{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T13:12:54Z","timestamp":1793279574657,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Tropica"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.actatropica.2007.06.010","type":"journal-article","created":{"date-parts":[[2007,7,8]],"date-time":"2007-07-08T11:13:35Z","timestamp":1183893215000},"page":"231-241","source":"Crossref","is-referenced-by-count":49,"title":["Infection by Ascaris lumbricoides and bronchial hyper reactivity: An outstanding association in Venezuelan school children from endemic areas"],"prefix":"10.1016","volume":"103","author":[{"given":"I.","family":"Hagel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Cabrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Hurtado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Puccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.C.","family":"Di Prisco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Palenque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actatropica.2007.06.010_bib1","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1111\/j.1398-9995.1997.tb02530.x","article-title":"Expression of CD23 antigen and its ligands in children with extrinsic and intrinsic asthma","volume":"52","author":"Aberle","year":"1997","journal-title":"Allergy"},{"key":"10.1016\/j.actatropica.2007.06.010_bib2","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0035-9203(81)90146-2","article-title":"Skin sensitivity reactions in Nigerian children with bronchial asthma","volume":"75","author":"Aderele","year":"1981","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.actatropica.2007.06.010_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/eji.1830200120","article-title":"Inhibition of human interleukin -4 induced IgE synthesis by a subset of anti-CD23\/Fc epsilon RII monoclonal antibodies","volume":"20","author":"Bonnefoy","year":"1990","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib4","first-page":"64","article-title":"Valores de predicci\u00f3n en funci\u00f3n pulmonar","volume":"15","author":"Cobos","year":"1979","journal-title":"Arch. Bronconeumonol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib5","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/j.1365-2222.1992.tb02826.x","article-title":"Pictorial keys for the identification of domestic mites","volume":"22","author":"Colloff","year":"1992","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.actatropica.2007.06.010_bib6","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1046\/j.1365-2249.2002.01908.x","article-title":"Can intestinal helminth infections (geohelminths) affect the development and expression of asthma and allergic disease?","volume":"128","author":"Cooper","year":"2002","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib7","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1086\/315830","article-title":"Human infection with Ascaris lumbricoides is associated with a polarized cytokine response","volume":"182","author":"Cooper","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.actatropica.2007.06.010_bib8","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1136\/thx.54.7.606","article-title":"Prevalence of atopy, asthma symptoms and diagnosis, and the management of asthma: comparison of an affluent and non affluent country","volume":"54","author":"Faniran","year":"1999","journal-title":"Thorax"},{"key":"10.1016\/j.actatropica.2007.06.010_bib9","first-page":"273","article-title":"Issues in the assessment of nutritional status using anthropometry","volume":"72","author":"Gorstein","year":"1994","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.actatropica.2007.06.010_bib10","first-page":"241","article-title":"Role of the low affinity IgE receptor (CD23) on the IgE response against Ascaris lumbricoides in Warao Amerindian children from Venezuela","volume":"47","author":"Hagel","year":"2006","journal-title":"Invest. Clin."},{"key":"10.1016\/j.actatropica.2007.06.010_bib11","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1365-3024.1993.tb00615.x","article-title":"Modulation of the allergic reactivity of slum children by helminthic infection","volume":"15","author":"Hagel","year":"1993","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib12","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1159\/000236521","article-title":"Allergic reactivity of children of different socioeconomic levels in tropical populations","volume":"101","author":"Hagel","year":"1993","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/tropej\/49.3.136","article-title":"Defective regulation of the protective IgE response against the Intestinal helminth Ascaris lumbricoides in malnourished children","volume":"49","author":"Hagel","year":"2003","journal-title":"J. Trop. Pediatr."},{"key":"10.1016\/j.actatropica.2007.06.010_bib14","first-page":"37","article-title":"Factores inmunol\u00f3gicos protectores frente a la infecci\u00f3n por Ascaris lumbricoides en ni\u00f1os ind\u00edgenas y criollos de comunidades rurales de Venezuela","volume":"155","author":"Hagel","year":"2005","journal-title":"Bolet\u00edn de Malariolog\u00eda y Salud Ambiental"},{"key":"10.1016\/j.actatropica.2007.06.010_bib15","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0140-6736(00)02491-0","article-title":"Evolutionary adaptation of inflammatory immune responses in humans","volume":"356","author":"Le Souef","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.actatropica.2007.06.010_bib16","first-page":"547","article-title":"Diagnosis of atopic conditions in the tropics","volume":"51","author":"Lynch","year":"1983","journal-title":"Ann. Allergy"},{"key":"10.1016\/j.actatropica.2007.06.010_bib17","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1136\/thx.54.8.659","article-title":"Parasite Infections and the risk of asthma and atopy","volume":"54","author":"Lynch","year":"1999","journal-title":"Thorax"},{"key":"10.1016\/j.actatropica.2007.06.010_bib18","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0091-6749(98)70386-0","article-title":"Relationship between helminthic infection and IgE response in atopic and non-atopic children in a tropical environment","volume":"101","author":"Lynch","year":"1998","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1159\/000236167","article-title":"Bronchoconstriction in helminthic infection","volume":"98","author":"Lynch","year":"1992","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib20","first-page":"97","article-title":"Bronchial challenge of tropical asthmatics with Ascaris lumbricoides","volume":"2","author":"Lynch","year":"1992","journal-title":"J. Invest. Allergol. Clin. Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib21","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1164\/ajrccm.156.1.9606081","article-title":"Clinical improvement of asthma after anthelminthic treatment in a tropical situation","volume":"156","author":"Lynch","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.actatropica.2007.06.010_bib22","doi-asserted-by":"crossref","first-page":"255","DOI":"10.2223\/JPED.1503","article-title":"Total IgE levels in respiratory allergy: study of patients at high risk of helminthic infection","volume":"82","author":"Medeiros","year":"2006","journal-title":"J. Pediatr. (Rio J.)"},{"key":"10.1016\/j.actatropica.2007.06.010_bib23","unstructured":"Melvin, D., Brooke, M., 1989. M\u00e9todos de laboratorio para diagn\u00f3stico de parasitosis Intestinales. Editorial Mexicana, M\u00e9xico, pp. 203\u2013208."},{"key":"10.1016\/j.actatropica.2007.06.010_bib24","unstructured":"Montresor, A., Crompton, D.W.T., Bundy, D.A.P., Hall, A., Savioli, L., 1998. Guidelines for the evaluation of soil transmitted helminthiasis and schistosomiasis at community level. WHO\/CTD\/SIP\/98.1. Geneva: World Health Organization."},{"key":"10.1016\/j.actatropica.2007.06.010_bib25","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1128\/IAI.71.5.2607-2614.2003","article-title":"Changes in pulmonary function and parasite burden in rats infected with Strongyloides venezuelensis concomitant with induction of allergic airway inflammation","volume":"71","author":"Negrao-Correa","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.actatropica.2007.06.010_bib26","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/j.1365-2222.2006.02479.x","article-title":"Respiratory atopic disease, Ascaris-immunoglobulin E and tuberculin testing in urban South African Children","volume":"36","author":"Obihara","year":"2006","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.actatropica.2007.06.010_bib27","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1164\/ajrccm.164.4.2102018","article-title":"Activated cytotoxic CD8+ T lymphocytes contribute to the pathology of asthma death","volume":"64","author":"O'Sullivan","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.actatropica.2007.06.010_bib28","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1164\/rccm.2107020","article-title":"Ascaris lumbricoides infection is associated with increased risk of childhood asthma and atopy in rural China","volume":"165","author":"Palmer","year":"2002","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.actatropica.2007.06.010_bib29","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.prrv.2004.04.002","article-title":"Mechanisms of Rhinovirus induced asthma","volume":"5","author":"Papadopoulos","year":"2004","journal-title":"Paediatr. Respir. Rev."},{"key":"10.1016\/j.actatropica.2007.06.010_bib30","first-page":"77","article-title":"The influence of environment and parasitism on the prevalence of asthma in the Venezuelan regions","volume":"32","author":"Perdomo de Ponce","year":"1991","journal-title":"Invest. Clin."},{"key":"10.1016\/j.actatropica.2007.06.010_bib31","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/0091-6749(89)90128-0","article-title":"Dust Mites allergens and asthma. A World Wide problem","volume":"83","author":"Platts Mills","year":"1989","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib32","unstructured":"Rep\u00fablica Bolivariana de Venezuela Gabinete Social, 2004. Cumpliendo con las metas del Milenio. 2004. CDB Publishers, Caracas, Venezuela. pp. 75\u201386."},{"key":"10.1016\/j.actatropica.2007.06.010_bib33","unstructured":"Rep\u00fablica Bolivariana de Venezuela, Ministerio de Salud, 2005. Bolet\u00edn Epidemiol\u00f3gico. 52: 19\u201320."},{"key":"10.1016\/j.actatropica.2007.06.010_bib34","doi-asserted-by":"crossref","unstructured":"The International Study of Asthma and Allergies in Childhood. Steering Committee, 1998. Lancet 351, 1220\u20131221.","DOI":"10.1016\/S0140-6736(98)22017-4"},{"key":"10.1016\/j.actatropica.2007.06.010_bib35","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/S0140-6736(00)03206-2","article-title":"Decrease atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10","volume":"356","author":"van den Biggelaar","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.actatropica.2007.06.010_bib36","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1365-2222.2004.01899.x","article-title":"A double-blind placebo controlled birch allergy vaccination study: inhibition of CD23-mediated serum-immunoglobulin E-facilitated allergen presentation","volume":"34","author":"van Neerven","year":"2004","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.actatropica.2007.06.010_bib37","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0091-6749(00)90067-8","article-title":"Parasites and asthma\/allergy: what is the relationship?","volume":"105","author":"Weiss","year":"2000","journal-title":"J. Allergy Clin. immunol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib38","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S1567-5769(01)00187-4","article-title":"AntiCD23 monoclonal antibody inhibits germline Cepsilon transcription in B cells","volume":"2","author":"Yabuuchi","year":"2002","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.actatropica.2007.06.010_bib39","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S1471-4906(01)01958-5","article-title":"Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease","volume":"22","author":"Yazdanbakhsh","year":"2001","journal-title":"Trends Immunol."}],"container-title":["Acta Tropica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X07001684?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X07001684?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,6]],"date-time":"2019-01-06T06:52:15Z","timestamp":1546757535000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001706X07001684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S0001706X07001684"],"URL":"https:\/\/doi.org\/10.1016\/j.actatropica.2007.06.010","relation":{},"ISSN":["0001-706X"],"issn-type":[{"value":"0001-706X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}