{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:58:01Z","timestamp":1789588681167,"version":"build-2803163510"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21874096"],"award-info":[{"award-number":["21874096"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012462","name":"Collaborative Innovation Center of Suzhou Nano Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012462","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005075","name":"Universitair Medisch Centrum Groningen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005075","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2017YFE0131700"],"award-info":[{"award-number":["2017YFE0131700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.actbio.2021.01.032","type":"journal-article","created":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T09:58:13Z","timestamp":1611741493000},"page":"230-243","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["PAMAM dendrimers with dual-conjugated vancomycin and Ag-nanoparticles do not induce bacterial resistance and kill vancomycin-resistant Staphylococci"],"prefix":"10.1016","volume":"123","author":[{"given":"Guimei","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianrong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renfei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijin","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henny C.","family":"van der Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henk J.","family":"Busscher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2021.01.032_bib0001","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/nrd.2016.155","article-title":"Accelerating global innovation to address antibacterial resistance: introducing CARB-X","volume":"15","author":"Outterson","year":"2016","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.actbio.2021.01.032_bib0002","doi-asserted-by":"crossref","first-page":"638","DOI":"10.2471\/BLT.16.020916","article-title":"United nations meeting on antimicrobial resistance","volume":"94","author":"Humphreys","year":"2016","journal-title":"Bull. World Health Organ"},{"key":"10.1016\/j.actbio.2021.01.032_bib0003","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1586\/eri.11.90","article-title":"Bacteriophage therapy: potential uses in the control of antibiotic-resistant pathogens","volume":"9","author":"Burrowes","year":"2011","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"10.1016\/j.actbio.2021.01.032_bib0004","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/cc13948","article-title":"The future of antibiotics","volume":"18","author":"Spellberg","year":"2014","journal-title":"Crit. Care"},{"key":"10.1016\/j.actbio.2021.01.032_bib0005","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1039\/C7CS00807D","article-title":"Nanotechnology-based antimicrobials and delivery systems for biofilm-infection control","volume":"48","author":"Liu","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.actbio.2021.01.032_bib0006","doi-asserted-by":"crossref","first-page":"5737","DOI":"10.1021\/acsnano.7b01240","article-title":"Pharmaceutical intermediate-modified gold nanoparticles: against multidrug-resistant bacteria and wound-healing application via an electrospun scaffold","volume":"11","author":"Yang","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.actbio.2021.01.032_bib0007","doi-asserted-by":"crossref","first-page":"6904","DOI":"10.1021\/acsnano.7b02035","article-title":"Antimicrobial gold nanoclusters","volume":"11","author":"Zheng","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.actbio.2021.01.032_bib0008","doi-asserted-by":"crossref","first-page":"8461","DOI":"10.1021\/acsami.8b22143","article-title":"Exploring the antibacteria performance of multicolor Ag, Au, and Cu nanoclusters","volume":"11","author":"Wang","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2021.01.032_bib0009","doi-asserted-by":"crossref","first-page":"4271","DOI":"10.1021\/nl301934w","article-title":"Negligible particle-specific antibacterial activity of silver nanoparticles","volume":"12","author":"Xiu","year":"2012","journal-title":"Nano Lett"},{"key":"10.1016\/j.actbio.2021.01.032_bib0010","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1039\/C3CS60218D","article-title":"Nanosilver-based antibacterial drugs and devices: mechanisms, methodological drawbacks, and guidelines","volume":"43","author":"Rizzello","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.actbio.2021.01.032_bib0011","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.biomaterials.2016.06.004","article-title":"Antibiotic-loaded, silver core-embedded mesoporous silica nanovehicles as a synergistic antibacterial agent for the treatment of drug-resistant infections","volume":"101","author":"Wang","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2021.01.032_bib0012","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1007\/s11051-008-9428-6","article-title":"Synthesis and antibacterial activity of silver nanoparticles with different sizes","volume":"10","author":"Martinez-Castanon","year":"2008","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.actbio.2021.01.032_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2020.110735","article-title":"Size-controllable preparation and antibacterial mechanism of thermo-responsive copolymer-stabilized silver nanoparticles with high antimicrobial activity","volume":"110","author":"Ji","year":"2020","journal-title":"Mater. Sci. Eng. C."