{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:49:17Z","timestamp":1792795757521,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51873085"],"award-info":[{"award-number":["51873085"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018617","name":"Liaoning Revitalization Talents Program","doi-asserted-by":"publisher","award":["XLYC2007056"],"award-info":[{"award-number":["XLYC2007056"]}],"id":[{"id":"10.13039\/501100018617","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.actbio.2021.09.051","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T03:52:19Z","timestamp":1633060339000},"page":"485-494","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Endogenous NO-releasing Carbon Nanodots for Tumor-specific Gas Therapy"],"prefix":"10.1016","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5187-0354","authenticated-orcid":false,"given":"Xue","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avnesh S.","family":"Thakor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavesh D.","family":"Kevadiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiamin","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuhua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guolin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2021.09.051_bib0001","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.canlet.2015.07.008","article-title":"Reactive oxygen species in redox cancer therapy","volume":"367","author":"Tong","year":"2015","journal-title":"Cancer Lett"},{"key":"10.1016\/j.actbio.2021.09.051_bib0002","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1002\/smll.201400437","article-title":"Preparation of a mitochondria-targeted and NO-releasing nanoplatform and its enhanced pro-apoptotic effect on cancer cells","volume":"10","author":"Xu","year":"2014","journal-title":"Small"},{"key":"10.1016\/j.actbio.2021.09.051_bib0003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.niox.2017.10.009","article-title":"Distinct role of endothelial nitric oxide synthase gene polymorphisms from menopausal status in the patients with sporadic breast cancer in Taiwan","volume":"72","author":"Chen","year":"2018","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.actbio.2021.09.051_bib0004","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.3390\/molecules19033654","article-title":"Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells","volume":"19","author":"Xia","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.actbio.2021.09.051_bib0005","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1093\/cvr\/cvw037","article-title":"Additive cardioprotection by pharmacological postconditioning with hydrogen sulfide and nitric oxide donors in mouse heart: S-sulfhydration vs. S-nitrosylation","volume":"110","author":"Sun","year":"2016","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.actbio.2021.09.051_bib0006","doi-asserted-by":"crossref","first-page":"13404","DOI":"10.1039\/C7NR04832G","article-title":"Multivalent mesoporous silica nanoparticles photo-delivering nitric oxide with carbon dots as fluorescence reporters","volume":"9","author":"Afonso","year":"2017","journal-title":"Nanoscale"},{"key":"10.1016\/j.actbio.2021.09.051_bib0007","doi-asserted-by":"crossref","first-page":"4179","DOI":"10.1039\/C7NR08176F","article-title":"NO prodrug-conjugated, self-assembled, pH-responsive and galactose receptor targeted nanoparticles for co-delivery of nitric oxide and doxorubicin","volume":"10","author":"Zhang","year":"2018","journal-title":"Nanoscale"},{"key":"10.1016\/j.actbio.2021.09.051_bib0008","doi-asserted-by":"crossref","first-page":"3742","DOI":"10.1039\/c2cs15273h","article-title":"Nitric oxide release: part II. Therapeutic applications","volume":"41","author":"Carpenter","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.actbio.2021.09.051_bib0009","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jconrel.2015.09.019","article-title":"A novel nitric oxide-based anticancer therapeutics by macrophage-targeted poly(l-arginine)-based nanoparticles","volume":"217","author":"Kudo","year":"2015","journal-title":"J. Control. Release"},{"key":"10.1016\/j.actbio.2021.09.051_bib0010","doi-asserted-by":"crossref","first-page":"11038","DOI":"10.1074\/jbc.273.18.11038","article-title":"Production of nitric oxide by mitochondria","volume":"273","author":"Giulivi","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.actbio.2021.09.051_bib0011","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.trecan.2017.07.005","article-title":"Nitric Oxide: The Forgotten Child of Tumor Metabolism","volume":"3","author":"Rizi","year":"2017","journal-title":"Trends