{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:43:46Z","timestamp":1790189026095,"version":"4.1.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Tropica"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.actatropica.2018.03.016","type":"journal-article","created":{"date-parts":[[2018,3,18]],"date-time":"2018-03-18T11:05:28Z","timestamp":1521371128000},"page":"246-250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"special_numbering":"C","title":["Liposomal amphotericin B treatment of Old World cutaneous and mucosal leishmaniasis: A literature review"],"prefix":"10.1016","volume":"182","author":[{"given":"Vincent","family":"Mosimann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Neumayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel H.","family":"Paris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Blum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.actatropica.2018.03.016_bib0005","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/mmy\/myv111","article-title":"Comparison between liposomal formulations of amphotericin B","volume":"54","author":"Adler-Moore","year":"2016","journal-title":"Med. Mycol."},{"issue":"12","key":"10.1016\/j.actatropica.2018.03.016_bib0010","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1056\/NEJMoa011882","article-title":"Fluconazole for the treatment of cutaneous leishmaniasis caused by Leishmania major","volume":"346","author":"Alrajhi","year":"2002","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.016_bib0015","doi-asserted-by":"crossref","first-page":"e628","DOI":"10.1371\/journal.pntd.0000628","article-title":"A randomized controlled trial of local heat therapy versus intravenous sodium stibogluconate for the treatment of cutaneous Leishmania major infection","volume":"4","author":"Aronson","year":"2010","journal-title":"PLoS. Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0020","doi-asserted-by":"crossref","first-page":"24","DOI":"10.4269\/ajtmh.16-84256","article-title":"Diagnosis and treatment of leishmaniasis: clinical practice guidelines by the infectious diseases society of america (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH)","volume":"96","author":"Aronson","year":"2017","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"4","key":"10.1016\/j.actatropica.2018.03.016_bib0025","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/0035-9203(86)90176-8","article-title":"Failure of meglumine antimoniate to cure cutaneous lesions due to Leishmania-major in Algeria","volume":"80","author":"Belazzoug","year":"1986","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.actatropica.2018.03.016_bib0030","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/jac\/dkh058","article-title":"Treatment of cutaneous leishmaniasis among travellers","volume":"53","author":"Blum","year":"2004","journal-title":"J. Antimicrob. Chemother."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.016_bib0035","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.inhe.2012.06.004","article-title":"Local or systemic treatment for New World cutaneous leishmaniasis? Re-evaluating the evidence for the risk of mucosal leishmaniasis","volume":"4","author":"Blum","year":"2012","journal-title":"Int. Health"},{"issue":"2","key":"10.1016\/j.actatropica.2018.03.016_bib0040","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/jtm.12089","article-title":"LeishMan recommendations for treatment of cutaneous and mucosal leishmaniasis in travelers, 2014","volume":"21","author":"Blum","year":"2014","journal-title":"J. Travel Med."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0045","first-page":"83","article-title":"Two cases of successful treatment of multilesional cutaneous leishmaniasis with liposomal amphotericin B","volume":"11","author":"Butsch","year":"2013","journal-title":"J. Dtsch. Dermatol. Ges."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0050","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/jac\/dkh279","article-title":"A 6 day course of liposomal amphotericin B in the treatment of infantile visceral leishmaniasis: the Italian experience","volume":"54","author":"Cascio","year":"2004","journal-title":"J. Antimicro. Chemother."},{"issue":"6","key":"10.1016\/j.actatropica.2018.03.016_bib0055","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s10654-005-1249-7","article-title":"A rare case of localized mucosal leishmaniasis due to Leishmania infantum in an immunocompetent Italian host","volume":"20","author":"Casolari","year":"2005","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.actatropica.2018.03.016_bib0060","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1186\/s12879-014-0597-x","article-title":"A case of imported Leishmania infantum cutaneous leishmaniasis; an unusual presentation occurring 19 years after travel","volume":"14","author":"Crowe","year":"2014","journal-title":"BMC Infect. Dis."