{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T13:14:15Z","timestamp":1767964455675,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.actbio.2019.07.050","type":"journal-article","created":{"date-parts":[[2019,7,30]],"date-time":"2019-07-30T13:46:43Z","timestamp":1564494403000},"page":"239-246","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Backside wear, particle migration and effectiveness of screw hole plugs in acetabular hip joint replacement with cross-linked polyethylene"],"prefix":"10.1016","volume":"97","author":[{"given":"Steffen","family":"Braun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirin","family":"Vardag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Schroeder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1809-7528","authenticated-orcid":false,"given":"Robert","family":"Sonntag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Therese","family":"Bormann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Gotterbarm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Philippe","family":"Kretzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2019.07.050_b0005","unstructured":"ISO 14242-1, Implants for surgery \u2013 Wear of total hip-joint prosthese \u2013 Part1: Loading and displacement parameters for wear-testing machines and corresponding environment conditions for test: Geneva, Switzerland: International Organization of Standardization., (2014)."},{"key":"10.1016\/j.actbio.2019.07.050_b0010","unstructured":"ISO 14242-2, Implants for surgery \u2013 Wear of total hip-joint protheses \u2013 Part 2: Methods of measurent. Geneva, Switzerland: International Organisation of Standardization (2016)."},{"key":"10.1016\/j.actbio.2019.07.050_b0015","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jmbbm.2016.08.003","article-title":"Wear performance of neat and vitamin E blended highly cross-linked PE under severe conditions: the combined effect of accelerated ageing and third body particles during wear test","volume":"64","author":"Affatato","year":"2016","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2019.07.050_b0020","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1007\/s11999-015-4422-7","article-title":"Low wear rates seen in THAs with highly crosslinked polyethylene at 9 to 14 years in patients younger than age 50 years","volume":"473","author":"Garvin","year":"2015","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0025","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/j.arth.2012.12.020","article-title":"Wear comparison between conventional and highly cross-linked polyethylene against a zirconia head: a concise follow-up, at an average 10 years, of a previous report","volume":"28","author":"Fukui","year":"2013","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0030","first-page":"182","article-title":"Biologic effects of implant debris","volume":"67","author":"Hallab","year":"2009","journal-title":"Bull NYU Hosp Jt Dis."},{"key":"10.1016\/j.actbio.2019.07.050_b0035","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/01.blo.0000238813.95035.1b","article-title":"The cellular and molecular biology of periprosthetic osteolysis","volume":"454","author":"Purdue","year":"2007","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0040","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s10787-013-0192-6","article-title":"Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management","volume":"21","author":"Howie","year":"2013","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.actbio.2019.07.050_b0045","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1054\/arth.2002.33664","article-title":"A literature review of the association between wear rate and osteolysis in total hip arthroplasty","volume":"17","author":"Dumbleton","year":"2002","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0050","article-title":"Wear and periprosthetic osteolysis: the problem","volume":"66\u201370","author":"Harris","year":"2001","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0055","unstructured":"J. Kaerrholm, M. Mohaddes, D. Odin, C. Rogmark, O. Rolfson, Swedish Hip Arthroplasty Register \u2013 Annual Report 2017, (2017)."},{"key":"10.1016\/j.actbio.2019.07.050_b0060","unstructured":"A. Grimberg, V. Jansson, T. Liebs, O. Melsheimer, A. Siebert, Endoprothesenregister Deutschland (EPRD) \u2013 Jahresbericht 2017, (2017)."},{"key":"10.1016\/j.actbio.2019.07.050_b0065","unstructured":"S. Graves, R. de Steiger, L. Lewis, I. Harris, Hip, Knee & Shoulder Arthroplasty \u2013 Annual Report 2018, Australian Orthopaedic Association National Joint Replacement Registry. (2018)."},{"key":"10.1016\/j.actbio.2019.07.050_b0070","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1302\/0301-620X.76B4.8027142","article-title":"Polyethylene and metal debris generated by non-articulating surfaces of modular acetabular components","volume":"76","author":"Huk","year":"1994","journal-title":"J. Bone Joint Surg. Br."