{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:34:44Z","timestamp":1783557284223,"version":"3.55.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"LOCTI-Universidad de Carabobo","award":["1.21"],"award-info":[{"award-number":["1.21"]}]},{"name":"VU Fondsendesk"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Tropica"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1016\/j.actatropica.2014.08.003","type":"journal-article","created":{"date-parts":[[2014,8,13]],"date-time":"2014-08-13T03:54:01Z","timestamp":1407902041000},"page":"68-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Long-term effect of mass chemotherapy, transmission and risk factors for Schistosoma mansoni infection in very low endemic communities of Venezuela"],"prefix":"10.1016","volume":"140","author":[{"given":"Stefanie N.","family":"Hofstede","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Tami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevieve A.F.S.","family":"van Liere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Ball\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renzo N.","family":"Incani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actatropica.2014.08.003_bib0005","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1590\/S0074-02761999000200002","article-title":"The last fifteen years of schistosomiasis in Venezuela: features and evolution","volume":"94","author":"Alarc\u00f3n de Noya","year":"1999","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"Suppl. 1","key":"10.1016\/j.actatropica.2014.08.003_bib0010","first-page":"201","article-title":"Esquistosomiasis en el caser\u00edo de Los Naranjos, Estado Carabobo","volume":"43","author":"Alarc\u00f3n de Noya","year":"1992","journal-title":"Acta Cient. Venez."},{"issue":"Suppl 1","key":"10.1016\/j.actatropica.2014.08.003_bib0015","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1590\/S0074-02762006000900006","article-title":"Low transmission areas of schistosomiasis in Venezuela: consequences on the diagnosis, treatment, and control","volume":"101","author":"Alarc\u00f3n de Noya","year":"2006","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.actatropica.2014.08.003_bib0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.actatropica.2007.04.018","article-title":"Detection of schistosomiasis cases in low-transmission areas based on coprologic and serologic criteria: the Venezuelan experience","volume":"103","author":"Alarc\u00f3n de Noya","year":"2007","journal-title":"Acta Trop."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0025","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0030","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1128\/CDLI.12.2.280-286.2005","article-title":"Detection of Schistosoma mansoni membrane antigens by immunoblot analysis of sera of patients from low-transmission areas","volume":"12","author":"Cesari","year":"2005","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0035","first-page":"29","article-title":"Evaluaci\u00f3n del IEFA como t\u00e9cnica de inmunodiagn\u00f3stico en el programa de lucha contra la bilharziosis","volume":"42","author":"Cesari","year":"2002","journal-title":"Bol. Mal. San. Amb."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0040","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0001-706X(00)00122-4","article-title":"The global status of schistosomiasis and its control","volume":"77","author":"Chitsulo","year":"2000","journal-title":"Acta Trop."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0045","first-page":"CD000528","article-title":"Drugs for treating Schistosoma mansoni infection","volume":"2","author":"Danso-Appiah","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"issue":"Suppl. 1","key":"10.1016\/j.actatropica.2014.08.003_bib0050","first-page":"261","article-title":"Schistosomiasis in the Manuare village, Carabobo state, Venezuela","volume":"4","author":"Delgado","year":"1993","journal-title":"Acta Cient. Venez."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0055","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0001-706X(02)00045-1","article-title":"The global epidemiological situation of schistosomiasis and new approaches to control and research","volume":"82","author":"Engels","year":"2002","journal-title":"Acta Trop."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0060","doi-asserted-by":"crossref","first-page":"e897","DOI":"10.1371\/journal.pntd.0000897","article-title":"Observed reductions in Schistosoma mansoni transmission from large-scale administration of praziquantel in Uganda: a mathematical modelling study","volume":"4","author":"French","year":"2010","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0065","first-page":"172","article-title":"Frecuencia y morbilidad de la esquistosomiasis mansoni en una poblaci\u00f3n tradicionalmente end\u00e9mica, Seitifero-Valle de Manuare, al sur del Estado Carabobo","volume":"48","author":"Garc\u00eda","year":"1997","journal-title":"Acta Cient. Venez."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0070","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s00436-005-0047-1","article-title":"The efficacy of human schistosomicide treatment may depend on the rate of transmission","volume":"98","author":"Garcia","year":"2006","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0075","doi-asserted-by":"crossref","first-page":"509","DOI":"10.4269\/ajtmh.1991.45.509","article-title":"Repeated community-based chemotherapy for the control of Schistosoma mansoni: effect of screening and selective treatment on prevalences and intensities of infection","volume":"45","author":"Gryseels","year":"1991","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"Suppl. 