{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:42:59Z","timestamp":1787859779810,"version":"build-2784847793"},"reference-count":58,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA191207"],"award-info":[{"award-number":["R01CA191207"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA277037"],"award-info":[{"award-number":["R01CA277037"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007928","name":"University of Pennsylvania Perelman School of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007928","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Institutes of Health National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA155348"],"award-info":[{"award-number":["R01CA155348"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.acra.2025.11.014","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T05:07:46Z","timestamp":1766120866000},"page":"1735-1747","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Optical Redox Imaging of Breast Cancer NADH Redox Status Associated with PGC1\u03b1 Gene Expression"],"prefix":"10.1016","volume":"33","author":[{"given":"Zhenwu","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He N.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenbo","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony R.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Floros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Mach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9447-7982","authenticated-orcid":false,"given":"Lin Z.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.acra.2025.11.014_bib1","first-page":"7508","article-title":"Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism","volume":"293","author":"Goodman","year":"2018","journal-title":"J\u00a0Biol\u00a0Chem"},{"key":"10.1016\/j.acra.2025.11.014_bib2","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1089\/ars.2017.7479","article-title":"Signaling and regulation through the NAD(+) and NADP(+) networks","volume":"30","author":"Hassinen","year":"2019","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.acra.2025.11.014_bib3","first-page":"645","article-title":"Imaging mitochondrial redox potential and its possible link to tumor metastatic potential","volume":"44","author":"Li","year":"2012","journal-title":"J\u00a0Bioenerg\u00a0Biomembr"},{"key":"10.1016\/j.acra.2025.11.014_bib4","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1142\/S1793545809000735","article-title":"Mitochondrial redox imaging for cancer diagnostic and therapeutic studies","volume":"2","author":"Li","year":"2009","journal-title":"J Innov Opt Heal Sci"},{"key":"10.1016\/j.acra.2025.11.014_bib5","first-page":"413","article-title":"Label-free optical metabolic imaging in cells and tissues","volume":"25","author":"Georgakoudi","year":"2023","journal-title":"Ann\u00a0Rev\u00a0Biomed\u00a0Eng"},{"key":"10.1016\/j.acra.2025.11.014_bib6","article-title":"Quantitative redox imaging biomarkers for studying tissue metabolic state and its heterogeneity","volume":"7","author":"Xu","year":"2014","journal-title":"J Innov Opt Heal Sci"},{"key":"10.1016\/j.acra.2025.11.014_bib7","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1089\/ars.2017.7451","article-title":"Evaluating cell metabolism through autofluorescence imaging of NAD(P)H and FAD","volume":"30","author":"Kolenc","year":"2019","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.acra.2025.11.014_bib8","doi-asserted-by":"crossref","first-page":"S23901","DOI":"10.1117\/1.JBO.30.S2.S23901","article-title":"Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling","volume":"30","author":"Georgakoudi","year":"2025","journal-title":"J Biomed Opt"},{"key":"10.1016\/j.acra.2025.11.014_bib9","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1158\/0008-5472.CAN-13-2713","article-title":"Endogenous two-photon fluorescence imaging elucidates metabolic changes related to enhanced glycolysis and glutamine consumption in precancerous epithelial tissues","volume":"74","author":"Varone","year":"2014","journal-title":"Cancer Res"},{"key":"10.1016\/j.acra.2025.11.014_bib10","doi-asserted-by":"crossref","first-page":"3432","DOI":"10.1038\/srep03432","article-title":"Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation","volume":"3","author":"Quinn","year":"2013","journal-title":"Sci