{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:15:25Z","timestamp":1769818525336,"version":"3.49.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.actbio.2020.11.049","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T20:48:32Z","timestamp":1607114912000},"page":"579-591","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Polymeric micelles coated with hybrid nanovesicles enhance the therapeutic potential of the reversible topoisomerase inhibitor camptothecin in a mouse model"],"prefix":"10.1016","volume":"121","author":[{"given":"Sahil","family":"Malhotra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shweta","family":"Dumoga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akshay","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujata","family":"Mohanty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neetu","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2020.11.049_bib0001","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.2165\/00003495-200262140-00004","article-title":"A review of their chemotherapeutic potential","volume":"62","author":"Ulukan","year":"2002","journal-title":"Drugs"},{"key":"10.1016\/j.actbio.2020.11.049_bib0002","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/j.bmc.2003.11.036","article-title":"Camptothecin: current perspectives","volume":"12","author":"Thomas","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.actbio.2020.11.049_bib0003","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1023\/B:PHAM.0000048190.53439.eb","article-title":"Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting","volume":"21","author":"Opanasopit","year":"2004","journal-title":"Pharm. Res."},{"key":"10.1016\/j.actbio.2020.11.049_bib0004","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s002800050837","article-title":"Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker","volume":"42","author":"Conover","year":"1998","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.actbio.2020.11.049_bib0005","doi-asserted-by":"crossref","first-page":"5352","DOI":"10.1021\/bi00071a010","article-title":"Lipid bilayer partitioning and stability of camptothecin drugs","volume":"32","author":"Burke","year":"1993","journal-title":"Biochemistry"},{"key":"10.1016\/j.actbio.2020.11.049_bib0006","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00001813-199502000-00010","article-title":"Antitumor effect of liposome-incorporated camptothecin in human malignant xenografts","volume":"6","author":"Daoud","year":"1995","journal-title":"Anticancer Drugs"},{"key":"10.1016\/j.actbio.2020.11.049_bib0007","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s002800050425","article-title":"Lipid-complexed camptothecin: formulation and initial biodistribution and antitumor activity studies","volume":"37","author":"Sugarman","year":"1996","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.actbio.2020.11.049_bib0008","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3109\/08982104.2012.742537","article-title":"Liposomal formulations of poorly soluble camptothecin: drug retention and biodistribution","volume":"23","author":"Flaten","year":"2013","journal-title":"J. Liposome Res."},{"key":"10.1016\/j.actbio.2020.11.049_bib0009","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.addr.2011.06.017","article-title":"Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: prediction and prevention","volume":"63","author":"Szebeni","year":"2011","journal-title":"Adv. Drug. Deliv. Rev."},{"key":"10.1016\/j.actbio.2020.11.049_bib0010","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1096\/fj.06-6186fje","article-title":"Methylation of the phosphate oxygen moiety of phospholipid\u2010methoxy (polyethylene glycol) conjugate prevents PEGylated liposome\u2010mediated complement activation and anaphylatoxin production","volume":"20","author":"Moein Moghimi","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.actbio.2020.11.049_bib0011","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1002\/adma.201300638","article-title":"Surface functionalization of gold nanoparticles with red blood cell membranes","volume":"25","author":"Gao","year":"2013","journal-title":"Adv. Mater."},{"key":"10.1016\/j.actbio.2020.11.049_bib0012","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3389\/fphar.2017.00477","article-title":"A red blood cell membrane-camouflaged nanoparticle counteracts streptolysin O-mediated virulence phenotypes of invasive group A Streptococcus","volume":"8","author":"Escajadillo","year":"2017","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.actbio.2020.11.049_bib0013","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1021\/acs.langmuir.5b03014","article-title":"Colloidal properties of nanoerythrosomes derived from bovine red blood cells","volume":"32","author":"Kuo","year":"2016","journal-title":"Langmuir"},{"key":"10.1016\/j.actbio.2020.11.049_bib0014","doi-asserted-by":"crossref","first-page":"10980","DOI":"10.1073\/pnas.1106634108","article-title":"Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform","volume":"108","author":"Hu","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.actbio.2020.11.049_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep02180","article-title":"Erythrocyte-derived photo-theranostic agents: hybrid nano-vesicles containing indocyanine green for near infrared imaging and therapeutic applications","volume":"3","author":"Bahmani","year":"2013","journal-title":"Sci. Rep."