},{"key":"10.1016\/j.actbio.2021.01.032_bib0014","first-page":"16881","article-title":"Silver-decorated polymeric micelles combined with curcumin for enhanced antibacterial activity","volume":"9","author":"Huang","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2021.01.032_bib0015","doi-asserted-by":"crossref","first-page":"3448","DOI":"10.1039\/c3py00393k","article-title":"Ultrafine silver nanoparticles with excellent antibacterial efficacy prepared by a handover of vesicle templating to micelle stabilization","volume":"4","author":"Lu","year":"2013","journal-title":"Polym. Chem."},{"key":"10.1016\/j.actbio.2021.01.032_bib0016","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.1021\/acs.jcim.0c00052","article-title":"Effect of the generation of pamam dendrimers on the stabilization of gold nanoparticles","volume":"60","author":"Avila-Salas","year":"2020","journal-title":"J. Chem. Inf. Model."},{"key":"10.1016\/j.actbio.2021.01.032_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2020.213463","article-title":"Superstructured poly(amidoamine) dendrimer-based nanoconstructs as platforms for cancer nanomedicine: a concise review","volume":"421","author":"Song","year":"2020","journal-title":"Coordin. Chem. Rev."},{"key":"10.1016\/j.actbio.2021.01.032_bib0018","doi-asserted-by":"crossref","first-page":"15212","DOI":"10.1021\/acsami.8b21679","article-title":"Zwitterionic gadolinium(III)-complexed dendrimer-entrapped gold nanoparticles for enhanced computed tomography\/magnetic resonance imaging of lung cancer metastasis","volume":"11","author":"Liu","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2021.01.032_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2020.112238","article-title":"An electrochemical immunosensor using gold nanoparticles-PAMAM-nanostructured screen-printed carbon electrodes for tau protein determination in plasma and brain tissues from Alzheimer patients","volume":"163","author":"Razzino","year":"2020","journal-title":"Biosensors Bioelec."},{"key":"10.1016\/j.actbio.2021.01.032_bib0020","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/nchembio.559","article-title":"Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy","volume":"7","author":"Ejim","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.actbio.2021.01.032_bib0021","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.cmi.2019.10.029","article-title":"Vancomycin area under the curve to minimum inhibitory concentration ratio predicting clinical outcome: a systematic review and meta-analysis with pooled sensitivity and specificity","volume":"26","author":"Dalton","year":"2020","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.actbio.2021.01.032_bib0022","first-page":"107","article-title":"Topical versus systemic vancomycin for deep sternal wound infection caused by methicillin-resistant Staphylococcus aureus in a rodent experimental model","volume":"33","author":"Ozcan","year":"2006","journal-title":"Tex. Heart Inst. J."},{"key":"10.1016\/j.actbio.2021.01.032_bib0023","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1021\/nn3038995","article-title":"Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface","volume":"7","author":"Choi","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.actbio.2021.01.032_bib0024","doi-asserted-by":"crossref","first-page":"36814","DOI":"10.1021\/acsami.8b16092","article-title":"Antibacterial micelles with vancomycin-mediated targeting and pH\/lipase-triggered release of antibiotics","volume":"10","author":"Chen","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2021.01.032_bib0025","doi-asserted-by":"crossref","first-page":"6417","DOI":"10.1007\/s12274-018-2166-x","article-title":"Highly fluorescent, photostable, and biocompatible silicon theranostic nanoprobes against Staphylococcus aureus infections","volume":"11","author":"Zhai","year":"2018","journal-title":"Nano Res."},{"key":"10.1016\/j.actbio.2021.01.032_bib0026","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1021\/nl051077u","article-title":"Silver\/dendrimer nanocomposites as biomarkers: fabrication, characterization, in vitro toxicity, and intracellular detection","volume":"5","author":"Lesniak","year":"2005","journal-title":"Nano Lett."},{"key":"10.1016\/j.actbio.2021.01.032_bib0027","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201701974","article-title":"Eradication of multidrug resistant staphylococcal infections by light activatable micellar nanocarriers in a murine model","volume":"27","author":"Liu","year":"2017","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.actbio.2021.01.032_bib0028","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0167-7012(99)00048-2","article-title":"Live\/dead baclight: application of a new rapid staining method for direct enumeration of viable and total bacteria in drinking water","volume":"37","author":"Boulos","year":"1999","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.actbio.2021.01.032_bib0029","doi-asserted-by":"crossref","first-page":"3094","DOI":"10.1021\/acs.bioconjchem.8b00452","article-title":"Mercaptopyrimidine-conjugated gold nanoclusters as nanoantibiotics for combating multidrug-resistant superbugs","volume":"29","author":"Zheng","year":"2018","journal-title":"Bioconjugate Chem."