Rep"},{"key":"10.1016\/j.acra.2025.11.014_bib11","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/2193-1801-2-73","article-title":"Characterizing the metabolic heterogeneity in human breast cancer xenografts by 3D high resolution fluorescence imaging","volume":"2","author":"Xu","year":"2013","journal-title":"SpringerPlus"},{"key":"10.1016\/j.acra.2025.11.014_bib12","first-page":"6608","article-title":"Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential","volume":"106","author":"Li","year":"2009","journal-title":"Proc\u00a0Natl Acad\u00a0Sci\u00a0USA"},{"key":"10.1016\/j.acra.2025.11.014_bib13","article-title":"Quantitative mitochondrial redox imaging of breast cancer metastatic potential","volume":"15","author":"Xu","year":"2010","journal-title":"J\u00a0Biomed\u00a0Opt"},{"key":"10.1016\/j.acra.2025.11.014_bib14","article-title":"Redox imaging of the p53-dependent mitochondrial redox state in colon cancer ex vivo","volume":"6","author":"Xu","year":"2013","journal-title":"J Innov Opt Heal Sci"},{"key":"10.1016\/j.acra.2025.11.014_bib15","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.21.11.114003","article-title":"Optical redox imaging indices discriminate human breast cancer from normal tissues","volume":"21","author":"Xu","year":"2016","journal-title":"J Biomed Opt"},{"key":"10.1016\/j.acra.2025.11.014_bib16","first-page":"343","article-title":"Imaging the redox states of human breast cancer core biopsies","volume":"765","author":"Xu","year":"2013","journal-title":"Adv\u00a0Exp\u00a0Med\u00a0Biol"},{"key":"10.1016\/j.acra.2025.11.014_bib17","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.acra.2013.02.006","article-title":"Redox imaging of human breast cancer core biopsies: a preliminary investigation","volume":"20","author":"Xu","year":"2013","journal-title":"Acad Radiol"},{"key":"10.1016\/j.acra.2025.11.014_bib18","first-page":"1068","article-title":"Mitochondrial complex I activity and NAD+\/NADH balance regulate breast cancer progression","volume":"123","author":"Santidrian","year":"2013","journal-title":"J\u00a0Clin\u00a0Investig"},{"key":"10.1016\/j.acra.2025.11.014_bib19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/cas.13886","article-title":"Increased nicotinamide adenine dinucleotide pool promotes colon cancer progression by suppressing reactive oxygen species level","volume":"110","author":"Hong","year":"2019","journal-title":"Cancer Sci"},{"key":"10.1016\/j.acra.2025.11.014_bib20","first-page":"247","article-title":"Potential biomarker for triple negative breast cancer invasiveness by optical redox imaging","volume":"1269","author":"Feng","year":"2021","journal-title":"Adv\u00a0Exp\u00a0Med\u00a0Biol"},{"key":"10.1016\/j.acra.2025.11.014_bib21","first-page":"410","article-title":"Optical redox imaging detects the effects of DEK oncogene knockdown on the redox state of MDA-MB-231 breast cancer cells","volume":"21","author":"Wen","year":"2019","journal-title":"Mol\u00a0Imaging Biol."},{"key":"10.1016\/j.acra.2025.11.014_bib22","series-title":"Natural\u00a0Biomarkers for\u00a0Cellular\u00a0Metabolism:\u00a0Biology\u00a0Techniques\u00a0Applications.","first-page":"273","article-title":"Autofluorescence perspective of cancer diagnostics.","author":"Li","year":"2014"},{"key":"10.1016\/j.acra.2025.11.014_bib23","first-page":"121","article-title":"Potential indexing of the invasiveness of breast cancer cells by mitochondrial redox ratios","volume":"923","author":"Sun","year":"2016","journal-title":"Adv\u00a0Exp\u00a0Med\u00a0Biol"},{"key":"10.1016\/j.acra.2025.11.014_bib24","first-page":"95","article-title":"Relationship between optical redox status and reactive oxygen species in cancer cells","volume":"9","author":"Podsednik","year":"2020","journal-title":"React Oxyg Species"},{"key":"10.1016\/j.acra.2025.11.014_bib25","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1158\/2159-8290.CD-12-0345","article-title":"Cancer cell metabolism: one hallmark, many faces","volume":"2","author":"Cantor","year":"2012","journal-title":"Cancer Discov"},{"key":"10.1016\/j.acra.2025.11.014_bib26","first-page":"883","article-title":"Intratumor heterogeneity and branched evolution revealed by multiregion sequencing","volume":"366","author":"Gerlinger","year":"2012","journal-title":"New Eng\u00a0J\u00a0Med"},{"key":"10.1016\/j.acra.2025.11.014_bib27","first-page":"53","article-title":"Mitochondria: are mitochondria accessory to