{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:28:49Z","timestamp":1790299729292,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:00:00Z","timestamp":1578268800000},"content-version":"vor","delay-in-days":66,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000853","name":"University of Glasgow","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000853","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.actbio.2019.08.038","type":"journal-article","created":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T19:34:54Z","timestamp":1566848094000},"page":"443-456","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Failure properties and microstructure of healthy and aneurysmatic human thoracic aortas subjected to uniaxial extension with a focus on the media"],"prefix":"10.1016","volume":"99","author":[{"given":"Selda","family":"Sherifova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Sommer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Viertler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Regitnig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Caranasos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret Anne","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyce E.","family":"Griffith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray W.","family":"Ogden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard A.","family":"Holzapfel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2006","key":"10.1016\/j.actbio.2019.08.038_b0005","first-page":"2611","article-title":"Thoracic aortic aneurysm and dissection: increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14,000 cases from to 2002","volume":"114","author":"Olsson","year":"1987","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2019.08.038_b0010","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.athoracsur.2007.10.099","article-title":"Society of Thoracic Surgeons Endovascular Surgery Task Force, Expert consensus document on the treatment of descending thoracic aortic disease using endovascular stent-grafts","volume":"85","author":"Svensson","year":"2008","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.actbio.2019.08.038_b0015","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jacc.2015.05.029","article-title":"Presentation diagnosis, and outcomes of acute aortic dissection: 17-year trends from the international registry of acute aortic dissection","volume":"66","author":"Pape","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.actbio.2019.08.038_b0020","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1056\/NEJMoa012573","article-title":"Aneurysm Detection and Management Veterans Affairs Cooperative Study Group, Immediate repair compared with surveillance of small abdominal aortic aneurysms","volume":"346","author":"Lederle","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.actbio.2019.08.038_b0025","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1136\/jme.2004.009803","article-title":"Implant ethics","volume":"31","author":"Hansson","year":"2005","journal-title":"J. Med. Ethics"},{"key":"10.1016\/j.actbio.2019.08.038_b0030","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ejvs.2009.05.004","article-title":"Epidemiology, aetiology, risk of rupture and treatment of abdominal aortic aneurysms: does sex matter?","volume":"38","author":"Grootenboer","year":"2009","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"10.1016\/j.actbio.2019.08.038_b0035","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1161\/CIRCULATIONAHA.114.015177","article-title":"Risk of rupture or dissection in descending thoracic aortic aneurysm","volume":"132","author":"Kim","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2019.08.038_b0040","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1161\/CIRCULATIONAHA.107.702720","article-title":"International Registry of Acute Aortic Dissection (IRAD) Investigators, Aortic diameter > or = 5.5 cm is not a good predictor of type A aortic dissection: Observations from the International Registry of Acute Aortic Dissection (IRAD)","volume":"116","author":"Pape","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2019.08.038_b0045","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.carpath.2008.01.001","article-title":"Local mechanical and structural properties of healthy and diseased human ascending aorta tissue","volume":"18","author":"Choudhury","year":"2009","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.actbio.2019.08.038_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1023\/A:1010835316564","article-title":"A new constitutive framework for arterial wall mechanics and a comparative study of material models","volume":"61","author":"Holzapfel","year":"2000","journal-title":"J. Elasticity"},{"key":"10.1016\/j.actbio.2019.08.038_b0055","doi-asserted-by":"crossref","first-page":"H2048","DOI":"10.1152\/ajpheart.00934.2004","article-title":"Determination of layer-specific mechanical properties of human coronary arteries with non-atherosclerotic intimal thickening, and related constitutive modeling","volume":"289","author":"Holzapfel","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.actbio.2019.08.038_b0060","first-page":"323","article-title":"Mechanical properties of the aorta: a review","volume":"17","author":"Silver","year":"1989","journal-title":"Crit. Rev. Biomed. Eng."},{"key":"10.1016\/j.actbio.2019.08.038_b0065","first-page":"26","article-title":"Structure of the elastin-contractile units in the thoracic aorta and how genes that cause thoracic aortic aneurysms and dissections disrupt this structure","volume":"32","author":"Karimi","year":"2016","journal-title":"Canad. J. Cardiol."