},{"issue":"6","key":"10.1016\/j.actatropica.2018.03.016_bib0065","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.4269\/ajtmh.15-0033","article-title":"Efficacy and safety of liposomal amphotericin B for the treatment of mucosal leishmaniasis from the New World: a retrospective study","volume":"93","author":"Cunha","year":"2015","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"2","key":"10.1016\/j.actatropica.2018.03.016_bib0070","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/tropej\/fmp073","article-title":"Successful treatment of childhood cutaneous leishmaniasis with liposomal amphotericin B: report of two cases","volume":"56","author":"del Rosal","year":"2010","journal-title":"J. Trop. Pediatr."},{"issue":"31\u201332","key":"10.1016\/j.actatropica.2018.03.016_bib0075","first-page":"1601","article-title":"Severe oral mucositis in a patient with HIV infection","volume":"138","author":"Ehlert","year":"2013","journal-title":"Dtsch. Med. Wochenschr."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0080","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jinf.2011.03.012","article-title":"Mucosal Leishmania infantum leishmaniasis: specific pattern in a multicentre survey and historical cases","volume":"63","author":"Faucher","year":"2011","journal-title":"J. Infect."},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.016_bib0085","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/j.1365-4632.2009.04072.x","article-title":"Efficacy of glucantime in the treatment of Old World cutaneous leishmaniasis","volume":"48","author":"Firdous","year":"2009","journal-title":"Int. J. Dermatol."},{"issue":"12","key":"10.1016\/j.actatropica.2018.03.016_bib0090","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1001\/archderm.142.12.1575","article-title":"Imiquimod in combination with meglumine antimoniate for cutaneous leishmaniasis: a randomized assessor-blind controlled trial","volume":"142","author":"Firooz","year":"2006","journal-title":"Arch. Dermatol."},{"issue":"6","key":"10.1016\/j.actatropica.2018.03.016_bib0095","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1590\/0037-8682-0104-2013","article-title":"Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence","volume":"46","author":"Fontenele e Silva","year":"2013","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"2","key":"10.1016\/j.actatropica.2018.03.016_bib0100","doi-asserted-by":"crossref","first-page":"140","DOI":"10.4103\/0972-9062.134825","article-title":"A multidisciplinary approach to an uncommon case of laryngeal leishmaniasis in Turkey","volume":"51","author":"Gokmen","year":"2014","journal-title":"J. Vector Borne Dis."},{"issue":"10","key":"10.1016\/j.actatropica.2018.03.016_bib0105","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/j.humpath.2005.07.006","article-title":"Detection of Leishmania infantum kinetoplast DNA in laryngeal tissue from an immunocompetent patient","volume":"36","author":"Guddo","year":"2005","journal-title":"Hum. Pathol."},{"issue":"11","key":"10.1016\/j.actatropica.2018.03.016_bib0110","doi-asserted-by":"crossref","first-page":"e0006094","DOI":"10.1371\/journal.pntd.0006094","article-title":"Liposomal amphotericin B in travelers with cutaneous and muco-cutaneous leishmaniasis: not a panacea","volume":"11","author":"Guery","year":"2017","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0115","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/INF.0b013e31822dfbf7","article-title":"Old world Leishmania infantum cutaneous leishmaniasis unresponsive to liposomal amphotericin B treated with topical imiquimod","volume":"31","author":"Hervas","year":"2012","journal-title":"Pediatr. Infect. Dis. J."},{"issue":"4","key":"10.1016\/j.actatropica.2018.03.016_bib0120","doi-asserted-by":"crossref","first-page":"597","DOI":"10.4269\/ajtmh.2010.09-0698","article-title":"Leishmaniasis in the tongue of an immunocompetent man","volume":"82","author":"Leitner","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0125","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.parint.2013.10.002","article-title":"Mucocutaneous leishmaniasis as presentation of HIV infection in Sardinia, insular Italy","volume":"63","author":"Madeddu","year":"2014","journal-title":"Parasitol. Int."