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B"},{"key":"10.1016\/j.actbio.2020.03.020_bib0088","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.4161\/21645515.2014.973317","article-title":"Antigen-specific vaccines for cancer treatment","volume":"10","author":"Tagliamonte","year":"2014","journal-title":"Hum. Vaccines Immunother."},{"key":"10.1016\/j.actbio.2020.03.020_bib0089","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1046\/j.1365-2222.2002.01514.x","article-title":"pteronyssinus vaccination in mild asthma patients: effect of 1-year double-blind, placebo-controlled trial on inflammation, bronchial hyperresponsiveness and immediate and late bronchial responses to the allergen","volume":"32","author":"Alvarez","year":"2002","journal-title":"Clin. Exp. Allergy: J. Br. Soc. Allergy Clin. 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Res."},{"key":"10.1016\/j.actbio.2020.03.020_bib0099","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1021\/mp100255c","article-title":"Aerosolized PLA and PLGA nanoparticles enhance humoral, mucosal and cytokine responses to hepatitis B vaccine","volume":"8","author":"Thomas","year":"2011","journal-title":"Mol. Pharmaceut."},{"key":"10.1016\/j.actbio.2020.03.020_bib0100","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0168-3659(02)00275-4","article-title":"Enhancement of immune responses by co-delivery of a CpG oligodeoxynucleotide and tetanus toxoid in biodegradable nanospheres","volume":"85","author":"Diwan","year":"2002","journal-title":"J. Controll. Release: Off. J. Controll. 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Am. Chem. Soc."},{"key":"10.1016\/j.actbio.2020.03.020_bib0116","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.ejps.2011.10.012","article-title":"Synthesis of a novel kind of carbon nanoparticle with large mesopores and macropores and its application as an oral vaccine adjuvant","volume":"44","author":"Wang","year":"2011","journal-title":"Eur. J. Pharmaceut. Sci.: Off. J. Eur. Fed. Pharmaceut. 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J."},{"key":"10.1016\/j.actbio.2020.03.020_bib0119","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143507","article-title":"Silica vesicle nanovaccine formulations stimulate long-term immune responses to the bovine viral diarrhoea virus E2 protein","volume":"10","author":"Mody","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.actbio.2020.03.020_bib0120","doi-asserted-by":"crossref","first-page":"17535","DOI":"10.1021\/acsami.5b05497","article-title":"Lipopeptide-coated iron oxide nanoparticles as potential glycoconjugate-based synthetic anticancer vaccines","volume":"7","author":"Sungsuwan","year":"2015","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2020.03.020_bib0121","doi-asserted-by":"crossref","first-page":"4876","DOI":"10.1021\/acsami.8b20364","article-title":"A visible codelivery nanovaccine of antigen and adjuvant with self-carrier for cancer immunotherapy","volume":"11","author":"Dong","year":"2019","journal-title":"ACS Appl. 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