22","doi-asserted-by":"crossref","first-page":"e509","DOI":"10.1097\/RLU.0000000000004166","article-title":"Perirenal infiltration of signet ring cell colon carcinoma shown by 68Ga-FAPI PET\/CT","volume":"47","author":"G\u00fczel","year":"2022","journal-title":"Clin Nucl Med"},{"issue":"5","key":"10.1016\/j.acra.2025.05.053_bib23","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1007\/s00259-020-05155-5","article-title":"68Ga]ga-FAPI-04 PET\/CT imaging in signet-ring cell carcinoma of sigmoid colon","volume":"48","author":"Fu","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib24","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1097\/MNM.0000000000001489","article-title":"Comparison of 18F-FDG PET\/CT and 68Ga-FAPI-04 PET\/CT in the staging and restaging of gastric adenocarcinoma","volume":"43","author":"G\u00fcndo\u011fan","year":"2022","journal-title":"Nucl Med Commun"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib25","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1148\/radiol.2020203275","article-title":"Comparison of 68 ga-FAPI and 18 F-FDG uptake in gastric, duodenal, and colorectal cancers","volume":"298","author":"Pang","year":"2021","journal-title":"Radiology"},{"issue":"7","key":"10.1016\/j.acra.2025.05.053_bib26","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.2967\/jnumed.123.265594","article-title":"Fibroblast activation protein inhibitor\u2013based radionuclide therapies: current status and future directions","volume":"64","author":"Ora","year":"2023","journal-title":"J Nucl Med"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib27","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s40644-023-00598-z","article-title":"FAP-targeted PET imaging in gastrointestinal malignancies: a comprehensive review","volume":"23","author":"Ar\u00e7ay \u00d6zt\u00fcrk","year":"2023","journal-title":"Cancer Imaging"},{"key":"10.1016\/j.acra.2025.05.053_bib28","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib29","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1148\/radiol.2018171356","article-title":"Effects of tumor burden on reference tissue standardized uptake for PET imaging: modification of PERCIST criteria","volume":"287","author":"Viglianti","year":"2018","journal-title":"Radiology"},{"issue":"8","key":"10.1016\/j.acra.2025.05.053_bib30","doi-asserted-by":"crossref","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","article-title":"QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies","volume":"155","author":"Whiting","year":"2011","journal-title":"Ann Intern Med"},{"issue":"11","key":"10.1016\/j.acra.2025.05.053_bib31","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.acra.2025.05.053_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.1087792","article-title":"Diagnostic value of [68Ga]ga-FAPI-04 in patients with colorectal cancer in comparison with [18F]F-FDG PET\/CT","volume":"12","author":"Lin","year":"2023","journal-title":"Front Oncol"},{"key":"10.1016\/j.acra.2025.05.053_bib33","article-title":"Comparison of diagnostic efficacy of [68Ga]ga-FAPI-04 and [18F]FDG PET\/CT for staging and restaging of gastric cancer","volume":"12","author":"Zhang","year":"2022","journal-title":"Front Oncol"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib34","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1007\/s00259-021-05441-w","article-title":"Comparison of [68 ga]ga-FAPI-04 and [18F]-FDG for the detection of primary and metastatic lesions in patients with gastric cancer: a bicentric retrospective study","volume":"49","author":"Jiang","year":"2022","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib35","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1007\/s00259-021-05494-x","article-title":"Head-to-head comparison of [68Ga]ga-FAPI-04 and [18F]-FDG PET\/CT in evaluating the extent of disease in gastric adenocarcinoma","volume":"49","author":"Kuten","year":"2022","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib36","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2967\/jnumed.120.258467","article-title":"68 ga-DOTA-FAPI-04 PET\/MR in the evaluation of gastric carcinomas: comparison with 18 F-FDG PET\/CT","volume":"63","author":"Qin","year":"2022","journal-title":"J Nucl Med"},{"issue":"8","key":"10.1016\/j.acra.2025.05.053_bib37","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1007\/s00259-022-05799-5","article-title":"68Ga]Ga-DOTA-FAPI-04 PET\/CT in the evaluation of gastric cancer: comparison with [18F]FDG PET\/CT","volume":"49","author":"Lin","year":"2022","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"11","key":"10.1016\/j.acra.2025.05.053_bib38","doi-asserted-by":"crossref","first-page":"3898","DOI":"10.1007\/s00259-022-05839-0","article-title":"Comparison of [68 Ga]Ga-DOTA-FAPI-04 PET\/CT and [18F]FDG PET\/CT in colorectal cancer","volume":"49","author":"K\u00f6mek","year":"2022","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.acra.2025.05.053_bib39","first-page":"6351330","article-title":"Comparison of [68Ga]Ga-DOTA-FAPI-04 and [18F]FDG PET\/MRI in the Preoperative Diagnosis of Gastric Cancer","volume":"2023","author":"Du","year":"2023"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib40","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1007\/s00330-022-09251-y","article-title":"Usefulness of [68Ga]FAPI-04 and [18F]FDG PET\/CT for the detection of primary tumour and metastatic lesions in