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0130","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.actatropica.2007.05.005","article-title":"Comparison of miltefosine and meglumine antimoniate for the treatment of zoonotic cutaneous leishmaniasis (ZCL) by a randomized clinical trial in Iran","volume":"103","author":"Mohebali","year":"2007","journal-title":"Acta Trop."},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.016_bib0135","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.1365-4362.2002.01527.x","article-title":"Treatment of cutaneous leishmaniasis with a combination of allopurinol and low-dose meglumine antimoniate","volume":"41","author":"Momeni","year":"2002","journal-title":"Int. J. Dermatol."},{"issue":"4","key":"10.1016\/j.actatropica.2018.03.016_bib0140","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1086\/520017","article-title":"Cutaneous leishmaniasis during pregnancy: exuberant lesions and potential fetal complications","volume":"45","author":"Morgan","year":"2007","journal-title":"Clin. Infect. Dis."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0145","doi-asserted-by":"crossref","first-page":"48","DOI":"10.4269\/ajtmh.2007.76.48","article-title":"Healing of Old World cutaneous leishmaniasis in travelers treated with fluconazole: drug effect or spontaneous evolution?","volume":"76","author":"Morizot","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0150","doi-asserted-by":"crossref","first-page":"e0004304","DOI":"10.1371\/journal.pntd.0004304","article-title":"Antimony to cure visceral leishmaniasis unresponsive to liposomal amphotericin B","volume":"10","author":"Morizot","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0155","doi-asserted-by":"crossref","first-page":"ofw008","DOI":"10.1093\/ofid\/ofw008","article-title":"Miltefosine for mucosal and complicated cutaneous Old World leishmaniasis: a case series and review of the literature","volume":"3","author":"Mosimann","year":"2016","journal-title":"Open Forum Infect. Dis."},{"issue":"2","key":"10.1016\/j.actatropica.2018.03.016_bib0160","first-page":"60","article-title":"Clinical efficacy of intramuscular meglumine antimoniate alone and in combination with intralesional meglumine antimoniate in the treatment of old world cutaneous leishmaniasis","volume":"16","author":"Munir","year":"2008","journal-title":"Acta Dermatovenerol. Croat."},{"key":"10.1016\/j.actatropica.2018.03.016_bib0165","article-title":"Clinical aspects and management of cutaneous leishmaniasis in rheumatoid patients treated with TNF-alpha antagonists","author":"Neumayr","year":"2013","journal-title":"TMAID"},{"issue":"5","key":"10.1016\/j.actatropica.2018.03.016_bib0170","doi-asserted-by":"crossref","first-page":"e261","DOI":"10.1016\/j.jinf.2005.03.012","article-title":"Atypical multifocal cutaneous leishmaniasis in an immunocompetent patient treated by liposomal amphotericin B","volume":"51","author":"Paradisi","year":"2005","journal-title":"J. Infect."},{"issue":"6","key":"10.1016\/j.actatropica.2018.03.016_bib0175","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1708-8305.2009.00341.x","article-title":"Imported leishmaniasis: a heterogeneous group of diseases","volume":"16","author":"Perez-Ayala","year":"2009","journal-title":"J. Travel Med."},{"key":"10.1016\/j.actatropica.2018.03.016_bib0180","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1186\/1471-2334-6-177","article-title":"Leishmania infantum leishmaniasis in corticosteroid? Treated patients","author":"Pittalis","year":"2006","journal-title":"BMC Infect. Dis."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.016_bib0185","first-page":"209","article-title":"Liposomal amphotericin B treatment of cutaneous leishmaniasis contracted in Djibouti and resistant to meglumine antimoniate","volume":"96","author":"Rapp","year":"2003","journal-title":"Bull. Soc. Pathol. Exot."},{"issue":"8","key":"10.1016\/j.actatropica.2018.03.016_bib0190","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1086\/428736","article-title":"Efficacy of thermotherapy to treat cutaneous leishmaniasis caused by Leishmania tropica in Kabul, Afghanistan : a randomized, controlled trial","volume":"40","author":"Reithinger","year":"2005","journal-title":"Clin. Infect. Dis."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.016_bib0195","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1007\/s00436-011-2356-x","article-title":"Mucosal leishmania infantum infection","volume":"109","author":"Richter","year":"2011","journal-title":"Parasitol. Res."