Cancer"},{"key":"10.1016\/j.actbio.2021.09.051_bib0012","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/smll.201200458","article-title":"Nitric oxide donors for cardiovascular implant applications","volume":"9","author":"Naghavi","year":"2013","journal-title":"Small"},{"key":"10.1016\/j.actbio.2021.09.051_bib0013","doi-asserted-by":"crossref","first-page":"8383","DOI":"10.1002\/anie.201800594","article-title":"Stimuli-Responsive NO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy","volume":"57","author":"Fan","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.actbio.2021.09.051_bib0014","doi-asserted-by":"crossref","first-page":"10887","DOI":"10.1021\/acsnano.9b04954","article-title":"Gas-Mediated Cancer Bioimaging and Therapy","volume":"13","author":"Chen","year":"2019","journal-title":"ACS Nano"},{"key":"10.1016\/j.actbio.2021.09.051_bib0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2012.09.023","article-title":"Real-time visualization of pH-responsive PLGA hollow particles containing a gas-generating agent targeted for acidic organelles for overcoming multi-drug resistance","volume":"34","author":"Ke","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2021.09.051_bib0016","doi-asserted-by":"crossref","first-page":"9890","DOI":"10.1002\/anie.201504444","article-title":"A pH-Responsive Carrier System that Generates NO Bubbles to Trigger Drug Release and Reverse P-Glycoprotein-Mediated Multidrug Resistance","volume":"54","author":"Chung","year":"2015","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.actbio.2021.09.051_bib0017","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1039\/B912493B","article-title":"Nitric oxide-releasing vehicles for biomedical applications","volume":"20","author":"Seabra","year":"2010","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.actbio.2021.09.051_bib0018","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jconrel.2015.05.283","article-title":"Enzyme-functionalized vascular grafts catalyze in-situ release of nitric oxide from exogenous NO prodrug","volume":"210","author":"Wang","year":"2015","journal-title":"J. Control. Release"},{"key":"10.1016\/j.actbio.2021.09.051_bib0019","first-page":"380","article-title":"The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment","volume":"14","author":"Qin","year":"2019","journal-title":"Asian J. Pharm."},{"key":"10.1016\/j.actbio.2021.09.051_bib0020","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1021\/cr000040l","article-title":"Nitric oxide donors: chemical activities and biological applications","volume":"102","author":"Wang","year":"2002","journal-title":"Chem. Rev."},{"key":"10.1016\/j.actbio.2021.09.051_bib0021","doi-asserted-by":"crossref","first-page":"14602","DOI":"10.1021\/jacs.5b10420","article-title":"Chemical Mutagenesis of an Emissive RNA Alphabet","volume":"137","author":"Rovira","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.actbio.2021.09.051_bib0022","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1006\/bbrc.1997.6428","article-title":"A novel nonenzymatic pathway for the generation of nitric oxide by the reaction of hydrogen peroxide and D- or L-arginine","volume":"233","author":"Nagase","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.actbio.2021.09.051_bib0023","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/nrc1478","article-title":"Why do cancers have high aerobic glycolysis?","volume":"4","author":"Gatenby","year":"2004","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.actbio.2021.09.051_bib0024","doi-asserted-by":"crossref","first-page":"4118","DOI":"10.1021\/mp5003009","article-title":"Nitric oxide releasing d-alpha-tocopheryl polyethylene glycol succinate for enhancing antitumor activity of doxorubicin","volume":"11","author":"Song","year":"2014","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.actbio.2021.09.051_bib0025","first-page":"47","article-title":"[Photodynamic therapy (PDT) for early cervical cancer]","volume":"23","author":"Muroya","year":"1996","journal-title":"Gan To Kagaku Ryoho"},{"key":"10.1016\/j.actbio.2021.09.051_bib0026","doi-asserted-by":"crossref","first-page":"99","DOI":"10.2165\/11596860-000000000-00000","article-title":"The effect of nitric-oxide-related supplements on human performance","volume":"42","author":"Bescos","year":"2012","journal-title":"Sports Med"},{"key":"10.1016\/j.actbio.2021.09.051_bib0027","doi-asserted-by":"crossref","first-page":"19278","DOI":"10.1021\/ja2073824","article-title":"Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs","volume":"133","author":"Kuang","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.actbio.2021.09.051_bib0028","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1002\/smll.201000173","article-title":"Bubble