gastrointestinal carcinoma: a comparative study","volume":"33","author":"Li","year":"2022","journal-title":"Eur Radiol"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib41","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/RLU.0000000000004604","article-title":"Comparison of 18F-FDG and 68Ga-FAPI-04 uptake in postoperative re-evaluation of gastric, duodenal, and colorectal cancers","volume":"48","author":"Liu","year":"2023","journal-title":"Clin Nucl Med"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib42","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/MNM.0000000000001661","article-title":"Diagnostic performance of Ga-68 FAPI 04 PET\/CT in colorectal malignancies","volume":"44","author":"Prashanth","year":"2023","journal-title":"Nucl Med Commun"},{"issue":"6","key":"10.1016\/j.acra.2025.05.053_bib43","doi-asserted-by":"crossref","first-page":"4355","DOI":"10.1007\/s00330-022-09321-1","article-title":"Utility of [68Ga]FAPI-04 and [18F]FDG dual-tracer PET\/CT in the initial evaluation of gastric cancer","volume":"33","author":"Miao","year":"2022","journal-title":"Eur Radiol"},{"issue":"11","key":"10.1016\/j.acra.2025.05.053_bib44","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1097\/MNM.0000000000001751","article-title":"PET\/CT imaging fibroblast activation protein in initial colorectal cancer: compared to 18F-FDG PET\/CT","volume":"44","author":"Dong","year":"2023","journal-title":"Nucl Med Commun"},{"issue":"6","key":"10.1016\/j.acra.2025.05.053_bib45","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/nrgastro.2017.33","article-title":"Molecular subtypes in cancers of the gastrointestinal tract","volume":"14","author":"Bijlsma","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"16","key":"10.1016\/j.acra.2025.05.053_bib46","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1200\/JCO.2014.60.2847","article-title":"Use of imaging for GI cancers","volume":"33","author":"Bentley-Hibbert","year":"2015","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib47","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s10120-016-0669-2","article-title":"Intratumor stromal proportion predicts aggressive phenotype of gastric signet ring cell carcinomas","volume":"20","author":"Lee","year":"2017","journal-title":"Gastric Cancer"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib48","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1007\/s00259-002-1029-5","article-title":"FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings","volume":"30","author":"Stahl","year":"2003","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"20","key":"10.1016\/j.acra.2025.05.053_bib49","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000000864","article-title":"18F-FDG PET\/CT role in staging of gastric carcinomas: comparison with conventional contrast enhancement computed tomography","volume":"94","author":"Altini","year":"2015","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"10.1016\/j.acra.2025.05.053_bib50","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/s11307-022-01729-x","article-title":"Comparison of 68Ga-FAPI PET\/CT and 18FDG PET\/CT Modalities in Gastrointestinal System Malignancies with Peritoneal Involvement","volume":"24","author":"Elboga","year":"2022","journal-title":"Mol Imaging Biol"},{"key":"10.1016\/j.acra.2025.05.053_bib51","doi-asserted-by":"crossref","DOI":"10.2967\/jnumed.123.267260","article-title":"A systematic review on the diagnostic value of fibroblast activation protein inhibitor PET\/CT in genitourinary cancers","author":"Hagens","year":"2024","journal-title":"J Nucl Med"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib52","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s40001-023-00997-9","article-title":"68Ga]Ga-FAPI-04 PET MRI\/CT in the evaluation of gastric carcinomas compared with [18F]-FDG PET MRI\/CT: a meta-analysis","volume":"28","author":"Wang","year":"2023","journal-title":"Eur J Med Res"},{"key":"10.1016\/j.acra.2025.05.053_bib53","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1202505","article-title":"Head-to-head comparison of 68Ga-FAPI-04 PET\/CT and 18F-FDG PET\/CT in the evaluation of primary digestive system cancer: a systematic review and meta-analysis","volume":"13","author":"Ouyang","year":"2023","journal-title":"Front Oncol"},{"issue":"13","key":"10.1016\/j.acra.2025.05.053_bib54","doi-asserted-by":"crossref","first-page":"4694","DOI":"10.7150\/thno.88335","article-title":"Evaluation of FAPI PET imaging in gastric cancer: a systematic review and meta-analysis","volume":"13","author":"Ruan","year":"2023","journal-title":"Theranostics"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib55","first-page":"35","article-title":"Head to head comparison of 68Ga-FAPI PET\/CT with 18F-FDG PET\/CT in primary and metastatic lesions of gastric tumor: a systematic review and meta-analysis","volume":"27","author":"Gao","year":"2024","journal-title":"Hell J Nucl Med"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib56","doi-asserted-by":"crossref","first-page":"527","DOI":"10.2967\/jnumed.123.266806","article-title":"68Ga-FAPI-04 PET\/CT in non\u2013small cell lung cancer: accurate evaluation of lymph node metastasis and correlation with fibroblast activation protein expression","volume":"65","author":"Li","year":"2024","journal-title":"J Nucl