},{"issue":"3","key":"10.1016\/j.actatropica.2018.03.016_bib0200","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1093\/trstmh\/tru011","article-title":"Liposomal formulation of amphotericin B for the treatment of mucosal leishmaniasis in HIV-negative patients","volume":"108","author":"Rocio","year":"2014","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"issue":"7","key":"10.1016\/j.actatropica.2018.03.016_bib0205","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/j.1365-4632.2006.02867.x","article-title":"Effect of combination therapy with systemic glucantime and pentoxifylline in the treatment of cutaneous leishmaniasis","volume":"45","author":"Sadeghian","year":"2006","journal-title":"Int. J. Dermatol."},{"issue":"8","key":"10.1016\/j.actatropica.2018.03.016_bib0210","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1111\/j.1468-3083.2010.03908.x","article-title":"Liposomal amphotericin B treatment of cutaneous leishmaniasis due to Leishmania tropica","volume":"25","author":"Solomon","year":"2011","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"issue":"1","key":"10.1016\/j.actatropica.2018.03.016_bib0215","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.actatropica.2013.07.002","article-title":"Treatment of mucosal leishmaniasis (L. infantum) with miltefosine in a patient with Good syndrome","volume":"128","author":"Stoeckle","year":"2013","journal-title":"Acta Trop."},{"issue":"8","key":"10.1016\/j.actatropica.2018.03.016_bib0220","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1086\/591972","article-title":"New treatment approach in Indian visceral leishmaniasis: single-dose liposomal amphotericin B followed by short-course oral miltefosine","volume":"47","author":"Sundar","year":"2008","journal-title":"Clin. Infect. Dis."},{"issue":"4","key":"10.1016\/j.actatropica.2018.03.016_bib0225","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/1469-0691.12556","article-title":"Leishmaniasis in immunosuppressed individuals","volume":"20","author":"van Griensven","year":"2014","journal-title":"Clin. Microbiol. Infect."},{"issue":"6","key":"10.1016\/j.actatropica.2018.03.016_bib0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001688","article-title":"Monitoring toxicity associated with parenteral sodium stibogluconate in the day-case management of returned travellers with new world cutaneous leishmaniasis","volume":"6","author":"Wise","year":"2012","journal-title":"Plos Negl. Trop. Dis."},{"issue":"5","key":"10.1016\/j.actatropica.2018.03.016_bib0235","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.4269\/ajtmh.2010.10-0171","article-title":"Lipsosomal amphotericin B for treatment of cutaneous leishmaniasis","volume":"83","author":"Wortmann","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"5","key":"10.1016\/j.actatropica.2018.03.016_bib0240","doi-asserted-by":"crossref","first-page":"692","DOI":"10.4269\/ajtmh.2011.10-0712","article-title":"Case report: successful treatment of cutaneous leishmaniasis caused by Leishmania aethiopica with liposomal amphothericin B in an immunocompromised traveler returning from Eritrea","volume":"84","author":"Zanger","year":"2011","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"8","key":"10.1016\/j.actatropica.2018.03.016_bib0245","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1046\/j.1365-4362.1999.00727.x","article-title":"A double-blind randomized clinical trial of a topical herbal extract (Z-HE) vs systemic meglumine antimoniate for the treatment of cutaneous leishmaniasis in Iran","volume":"38","author":"Zerehsaz","year":"1999","journal-title":"Int. J. Dermatol."}],"container-title":["Acta Tropica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X17313517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0001706X17313517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:14:18Z","timestamp":1757549658000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0001706X17313517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":49,"alternative-id":["S0001706X17313517"],"URL":"https:\/\/doi.org\/10.1016\/j.actatropica.2018.03.016","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.732870066.793580942","asserted-by":"object"}]},"ISSN":["0001-706X"],"issn-type":[{"value":"0001-706X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liposomal amphotericin B treatment of Old World cutaneous and mucosal leishmaniasis: A literature review","name":"articletitle","label":"Article Title"},{"value":"Acta Tropica","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actatropica.2018.03.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}