},{"key":"10.1016\/j.actbio.2021.01.032_bib0030","doi-asserted-by":"crossref","first-page":"15163","DOI":"10.1021\/acsami.8b02527","article-title":"A nanocomposite hydrogel with potent and broad-spectrum antibacterial activity","volume":"10","author":"Dai","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2021.01.032_bib0031","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/BOT.0000000000000617","article-title":"Time-dependent effectiveness of locally applied vancomycin powder in a contaminated traumatic orthopaedic wound model","volume":"30","author":"Tennent","year":"2016","journal-title":"J. Orthop. Trauma"},{"key":"10.1016\/j.actbio.2021.01.032_bib0032","doi-asserted-by":"crossref","first-page":"031","DOI":"10.1515\/epoly.2009.9.1.375","article-title":"The thermal behaviors of Ag\/polyamidoamine nanocomposites","volume":"9","author":"Peng","year":"2009","journal-title":"e-Polymers"},{"key":"10.1016\/j.actbio.2021.01.032_bib0033","doi-asserted-by":"crossref","first-page":"3553","DOI":"10.1039\/c0cc05058j","article-title":"Functionalizd Ag nanoparticles with tunable optical properties for selective protein analysis","volume":"47","author":"Sivanesan","year":"2011","journal-title":"Chem. Commun."},{"key":"10.1016\/j.actbio.2021.01.032_bib0034","doi-asserted-by":"crossref","first-page":"812","DOI":"10.3390\/polym3020812","article-title":"Counterion condensation and effective charge of PAMAM dendrimers","volume":"3","author":"B\u00f6hme","year":"2011","journal-title":"Polymers (Basel)"},{"key":"10.1016\/j.actbio.2021.01.032_bib0035","doi-asserted-by":"crossref","first-page":"10357","DOI":"10.1039\/C6CC05179K","article-title":"Light-controlled active release of photocaged ciprofloxacin for lipopolysaccharide-targeted drug delivery using dendrimer conjugates","volume":"52","author":"Wong","year":"2016","journal-title":"Chem. Commun."},{"key":"10.1016\/j.actbio.2021.01.032_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2019.119737","article-title":"Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies","volume":"232","author":"Busscher","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2021.01.032_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.mimet.2020.105881","article-title":"Microplate immunocapture coupled with the 3\u00a0M molecular detection system and selective plating for the rapid detection of Salmonella infantis in dry dog food and treats","volume":"172","author":"Rosen","year":"2020","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.actbio.2021.01.032_bib0038","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.ijantimicag.2015.09.007","article-title":"Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus","volume":"46","author":"Daghighi","year":"2015","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.actbio.2021.01.032_bib0039","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/1091581819859267","article-title":"An alternative in vitro method for examining nanoparticle-induced cytotoxicity","volume":"38","author":"Gu","year":"2019","journal-title":"Int. J. Toxicol."},{"key":"10.1016\/j.actbio.2021.01.032_bib0040","doi-asserted-by":"crossref","first-page":"S919","DOI":"10.4103\/2152-7806.195227","article-title":"Safety of topical vancomycin powder in neurosurgery","volume":"7","author":"Abdullah","year":"2016","journal-title":"Surg. Neurol. Int."},{"key":"10.1016\/j.actbio.2021.01.032_bib0041","article-title":"Silver nanoparticles and silver ions cause inflammatory response through induction of cell necrosis and the release of mitochondria in vivo and in vitro","author":"Li","year":"2020","journal-title":"Cell Biol. Toxicol."},{"key":"10.1016\/j.actbio.2021.01.032_bib0042","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.colsurfb.2018.12.043","article-title":"Synergetic effect of vancomycin loaded silver nanoparticles for enhanced antibacterial activity","volume":"176","author":"Kaur","year":"2019","journal-title":"Colloids Surfaces B"},{"key":"10.1016\/j.actbio.2021.01.032_bib0043","doi-asserted-by":"crossref","first-page":"479","DOI":"10.15171\/apb.2017.058","article-title":"Vancomycin capped with silver nanoparticles as an antibacterial agent against multi-drug resistance bacteria","volume":"7","author":"Esmaeillou","year":"2017","journal-title":"Adv. Pharm. Bull."