Med"},{"issue":"5","key":"10.1016\/j.acra.2025.05.053_bib57","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1007\/s00330-018-5904-2","article-title":"Routinely staging gastric cancer with 18F-FDG PET-CT detects additional metastases and predicts early recurrence and death after surgery","volume":"29","author":"Findlay","year":"2019","journal-title":"Eur Radiol"},{"issue":"2","key":"10.1016\/j.acra.2025.05.053_bib58","doi-asserted-by":"crossref","first-page":"e78","DOI":"10.1097\/RLU.0000000000003245","article-title":"Widespread metastatic gastric signet-ring cell carcinoma shown by 68Ga-FAPI PET\/CT","volume":"46","author":"Fan","year":"2021","journal-title":"Clin Nucl Med"},{"issue":"13","key":"10.1016\/j.acra.2025.05.053_bib59","doi-asserted-by":"crossref","first-page":"4523","DOI":"10.1007\/s00259-021-05213-6","article-title":"68Ga]DOTA-FAPI-04 PET\/CT imaging in a case of a signet ring cell carcinoma of stomach","volume":"48","author":"Alan-Sel\u00e7uk","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib60","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/1097-0142(20010801)92:3<634::AID-CNCR1364>3.0.CO;2-X","article-title":"Expression of glucose transporter-1 in human gastric carcinoma: association with tumor aggressiveness, metastasis, and patient survival","volume":"92","author":"Kawamura","year":"2001","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib61","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s10120-013-0234-1","article-title":"Clinicopathological characteristics and prognosis of signet ring cell carcinoma of the stomach","volume":"17","author":"Kwon","year":"2014","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.acra.2025.05.053_bib62","doi-asserted-by":"crossref","DOI":"10.1007\/s00261-024-04266-z","article-title":"Head-to-head comparison of the diagnostic performance between 68Ga-FAPI-04 PET\/CT and 18F-FDG PET\/CT in colorectal cancer: a systematic review and meta-analysis","author":"Zhuang","year":"2024","journal-title":"Abdom Radiol N Y"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib63","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s00259-003-1330-y","article-title":"Positron flight in human tissues and its influence on PET image spatial resolution","volume":"31","author":"S\u00e1nchez-Crespo","year":"2004","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"10","key":"10.1016\/j.acra.2025.05.053_bib64","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1084\/jem.20181705","article-title":"Embryonic FAP+ lymphoid tissue organizer cells generate the reticular network of adult lymph nodes","volume":"216","author":"Denton","year":"2019","journal-title":"J Exp Med"},{"issue":"1","key":"10.1016\/j.acra.2025.05.053_bib65","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00259-020-04940-6","article-title":"Usefulness of [68Ga]Ga-DOTA-FAPI-04 PET\/CT in patients presenting with inconclusive [18F]FDG PET\/CT findings","volume":"48","author":"Chen","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib66","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.2020202469","article-title":"68Ga FAPI PET\/CT imaging in peritoneal carcinomatosis","volume":"297","author":"Guo","year":"2020","journal-title":"Radiology"},{"issue":"5","key":"10.1016\/j.acra.2025.05.053_bib67","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/s41575-019-0115-0","article-title":"Cancer-associated fibroblasts in gastrointestinal cancer","volume":"16","author":"Kobayashi","year":"2019","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"4","key":"10.1016\/j.acra.2025.05.053_bib68","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1007\/s00261-020-02447-0","article-title":"Clinical impact of FDG PET\/CT in alimentary tract malignancies: an updated review","volume":"45","author":"Akin","year":"2020","journal-title":"Abdom Radiol N Y"},{"issue":"3","key":"10.1016\/j.acra.2025.05.053_bib69","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1007\/s00259-022-06021-2","article-title":"68Ga]Ga-FAPI PET for the evaluation of digestive system tumors: systematic review and meta-analysis","volume":"50","author":"Huang","year":"2023","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"12","key":"10.1016\/j.acra.2025.05.053_bib70","doi-asserted-by":"crossref","first-page":"10136","DOI":"10.3390\/ijms241210136","article-title":"Diagnostic performance of positron emission tomography with fibroblast-activating protein inhibitors in gastric cancer: a systematic review and meta-analysis","volume":"24","author":"Rizzo","year":"2023","journal-title":"Int J Mol Sci"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633225005306?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633225005306?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T16:20:28Z","timestamp":1763742028000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633225005306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":70,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S1076633225005306"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2025.05.053","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Head-to-head Comparison of [68Ga]Ga-FAPI-04 PET and [18F]FDG PET in the Evaluation of Primary Gastrointestinal Tumors and Metastases: A Systematic Review and Meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2025.05.053","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Association of Academic Radiology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}