},{"key":"10.1016\/j.actbio.2020.11.049_bib0016","doi-asserted-by":"crossref","first-page":"22141","DOI":"10.1021\/acsami.9b04827","article-title":"Red blood cells-derived vesicles for delivery of lipophilic drug camptothecin","volume":"11","author":"Malhotra","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2020.11.049_bib0017","doi-asserted-by":"crossref","first-page":"10414","DOI":"10.1021\/nn503779d","article-title":"Erythrocyte membrane is an alternative coating to polyethylene glycol for prolonging the circulation lifetime of gold nanocages for photothermal therapy","volume":"8","author":"Piao","year":"2014","journal-title":"ACS Nano"},{"key":"10.1016\/j.actbio.2020.11.049_bib0018","doi-asserted-by":"crossref","first-page":"14075","DOI":"10.1002\/anie.201707598","article-title":"Remote loading of small\u2010molecule therapeutics into cholesterol\u2010enriched cell\u2010membrane\u2010derived vesicles","volume":"56","author":"Zhang","year":"2017","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.actbio.2020.11.049_bib0019","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.7150\/thno.14471","article-title":"Safe and immunocompatible nanocarriers cloaked in RBC membranes for drug delivery to treat solid tumors","volume":"6","author":"Luk","year":"2016","journal-title":"Theranostics"},{"key":"10.1016\/j.actbio.2020.11.049_bib0020","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.actbio.2017.06.035","article-title":"Oxygen self-enriched nanoparticles functionalized with erythrocyte membranes for long circulation and enhanced phototherapy","volume":"59","author":"Ren","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2020.11.049_bib0021","doi-asserted-by":"crossref","first-page":"3496","DOI":"10.1021\/acsnano.7b00133","article-title":"Microfluidic electroporation-facilitated synthesis of erythrocyte membrane-coated magnetic nanoparticles for enhanced imaging-guided cancer therapy","volume":"11","author":"Rao","year":"2017","journal-title":"Acs Nano"},{"key":"10.1016\/j.actbio.2020.11.049_bib0022","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1039\/C8BM01448E","article-title":"Biodistribution and toxicological evaluation of micron-and nano-sized erythrocyte-derived optical particles in healthy Swiss Webster mice","volume":"7","author":"Vankayala","year":"2019","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.actbio.2020.11.049_bib0023","doi-asserted-by":"crossref","DOI":"10.1117\/12.2507943","article-title":"Mechanical characterization of erythrocyte-derived optical microparticles by quantitative phase imaging and optical tweezers","author":"Lu","year":"2019","journal-title":"Quantit. Phase Imaging V: Int. Soc. Opt. Photonics"},{"key":"10.1016\/j.actbio.2020.11.049_bib0024","doi-asserted-by":"crossref","first-page":"3900","DOI":"10.1021\/acs.molpharmaceut.0c00641","article-title":"Acute immune response of micro-and nanosized erythrocyte-derived optical particles in healthy mice","volume":"17","author":"Hanley","year":"2020","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.actbio.2020.11.049_bib0025","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1021\/ma980226a","article-title":"Isothermal crystallization of poly (\u03b5-caprolactone\u2212 ethylene glycol) block copolymers","volume":"32","author":"Bogdanov","year":"1999","journal-title":"Macromolecules"},{"key":"10.1016\/j.actbio.2020.11.049_bib0026","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0378-4347(96)00426-4","article-title":"Simple and versatile high-performance liquid chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of camptothecin anticancer drugs","volume":"691","author":"Warner","year":"1997","journal-title":"J. Chromatogr. B: Biomed. Sci. Appl."