metastasis?","volume":"51","author":"Amoedo","year":"2014","journal-title":"Int\u00a0J\u00a0Biochem\u00a0Cell Biol"},{"key":"10.1016\/j.acra.2025.11.014_bib28","first-page":"1454","article-title":"The role of mitochondrial electron transport in tumorigenesis and metastasis","volume":"1840","author":"Tan","year":"2014","journal-title":"Biochim\u00a0Biophys\u00a0Acta"},{"key":"10.1016\/j.acra.2025.11.014_bib29","first-page":"177","article-title":"Differential expression of PGC1alpha in intratumor redox subpopulations of breast cancer","volume":"1072","author":"Lin","year":"2018","journal-title":"Adv\u00a0Exp\u00a0Med\u00a0Biol"},{"key":"10.1016\/j.acra.2025.11.014_bib30","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0003-2697(85)90244-1","article-title":"High resolution readout of 3-D metabolic organ structure: an automated, low-temperature redox ratio-scanning instrument","volume":"148","author":"Quistorff","year":"1985","journal-title":"Anal Biochem"},{"key":"10.1016\/j.acra.2025.11.014_bib31","first-page":"172","article-title":"High-resolution three-dimensional scanning optical image system for intrinsic and extrinsic contrast agents in tissue","volume":"73","author":"Gu","year":"2002","journal-title":"Rev\u00a0Sci\u00a0Instrum"},{"key":"10.1016\/j.acra.2025.11.014_bib32","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.acra.2025.11.014_bib33","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1093\/bioinformatics\/btr427","article-title":"Comparative analysis of RNA-Seq alignment algorithms and the RNA-seq unified mapper (RUM)","volume":"27","author":"Grant","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.acra.2025.11.014_bib34","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: a bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.acra.2025.11.014_bib35","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.acra.2025.11.014_bib36","article-title":"Regulation of SIRT1 and its roles in inflammation","volume":"13","author":"Yang","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.acra.2025.11.014_bib37","first-page":"1307","article-title":"Foxo1 integrates insulin signaling with mitochondrial function in the liver","volume":"15","author":"Cheng","year":"2009","journal-title":"Nat\u00a0Med"},{"key":"10.1016\/j.acra.2025.11.014_bib38","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1038\/s41388-023-02592-y","article-title":"NAD(+) supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling","volume":"42","author":"Jiang","year":"2023","journal-title":"Oncogene"},{"key":"10.1016\/j.acra.2025.11.014_bib39","first-page":"2188","article-title":"PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells","volume":"106","author":"O'Hagan","year":"2009","journal-title":"Proc\u00a0Natl Acad\u00a0Sci\u00a0USA"},{"key":"10.1016\/j.acra.2025.11.014_bib40","first-page":"198","article-title":"The metabolic modulator PGC-1\u03b1 in cancer","volume":"9","author":"Bost","year":"2019","journal-title":"Am J Cancer Res"},{"key":"10.1016\/j.acra.2025.11.014_bib41","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.3390\/antiox12051075","article-title":"PGC-1\u03b1 is a master regulator of mitochondrial lifecycle and ROS stress response","volume":"12","author":"Abu Shelbayeh","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.acra.2025.11.014_bib42","first-page":"992","article-title":"PGC-1\u03b1 mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis","volume":"16","author":"LeBleu","year":"2014","journal-title":"Nat\u00a0Cell Biol"},{"key":"10.1016\/j.acra.2025.11.014_bib43","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.cmet.2017.09.006","article-title":"PGC-1\u03b1 promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs","volume":"26","author":"Andrzejewski","year":"2017","journal-title":"Cell Metab"},{"key":"10.1016\/j.acra.2025.11.014_bib44","first-page":"166","article-title":"Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?","volume":"64","author":"Cant\u00f3","year":"2012","journal-title":"Pharmacol\u00a0Rev"},{"key":"10.1016\/j.acra.2025.11.014_bib45","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1101\/gad.1164804","article-title":"Calorie restriction extends yeast life span by lowering the level of NADH","volume":"18","author":"Lin","year":"2004","journal-title":"Genes Dev"},{"key":"10.1016\/j.acra.2025.11.014_bib46","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.bbabio.2017.09.005","article-title":"Metabolic