},{"key":"10.1016\/j.actbio.2019.07.050_b0075","doi-asserted-by":"crossref","first-page":"29","DOI":"10.21823\/2311-2905-2018-24-2-29-40","article-title":"Articulation and backside wear analysis after long-term in vitro wear simulation of vitamin e stabilized polyethylene acetabular liners with a press-fit locking mechanism","volume":"24","author":"Puente Reyna","year":"2018","journal-title":"Traumatol. Orthopedics Russ."},{"key":"10.1016\/j.actbio.2019.07.050_b0080","article-title":"Backside wear is not dependent on the acetabular socket design in crosslinked polyethylene liners","author":"Bali","year":"2015","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0085","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.arth.2010.07.012","article-title":"Minimal backside surface changes observed in retrieved acetabular liners","volume":"26","author":"Akbari","year":"2011","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0090","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/01.blo.0000177719.16146.33","article-title":"Backside wear is low in retrieved modern, modular, and nonmodular acetabular liners","volume":"440","author":"Della Valle","year":"2005","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0095","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.arth.2005.04.033","article-title":"The acetabular insert-metal backing interface: an additional source of polyethylene wear debris","volume":"20","author":"Wasielewski","year":"2005","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0100","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1002\/jbm.820170510","article-title":"Retrieval analysis of total knee prostheses: a method and its application to 48 total condylar prostheses","volume":"17","author":"Hood","year":"1983","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0105","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.actbio.2018.10.045","article-title":"Backside wear in acetabular hip joint replacement","volume":"83","author":"Braun","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.07.050_b0110","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1302\/0301-620X.91B8.21850","article-title":"Backside volumetric change in the polyethylene of uncemented acetabular components","volume":"91","author":"Krieg","year":"2009","journal-title":"J. Bone Joint Surg. Br."},{"key":"10.1016\/j.actbio.2019.07.050_b0115","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0021-9290(99)00043-3","article-title":"Simulation of initial frontside and backside wear rates in a modular acetabular component with multiple screw holes","volume":"32","author":"Kurtz","year":"1999","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2019.07.050_b0120","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jmbbm.2014.01.005","article-title":"Periprosthetic wear particle migration and distribution modelling and the implication for osteolysis in cementless total hip replacement","volume":"32","author":"Alidousti","year":"2014","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2019.07.050_b0125","doi-asserted-by":"crossref","first-page":"677","DOI":"10.2106\/00004623-199405000-00008","article-title":"The relationship between the design, position, and articular wear of acetabular components inserted without cement and the development of pelvic osteolysis","volume":"76","author":"Schmalzried","year":"1994","journal-title":"J. Bone Joint Surg. Am."},{"key":"10.1016\/j.actbio.2019.07.050_b0130","doi-asserted-by":"crossref","first-page":"849","DOI":"10.2106\/00004623-199274060-00006","article-title":"Periprosthetic bone loss in total hip arthroplasty. Polyethylene wear debris and the concept of the effective joint space","volume":"74","author":"Schmalzried","year":"1992","journal-title":"J Bone Joint Surg Am."},{"key":"10.1016\/j.actbio.2019.07.050_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.arth.2009.08.021","article-title":"Extensive osteolysis caused by polyethylene particle migration in an anatomical hydroxyapatite-coated hip prosthesis: 10 years' follow-up","volume":"25","author":"Canales","year":"2010","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0140","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0883-5403(98)90169-3","article-title":"Effect of locking mechanism on fluid and particle flow through modular acetabular components","volume":"13","author":"Khalily","year":"1998","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0145","article-title":"Osteolysis around uncemented acetabular components of cobalt-chrome surface replacement hip arthroplasty","volume":"202\u2013211","author":"Buechel","year":"1994","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0150","doi-asserted-by":"crossref","first-page":"3771","DOI":"10.1016\/j.arth.2017.06.047","article-title":"Highly Cross-Linked Polyethylene Reduces Osteolysis Incidence and Wear-Related Reoperation Rate in Cementless Total Hip Arthroplasty Compared With Conventional Polyethylene at a Mean 12-Year Follow-Up","volume":"32","author":"Tsukamoto","year":"2017","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0155","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1016\/j.arth.2017.05.030","article-title":"Osteoclasts in Periprosthetic Osteolysis: The Charnley Arthroplasty Revisited","volume":"32","author":"Mukka","year":"2017","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0160","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.2106\/JBJS.J.01507","article-title":"Successful long-term fixation and progression of osteolysis associated with first-generation cementless acetabular components retrieved post mortem","volume":"94","author":"Urban","year":"2012","journal-title":"J. Bone Joint Surg. Am."