},{"key":"10.1016\/j.actbio.2020.11.049_bib0027","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/S0032-3861(97)00444-8","article-title":"Synthesis and thermal properties of poly (ethylene glycol)-poly (\u03f5-caprolactone) copolymers","volume":"39","author":"Bogdanov","year":"1998","journal-title":"Polymer"},{"issue":"1","key":"10.1016\/j.actbio.2020.11.049_bib0028","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1182\/blood.V45.1.11.11","article-title":"Role of sialic acid in erythrocyte survival","volume":"45","author":"Durocher","year":"1975","journal-title":"Blood"},{"key":"10.1016\/j.actbio.2020.11.049_bib0029","doi-asserted-by":"crossref","first-page":"10325","DOI":"10.1021\/bi00200a013","article-title":"Differential interactions of camptothecin lactone and carboxylate forms with human blood components","volume":"33","author":"Mi","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.actbio.2020.11.049_bib0030","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1021\/mp800051m","article-title":"Factors affecting the clearance and biodistribution of polymeric nanoparticles","volume":"5","author":"Alexis","year":"2008","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.actbio.2020.11.049_bib0031","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jconrel.2011.09.098","article-title":"The journey of a drug-carrier in the body: an anatomo-physiological perspective","volume":"161","author":"Bertrand","year":"2012","journal-title":"J. Control. Release"},{"key":"10.1016\/j.actbio.2020.11.049_bib0032","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0014-5793(99)00364-6","article-title":"On the mechanism of hepatic transendothelial passage of large liposomes","volume":"448","author":"Romero","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/j.actbio.2020.11.049_bib0033","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0031-6997(24)01494-7","article-title":"Long-circulating and target-specific nanoparticles: theory to practice","volume":"53","author":"Moghimi","year":"2001","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.actbio.2020.11.049_bib0034","first-page":"703","article-title":"Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats","volume":"3","author":"Longmire","year":"2008","journal-title":"Future Med."},{"key":"10.1016\/j.actbio.2020.11.049_bib0035","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1016\/j.jmmm.2003.12.852","article-title":"Long-term retention of dextran-coated magnetite nanoparticles in the liver and spleen","volume":"272","author":"Lacava","year":"2004","journal-title":"J. Magn. Magn. Mater."},{"key":"10.1016\/j.actbio.2020.11.049_bib0036","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.jconrel.2016.01.020","article-title":"Nanoparticle\u2013liver interactions: cellular uptake and hepatobiliary elimination","volume":"240","author":"Zhang","year":"2016","journal-title":"J. Control. Release"},{"key":"10.1016\/j.actbio.2020.11.049_bib0037","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/med.21342","article-title":"Perspectives on biologically active camptothecin derivatives","volume":"35","author":"Liu","year":"2015","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.actbio.2020.11.049_bib0038","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/nsr\/nwx062","article-title":"The acidic tumor microenvironment: a target for smart cancer nano-theranostics","volume":"5","author":"Feng","year":"2018","journal-title":"Natl. Sci. Rev."},{"key":"10.1016\/j.actbio.2020.11.049_bib0039","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1158\/0008-5472.CAN-12-2796","article-title":"Acidity generated by the tumor microenvironment drives local invasion","volume":"73","author":"Estrella","year":"2013","journal-title":"Cancer Res."},{"key":"10.1016\/j.actbio.2020.11.049_bib0040","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/nm1677","article-title":"Tumor-induced anorexia and weight loss are mediated by the TGF-\u03b2 superfamily cytokine MIC-1","volume":"13","author":"Johnen","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.actbio.2020.11.049_bib0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-23669-9","article-title":"Subcutaneous Ehrlich ascites carcinoma mice model for studying cancer-induced cardiomyopathy","volume":"8","author":"Mishra","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.actbio.2020.11.049_bib0042","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1159\/000444941","article-title":"Until death do us part: necrosis and oxidation promote the tumor microenvironment","volume":"43","author":"Lotfi","year":"2016","journal-title":"Transfusion Med. Hemotherapy"},{"key":"10.1016\/j.actbio.2020.11.049_bib0043","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/3537471","article-title":"Regulation of tumor progression by programmed necrosis","author":"Lee","year":"2018","journal-title":"Oxidat. Med. Cellular Longevity"},{"key":"10.1016\/j.actbio.2020.11.049_bib0044","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.cell.2008.01.046","article-title":"TGF\u03b2 primes breast tumors for lung metastasis seeding through angiopoietin-like 4","volume":"133","author":"Padua","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.actbio.2020.11.049_bib0045","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1080\/15384047.2018.1456599","article-title":"Breast cancer lung metastasis: molecular biology and therapeutic implications","volume":"19","author":"Jin","year":"2018","journal-title":"Cancer Biol. Ther."