microreactors triggered by an alternating magnetic field as diagnostic and therapeutic delivery devices","volume":"6","author":"Yang","year":"2010","journal-title":"Small"},{"key":"10.1016\/j.actbio.2021.09.051_bib0029","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1002\/anie.201610682","article-title":"Glucose-Responsive Sequential Generation of Hydrogen Peroxide and Nitric Oxide for Synergistic Cancer Starving-Like\/Gas Therapy","volume":"56","author":"Fan","year":"2017","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.actbio.2021.09.051_bib0030","doi-asserted-by":"crossref","first-page":"5187","DOI":"10.1039\/C7TA00397H","article-title":"Direct synthesis of carbon quantum dots in aqueous polymer solution: one-pot reaction and preparation of transparent UV-blocking films","volume":"5","author":"Hess","year":"2017","journal-title":"J. Mater. Chem. A"},{"key":"10.1016\/j.actbio.2021.09.051_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2020.116135","article-title":"Carbon dots in sample preparation and chromatographic separation: Recent advances and future prospects","volume":"134","author":"Chen","year":"2021","journal-title":"Trends Analyt. Chem."},{"key":"10.1016\/j.actbio.2021.09.051_bib0032","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1002\/pssb.201552226","article-title":"Prediction and theoretical investigation of new 2D and 3D periodical structures, having graphene-like bandstructures","volume":"252","author":"Fedorov","year":"2015","journal-title":"Phys. Status Solidi B"},{"key":"10.1016\/j.actbio.2021.09.051_bib0033","doi-asserted-by":"crossref","first-page":"14251","DOI":"10.1103\/PhysRevB.49.14251","article-title":"Ab initio molecular-dynamics simulation of the liquid-metal-amorphous-semiconductor transition in germanium","volume":"49","author":"Kresse","year":"1994","journal-title":"Phys. Rev. B"},{"key":"10.1016\/j.actbio.2021.09.051_bib0034","doi-asserted-by":"crossref","first-page":"11169","DOI":"10.1103\/PhysRevB.54.11169","article-title":"Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set","volume":"54","author":"Kresse","year":"1996","journal-title":"Phys. Rev. B"},{"key":"10.1016\/j.actbio.2021.09.051_bib0035","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1002\/jcc.20495","article-title":"Semiempirical GGA-type density functional constructed with a long-range dispersion correction","volume":"27","author":"Grimme","year":"2006","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.actbio.2021.09.051_bib0036","doi-asserted-by":"crossref","first-page":"13115","DOI":"10.1103\/PhysRevB.48.13115","article-title":"Ab initio molecular dynamics for open-shell transition metals","volume":"48","author":"Kresse","year":"1993","journal-title":"Phys. Rev. B"},{"key":"10.1016\/j.actbio.2021.09.051_bib0037","series-title":"Fundamentals of Time-Dependent Density Functional Theory","first-page":"391","article-title":"The Projector Augmented Wave Method","author":"Lehtovaara","year":"2012"},{"key":"10.1016\/j.actbio.2021.09.051_bib0038","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1103\/PhysRevLett.77.3865","article-title":"Generalized Gradient Approximation Made Simple","volume":"77","author":"Perdew","year":"1996","journal-title":"Phys. Rev. Lett."},{"key":"10.1016\/j.actbio.2021.09.051_bib0039","doi-asserted-by":"crossref","first-page":"5188","DOI":"10.1103\/PhysRevB.13.5188","article-title":"Special points for Brillouin-zone integrations","volume":"13","author":"Monkhorst","year":"1976","journal-title":"Phys. Rev. B"},{"key":"10.1016\/j.actbio.2021.09.051_bib0040","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.biomaterials.2018.09.004","article-title":"ROS-induced NO generation for gas therapy and sensitizing photodynamic therapy of tumor","volume":"185","author":"Wan","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2021.09.051_bib0041","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.mattod.2015.11.008","article-title":"Carbon dots: large-scale synthesis, sensing and bioimaging","volume":"19","author":"Zhang","year":"2016","journal-title":"Mater. Today"},{"key":"10.1016\/j.actbio.2021.09.051_bib0042","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.ab.2004.03.044","article-title":"Chemiluminescence from the Sakaguchi reaction","volume":"329","author":"Francis","year":"2004","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.actbio.2021.09.051_bib0043","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1002\/(SICI)1521-3773(19991102)38:21<3209::AID-ANIE3209>3.0.CO;2-6","article-title":"Fluorescent Indicators for Imaging Nitric Oxide Production","volume":"38","author":"Kojima","year":"1999","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.actbio.2021.09.051_bib0044","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1006\/niox.2000.0319","article-title":"A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite","volume":"5","author":"Miranda","year":"2001","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.actbio.2021.09.051_bib0045","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1002\/adma.201405141","article-title":"Intelligent MnO2 Nanosheets Anchored with Upconversion Nanoprobes for Concurrent pH-\/H2O2-Responsive UCL Imaging and Oxygen-Elevated Synergetic Therapy","volume":"27","author":"Fan","year":"2015","journal-title":"Adv. Mater."