{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:39:58Z","timestamp":1778575198099,"version":"3.51.4"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Tropica"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.actatropica.2018.03.002","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T02:44:06Z","timestamp":1520477046000},"page":"264-270","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"special_numbering":"C","title":["Evaluating a point-of-care circulating cathodic antigen test (POC-CCA) to detect Schistosoma mansoni infections in a low endemic area in north-eastern Brazil"],"prefix":"10.1016","volume":"182","author":[{"given":"Fernando Schemelzer Moraes","family":"Bezerra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8069-5495","authenticated-orcid":false,"given":"Joames Kauffimann Freitas","family":"Leal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Silva","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta Cristhiany Cunha","family":"Pinheiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7982-1757","authenticated-orcid":false,"suffix":"Jr.","given":"Alberto Novaes","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Silva-Moraes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naftale","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.actatropica.2018.03.002_bib0005","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.actatropica.2014.04.001","article-title":"Evaluation of circulating cathodic antigen (CCA) urine-cassette assay as a survey tool for Schistosoma mansoni in different transmission settings within Bugiri District, Uganda","volume":"136","author":"Adriko","year":"2014","journal-title":"Acta Trop."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.002_bib0010","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.actatropica.2007.04.018","article-title":"Detection of schistosomiasis cases in low-transmission areas based on coprologic and serologic criteria The Venezuelan experience","volume":"103","author":"Alarc\u00f3n de Noya","year":"2007","journal-title":"Acta Trop."},{"issue":"4","key":"10.1016\/j.actatropica.2018.03.002_bib0015","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1590\/S0037-86822012000400019","article-title":"Increased detection of schistosomiasis with Kato-Katz and SWAP-IgG-ELISA in a Northeastern Brazil low-intensity transmission area","volume":"45","author":"Carneiro","year":"2012","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"8","key":"10.1016\/j.actatropica.2018.03.002_bib0020","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1590\/0074-0276130202","article-title":"A conventional polymerase chain reaction-based method for the diagnosis of human schistosomiasis in stool samples from individuals in a low-endemicity area","volume":"108","author":"Carneiro","year":"2013","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"2","key":"10.1016\/j.actatropica.2018.03.002_bib0025","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.pt.2012.11.003","article-title":"Schistosomiasis in areas of low endemicity: a new era in diagnosis","volume":"29","author":"Cavalcanti","year":"2013","journal-title":"Trends Parasitol."},{"issue":"6","key":"10.1016\/j.actatropica.2018.03.002_bib0030","doi-asserted-by":"crossref","first-page":"e0004778","DOI":"10.1371\/journal.pntd.0004778","article-title":"Improvement of POC-CCA interpretation by using lyophilization of urine from patients with schistosoma mansoni low worm burden: towards an elimination of doubts about the concept of trace","volume":"10","author":"Coelho","year":"2016","journal-title":"PLoS Negl. Trop Dis."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.002_bib0035","doi-asserted-by":"crossref","first-page":"426","DOI":"10.4269\/ajtmh.12-0639","article-title":"A five-country evaluation of a point-of-care circulating cathodic antigen urine assay for the prevalence of Schistosoma mansoni","volume":"88","author":"Colley","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.actatropica.2018.03.002_bib0040","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s40249-017-0275-5","article-title":"Schistosomiasis is more prevalent than previously thought: what does it mean for public health goals, policies, strategies, guidelines and intervention programs?","volume":"6","author":"Colley","year":"2017","journal-title":"Infect. Dis. Poverty"},{"issue":"14","key":"10.1016\/j.actatropica.2018.03.002_bib0045","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1017\/S0031182014000626","article-title":"Tools for diagnosis, monitoring and screening of Schistosoma infections utilizing lateral-flow based assays and upconverting phosphor labels","volume":"141","author":"Corstjens","year":"2014","journal-title":"Parasitology"},{"issue":"11","key":"10.1016\/j.actatropica.2018.03.002_bib0050","doi-asserted-by":"crossref","first-page":"e1384","DOI":"10.1371\/journal.pntd.0001384","article-title":"Accuracy of urine circulating cathodic antigen (CCA) test for Schistosoma mansoni diagnosis in different settings of C\u00f4te d'Ivoire","volume":"5","author":"Coulibaly","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"12","key":"10.1016\/j.actatropica.2018.03.002_bib0055","doi-asserted-by":"crossref","first-page":"e1917","DOI":"10.1371\/journal.pntd.0001917","article-title":"Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium","volume":"6","author":"Coulibaly","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.002_bib0060","doi-asserted-by":"crossref","first-page":"e2109","DOI":"10.1371\/journal.pntd.0002109","article-title":"Accuracy of urine circulating cathodic antigen test for the diagnosis of Schistosoma mansoni in preschool-aged children before and after treatment","volume":"7","author":"Coulibaly","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.actatropica.2018.03.002_bib0065","first-page":"CD000528","article-title":"Drugs for treating Schistosoma mansoni infection","author":"Danso-Appiah","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"issue":"2\u20133","key":"10.1016\/j.actatropica.2018.03.002_bib0070","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.actatropica.2008.09.016","article-title":"The effect of the number of stool samples on the observed prevalence and the infection intensity with Schistosoma mansoni among a population in an area of low transmission","volume":"108","author":"Enk","year":"2008","journal-title":"Acta Trop."