},{"key":"10.1016\/j.actbio.2019.07.050_b0165","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1007\/s11999-009-0756-3","article-title":"Patient activity after total hip arthroplasty declines with advancing age","volume":"467","author":"Kinkel","year":"2009","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0170","unstructured":"ASTM F1877-16, Standard Practice for Characterization of Particles. West Conshohocken, USA: American Society for Testing and Materials, (2010)."},{"key":"10.1016\/j.actbio.2019.07.050_b0175","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1002\/jbm.a.10088","article-title":"Size, shape, and composition of wear particles from metal-metal hip simulator testing: effects of alloy and number of loading cycles","volume":"67","author":"Catelas","year":"2003","journal-title":"J. Biomed. Mater. Res. A"},{"key":"10.1016\/j.actbio.2019.07.050_b0180","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1007\/s10856-014-5271-8","article-title":"How do gait frequency and serum-replacement interval affect polyethylene wear in knee-wear simulator tests?","volume":"25","author":"Reinders","year":"2014","journal-title":"J. Mater. Sci. \u2013 Mater. Med."},{"key":"10.1016\/j.actbio.2019.07.050_b0185","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1007\/s10856-013-4936-z","article-title":"Wear testing and particle characterisation of sequentially crosslinked polyethylene acetabular liners using different femoral head sizes","volume":"24","author":"Zietz","year":"2013","journal-title":"J. Mater. Sci. \u2013 Mater. Med."},{"key":"10.1016\/j.actbio.2019.07.050_b0190","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1177\/0954411916628559","article-title":"Measurement outcomes from hip simulators","volume":"230","author":"de Villiers","year":"2016","journal-title":"Proc. Inst. Mech. Eng. H."},{"key":"10.1016\/j.actbio.2019.07.050_b0195","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1302\/0301-620X.95B3.29456","article-title":"New polyethylenes in total hip replacement: A ten- to 12-year follow-up study","volume":"95-b","author":"Garcia-Rey","year":"2013","journal-title":"Bone Joint J."},{"key":"10.1016\/j.actbio.2019.07.050_b0200","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.arth.2007.05.043","article-title":"Highly crosslinked vs conventional polyethylene particles\u2013an in vitro comparison of biologic activities","volume":"23","author":"Illgen","year":"2008","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0205","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.arth.2008.01.134","article-title":"Highly crosslinked vs conventional polyethylene particles: relative in vivo inflammatory response","volume":"24","author":"Illgen","year":"2009","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.actbio.2019.07.050_b0210","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/jor.1100180322","article-title":"Pressure-induced periprosthetic osteolysis: a rat model","volume":"18","author":"Skripitz","year":"2000","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0215","article-title":"Fluid pressure causes bone resorption in a rabbit model of prosthetic loosening","volume":"201\u2013208","author":"Van der Vis","year":"1998","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.actbio.2019.07.050_b0220","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/jbm.b.30213","article-title":"Particle analysis for the determination of UHMWPE wear","volume":"73","author":"Scott","year":"2005","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706119305392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706119305392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:23:52Z","timestamp":1761672232000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706119305392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":44,"alternative-id":["S1742706119305392"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2019.07.050","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Backside wear, particle migration and effectiveness of screw hole plugs in acetabular hip joint replacement with cross-linked polyethylene","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2019.07.050","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}