{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T19:06:10Z","timestamp":1793387170295,"version":"4.5.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002261","name":"Russian Foundation for Basic Research","doi-asserted-by":"publisher","award":["NK 13-04-98056\\13"],"award-info":[{"award-number":["NK 13-04-98056\\13"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Tropica"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.actatropica.2014.07.004","type":"journal-article","created":{"date-parts":[[2014,7,10]],"date-time":"2014-07-10T20:43:10Z","timestamp":1405024990000},"page":"53-56","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Opisthorchis felineus liver fluke invasion is an environmental factor modifying genetic risk of atopic bronchial asthma"],"prefix":"10.1016","volume":"139","author":[{"given":"Irina V.","family":"Saltykova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludmila M.","family":"Ogorodova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Yu.","family":"Bragina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery P.","family":"Puzyrev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1439-6259","authenticated-orcid":false,"given":"Maxim B.","family":"Freidin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actatropica.2014.07.004_bib0005","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1183\/09031936.00138707","article-title":"Global strategy for asthma management and prevention: GINA executive summary","volume":"31","author":"Bateman","year":"2008","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0010","first-page":"221","article-title":"Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population","volume":"4","author":"Begh\u00e9","year":"2007","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.actatropica.2014.07.004_bib0015","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1056\/NEJMoa1211592","article-title":"Rhinovirus wheezing illness and genetic risk of childhood-onset asthma","volume":"368","author":"Cal\u0131\u015fkan","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0020","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/j.1365-2222.2007.02913.x","article-title":"Association between suppressors of cytokine signalling, T-helper type 1\/T-helper type 2 balance and allergic sensitization in children","volume":"8","author":"Daegelmann","year":"2008","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.actatropica.2014.07.004_bib0025","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1016\/j.jaci.2012.07.051","article-title":"Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes","volume":"130","author":"Daley","year":"2012","journal-title":"Allergy Clin. Immunol."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0030","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1159\/000095295","article-title":"Allelic polymorphisms in the interleukin-4 promoter regions and their association with bronchial asthma among the Russian population","volume":"141","author":"Gervaziev","year":"2006","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0035","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S1074-7613(00)80254-X","article-title":"Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice","volume":"4","author":"Haziot","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/j.actatropica.2014.07.004_bib0040","doi-asserted-by":"crossref","first-page":"6274","DOI":"10.4049\/jimmunol.174.10.6274","article-title":"Analysis of the 5q31-q33 locus shows an association between IL13-1055C\/T IL-13-591A\/G polymorphisms and Schistosoma haematobium infections","volume":"174","author":"Kouriba","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0045","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1164\/rccm.200603-331OC","article-title":"Asthma and current intestinal parasite infection: systematic review and meta-analysis","volume":"174","author":"Leonardi-Bee","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0050","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1513\/pats.200702-035AW","article-title":"CD14, endotoxin, and asthma risk: actions and interactions","volume":"4","author":"Martinez","year":"2007","journal-title":"Proc. Am. Thorac. Soc."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0055","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.parint.2011.07.021","article-title":"Opisthorchis felineus and Metorchis bilis are the main agents of liver fluke infection of humans in Russia","volume":"61","author":"Mordvinov","year":"2012","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0060","first-page":"37","article-title":"Genetic diagnostic technique for opisthorchiasis","volume":"7","author":"Ogorodova","year":"2009","journal-title":"Klin. Lab. Diagn."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0065","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s00436-007-0588-6","article-title":"A pilot screening of prevalence of atopic states and opisthorchosis and their relationship in people of Tomsk Oblast","volume":"101","author":"Ogorodova","year":"2007","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0070","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/sj.gene.6364030","article-title":"An asthma-associated genetic variant of STAT6 predicts low burden of ascaris worm infestation","volume":"5","author":"Peisong","year":"2004","journal-title":"Genes Immun."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0075","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1126\/science.282.5396.2085","article-title":"Defective LPS signaling in C3H\/HeJ and C57BL\/10ScCr mice: mutations in Tlr4 gene","volume":"282","author":"Poltorak","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.actatropica.2014.07.004_bib0080","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jaci.2004.10.006","article-title":"Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes","volume":"115","author":"Pyk\u00e4l\u00e4inen","year":"2005","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0085","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/S0020-7519(03)00175-9","article-title":"Genetics of susceptibility to human helminth infection","volume":"33","author":"Quinnell","year":"2003","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0090","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1111\/j.1365-2222.2008.03027.x","article-title":"Early infection with Trichuris trichiura and allergen skin test reactivity in later childhood","volume":"38","author":"Rodrigues","year":"2008","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.actatropica.2014.07.004_bib0095","doi-asserted-by":"crossref","first-page":"13003","DOI":"10.1073\/pnas.202477099","article-title":"Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation","volume":"99","author":"Seki","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.actatropica.2014.07.004_bib0100","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1164\/rccm.200810-1533OC","article-title":"CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adults","volume":"179","author":"Smit","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"Suppl. 1","key":"10.1016\/j.actatropica.2014.07.004_bib0105","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1136\/thorax.55.suppl_1.S2","article-title":"Family size, infection and atopy: the first decade of the hygiene hypothesis","volume":"55","author":"Strachan","year":"2000","journal-title":"Thorax"},{"key":"10.1016\/j.actatropica.2014.07.004_bib0110","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/ACI.0b013e32833653d7","article-title":"Gene\u2013environment interactions in asthma and allergy: the end of the beginning?","volume":"10","author":"Vercelli","year":"2010","journal-title":"Curr. Opin. Allergy Clin. Immunol."}],"container-title":["Acta Tropica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X14002265?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X14002265?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T17:37:22Z","timestamp":1717004242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001706X14002265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":22,"alternative-id":["S0001706X14002265"],"URL":"https:\/\/doi.org\/10.1016\/j.actatropica.2014.07.004","relation":{},"ISSN":["0001-706X"],"issn-type":[{"value":"0001-706X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Opisthorchis felineus liver fluke invasion is an environmental factor modifying genetic risk of atopic bronchial asthma","name":"articletitle","label":"Article Title"},{"value":"Acta Tropica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actatropica.2014.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}