},{"issue":"12","key":"10.1016\/j.actatropica.2018.03.002_bib0075","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1007\/s10096-014-2196-6","article-title":"Evaluation of the sensitivity of IgG and IgM ELISA in detecting Schistosoma mansoni infections in a low endemicity setting","volume":"33","author":"Espirito-Santo","year":"2014","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.actatropica.2018.03.002_bib0080","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.exppara.2017.04.001","article-title":"Optimization of the Helmintex method for schistosomiasis diagnosis","volume":"177","author":"Favero","year":"2017","journal-title":"Exp. Parasitol."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.002_bib0085","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1590\/0037-8682-0231-2013","article-title":"Diagnosing schistosomiasis: where are we?","volume":"47","author":"Gomes","year":"2014","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.002_bib0090","doi-asserted-by":"crossref","DOI":"10.1590\/S0074-02762013000300011","article-title":"Schistosoma mansoni in a low-prevalence area in Brazil: the importance of additional methods for the diagnosis of hard-to-detect individual carriers by low-cost immunological assays","volume":"108","author":"Grenfell","year":"2013","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"6","key":"10.1016\/j.actatropica.2018.03.002_bib0095","first-page":"397","article-title":"A simple device for quantitative stool thick-smear technique in Schistosomiasis mansoni","volume":"14","author":"Katz","year":"1972","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"issue":"5","key":"10.1016\/j.actatropica.2018.03.002_bib0100","first-page":"781","article-title":"Preliminary trials with praziquantel in human infections due to Schistosoma mansoni","volume":"57","author":"Katz","year":"1979","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.actatropica.2018.03.002_bib0105","unstructured":"Katz, N., et al., 2017. Current situation of Shistosomiasis mansoni and soil-transmitted helminth. XXIV FLAP 2017, Santiago de Chile, Accepted November 2017."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.002_bib0110","doi-asserted-by":"crossref","first-page":"605","DOI":"10.4269\/ajtmh.15-0725","article-title":"Comparison of schistosoma mansoni prevalence and intensity of infection, as determined by the circulating cathodic antigen urine assay or by the kato-Katz fecal assay: a systematic review","volume":"94","author":"Kittur","year":"2016","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"9","key":"10.1016\/j.actatropica.2018.03.002_bib0115","doi-asserted-by":"crossref","first-page":"e3139","DOI":"10.1371\/journal.pntd.0003139","article-title":"Sensitivity and specificity of multiple Kato-Katz thick smears and a circulating cathodic antigen test for Schistosoma mansoni diagnosis pre- and post-repeated-praziquantel treatment","volume":"8","author":"Lamberton","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.002_bib0120","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.002_bib0125","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.trstmh.2006.11.009","article-title":"Field-based evaluation of a reagent strip test for diagnosis of Schistosoma mansoni by detecting circulating cathodic antigen in urine before and after chemotherapy","volume":"101","author":"Legesse","year":"2007","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.002_bib0130","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4269\/ajtmh.13-0104","article-title":"Diagnosis of Schistosoma mansoni without the stool: comparison of three diagnostic tests to detect Schistosoma mansoni infection from filtered urine in Zambia","volume":"89","author":"Lodh","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"14","key":"10.1016\/j.actatropica.2018.03.002_bib0135","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.ijpara.2014.07.009","article-title":"2014, trends in Schistosomiasis-related mortality in Brazil, 2000\u20132011","volume":"44","author":"Martins-Melo","year":"2014","journal-title":"Int. J. Parasitol."},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.002_bib0140","doi-asserted-by":"crossref","first-page":"e0003959","DOI":"10.1371\/journal.pntd.0003959","article-title":"Is PCR the next reference standard for the diagnosis of schistosoma in stool? A comparison with microscopy in Senegal and Kenya","volume":"9","author":"Meurs","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.actatropica.2018.03.002_bib0145","series-title":"Vigil\u00e2ncia Da Esquistossomose Mansoni: Diretrizes t\u00e9cnicas","author":"Minist\u00e9rio da Sa\u00fade","year":"2014"},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.002_bib0150","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1590\/S0074-02762012000700006","article-title":"The combination of three faecal parasitological methods to improve the diagnosis of schistosomiasis mansoni in a low endemic setting in the state of Cear\u00e1, Brazil","volume":"107","author":"Pinheiro","year":"2012","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"2","key":"10.1016\/j.actatropica.2018.03.002_bib0155","doi-asserted-by":"crossref","first-page":"157","DOI":"10.4269\/ajtmh.2002.66.157","article-title":"Detection by polymerase chain reaction of Schistosoma mansoni DNA in human s\u00e9rum and feces","volume":"66","author":"Pontes","year":"2002","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"2","key":"10.1016\/j.actatropica.2018.03.002_bib0160","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.actatropica.2012.04.013","article-title":"Time to set the agenda for schistosomiasis elimination","volume":"128","author":"Rollinson","year":"2013","journal-title":"Acta Trop."