{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:48:11Z","timestamp":1792010891673,"version":"4.4.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017959","name":"Hebei Province Health Commission","doi-asserted-by":"publisher","award":["20241014"],"award-info":[{"award-number":["20241014"]}],"id":[{"id":"10.13039\/100017959","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["academicradiology.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Academic Radiology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.acra.2026.09.022","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:40:37Z","timestamp":1790714437000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Coronary Plaque Burden, Distribution, and Perivascular Fat Characteristics in Patients with Diabetes Mellitus: A Coronary CT Angiography Study"],"prefix":"10.1016","author":[{"given":"Xiaoyu","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxuan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongpeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9136-7136","authenticated-orcid":false,"given":"Xin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.acra.2026.09.022_bib1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/nrendo.2017.151","article-title":"Global aetiology and epidemiology of type 2 diabetes mellitus and its complications","volume":"14","author":"Zheng","year":"2018","journal-title":"Nat Rev Endocrinol"},{"issue":"2_suppl","key":"10.1016\/j.acra.2026.09.022_bib2","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1177\/2047487319878371","article-title":"Diabetes as a cardiovascular risk factor: an overview of global trends of macro and micro vascular complications","volume":"26","author":"Dal Canto","year":"2019","journal-title":"Eur J Prev Cardiol"},{"issue":"1","key":"10.1016\/j.acra.2026.09.022_bib3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/s41569-023-00900-3","article-title":"Roadmap on the use of artificial intelligence for imaging of vulnerable atherosclerotic plaque in coronary arteries","volume":"21","author":"F\u00f6llmer","year":"2024","journal-title":"Nat Rev Cardiol"},{"issue":"4","key":"10.1016\/j.acra.2026.09.022_bib4","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1093\/eurjpc\/zwab067","article-title":"Cardiovascular risk stratification by coronary computed tomography angiography imaging: current state\u2013of\u2013the\u2013art","volume":"29","author":"Antonopoulos","year":"2022","journal-title":"Eur J Prev Cardiol"},{"issue":"2","key":"10.1016\/j.acra.2026.09.022_bib5","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1056\/NEJMoa2415879","article-title":"Global effect of cardiovascular risk factors on lifetime estimates","volume":"393","author":"Global Cardiovascular Risk Consortium","year":"2025","journal-title":"N Engl J Med"},{"issue":"25","key":"10.1016\/j.acra.2026.09.022_bib6","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1016\/j.jacc.2025.09.1607","article-title":"Trends in prevalence, treatment, and control of cardiometabolic risk factors among adults with hypertension in the United States, 1999\u20132023","volume":"86","author":"Lee","year":"2025","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.acra.2026.09.022_bib7","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jacc.2025.04.070","article-title":"Plaque vulnerability and cardiovascular risk factor burden in acute coronary syndrome: an optical coherence tomography analysis","volume":"86","author":"Covani","year":"2025","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.acra.2026.09.022_bib8","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12933-021-01342-2","article-title":"Association between triglyceride\u2013glucose index and risk of arterial stiffness: a cohort study","volume":"20","author":"Wu","year":"2021","journal-title":"Cardiovasc Diabetol"},{"issue":"4","key":"10.1016\/j.acra.2026.09.022_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00395-024-01045-1","article-title":"Role of inflammatory signaling pathways involving the CD40\u2013CD40L\u2013TRAF cascade in diabetes and hypertension\u2013insights from animal and human studies","volume":"119","author":"Strohm","year":"2024","journal-title":"Basic Res Cardiol"},{"issue":"6","key":"10.1016\/j.acra.2026.09.022_bib10","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1093\/eurheartj\/ehz474","article-title":"Imaging residual inflammatory cardiovascular risk","volume":"41","author":"Antoniades","year":"2020","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.acra.2026.09.022_bib11","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.022879","article-title":"Pericoronary