},{"key":"10.1016\/j.actbio.2020.11.049_bib0046","doi-asserted-by":"crossref","first-page":"28001","DOI":"10.1039\/C7RA02069D","article-title":"Metabonomic analysis of metastatic lung tissue in breast cancer mice by an integrated NMR-based metabonomics approach","volume":"7","author":"Yang","year":"2017","journal-title":"RSC Adv."},{"key":"10.1016\/j.actbio.2020.11.049_bib0047","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1002\/hep.20174","article-title":"Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF\u2010mediated apoptosis","volume":"39","author":"Hentze","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.actbio.2020.11.049_bib0048","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1179\/joc.2000.12.4.345","article-title":"Hepatotoxicity of camptothecin derivatives in a primary culture system of rat hepatocytes","volume":"12","author":"Fulco","year":"2000","journal-title":"J. Chemother."},{"key":"10.1016\/j.actbio.2020.11.049_bib0049","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1038\/sj.bjp.0704363","article-title":"Effect of P\u2010glycoprotein modulators on the pharmacokinetics of camptothecin using microdialysis","volume":"134","author":"Tsai","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.actbio.2020.11.049_bib0050","first-page":"641","article-title":"Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins","volume":"8","author":"Garcia-Carbonero","year":"2002","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.actbio.2020.11.049_bib0051","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.tiv.2005.09.016","article-title":"Human primary renal cells as a model for toxicity assessment of chemo-therapeutic drugs","volume":"20","author":"Li","year":"2006","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.actbio.2020.11.049_bib0052","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1056\/NEJMra0809139","article-title":"Renal failure in cirrhosis","volume":"361","author":"Gin\u00e8s","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.actbio.2020.11.049_bib0053","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.jhep.2011.10.016","article-title":"Renal failure and cirrhosis: a systematic review of mortality and prognosis","volume":"56","author":"Fede","year":"2012","journal-title":"J. Hepatol."},{"key":"10.1016\/j.actbio.2020.11.049_bib0054","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0002-9343(70)80073-0","article-title":"Renal failure in the patient with cirrhosis: the role of active vasoconstriction","volume":"49","author":"Epstein","year":"1970","journal-title":"Am. J. Med."},{"key":"10.1016\/j.actbio.2020.11.049_bib0055","doi-asserted-by":"crossref","first-page":"H466","DOI":"10.1152\/ajpheart.00720.2015","article-title":"The pathogenesis and treatment of cardiac atrophy in cancer cachexia","volume":"310","author":"Murphy","year":"2016","journal-title":"Am. J. Physiol.-Heart Circulat. Physiol."},{"key":"10.1016\/j.actbio.2020.11.049_bib0056","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/eurheartj\/eht302","article-title":"Prevention of liver cancer cachexia-induced cardiac wasting and heart failure","volume":"35","author":"Springer","year":"2014","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.actbio.2020.11.049_bib0057","doi-asserted-by":"crossref","first-page":"165","DOI":"10.5625\/lar.2017.33.2.165","article-title":"Comparision of doxorubicin-induced cardiotoxicity in the ICR mice of different sources","volume":"33","author":"Kim","year":"2017","journal-title":"Lab. Anim. Res."},{"key":"10.1016\/j.actbio.2020.11.049_bib0058","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1186\/s12906-017-2061-0","article-title":"Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats","volume":"17","author":"Afsar","year":"2017","journal-title":"BMC Complement. Alternat. Med."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706120307030?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706120307030?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:37:19Z","timestamp":1761673039000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706120307030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":58,"alternative-id":["S1742706120307030"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2020.11.049","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Polymeric micelles coated with hybrid nanovesicles enhance the therapeutic potential of the reversible topoisomerase inhibitor camptothecin in a mouse model","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2020.11.049","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}