{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:18:37Z","timestamp":1789154317910,"version":"build-2803163510"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.actbio.2015.06.015","type":"journal-article","created":{"date-parts":[[2015,6,16]],"date-time":"2015-06-16T02:50:27Z","timestamp":1434423027000},"page":"193-200","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Characterisation of the fatigue life, dynamic creep and modes of damage accumulation within mitral valve chordae tendineae"],"prefix":"10.1016","volume":"24","author":[{"given":"Gillian M.","family":"Gunning","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce P.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2015.06.015_b0005","first-page":"e28","article-title":"Heart disease and stroke statistics\u20132014 update: a report from the American Heart Association","volume":"129","author":"Go","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2015.06.015_b0010","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/S0140-6736(09)60692-9","article-title":"Mitral regurgitation","volume":"373","author":"Enriquez-Sarano","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.actbio.2015.06.015_b0015","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ijcard.2010.02.011","article-title":"The underlying causes of chordae tendinae rupture: a systematic review","volume":"143","author":"Gabbay","year":"2010","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.actbio.2015.06.015_b0020","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.ijcard.2012.04.092","article-title":"Structural analysis of chordae tendineae in degenerative disease of the mitral valve","volume":"167","author":"Icardo","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.actbio.2015.06.015_b0025","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1136\/hrt.50.4.312","article-title":"Chordal rupture. I: aetiology and natural history","volume":"50","author":"Oliveira","year":"1983","journal-title":"Br. Heart J."},{"key":"10.1016\/j.actbio.2015.06.015_b0030","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/path.1711330303","article-title":"Ultrastructural changes in spontaneous rupture of mitral chordae tendineae","volume":"133","author":"Scott-Jupp","year":"1981","journal-title":"J. Pathol."},{"key":"10.1016\/j.actbio.2015.06.015_b0035","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/S0735-1097(85)80346-6","article-title":"Primary (spontaneous) chordal rupture: relation to myxomatous valve disease and mitral valve prolapse","volume":"5","author":"Hickey","year":"1985","journal-title":"J. Am. College Cardiol."},{"issue":"Pt 4","key":"10.1016\/j.actbio.2015.06.015_b0040","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1046\/j.1469-7580.1998.19240573.x","article-title":"Structure of chordae tendineae in the left ventricle of the human heart","volume":"192","author":"Millington-Sanders","year":"1998","journal-title":"J. Anat."},{"key":"10.1016\/j.actbio.2015.06.015_b0045","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1161\/01.RES.39.4.580","article-title":"Morphology and relationship to extensibility curves of human mitral valve chordae tendineae","volume":"39","author":"Lim","year":"1976","journal-title":"Circ. Res."},{"key":"10.1016\/j.actbio.2015.06.015_b0050","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.athoracsur.2005.02.011","article-title":"Structural characterization of the chordae tendineae in native porcine mitral valves","volume":"80","author":"Ritchie","year":"2005","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.actbio.2015.06.015_b0055","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/S0021-9290(03)00109-X","article-title":"A structural basis for the size-related mechanical properties of mitral valve chordae tendineae","volume":"36","author":"Liao","year":"2003","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2015.06.015_b0060","first-page":"345","article-title":"Aging changes in the aortic and mitral valves. histologic and histochemical studies, with observations on the pathogenesis of calcific aortic stenosis and calcification of the mitral annulus","volume":"46","author":"Sell","year":"1965","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.actbio.2015.06.015_b0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jmbbm.2012.03.016","article-title":"Determination of the mechanical properties of normal and calcified human mitral chordae tendineae","volume":"13","author":"Casado","year":"2012","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2015.06.015_b0070","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jbiomech.2005.12.011","article-title":"Skewness angle of interfibrillar proteoglycans increases with applied load on mitral valve chordae tendineae","volume":"40","author":"Liao","year":"2007","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2015.06.015_b0075","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1139\/y75-048","article-title":"Mechanical properties of human mitral valve chordae tendineae: variation with size and strain rate","volume":"53","author":"Lim","year":"1975","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.actbio.2015.06.015_b0080","first-page":"M405","article-title":"Mechanical properties of basal and marginal mitral valve chordae tendineae","volume":"36","author":"Kunzelman","year":"1990","journal-title":"ASAIO Trans."},{"key":"10.1016\/j.actbio.2015.06.015_b0085","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.jbiomech.2005.01.024","article-title":"The material properties of the native porcine mitral valve chordae tendineae: an in vitro investigation","volume":"39","author":"Ritchie","year":"2006","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2015.06.015_b0090","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s10439-013-0908-1","article-title":"Mitral valve repair using ePTFE sutures for ruptured mitral chordae tendineae: a computational simulation study","volume":"42","author":"Rim","year":"2014","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.actbio.2015.06.015_b0095","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s13239-014-0175-9","article-title":"Quantitative evaluation of annuloplasty on mitral valve chordae tendineae forces to supplement surgical planning model development","volume":"5","author":"Siefert","year":"2014","journal-title":"Cardiovasc Eng. Technol."},{"key":"10.1016\/j.actbio.2015.06.015_b0100","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s10237-007-0116-8","article-title":"Finite element analysis of the mitral apparatus: annulus shape effect and chordal force distribution","volume":"8","author":"Prot","year":"2009","journal-title":"Biomech. Model Mechanobiol."},{"key":"10.1016\/j.actbio.2015.06.015_b0105","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jbiomech.2013.11.035","article-title":"Determination of the tensile mechanical properties of the segmented mitral valve annulus","volume":"47","author":"Gunning","year":"2014","journal-title":"J Biomech."},{"key":"10.1016\/j.actbio.2015.06.015_b0110","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1142\/S0219519411003971","article-title":"Mechanical properties of chordae tendineae of the mitral heart valve: Young\u2019s modulus, structural stiffness, and effects of aging","volume":"11","author":"Millard","year":"2011","journal-title":"J. Mech. Med. Biol."},{"key":"10.1016\/j.actbio.2015.06.015_b0115","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1006\/phrs.1999.0651","article-title":"Experimental models for the study of cardiovascular function and disease","volume":"41","author":"Hearse","year":"2000","journal-title":"Pharmacol. Res."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706115002810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706115002810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T16:45:44Z","timestamp":1761669944000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706115002810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":23,"alternative-id":["S1742706115002810"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2015.06.015","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterisation of the fatigue life, dynamic creep and modes of damage accumulation within mitral valve chordae tendineae","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2015.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}