fat attenuation index is associated with vulnerable plaque components and local immune\u2013inflammatory activation in patients with non\u2013ST elevation acute coronary syndrome","volume":"11","author":"Sun","year":"2022","journal-title":"J Am Heart Assoc"},{"issue":"10444","key":"10.1016\/j.acra.2026.09.022_bib12","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1016\/S0140-6736(24)00596-8","article-title":"Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study","volume":"403","author":"Chan","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.acra.2026.09.022_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2025.112206","article-title":"Relationship between pericoronary fat attenuation index and quantitative plaque components in newly identified coronary plaques","volume":"190","author":"Zhang","year":"2025","journal-title":"Eur J Radiol"},{"issue":"8","key":"10.1016\/j.acra.2026.09.022_bib14","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1016\/j.jcmg.2021.02.026","article-title":"Prognostic value of RCA pericoronary adipose tissue CT\u2013attenuation beyond high\u2013risk plaques, plaque volume, and ischemia","volume":"14","author":"van Diemen","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"issue":"1","key":"10.1016\/j.acra.2026.09.022_bib15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/s12933-025-02694-9","article-title":"Pericoronary adipose tissue attenuation predicts compositional plaque changes: a 12-month longitudinal study in individuals with type 2 diabetes without symptoms or known coronary artery disease","volume":"24","author":"Overgaard","year":"2025","journal-title":"Cardiovasc Diabetol"},{"issue":"3","key":"10.1016\/j.acra.2026.09.022_bib16","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.122.014959","article-title":"Coronary inflammation and plaque vulnerability: a coronary computed tomography and optical coherence tomography study","volume":"16","author":"Yuki","year":"2023","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.acra.2026.09.022_bib17","article-title":"2023 Chinese guideline for lipid management","volume":"14","author":"Li","year":"2023","journal-title":"Front Pharmacol"},{"issue":"11","key":"10.1016\/j.acra.2026.09.022_bib18","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1016\/j.jcmg.2022.07.002","volume":"15","author":"Cury","year":"2022","journal-title":"JACC Cardiovasc Imaging"},{"issue":"1145","key":"10.1016\/j.acra.2026.09.022_bib19","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20220885","article-title":"Evaluation of pericoronary adipose tissue attenuation on CT","volume":"96","author":"Ma","year":"2023","journal-title":"Br J Radiol"},{"issue":"1","key":"10.1016\/j.acra.2026.09.022_bib20","article-title":"Associations among microvascular dysfunction, fatty acid metabolism, and diabetes","volume":"8","author":"Wu","year":"2023","journal-title":"Cardiovasc Innov Appl"},{"key":"10.1016\/j.acra.2026.09.022_bib21","article-title":"Endothelial dysfunction in vascular complications of diabetes: a comprehensive review of mechanisms and implications","volume":"15","author":"Yang","year":"2024","journal-title":"Front Endocrinol"},{"issue":"10","key":"10.1016\/j.acra.2026.09.022_bib22","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.3390\/antiox11101958","article-title":"Roles of oxidative stress and inflammation in vascular endothelial dysfunction\u2013related disease","volume":"11","author":"Higashi","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.acra.2026.09.022_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmpb.2023.107514","article-title":"Shear stress and plaque microenvironment induce heterogeneity: a multiscale microenvironment evolution model","volume":"235","author":"Pan","year":"2023","journal-title":"Comput Methods Prog Biomed"},{"issue":"5","key":"10.1016\/j.acra.2026.09.022_bib24","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.3390\/ijms26052196","article-title":"Diabetes\u2013driven atherosclerosis: updated mechanistic insights and novel therapeutic strategies","volume":"26","author":"Karakasis","year":"2025","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.acra.2026.09.022_bib25","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/s12933-025-02694-9","article-title":"Pericoronary adipose tissue attenuation predicts compositional plaque changes: a 12-month longitudinal study in individuals with type 2 diabetes without symptoms or known coronary artery disease","volume":"24","author":"Overgaard","year":"2025","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"10.1016\/j.acra.2026.09.022_bib26","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/s12933-024-02272-5","article-title":"The