},{"key":"10.1016\/j.actbio.2021.01.032_bib0044","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1002\/cyto.a.20402","article-title":"Limits of propidium iodide as a cell viability indicator for environmental bacteria","volume":"71A","author":"Shi","year":"2007","journal-title":"Cytometry A"},{"key":"10.1016\/j.actbio.2021.01.032_bib0045","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1038\/s41467-019-09356-x","article-title":"Coordination of capsule assembly and cell wall biosynthesis in Staphylococcus aureus","volume":"10","author":"Rausch","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.actbio.2021.01.032_bib0046","first-page":"667","article-title":"Development and validation of a multi-dose neutropenic rat thigh infection model using real-time monitoring of Staphylococcus aureus growth in vivo","volume":"22","author":"Zhang","year":"2008","journal-title":"In Vivo (Brooklyn)"},{"key":"10.1016\/j.actbio.2021.01.032_bib0047","series-title":"Current Diagnosis and Treatment: Nephrology and Hypertension","first-page":"14","article-title":"Acute renal failure from therapeutic agents","author":"Olyaei","year":"2009"},{"key":"10.1016\/j.actbio.2021.01.032_bib0048","doi-asserted-by":"crossref","first-page":"6955","DOI":"10.1021\/acsami.9b22043","article-title":"Facile assembly of multifunctional antibacterial nanoplatform leveraging synergistic sensitization between silver nanostructure and vancomycin","volume":"12","author":"Ma","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.actbio.2021.01.032_bib0049","doi-asserted-by":"crossref","first-page":"3958","DOI":"10.1002\/anie.201712878","article-title":"Gold nanoclusters for targeting methicillin-resistant Staphylococcus\u2005aureus in\u2005vivo","volume":"57","author":"Xie","year":"2018","journal-title":"Angew. Chem. Int. Edit."},{"key":"10.1016\/j.actbio.2021.01.032_bib0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1021\/acs.bioconjchem.9b00739","article-title":"Silver nanoparticle conjugated star PCL-b-AMPs copolymer as nanocomposite exhibits efficient antibacterial properties","volume":"31","author":"Zhen","year":"2020","journal-title":"Bioconjugate Chem."},{"key":"10.1016\/j.actbio.2021.01.032_bib0051","doi-asserted-by":"crossref","first-page":"10682","DOI":"10.1021\/nn5042625","article-title":"Functional gold nanoparticles as potent antimicrobial agents against multi-drug-resistant bacteria","volume":"8","author":"Li","year":"2014","journal-title":"ACS Nano"},{"key":"10.1016\/j.actbio.2021.01.032_bib0052","doi-asserted-by":"crossref","first-page":"6176","DOI":"10.1021\/jacs.8b03575","article-title":"Biodegradable nanocomposite antimicrobials for the eradication of multidrug-resistant bacterial biofilms without accumulated resistance","volume":"140","author":"Landis","year":"2018","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.actbio.2021.01.032_bib0053","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/femsre\/fux010","article-title":"Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria","volume":"41","author":"Hall","year":"2017","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.actbio.2021.01.032_bib0054","doi-asserted-by":"crossref","first-page":"8268","DOI":"10.1021\/acs.jmedchem.7b00215","article-title":"Pharmaceutical approaches to target antibiotic resistance mechanisms","volume":"60","author":"Schillaci","year":"2017","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.actbio.2021.01.032_bib0055","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1128\/CMR.00042-09","article-title":"Reduced vancomycin susceptibility in Staphylococcus aureus, including vancomycin-intermediate and heterogeneous vancomycin-intermediate strains: resistance mechanisms, laboratory detection, and clinical implications","volume":"23","author":"Howden","year":"2010","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.actbio.2021.01.032_bib0056","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ijid.2014.12.038","article-title":"Vancomycin intermediate-resistant Staphylococcus aureus (VISA) isolated from a patient who never received vancomycin treatment","volume":"33","author":"Zhu","year":"2015","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.actbio.2021.01.032_bib0057","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1111\/j.1365-2672.2012.05253.x","article-title":"Silver nanoparticles: the powerful nanoweapon against multidrug-resistant bacteria","volume":"112","author":"Rai","year":"2012","journal-title":"J. Appl. Microbiol."}],"updated-by":[{"DOI":"10.1016\/j.actbio.2024.06.044","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000}}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174270612100060X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S174270612100060X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:37:33Z","timestamp":1761673053000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S174270612100060X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":57,"alternative-id":["S174270612100060X"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2021.01.032","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PAMAM dendrimers with dual-conjugated vancomycin and Ag-nanoparticles do not induce bacterial resistance and kill vancomycin-resistant Staphylococci","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2021.01.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd on behalf of Acta Materialia Inc.","name":"copyright","label":"Copyright"}]}}