4","key":"10.1016\/j.actatropica.2014.08.003_bib0080","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1590\/S0074-02761987000800014","article-title":"The Venezuelan experience in the control of schistosomiasis mansoni","volume":"82","author":"Incani","year":"1987","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"Suppl.","key":"10.1016\/j.actatropica.2014.08.003_bib0085","first-page":"119","article-title":"La bilharziosis en Venezuela desde el punto de vista sanitario. II. Epidemiolog\u00eda y m\u00e9todos de lucha","volume":"10","author":"Jove","year":"1955","journal-title":"G.E.N."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0090","first-page":"397","article-title":"A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni","volume":"14","author":"Katz","year":"1972","journal-title":"Rev. Inst. Med. Trop. S\u00e3o Paulo"},{"key":"10.1016\/j.actatropica.2014.08.003_bib0095","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.actatropica.2014.08.003_bib0100","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/S0140-6736(12)61689-4","article-title":"Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Murray","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.actatropica.2014.08.003_bib0105","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1093\/infdis\/95.1.86","article-title":"Anti-egg precipitins in the serum of humans infected with Schistosoma mansoni","volume":"95","author":"Oliver-Gonz\u00e1lez","year":"1954","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0110","series-title":"Biomphalaria Snails and Larval Trematodes","first-page":"215","article-title":"The biological control of the snail hosts of schistosomes: the role of competitor snails and biological invasions","author":"Pointier","year":"2011"},{"key":"10.1016\/j.actatropica.2014.08.003_bib0115","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.3109\/08820138909030608","article-title":"Immunodiagnosis of Schistosomiasis mansoni with APIA (alkaline phosphatase immunoassay)","volume":"18","author":"Pujol","year":"1989","journal-title":"Immunol. Invest."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0120","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1365-3024.1990.tb00947.x","article-title":"Antigenicity of adult Schistosoma mansoni alkaline phosphatase","volume":"12","author":"Pujol","year":"1990","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0125","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0001-706X(02)00006-2","article-title":"Morbidity control of schistosomiasis in China","volume":"82","author":"Qing-Wu","year":"2002","journal-title":"Acta Trop."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0130","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.actatropica.2012.04.013","article-title":"Time to set the agenda for schistosomiasis elimination","volume":"128","author":"Rollinson","year":"2013","journal-title":"Acta Trop."},{"issue":"Suppl. 1","key":"10.1016\/j.actatropica.2014.08.003_bib0135","first-page":"171","article-title":"Esquistosomiasis en el Valle de Los Naranjos, Estado Carabobo, un foco de alta transmisi\u00f3n I. Epidemiolog\u00eda b\u00e1sica","volume":"4","author":"Salas","year":"1997","journal-title":"Acta Cient. Venez."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0140","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S1473-3099(06)70521-7","article-title":"Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk","volume":"6","author":"Steinmann","year":"2006","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0145","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications","volume":"76","author":"Towbin","year":"1979","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0150","doi-asserted-by":"crossref","first-page":"760","DOI":"10.4269\/ajtmh.1999.61.760","article-title":"The contribution of host-related factors to low cure rates of praziquantel for the treatment of Schistosoma mansoni in Senegal","volume":"61","author":"van Lieshout","year":"1999","journal-title":"Am J. Trop. Med. Hyg."},{"key":"10.1016\/j.actatropica.2014.08.003_bib0155","series-title":"WHO Tech. Rep. Ser. 912","first-page":"1","article-title":"Prevention and control of schistosomiasis and soil-transmitted helminthiasis: report of a WHO Expert Committee","author":"WHO","year":"2002"},{"key":"10.1016\/j.actatropica.2014.08.003_bib0160","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/S0169-4758(98)01318-0","article-title":"Patterns in parasite epidemiology: the peak shift","volume":"14","author":"Woolhouse","year":"1998","journal-title":"Parasitol. Today"}],"container-title":["Acta Tropica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X14002563?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X14002563?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T01:10:26Z","timestamp":1598145026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001706X14002563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":32,"alternative-id":["S0001706X14002563"],"URL":"https:\/\/doi.org\/10.1016\/j.actatropica.2014.08.003","relation":{},"ISSN":["0001-706X"],"issn-type":[{"value":"0001-706X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term effect of mass chemotherapy, transmission and risk factors for Schistosoma mansoni infection in very low endemic communities of Venezuela","name":"articletitle","label":"Article Title"},{"value":"Acta Tropica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actatropica.2014.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}