},{"key":"10.1016\/j.actbio.2019.08.038_b0070","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.matbio.2007.10.008","article-title":"The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imaging","volume":"27","author":"O\u2019Connell","year":"2008","journal-title":"Matrix Biol."},{"key":"10.1016\/j.actbio.2019.08.038_b0075","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/B978-0-12-363709-3.50012-7","article-title":"Localization of collagen types in tissues","volume":"9","author":"von der Mark","year":"1981","journal-title":"Int. Rev. Conn. Tiss. Res."},{"key":"10.1016\/j.actbio.2019.08.038_b0080","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1098\/rsif.2011.0727","article-title":"Determination of the layer-specific distributed collagen fiber orientations in human thoracic and abdominal aortas and common iliac arteries","volume":"9","author":"Schriefl","year":"2012","journal-title":"J.R. Soc. Interface"},{"key":"10.1016\/j.actbio.2019.08.038_b0085","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1007\/BF02158989","article-title":"Medionecrosis aortae idiopathica","volume":"273","author":"Erdheim","year":"1929","journal-title":"Virch. Arch. Pathol. Anat."},{"key":"10.1016\/j.actbio.2019.08.038_b0090","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.forsciint.2011.07.006","article-title":"Aortic dissecting aneurysms \u2013 histopathological findings","volume":"214","author":"Bode-J\u00e4nisch","year":"2012","journal-title":"Forensic. Sci. Int."},{"key":"10.1016\/j.actbio.2019.08.038_b0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000342436","article-title":"Possible mechanical roles of glycosaminoglycans in thoracic aortic dissection and associations with dysregulated transforming growth factor-\u03b2","volume":"50","author":"Humphrey","year":"2013","journal-title":"J. Vasc. Res."},{"key":"10.1016\/j.actbio.2019.08.038_b0100","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.jss.2013.06.007","article-title":"Molecular mechanisms of thoracic aortic dissection","volume":"184","author":"Wu","year":"2013","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.actbio.2019.08.038_b0105","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000356296","article-title":"Why do aortas cleave or dilate? Clues from an electronic scanning microscopy study in human ascending aortas","volume":"51","author":"Borges","year":"2014","journal-title":"J. Vasc. Res."},{"key":"10.1016\/j.actbio.2019.08.038_b0110","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.2353\/ajpath.2009.081141","article-title":"Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling","volume":"175","author":"Jones","year":"2009","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.actbio.2019.08.038_b0115","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.humpath.2007.08.003","article-title":"Collagen is reduced and disrupted in human aneurysms and dissections of ascending aorta","volume":"39","author":"Borges","year":"2008","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.actbio.2019.08.038_b0120","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.105.000240","article-title":"Increased collagen deposition and elevated expression of connective tissue growth factor in human thoracic aortic dissection","volume":"114","author":"Wang","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.actbio.2019.08.038_b0125","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.jvs.2010.11.035","article-title":"Differential expression of elastin assembly genes in patients with Stanford Type A aortic dissection using microarray analysis","volume":"53","author":"Cheuk","year":"2011","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.actbio.2019.08.038_b0130","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1016\/j.jvs.2012.05.084","article-title":"Association of smooth muscle cell phenotypes with extracellular matrix disorders in thoracic aortic dissection","volume":"56","author":"Wang","year":"2012","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.actbio.2019.08.038_b0135","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1115\/1.1800557","article-title":"Anisotropic mechanical properties of tissue components in human atherosclerotic plaques","volume":"126","author":"Holzapfel","year":"2004","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.actbio.2019.08.038_b0140","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.actbio.2018.05.043","article-title":"Mechanical response of human subclavian and iliac arteries to extension, inflation and torsion","volume":"75","author":"Sommer","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.08.038_b0145","doi-asserted-by":"crossref","first-page":"9036","DOI":"10.1016\/j.actbio.2013.06.011","article-title":"Multiaxial mechanical properties and constitutive modeling of human adipose tissue: a basis for preoperative simulations in plastic and reconstructive surgery","volume":"9","author":"Sommer","year":"2013","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.08.038_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.actbio.2013.07.041","article-title":"Multiaxial mechanical response and constitutive modeling of esophageal tissues: impact on esophageal tissue engineering","volume":"9","author":"Sommer","year":"2013","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.08.038_b0155","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1016\/j.jbiomech.2016.02.042","article-title":"Mechanical strength of aneurysmatic and dissected human thoracic aortas at different shear loading modes","volume":"49","author":"Sommer","year":"2016","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2019.08.038_b0160","doi-asserted-by":"crossref","first-page":"20120760","DOI":"10.1098\/rsif.2012.0760","article-title":"An automated approach for three-dimensional