},{"key":"10.1016\/j.actbio.2021.09.051_bib0046","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1039\/C7CC00670E","article-title":"Ruthenium nitrosyl functionalized graphene quantum dots as an efficient nanoplatform for NIR-light-controlled and mitochondria-targeted delivery of nitric oxide combined with photothermal therapy","volume":"53","author":"Guo","year":"2017","journal-title":"Chem. Commun."},{"key":"10.1016\/j.actbio.2021.09.051_bib0047","first-page":"44","article-title":"The Interaction between Glycine and Carbon Nanostructure","volume":"1","author":"Naderi","year":"2010","journal-title":"Org. Chem. J."},{"key":"10.1016\/j.actbio.2021.09.051_bib0048","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.theochem.2010.06.007","article-title":"Adsorption of cysteine molecule on intrinsic and Pt-doped graphene: A first-principle study","volume":"955","author":"Ma","year":"2010","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.actbio.2021.09.051_bib0049","doi-asserted-by":"crossref","first-page":"5708","DOI":"10.1021\/jp310088e","article-title":"Density Functional Theory Study of the Interaction of Arginine-Glycine-Aspartic Acid with Graphene, Defective Graphene, and Graphene Oxide","volume":"117","author":"Guo","year":"2013","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.actbio.2021.09.051_bib0050","doi-asserted-by":"crossref","first-page":"4411","DOI":"10.1021\/la703696f","article-title":"TiO2 band shift by nitrogen-containing heterocycles in dye-sensitized solar cells: a periodic density functional theory study","volume":"24","author":"Kusama","year":"2008","journal-title":"Langmuir"},{"key":"10.1016\/j.actbio.2021.09.051_bib0051","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.carbon.2016.03.040","article-title":"Long lifetime photoluminescence in N, S co-doped carbon quantum dots from an ionic liquid and their applications in ultrasensitive detection of pesticides","volume":"104","author":"Li","year":"2016","journal-title":"Carbon"},{"key":"10.1016\/j.actbio.2021.09.051_bib0052","first-page":"794","article-title":"Production of large amounts of hydrogen peroxide by human tumor cells","volume":"51","author":"Szatrowski","year":"1991","journal-title":"Cancer Res"},{"key":"10.1016\/j.actbio.2021.09.051_bib0053","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1053\/rmed.2000.0825","article-title":"Comparison of hydrogen peroxide generation and the content of lipid peroxidation products in lung cancer tissue and pulmonary parenchyma","volume":"94","author":"Zieba","year":"2000","journal-title":"Resp. Med."},{"key":"10.1016\/j.actbio.2021.09.051_bib0054","first-page":"13","article-title":"The Impact of Extracellular Ca(2+) and Nanosecond Electric Pulses on Sensitive and Drug-Resistant Human Breast and Colon Cancer Cells","author":"Kulbacka","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.actbio.2021.09.051_bib0055","doi-asserted-by":"crossref","first-page":"9935","DOI":"10.1039\/C8NR00640G","article-title":"A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration","volume":"10","author":"Cun","year":"2018","journal-title":"Nanoscale"},{"key":"10.1016\/j.actbio.2021.09.051_bib0056","article-title":"Rational Design of Nanoparticles with Deep Tumor Penetration for Effective Treatment of Tumor Metastasis","volume":"28","author":"Zhang","year":"2018","journal-title":"Adv. Funct. Mater."}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706121006474?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706121006474?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:48:58Z","timestamp":1761673738000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706121006474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":56,"alternative-id":["S1742706121006474"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2021.09.051","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endogenous NO-releasing Carbon Nanodots for Tumor-specific Gas Therapy","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2021.09.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}