control by sirtuins and other enzymes that sense NAD(+), NADH, or their ratio","volume":"1858","author":"Anderson","year":"2017","journal-title":"Biochim Biophys Acta Bioenerg"},{"key":"10.1016\/j.acra.2025.11.014_bib47","doi-asserted-by":"crossref","first-page":"16456","DOI":"10.1074\/jbc.M501485200","article-title":"SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}","volume":"280","author":"Nemoto","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.acra.2025.11.014_bib48","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/nature03354","article-title":"Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1","volume":"434","author":"Rodgers","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.acra.2025.11.014_bib49","first-page":"21590","article-title":"Peroxisome proliferator-activated receptor gamma co-activator 1alpha; (PGC-1alpha;) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis","volume":"285","author":"Aquilano","year":"2010","journal-title":"J\u00a0Biol\u00a0Chem"},{"key":"10.1016\/j.acra.2025.11.014_bib50","doi-asserted-by":"crossref","first-page":"4732","DOI":"10.18632\/oncotarget.1963","article-title":"Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK\/Sirt1\/PGC-1alpha signaling","volume":"5","author":"Huang","year":"2014","journal-title":"Oncotarget"},{"key":"10.1016\/j.acra.2025.11.014_bib51","doi-asserted-by":"crossref","first-page":"2870","DOI":"10.1158\/1078-0432.CCR-14-2290","article-title":"SIRT1\/PGC1alpha-dependent increase in oxidative phosphorylation supports chemotherapy resistance of colon cancer","volume":"21","author":"Vellinga","year":"2015","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.acra.2025.11.014_bib52","doi-asserted-by":"crossref","first-page":"4004","DOI":"10.18632\/oncotarget.26958","article-title":"ETHE1 overexpression promotes SIRT1 and PGC1\u03b1 mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer","volume":"10","author":"Witherspoon","year":"2019","journal-title":"Oncotarget"},{"key":"10.1016\/j.acra.2025.11.014_bib53","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4161\/cam.4.2.10972","article-title":"Sirt1 and cell migration","volume":"4","author":"Tang","year":"2010","journal-title":"Cell Adh Migr"},{"key":"10.1016\/j.acra.2025.11.014_bib54","first-page":"10227","article-title":"SIRT1\/FOXO signaling pathway in breast cancer progression and metastasis","volume":"23","author":"Dilmac","year":"2022","journal-title":"Int\u00a0J\u00a0Mol\u00a0Sci"},{"key":"10.1016\/j.acra.2025.11.014_bib55","first-page":"3901","article-title":"MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice","volume":"120","author":"Wu","year":"2010","journal-title":"J\u00a0Clin\u00a0Investig"},{"key":"10.1016\/j.acra.2025.11.014_bib56","first-page":"884S","article-title":"Regulation of PGC-1\u03b1, a nodal regulator of mitochondrial biogenesis","volume":"93","author":"Fernandez-Marcos","year":"2011","journal-title":"Am\u00a0J\u00a0Clin\u00a0Nutr"},{"key":"10.1016\/j.acra.2025.11.014_bib57","doi-asserted-by":"crossref","first-page":"4764","DOI":"10.1016\/S0021-9258(17)30079-0","article-title":"Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals","volume":"254","author":"Chance","year":"1979","journal-title":"J Biol Chem"},{"key":"10.1016\/j.acra.2025.11.014_bib58","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.17.11.116015","article-title":"Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status","volume":"17","author":"Walsh","year":"2012","journal-title":"J Biomed Opt"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633225010657?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633225010657?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:06:34Z","timestamp":1778839594000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633225010657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":58,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S1076633225010657"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2025.11.014","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optical Redox Imaging of Breast Cancer NADH Redox Status Associated with PGC1\u03b1 Gene Expression","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2025.11.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Association of Academic Radiology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}