quantification of fibrillar structures in optically cleared soft biological tissues","volume":"10","author":"Schriefl","year":"2013","journal-title":"J.R. Soc. Interface"},{"key":"10.1016\/j.actbio.2019.08.038_b0165","doi-asserted-by":"crossref","first-page":"20150188","DOI":"10.1098\/rsif.2015.0188","article-title":"Modelling non-symmetric collagen fibre dispersion in arterial walls","volume":"12","author":"Holzapfel","year":"2015","journal-title":"J.R. Soc. Interface"},{"key":"10.1016\/j.actbio.2019.08.038_b0170","series-title":"Molecular Biology of the Cell","author":"Alberts","year":"2015"},{"key":"10.1016\/j.actbio.2019.08.038_b0175","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0021-9290(82)90055-0","article-title":"Failure properties of passive human aortic tissue. I \u2013 uniaxial tension tests","volume":"15","author":"Mohan","year":"1982","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2019.08.038_b0180","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/S0003-4975(02)04711-2","article-title":"Effect of aneurysm on the tensile strength and biomechanical behavior of the ascending thoracic aorta","volume":"800","author":"Vorp","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.actbio.2019.08.038_b0185","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s11517-012-0876-x","article-title":"Mechanical behaviour and rupture of normal and pathological human ascending aortic wall","volume":"50","author":"Garc\u00eda-Herrera","year":"2012","journal-title":"Med. Biol. Eng. Comput."},{"key":"10.1016\/j.actbio.2019.08.038_b0190","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1016\/j.athoracsur.2013.07.001","article-title":"Differential tensile strength and collagen composition in ascending aortic aneurysms by aortic valve phenotype","volume":"96","author":"Pichamuthu","year":"2013","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.actbio.2019.08.038_b0195","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jmbbm.2015.08.021","article-title":"Human dilated ascending aorta: Mechanical characterization via uniaxial tensile tests","volume":"53","author":"Ferrara","year":"2016","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2019.08.038_b0200","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.actbio.2017.11.052","article-title":"Detection and characterization of molecular-level collagen damage in overstretched cerebral arteries","volume":"67","author":"Converse","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.08.038_b0205","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jmbbm.2019.04.022","article-title":"Molecular-level collagen damage explains softening and failure of arterial tissues: a quantitative interpretation of CHP data with a novel elasto-damage model","volume":"97","author":"Marino","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2019.08.038_b0210","doi-asserted-by":"crossref","first-page":"20160620","DOI":"10.1098\/rsif.2016.0620","article-title":"Microstructure and mechanics of healthy and aneurysmatic abdominal aortas: experimental analysis and modeling","volume":"13","author":"Niestrawska","year":"2016","journal-title":"J.R. Soc. Interface"},{"key":"10.1016\/j.actbio.2019.08.038_b0215","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1097\/HJH.0000000000000550","article-title":"Large artery stiffness and hypertension after antiangiogenic drugs: influence on cancer progression","volume":"33","author":"Alivon","year":"2015","journal-title":"J. Hypertension"},{"key":"10.1016\/j.actbio.2019.08.038_b0220","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/imj.12645","article-title":"Early and late changes in markers of aortic stiffness with breast cancer therapy","volume":"45","author":"Grover","year":"2015","journal-title":"Intern. Med. J."},{"key":"10.1016\/j.actbio.2019.08.038_b0225","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.2147\/OTT.S126852","article-title":"Arterial stiffness in hematologic malignancies","volume":"10","author":"Mozos","year":"2017","journal-title":"OncoTargets Ther."},{"key":"10.1016\/j.actbio.2019.08.038_b0230","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.ejcts.2008.03.069","article-title":"Regional wall mechanics and blunt traumatic aortic rupture at the isthmus","volume":"34","author":"Pearson","year":"2008","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.actbio.2019.08.038_b0235","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.jmbbm.2017.11.032","article-title":"Tensile rupture of medial arterial tissue studied by X-ray micro-tomography on stained samples","volume":"78","author":"Helfenstein-Didier","year":"2018","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2019.08.038_b0240","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0021-9290(87)90268-5","article-title":"Factors in the propagation of aortic dissection in canine thoracic aortas","volume":"20","author":"van Baardwijk","year":"1987","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2019.08.038_b0245","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0021-9290(90)90050-D","article-title":"The strength of the aortic media and its role in the propagation of aortic dissection","volume":"23","author":"Carson","year":"1990","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2019.08.038_b0250","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1007\/s13239-011-0056-4","article-title":"The influence of medial substructures on rupture in bovine aortas","volume":"2","author":"Haslach","year":"2011","journal-title":"Cardiovasc. Eng. Technol."},{"key":"10.1016\/j.actbio.2019.08.038_b0255","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s13239-015-0245-7","article-title":"Crack propagation and its shear mechanisms in the bovine descending aorta","volume":"6","author":"Haslach","year":"2015","journal-title":"Cardiovasc. Eng. Technol."