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.002_bib0165","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/0014-4894(86)90184-0","article-title":"Schistosoma mansoni: chemotherapy of infections of different ages","volume":"61","author":"Sabah","year":"1986","journal-title":"Exp. Parasitol."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.002_bib0170","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.actatropica.2008.11.015","article-title":"Sequential analysis of helminth egg output in human stool samples following albendazole and praziquantel administration","volume":"109","author":"Scherrer","year":"2009","journal-title":"Acta Trop."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.002_bib0175","doi-asserted-by":"crossref","first-page":"e951","DOI":"10.1371\/journal.pntd.0000951","article-title":"Evaluation of urine CCA assays for detection of Schistosoma mansoni infection in Western Kenya","volume":"5","author":"Shane","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.002_bib0180","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1590\/S0074-02762011000700010","article-title":"Evaluation of two coproscopic techniques for the diagnosis of schistosomiasis in a low-transmission area in the state of Minas Gerais, Brazil","volume":"106","author":"Siqueira","year":"2011","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.002_bib0185","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1590\/0037-8682-0070-2016","article-title":"Performance of POC-CCA\u00ae in diagnosis of schistosomiasis mansoni in individuals with low parasite burden","volume":"49","author":"Siqueira","year":"2016","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.002_bib0190","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1586\/14787210.2013.811931","article-title":"Advocacy, policies and practicalities of preventive chemotherapy campaigns for African children with schistosomiasis","volume":"11","author":"Stothard","year":"2013","journal-title":"Expert Rev. Anti Infect. Ther."},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.002_bib0195","doi-asserted-by":"crossref","first-page":"e1758","DOI":"10.1371\/journal.pntd.0001758","article-title":"Evaluation of circulating cathodic antigen (CCA) urine-tests for diagnosis of Schistosoma mansoni infection in Cameroon","volume":"6","author":"Tchuem Tchuent\u00e9","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"4","key":"10.1016\/j.actatropica.2018.03.002_bib0200","doi-asserted-by":"crossref","first-page":"e2807","DOI":"10.1371\/journal.pntd.0002807","article-title":"Diagnostic performance of Schistosoma real-time PCR in urine samples from Kenyan children infected with Schistosoma haematobium: day-to-day variation and follow-up after praziquantel treatment","volume":"8","author":"Vinkeles Melchers","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.actatropica.2018.03.002_bib0205","series-title":"Preventive Chemotherapy in Human Helminthiasis. Coordinated Use of Anthelminthic Drugs in Control Interventions: a Manual for Health Professionals and Programme Managers","author":"WHO","year":"2006"},{"key":"10.1016\/j.actatropica.2018.03.002_bib0210","series-title":"Limination of Schistosomiasis. Report by the Secretariat","author":"WHO","year":"2012"},{"issue":"5","key":"10.1016\/j.actatropica.2018.03.002_bib0215","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/BF00925485","article-title":"Ultrastructural localization of the circulating cathodic antigen in the digestive tract of various life-cycle stages of Schistosoma mansoni","volume":"72","author":"de Water","year":"1986","journal-title":"Z. Parasitenkd."},{"issue":"12","key":"10.1016\/j.actatropica.2018.03.002_bib0220","doi-asserted-by":"crossref","first-page":"5458","DOI":"10.1128\/JCM.42.12.5458-5461.2004","article-title":"Diagnosis of schistosomiasis by reagent strip test for detection of circulating cathodic antigen","volume":"42","author":"van Dam","year":"2004","journal-title":"J. Clin. Microbiol."},{"issue":"PtB","key":"10.1016\/j.actatropica.2018.03.002_bib0225","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.actatropica.2014.09.003","article-title":"Evaluation of banked urine samples for the detection of circulating anodic and cathodic antigens in Schistosoma mekongi and S. japonicum infections: a proof-of-concept study","volume":"141","author":"van Dam","year":"2015","journal-title":"Acta Trop."}],"container-title":["Acta Tropica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X17308690?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X17308690?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:15:11Z","timestamp":1757549711000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001706X17308690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":45,"alternative-id":["S0001706X17308690"],"URL":"https:\/\/doi.org\/10.1016\/j.actatropica.2018.03.002","relation":{},"ISSN":["0001-706X"],"issn-type":[{"value":"0001-706X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluating a point-of-care circulating cathodic antigen test (POC-CCA) to detect Schistosoma mansoni infections in a low endemic area in north-eastern Brazil","name":"articletitle","label":"Article Title"},{"value":"Acta Tropica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actatropica.2018.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}