predictive value of lesion-specific pericoronary fat attenuation index for major adverse cardiovascular events in patients with type 2 diabetes","volume":"23","author":"Liu","year":"2024","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.acra.2026.09.022_bib27","first-page":"2606","article-title":"Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study","volume":"403","author":"Chan","year":"2024"},{"issue":"5","key":"10.1016\/j.acra.2026.09.022_bib28","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.3390\/ijms26052196","article-title":"Diabetes-driven atherosclerosis: updated mechanistic insights and novel therapeutic strategies","volume":"26","author":"Karakasis","year":"2025","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.acra.2026.09.022_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/dmrr.70167","article-title":"Intersecting molecular pathways in cardiovascular disease and diabetes mellitus: emerging roles of inflammation and therapeutics","author":"Anagnostopoulou","year":"2026","journal-title":"Diabetes Metab Res Rev"},{"issue":"8","key":"10.1016\/j.acra.2026.09.022_bib30","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/j.cmet.2021.07.001","article-title":"Cardiovascular disease in diabetes, beyond glucose","volume":"33","author":"Eckel","year":"2021","journal-title":"Cell Metab"},{"issue":"24","key":"10.1016\/j.acra.2026.09.022_bib31","doi-asserted-by":"crossref","first-page":"2830","DOI":"10.3390\/diagnostics14242830","article-title":"Diagnosis, pathophysiology and management of microvascular dysfunction in diabetes mellitus","volume":"14","author":"Jan","year":"2024","journal-title":"Diagnostics"},{"issue":"8033","key":"10.1016\/j.acra.2026.09.022_bib32","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/s41586-024-07993-x","article-title":"Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis","volume":"634","author":"Takaoka","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.acra.2026.09.022_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.atherosclerosis.2024.117545","article-title":"Modification of lipoprotein metabolism and function driving atherogenesis in diabetes","volume":"394","author":"Luciani","year":"2024","journal-title":"Atherosclerosis"},{"issue":"4","key":"10.1016\/j.acra.2026.09.022_bib34","doi-asserted-by":"crossref","DOI":"10.4239\/wjd.v16.i4.102751","article-title":"Effect of systolic blood pressure status on coronary inflammation and high-risk plaque characteristics","volume":"16","author":"Jiang","year":"2025","journal-title":"World J Diabetes"},{"key":"10.1016\/j.acra.2026.09.022_bib35","article-title":"Effect of metabolic syndrome on coronary artery atherosclerotic plaque in type 2 diabetes mellitus patients","volume":"16","author":"Zhang","year":"2025","journal-title":"Front Endocrinol"},{"issue":"12","key":"10.1016\/j.acra.2026.09.022_bib36","doi-asserted-by":"crossref","first-page":"6838","DOI":"10.1007\/s00330-020-07069-0","article-title":"Towards reference values of pericoronary adipose tissue attenuation: impact of coronary artery and tube voltage in coronary computed tomography angiography","volume":"30","author":"Ma","year":"2020","journal-title":"Eur Radiol"},{"issue":"5","key":"10.1016\/j.acra.2026.09.022_bib37","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1007\/s00330-024-11132-5","article-title":"The pericoronary adipose tissue attenuation in CT strongly depends on kernels and iterative reconstructions","volume":"35","author":"Lisi","year":"2025","journal-title":"Eur Radiol"}],"container-title":["Academic Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633226007579?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1076633226007579?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:16:50Z","timestamp":1792009010000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1076633226007579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":37,"alternative-id":["S1076633226007579"],"URL":"https:\/\/doi.org\/10.1016\/j.acra.2026.09.022","relation":{},"ISSN":["1076-6332"],"issn-type":[{"value":"1076-6332","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coronary Plaque Burden, Distribution, and Perivascular Fat Characteristics in Patients with Diabetes Mellitus: A Coronary CT Angiography Study","name":"articletitle","label":"Article Title"},{"value":"Academic Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.acra.2026.09.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Association of Academic Radiology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}