},{"key":"10.1016\/j.actbio.2019.08.038_b0260","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.actbio.2017.12.027","article-title":"Fracture mechanics of shear crack propagation and dissection in the healthy bovine descending aortic media","volume":"68","author":"Haslach","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.08.038_b0265","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jmbbm.2019.03.028","article-title":"A combined experimental-numerical lamellar-scale approach of tensile rupture in arterial medial tissue using X-ray tomography","volume":"95","author":"Brunet","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.actbio.2019.08.038_b0270","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/0011-2240(88)90024-7","article-title":"Manifestations of cell damage after freezing and thawing","volume":"25","author":"McGann","year":"1988","journal-title":"Cryobiology"},{"key":"10.1016\/j.actbio.2019.08.038_b0275","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1016\/j.jbiomech.2007.04.010","article-title":"Effects of freezing rates and dimethyl sulfoxide concentrations on thermal expansion of rabbit aorta during freezing phase change as measured by thermo mechanical analysis","volume":"40","author":"Xu","year":"2007","journal-title":"J. Biomech."},{"key":"10.1016\/j.actbio.2019.08.038_b0280","doi-asserted-by":"crossref","first-page":"97","DOI":"10.4161\/org.5.3.9495","article-title":"Cryopreservation of vascular tissues","volume":"5","author":"M\u00fcller-Schweinitzer","year":"2009","journal-title":"Organogenesis"},{"key":"10.1016\/j.actbio.2019.08.038_b0285","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jss.2006.09.001","article-title":"Mechanics of fresh, refrigerated, and frozen arterial tissue","volume":"139","author":"Stemper","year":"2007","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.actbio.2019.08.038_b0290","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1006\/jsre.1996.0302","article-title":"Mechanical characteristics of fresh and frozen human descending thoracic aorta","volume":"64","author":"Adham","year":"1996","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.actbio.2019.08.038_b0295","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1432-2277.2001.tb00053.x","article-title":"Impact of current cryopreservation procedures on mechanical and functional properties of human aortic homografts","volume":"14","author":"Langerak","year":"2001","journal-title":"Transpl. Int."},{"key":"10.1016\/j.actbio.2019.08.038_b0300","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1159\/000159115","article-title":"Effect of age and sex on residual stress in the aorta","volume":"32","author":"Saini","year":"1995","journal-title":"J. Vasc. Res."},{"key":"10.1016\/j.actbio.2019.08.038_b0305","doi-asserted-by":"crossref","first-page":"H1711","DOI":"10.1152\/ajpheart.1996.271.4.H1711","article-title":"Change in intramural strain distribution in rat aorta due to smooth muscle contraction and relaxation","volume":"271","author":"Matsumoto","year":"1996","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.actbio.2019.08.038_b0310","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1115\/1.2798291","article-title":"Experimental investigation of the distribution of residual strains in the artery wall","volume":"119","author":"Greenwald","year":"1997","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.actbio.2019.08.038_b0315","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1007\/s10237-010-0209-7","article-title":"Microstructural and biomechanical alterations of the human aorta as a function of age and location","volume":"9","author":"Haskett","year":"2010","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.actbio.2019.08.038_b0320","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.actbio.2016.06.036","article-title":"Characteristics of thoracic aortic aneurysm rupture in vitro","volume":"42","author":"Luo","year":"2016","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.08.038_b0325","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.actbio.2016.06.028","article-title":"Biaxial rupture properties of ascending thoracic aortic aneurysms","volume":"42","author":"Duprey","year":"2016","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2019.08.038_b0330","first-page":"84","article-title":"Structural modeling reveals microstructure-strength relationship for human ascending thoracic aorta","volume":"71","author":"Thunes","year":"2018","journal-title":"J. Bioeng."},{"key":"10.1016\/j.actbio.2019.08.038_b0335","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jmbbm.2018.09.038","article-title":"Collagen fibre orientation and dispersion govern ultimate tensile strength, stiffness and the fatigue performance of bovine pericardium","volume":"90","author":"Whelan","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174270611930594X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174270611930594X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:21:28Z","timestamp":1761672088000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S174270611930594X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":67,"alternative-id":["S174270611930594X"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2019.08.038","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Failure properties and microstructure of healthy and aneurysmatic human thoracic aortas subjected to uniaxial extension with a focus on the media","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2019.08.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Ltd on behalf of Acta Materialia Inc.","name":"copyright","label":"Copyright"}]}}